Reviews for TAXOL

26 ratings: (taken because of bc cancer, side effects include neuropathy)

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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  2b met. Breast Cancer Terrible neuropathy in feet had nerve test permanent nerve damage. Should have used different drug or been administered drug differently. I blame doctor for that. But after nine years cancer free but also thank the Lord for that It has destroyed my life 56 3 months
??
11/20/2019
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 1  Stage 3-A lung cancer Long term side effects I'm 8 years out. I still have terrible insomnia. Neuropathy in my hands & feet. Chronic fatigue. Small end nerve damage from head to toe.Unable to concentrate multi task confusion.Memory & time loss. Muscle & joint pain. Acne. PTSD. Depression. Headaches. I was never told about these side effects. Nor was I told they could be life long. I had neurological testing done in 2014. I was told I have Dementia caused by chemotherapy. The chemo cocktail I was given included Taxol Carboplantin Benadryl & other meds. Also did 6 wks of radiation 5 days a wk while doing chemotherapy at the same time. F 42 15 weeks
50
4/18/2018
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 3  Metastatic Breat Cancer Terrible peripheral neuropathy in feet. Extreme fatigue. Worse is the lung damage (irreversible, I'm told..) How can a drug that should be beneficial to me destroy my lungs?? Is this the only chemo drug used for metastatic breast cancer? As for all the scans and blood tests, the Taxol did OK. F 77 10 weeks
1X W
3/18/2017
 1  Breast cancer Severe neuropathy Question your if side effects can be perament F 65 1 days
12/27/2015
 5  Stage 4 Breast cancer Total hair loss for entire body, peripheral neuropathy, joint pain, neutropenia , tolerable fatigue, rapid heart rate Saved my life and thankful for this drug. Breast tumor and 2 small areas in liver were completely gone after first month (3weeks on & 1 week off ) of treatment with concurrent palliative radiation of lower back. Now 7 months later and addition of Avastin at month 5 , I am NED (no evidence of disease) and even bone detioration is gone. I started with mass in left breast, 2 small areas in liver, 3 metastases to the spine and severe pelvis, ribs and sternum bone lytic lesions. F 45 7 months
90mg
5/26/2014
 4  Stage 4 lung cancer Slight neuropathy and swelling of feet; slight tingling of fingertips; almost complete hair loss including all body hair. Side effects not suffered include nausea, intestinal problem, heart or kidney problems. I have had 20 injections (each lasting 2 hours) of Taxol in the last 26 weeks. I take 3 weeks in a row, skip a week, and then start another 3 weeks of injections. Currently I will be skipping 3 weeks (impending cataract surgery) and resuming weekly injections on June 13th. I have found that this skipping allows my body time to rebuild and not leave me completely drained and weak..The day of and the day after chemo are my coming down from the steroids days. Days 3 and 4 after chemo are generally my "don't do anything" and rest days. Days 5 and 6 are my "normal" and productive days. The latest CT scan shows that Taxol has reduced the cancer mass in my lung to one-third the size it was before Taxol. Prior to Taxol I was on Carboplatin every 3 weeks, however this chemo still allowed for the effusion to build up in my lung. Since starting on Taxol last November I have not had the need to have my lung drained of effusion (thoracentisis). As a comparison, between my diagnosis in June 2011 and my last thoracentisis in Nov 2011, a total of 11.3 liters of fluid at 7 different times were removed from my left lobe. M 66 26 weeks
180 MG 1X W
5/17/2012
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 3  Adv Metastatic BC stage 3C grade 3 I was treated in May 2006 first with A/C and after no affect 6 weekly doses of TAXOL. I had lost my hair from A/C treatments but after taxol I lost ALL my body hair. The neuropathy began my second treatment which was done while I had shingles. I know I am alive today because of this drug but I hate that for so long Doctors have not taken the long term effects of Chemo drugs especially taxol seriously. After almost 6 years I continue to walk like an 80 year old. My fatigue is severe, I have constant bone pain in both my lower legs, numbness, burning, aching, and shooting pains in my feet and hands. I am a single mom, a middle school teacher, and I haven't been able to work a full year since treatment. I have to take pain medications to work and it is depressing not to be the active strong person I was before treatment. I am thankful to be alive, yes, but please give us the information, care, and belief following treatment as well. I want to live happy not be in horrible psn and a burden to my kids. My older two live at home because of this and I hate that this has changed their lives as well!. F 50 6 weeks
max dose
4/10/2012
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 3  stage 2 breast cancer Put on after severe neuropathy caused by taxitere. Neuropathy continued to affect my feet but gone in hands. Lost 17 finger/toe nails. Extreme fatigue but continued to work from home office all but day of treatment due to time. Cracked corners of mouth, gooey mouth or cotton mouth. 2 weeks after last treatment extreme leg/joint pain and edema in legs. Still unable to do many things with my hands; buttoning, picking things up, holding onto things w/o dropping. Loss of balance, difficulty walking. Hoping these subside quickly. F 40 9 weeks
4/3/2012
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 3  stage IIIA breast cancer peripheral neuropathy after 8 treatments, severe joint and bone pain, felt like I was 90 years old (I'm 53). Much easier than AC but long term effects more pronounced. My doctor didn't have any answers for the long lasting joint pain but it DID disappear about 18 months after last dose. Previously had trouble getting out of a chair, felt stiff and sore, but after walking a few steps it would improve. I didn't think it would ever go away but happy to say there is light at the end of the tunnel! Still occurs once in awhile after a long day at work or exercise. No recurrences (yet) in 2 years so hopefully it was worth it. F 53 12 weeks
1X W
10/5/2011
 5  stage I grade 3 triple negative BC intermittent very mild neuropathy, some stumbling, but not too bad. a little fatigue, but not too bad. After the Epirubicin and Cytoxan, the Taxol is wonderful I think the pre-meds are the primary cause of my tiredness and malaise for a day or two after the treatment. my WBC and RBC counts are low, but staying constant I am ravenous due to the dexamethasone pre-med, but try to eat lots of proteins to keep my blood counts up. I take a couple tablespoons of blackstrap molasses every day, and I'm convinced that that is helping with the blood counts. F 49 6 weeks
12 weeks 1X W
5/15/2011
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 2  Stage 2 - Triple Neg -Breast Cancer Peripheral Neuropathy set in following the first Taxol treatment, hands first then feet. I lost all skin on my hands, numb at the tips, sharp electric shock feeling when I touch things. Side affects got worse following each treatment. Lost toe nails after second treatment and big toes hurt, finger nails are now purple and they say the finger nails will probably fall off too. The pain is intolerable at times, especially at night. After a few weeks it has gotten a little easier to walk, hands are arthritic feeling, ankles hurt - I just hurt all over and I feel 90 years old instead of my usual active and happy self. Not sure if it was worth it yet as I had chemo first, with surgery to follow. I cherish my quality of life over length and this is far more severe side affects than I was told to expect with only 4 treatments. They gave me pain meds the first few weeks, but now suggest the symptoms should be subsiding and I should use natural remedies and buck up and it will go away in Chemo is poison for some and medicine for others and doctors are not sure how anyone will react for sure. More research is needed to find a cure, but in the meantime more emphasis should be spent on treating the side effects and not just the cancer. Side affects are real and most often pushed off onto the aides and nurses to treat and unless you get a really qualified nurse, this can be emotionally and physically very difficult. F 51 7 days
2X M
2/20/2011
 3  Stage 3 BC Much easier than AC. Initially, seemed like a walk in the park. After a few weekly treatments, joint pain, extreme fatigue, mild nausea, neuropathy, acne from steroids, memory impairment. My hair grew back while on Taxol! F 40 12 weeks
1X W
11/25/2010
 3  Stage 1 breast cancer Extreme fatigue - I was unable to work, read a book or, most days, even watch TV, muscle pain - especially in legs, complete hair loss midway through treatment, eventually toenails turned blue and split, premature menopause for 16 months after treatment, diarrhea, acid reflux, tinging feet and hands (neuropathy) that lasted a few weeks post treatment, but I id well with this side effect as it was only mild and went away very quickly when I was done with chemo. The last two weeks of treatment, I also got serious nausea. The fatigue was so bad by then that I could not drive a car for more than 10 minutes. It took about 3-6 months to begin to feel myself again. I also took this med with weekly herceptin, so it is not possible to precisely know which medication caused which symptom. But I am two and one half years past treatment, and I feel 95% recovered. Not fully regained my energy - yet. This medicine obviously affects people VERY differently, as working during treatment would have been a complete impossibility. F 45 12 weeks
unsure 1X W
11/7/2010
 3  stage 2 breast cancer Experienced the classic symptoms during treatment. However, after treatment, peripheral neuropathy in my feet. Numbness in all toes. Tingling in all toes. All toenails and fingernails are falling off and have fungus infections. Balance and walking are severely affected. Help! What is the treatment for the fungus???? F 64 56 days
30mg 1X W
7/7/2010
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 3  breast cancer I took Taxol weekly for 12 weeks, along with Herceptin (I just finished my year of Herceptin). I've been off Taxol since September 2010 and while my counts and general health were good throughout, I had some severe neuropathy and balance issues. I tried Lyrica, gabapemtin, glutamine and lots of naturopathic remedies. I still have intermittent intense discomfort in my feet, muscle weakness, balance issues. I am an active 55 year old and it has definitely diminished my level of activity. I still feel I did the right thing, despite the neuropathy. I had a recurrence (actually a totally new breast cancer in the other breast). Was HER2 neu positive, too, so feel I have to deal with the side effects as I want to stay healthy!!! F 55 12 weeks
100 mg 1X W
5/31/2010
 3  Stage 2b Breast Cancer Four A/C treatments with minimal side effects (fatigue & hair loss). Thought Taxol would be a breeze but I was wrong. The bone & muscle pain (mostly from the waist down)started 3 days after my first Taxol treatment and was so severe I took Darvocet that was leftover from my surgery. Pain lasted 5-6 days. Second Taxol the pain started 2 days after and lasted 9 days. Third Taxol the pain started the next day and lasted the full 2 weeks until my last Taxol which was 2-1/2 weeks ago. Pain is still incredibly intense. Initially the pain was more in my hips, legs and feet. Now it's also in my shoulders, arms & hands. I also have neuropathy and darkened nail beds but I can deal with that. I had 4 A/C treatments with very little side effects. The Taxol has definitely been much harsher on my body. I have a very high pain tolerance and the bone and muscle pain is about a 9. I've been on Vicodin since the 2nd Taxol and have had to increase the dosage with each treatment. The pain came on earlier and lasted longer with each Taxol treatment. I called my oncologist 2 weeks after my final Taxol and he increased my Vicodin dosage and also prescribed a muscle relaxer. Not sure how long this will last but I'm hoping it won't be much longer. I had the option to go with the 12x weekly Taxol dosage but thought since the A/C was so easy that I'd do the 4x every other week. Not sure if it would've made a difference. F 47 8 weeks
2X M
5/26/2010
 1  breast cancer stage 2 grade 3 ducta 8 months after my last treatment I am still experiencing peripheral neuropathy in my feet, ankles , hands and wrists. My pain was 10 out of ten (agony). I have numbness in both of my feet that cause my mobility and balance issues. I have fallen an injuried myself because of the numbness in my feet. I wear protective shoes at all times to prevent injury if I step on something and to give my balance. There is not a time that I am without pain. I have tingling in my ankles at times of shooting pain. In the morning I my hands are curled up and in pain. I have not returned to work because my balance is so poor. The quality of my life has diminished. At 53 years of age I feel 90 years old. I have tried Lyrica , gabapatene, and amitriplyne as well as Vitamin B and glutamine. None have been able to relieve the pain and often have left me in a bit of a mental fog. I have always been physically active and have tried to continue to exercise by riding my stationary bicycle, walking,( with the worst gait possible)yoga, weight lifting rehab pilates on a reformer and just started dragon boat racing. Any exercise you can do sitting down . I have tried to golf 9 holes riding a cart however my ankles are so painful afterwards I con't know if it is worth it. My typing accuracy is dreadful since I can't feel the keys. Taxol might have saved my life from a recurrence of cancer but it also stole the quality of my life and livelihood. All I have been told is that it might get better over time. One can only hope. I have just recently been seen by a neurologist. When I told my oncologist after the first round of taxol that it was the worst pain I had ever experienced that he joking said that I had never experienced labor as if that would be more pain than I was experiening . I told HIM, HE never experienced labor either and not that type of pain now for 8 months.... I have tried everything I can do from drugs, diet, exercise, mediation etc...however I have no control when or if the periperal neuropathy and my mobility will F 53 4 times
4X O
5/20/2010
 4  Stage IIIa BC, one side mastectomy Painful brittle, yellow nails; mild neuropathy in fingers, tired I took 12 weekly Taxol Tx after AC for 2 months every 2 weeks. Taxol was so much easier! Dexamethasone was giving me trouble (water retention and weight gain of ~12lb by the end of tx). I am now 1 month after tx and feeling really well. I was exercising throughout my treatment, walking 4-9 miles almost every day, swimming several times a week and working almost full time. I even went skiing in the Rockies while on Taxol! I believe that good physical condition before dx and continuous exercise during tx helped me to go through this difficult time. It was not exactly a walk in the park but close enough. I started radiation now, Arimidex and Clodronate and still run. F 59 12 weeks
1X W
3/13/2010
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 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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