Average Rating: 3.0 (912 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 1  Depression EPS (movement disorders), extreme weight gain, lethargy This anti depressant ranks at the top of of the list for weight gainers. I was also on risperidone for 3 months but kept gaining weight after going off probably due to this drug. Gained 20 more pounds after going off the risperidone while I was on this drug. Overall gain of 65 pounds only able to lose 5. BEWARE of weight gain and lack of energy. F 38 7 months
1X D
 1  insomnia dizziness, vertigo, headache, constipation, visual hallucinations, closed-eye hallucinations, hearing things that aren't actually there, sluggishness, daytime drowsiness, extreme sedation, blurred vision, impaired cognitive skills, confusion, very drugged up state, head bobbling, vivid nightmares, blank stares, absence seizures, drooling, weakness, difficulty walking DO NOT TAKE THIS MEDICINE!!! THERE ARE WAY BETTER MEDICINES FOR INSOMNIA OR DEPRESSION WITH BETTER RESPONSE AND REMISSION RATES THIS JUNK IS AWFUL NO CAP ON MY MAMA AND DEFINITELY DONT TAKE IF YOU ARE ALREADY ON AN ANTIDEPRESSANT IT WILL SAVE U TEN GRAND ON AN ER VISIT F 18 2 days
15 1X D
 1  anxiety depression no appetite numbing anxiety cognitive issues paranoia fast heart rate on higher dose. aggression severe. hopelessness. constipation urine retention causing severe uti and then couldn't stop peeing mania crazy thoughts all of it. a little mild sleep improvements but short lived. dreams. lethargy. don't take it. I had some hope because I had many side effects from others. now what. on other meds before pandemic but had issues severe reaction to pandemic exacerbated everything. F 66 10 days
7.5 mg 1X D
 5  Sleep None Great Med for Sleep. About 10 years ago I got very depressed/anxious and could not sleep at all. Tried all the Ambien, Lunesta, etc.... with little luck. They might allow me to sleep for 2 hours but not an entire night. Tried Trazodone with no luck. P Doc tried Remeron (Mirtazipine) as a last resort and it has worked tremendously for sleep - for a decade and counting. Most people get sleepier on lower doses like 7.5mg 15Mg or 30 Mg but 45 Mg is the best for sleeping for me. I recommended this to a friend as well years ago and he thanked me for telling him M 50 10 years
45 Mg 1X D
 5  Depression Tired first week. Weight gain 30 lbs withing 6 months. Not able to lose weight. M 62 5 years
30 mg 1X D
 1  my son was taking this for insomnia my 29 year old son was taking mirtazapine (the generic form of remeron). He had just received his masters degree in social work 9 months ago. He was in a new and very happy relationship and told me "this may be the one mom". Everything in his life was going extremely well including his job of 3 years. He started taking Mirtazapine and a few months later he shot himself with the gun he had for 10 years. This drug killed our son but big pharma continues to profit off of it. M 29 60 days
15mg 1X D
 1  Depression, sleep Broke up my relationship. Irritability, barking orders, forgetfulness, demanding, nasty attitude. Docs only care that it's not causing any issues with blood or urine tests . They could care less about the psychological effects. Or the effect it's had on my partner who has left me. Horrible drug. M 61 17 days
30mg 1X D
 4  Insomnia Tiredness, difficulty thinking, bit of weight gain. At 30mg severe gastrointestinal problems and dizziness. 15mg works well for my insomnia but it can be hard to get up in the morning the next day and my brain is also a bit foggy the next day. However without it I don't sleep and then it's even harder to function the next day. Tried increasing to 30mg for depression but I had severe nausea, fatigue and dizziness at this dose so doctor took me off it. Then I couldn't sleep again. Only gettong 2-4 hrs sleep a night. Now I am back on 15mg for 2 days and have to go through the initial adjustment period again which is annoying. Very sleepy the next day at the moment but this should subside. Overall it has been very helpful for me. F 43 3 years
15mg 1X D
 2  Anxiety Tiredness in mornings restless legs depressed anxiety still the same F 62 9 months
15mg 1X D
 2  Depression, insomnia, CFS Extreme hunger - no matter how much I eat I'm always hungry! And frequent urination, though I'm not sure that it is responsible for that. It helped with my insomnia, and I'm a bit less depressed, but this hunger is too much and it's getting worse, so I'll start cutting it down. M 26 4 weeks
30mg 1X D
 2  Insomnia asthenia (not fun), worse depression, numb emotions, forgetfulness, concentration issues, narcolepsy, random hand twitches, total exhaustion, agitation, appetite increase, super low sex drive, suicidal thoughts, atrocious vivid nightmares, My initial experience with it was positive just like most people have reported. I thought it was a miracle drug, given how good it was at eliminating insomnia. That only lasted a week or two, though. That initial thinking was brutally crushed. The medication cost gave me a lot of confusion could not remember a lot of stuff and began to experience terrible nightmares and random sleep interruptions that decimated my routine. Constantly fatigued, depressed, poor working memory, poor focus, random hand twitches, etc., even after 8-12 hours of sleep. It also has a super long half-life that can leave you with terrible side effects for nearly 2 days. It counteracted my Adderall XR completely and brought me close to experiencing a full-blown serotonin syndrome once. Once I was so desperate to get to work, but even after I took 60 mg Adderall XR (my usual dose), Remeron negated it so completely, I fell asleep less than an hour later. 120 mg Adderall XR also failed to keep awake. Micro-dosing (~1-3mg) worked for me (for a time) and gave me fewer difficult side effects (still felt them though, but its nothing compared to the disaster I felt when I was on 15 mg). Remember, even small doses eventually accumulate in your body if you take it every day-- avoid that. M 29 12 months
15 mg 1X D
 5  Depression and decrease appetite groggy in the morning, cheerful, hungry F 43 12 days
7.5 1X D
 4  sleep Some drowsiness, brain fog. I have had chronic insomnia for five years. Over the last four months it took a turn for the worse. This is the first medication that has worked.I am hoping that the side effects are more because of long term sleep deprivation rather than the drug itself. The only odd thing is that it produces strange dreams that can be tiring. Last night I had a dream where I was having hallucinations. On top of that I have lucid dreams, so I am not sure if I am awake or not. I cut my dosage from 15mg to 7.5, would cut it in half again if possible. Maybe after while I will go back to 15mg. Maybe I am writing this too early, only after four days but I am hopeful this is answer to really bad long term insomnia. M 59 4 days
7.5 1X D
 1  Depression, anxiety, sleep Massive weight gain, metabolic syndrome, prediabetes, dyslipidemia, fatty liver, akathisia, memory loss, cognitive impairment, flat affect, loss of interest, feeing robotic, less interest in friends and wanting to be isolative, developed skin picking behaviors and possible autism-like behaviors as well. This is a horrible medicine. I highly advise anyone to stick with the lowest possible dose (Preferably 7.5-15mg) and use only for sleep and for a limited duration of time. I took it at higher doses and for upwards of 9 years and it has ruined my life. I gained 60 lbs, developed a fatty liver and prediabetes. As I've been tapering it I've lost 25 lbs, basically a pound for each milligram so far. Over the years I became more and more flat, robotic, lost interest, no feeling towards anyone, feel isolative and don't want to be around people. I've experienced numerous cognitive issues which have gotten a lot worse as I've been tapering down- this medicine destroyed my brain and ability to think. Worst of all I've developed movement disorders upon tapering- akathisia/severe restlessness. M 25 9 years
 5  Depression with associated insomnia Nil This drug has been fantastic in addressing my stubborn insomnia. It worked wonders from my first dose and completely knocked me out for the whole night, without any next day grogginess or side effects. I take it prior to bed. I am also on Effexor for depression and the two antidepressants combined have vastly improved my mental state and my depression is very much under control. I am thankful I found this drug. M 41 7 days
 3  Sleep and anxiety Gained 10 lbs in the first week - this made me more depressed than before I went on it. Also I slept all day... 12-13 hours and couldn't get up. Then when I did I was moody and hungry. Not a fan of this med at all. Wouldn't recommend to those just having issues sleeping take Tylenol pm or sleep aid instead this is way too intense a drug for sleep issues F 32 15 days
 5  General anxiety disorder Sleepy the first week, but subsided. Increased hunger. Continuous weight gain, 30 lb. M 59 3 years
30 1X D
 1  Anxiety and depression Insane hunger and anger issues Did nothing positive M 45 90 days
 4  Insomnia Extreme hunger. It sometimes makes me so hungry that I have trouble falling asleep unless I munch a lot before bed. Another side effect is sleeping too much and daytime drowsiness. This side effect lessens after some time on the medicine. You can also cut the tablet in half or take a lower dose, eg. 7.5mg if it is to strong. Even though I was prescribed this as needed for sleep it also improves my mood, since it is an antidepressant. I also take Celexa for anxiety & depression. If your only taking Rem for sleep it works best if you only take it when you need it as you may built up a tolerance to its sedative properties. Another important thing I would like to comment about is that this drug often causes weight wain for some people, however I am lucky as no meds seem to have this effect on me. If weight gain becomes a problem you can talk to your Dr. about trying Trazodone which is a similar med but doesnít cause food cravings. Even though it still helps me sleep I have developed some tolerance to its sleep effectiveness over the years probably bc I take it almost every night. I have always taken a generic. I havenít heard of many probs with the generics, however the Aurobindo brand does NOT work for me for some reason. M 33 10 years
15 MG
 5  Depression, insomnia, anxiety The first two days were the worst. I was so tired I could barely function the next morning but day 3 onwards is crystal clear. This is the best thing that has happened to me (next to my husband and daughter). I used to have problems with my brain going a mile a minute and intrusive thoughts. It has stopped this. I can't believe how much mental energy was being used up living like I was before. Now I can devote more time to my husband and daughter. Before between life and work I was just surviving but now I'm thriving. It hasn't even been the full amount of time for it build up and it's changed my life! I may not sleep 8 hours each night but I've yet to have a single night where I haven't gotten a minimum of 5 hours. Zoloft failed me and I tried to kill myself on it. It took me 15 years to be brave enough to add something new to my current medication mix (dexedrine for ADHD and Wellbutrin for anxiety and depression) but I'm so glad I did. How to not get fat: 1) count calories because your body will tell you it's hungry when it isn't. Make sure you stay within your limits. 2) have willpower to not eat when you're hungry The people that gain weight on this are the ones without willpower. They made themselves fat by eating not the pill. F 33 5 days

REMERON  (MIRTAZAPINE):  Mirtazapine is used to treat depression. It improves mood and feelings of well-being. Mirtazapine is an antidepressant that works by restoring the balance of natural chemicals (neurotransmitters) in the brain.   (Sources: U.S. Centers for Medicare Services, FDA)