Average Rating: 3.0 (920 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 2  Depression felt like zombie. Felt and did nothing. Restless leg syndrome at night. Side effects with no benefits. Sexual side effects, of course. I've taken 8 other antidepressants, and this is the only one that taught me what people mean when they say their doctor gave them a drug that made them a zombie. M 40 14 days
75mg 1X D
 2  GAD/major depression At first this drug worked great for me. It even gave me sex drive back after Zoloft took it away for years. But then after each year my dosage kept going up and up because I still felt depressed and anxious. We even added other meds to help with the anxiety (Wellbutrin, hydroxine) and it made it worse. I've gained about 25 lbs and became very isolated on Effexor. No energy, always moody, unmotivated, sad.. Trying to withdrawal from it is a nightmare. I'm praying I can get through this withdrawal and be done with this horrible drug. Stay away from this medicine if you can. Side effects of withdrawal: severe dizziness, nausea, insomnia, sweats, crying, extreme hunger, irritability, swooshing in my head and ears, concentrating problems, hot flashes, and feeling like I'm going to spew my guts out. I'm tapering off of 275 mg and I'm now on 37.5 mg and it's still a horrible withdrawal feeling on the 37.5 F 37 3 years
275 MG 1X D
 1  Depression and anxiety Memory difficulties, decreased sexual interest, no emotions, no interest in activities The withdrawal symptoms are horrible. I don't understand why any health care provider would prescribe this medication to anyone. If I live through the symptoms of dizziness, sadness/depression, mood swings, suicidal thoughts, anxiety and nausea, I will consider myself lucky. F 60 21 days
1X D
 2  Depression and anxiety IBS-D Dry mouth and throat, achy muscles, EXTREME sweating, headaches, total loss of sex drive. I don't think my depression and anxiety were bad enough to deal with the side effects of this med. F 52 2 months
75mg 1X D
 5  Menopausal Hot/Cold Flashes No sex drive and a lack of sensation in the genital area, the worst GERD, higher blood pressure, higher cholesterol (in a person who previously had a average bp 90/70), nausea, vomiting, diarrhea, constipation and poor bowel movement because the anal sphincter becomes impaired on Effexor. Emotions: Inability to cry, just numb and slightly pissed. I was initially prescribed 37.5mg. The hot/cold flashes were reduced by 75% in the 1st 2 weeks. After 6 mos, not so much. Needed 75mg to maintain. After 18 months I was feeling really good, too good to be true. Then I couldn't stay sleeping at night, my hands started to shake often, suddenly my health stats started to decline (ie:blood pressure, cholesterol, sugar) sweating profusely all of the time but not feeling hot. The hot/cold flashes that I experienced were far worse then any of these symptoms. If they return I will take Effexor again. Until these side effects appear again. Effexor gave me energy to get out of bed and take better care of myself without those awful hot/cold flashes. However, detoxing/tapering/titrating from Effexor is challenging. I am currently detoxing alone taking 1 every other day for 1 week, than every 50 hours, 55 hours, etc. until I am done. Will do it over a course of 2-3 months to minimize side effects. So far, brain zaps, dizziness, slight nausea; which are distracting but not more than awful hot/cold flashes. F 56 2 years
 2  MDD, GAD, PTSD Nausea, headaches, twitching, constipation, increased hunger, increased weight gain, worse body odour, heat intolerance and fatigue Didn't work that well for my depression and gave me a bunch of awful side effects. Withdrawal is awful. Do not recommend. F 25 1 years
225 mg
 4  Depression and anxiety Loss of sex drive, muted emotions, weight gain Withdrawal is miserable, brain zaps, anxiety, tearfulness, high BP, bad dreams, irritability. I have had very limited support in going off medication, other than taper slowly. I have to work and take care of people! Going off slowly. 150 to 75 mg, been taking that for a month, now down to 37.5. Will probably take that for at least two weeks before tapering further. Take a different medication! F 54 10 years
150 1X D
 2  Depression/anxiety RLS, crazy dreams, tired all the time, anxiety was worse than before, head feels swimmy after stopping, with worse dreams. F 33 5 months
150mg 1X D
 1  Anxiety and depression This medicine helped with anxiety and depression more than most I've tried however the cons outweighed the pros. NO organs in a year, I couldn't find my husband who I KNOW I'm attracted to, attractive. Sex is once a month and its the biggest chore ever which is not me. I am fat. Gained 30 lbs in the first 3 months no matter how little I ate or how much I excersized which was a LOT. I am drowsy like taking benadryl or sedative all the time! O sweat buckets. My boobs even sweat!!! I had headaches galore and extreme lights sensitivity. This is to name just the cons I can think of. I am currently weaning of the MINIMUM dosage it is hell that I would only wish on my worst enemies. I feel like I'm being electrocuted with a light socket. My head hurts my eyes feel oddly swollen and painful. I feel like I need to throw up. I took painkillers for the withdrawal symptoms and even that doesn't do a thing. I feel like I'm dying a very slow and miserable death. F 30 1 years
35.5 1X D
 1  Anxiety and Panic Felt lethargic. Made mood worse. Did not do anything for my condition. SSRI & SNRI are so overrated drugs. I do better on older meds like Tricyclics. M 24 6 weeks
 2  Anxiety depression Metallic taste, dry mouth, nervous, hot, sweaty, odd dreams, nauseous, increased heart rate, and more F 39 2 weeks
 1  general anxiety disorder Insomnia, metallic taste in mouth, increased anxiety. Already taking Lunesta as sleep aid. Doctor experimenting on monthly basis. Can tell where this is headed, so stopping now. As a chef, the last thing I need is no sleep and an impaired palette. M 53 8 days
 3  depression Youíll get a hell of a cardio workout on this thing bc you wont be able to achieve orgasm F 51 3 days
 1  Bipolar manic depressant When I first 🌟 taking effexor I was in a Florida prison they did not say it was an addictive medication then I was transferred back to county to clear up some loose ends immediately I started having withdrawals and bad night sweats diarrhea headaches throwing just to name a few I rode it out and never took it again ask plenty of questions before taking this medication 100 days
 1  Migraines Worse feeling ever! DO NOT TAKE Had insomnia within 2 hours of taking it before bed, brain zaps, sweating, nausea, food aversion, migraine. Pumped water to flush it out of my system. Lost a whole day feeling like absolute death. F 47 1 days
75mg 1X D
 1  Major Depressive Dis./Panic Dis. Food aversion, weight loss, nausea, exhaustion, insomnia, brain zaps, cognitive dysfunction, increased depression, paranoia, panic attacks so severe I could not leave my house, memory loss, SEVERE mood swings (crying uncontrollably for no apparent reason to uncontrollable rage that made me want to physically hurt myself & others) Over a period of several years my dose kept going up from 75mg to the max of 300mg and it was effective without too many side effects. When I moved to Florida the Drs here put me on between 75-150mg & my life has been a living hell for the past 10 years!! My recent suicide attempt put me in the care of a Psychiatrist who really researched this & found that some people just cannot be treated at a lower dose once they have taken a higher dose as the Effexor is not only NOT treating the depression but is triggering the brain in severely adverse ways like causing all that uncontrollable rage I mentioned. Like flipping a switch & Iíd become this absolutely despicable person. Seriously felt like I was possessed by something so truly evil that death was preferable. F 43 6 years
 1  Depression Severe nausea, diarrhea. Lost almost 20 lbs. over 2 weeks. F 64 70 days
Don't remember
 3  depression Totally speed, I had to take benzodiazepine to balance the effect. I stopped it once, it tooks me around a year to get off it, due to strong side effects. Last year I fall into the worst bout of depression I ever had and I was on Effexor when that happended. 2 days after going on 150 mg, I had dissociation and akathisia. Dissociation didn't disapear when going down to 75 mg. It took months. Very hard to stop. F 44 15 years
75 mg 1X D
 5  Panic Disorder/Depression/OCD Sleepiness, Memory problems, word finding problems, and waking up the next day is very hard, grogginess for at least first 2-3 hours...Does a number to slow your mind up... Side Effects aside this is my go to drug. Has been for 15 years from 50 mg to 100 mg. The drug always helps anxiety/depression for me. M 36 15 years
50-100 Mg 1X D

 1  Depression along with Remeron High blood pressure, dry mouth, high blood sugar, weak dizzy and sometimes passed out and didnít remember it except when I was pulling myself up off the floor I am looking desperately for something that will knock out all the symptoms. They tried giving me insulin. It did not remove one bit not one number. What did work was an IV. I have requested my doctor leave in one of those IV things so I can continue to give myself Saline solution. That does work wonders I donít want my pancreas destroyed over this. Blood-pressure still in issue anybody have any ideas. I hope everybody knows these are black box prescriptions, in another words that what you use if nothing else works stay away from them F 49 4 months

EFFEXOR  (VENLAFAXINE HYDROCHLORIDE):  Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   (Sources: U.S. Centers for Medicare Services, FDA)