IMITREX Reviews (SUMATRIPTAN SUCCINATE)

Average Rating: 3.6 (599 Ratings)

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 MIGRAINE HEADACHES UNCLASSIFIED

 Type: Rx Drug

  

IMITREX  (SUMATRIPTAN SUCCINATE):  Sumatriptan is used to treat migraines. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Sumatriptan belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain. Sumatriptan does not prevent future migraines or lessen how often you get migraine attacks.   FDA Approval Date: 1996-12-23 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMITREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Chronic migarine This is referencing Imitrex injection; sudden increase of migraine pain, like being hit with a blunt object. Bad enough to cause crying. Reaction at injection site, a pair of bumps (welts, hives?) about 1cm below injection. Will NEVER take again. Have taken before in pill, nasal packet, and injection form. Had never had a reaction previously, but received no relief except by injection. After reaction, will NEVER take again. F 22 9 years
7/25/2009
 4  Migraine Immediate: sleepiness. 12+ hours after: Shakiness everywhere - hands, knees, even abdomen. Cognitive difficulties - difficulty concentrating, reduction of inhibitions, difficulty with complex analysis. Note: some side effects are hard to differentiate from migraine effects. I have found ANY aborted migraine has physical and cognitive effects the following day, even if a different treatment is utilized. For migraine sufferers, triptans (like Imitrex, Maxalt, etc.) are an almost certain cure. I prefer to deal with ANY medication side effects, rather than a set-in migraine, which is the worst pain I've ever experienced - even worse than 32 hours of unmedicated back labor. NOTE: serotonin levels typically decrease before a migraine; triptans increase serotonin. Here's another abortive that has worked for me: 2 Aleve and two 5-HTP (tryptophan, an amino acid). Tryptophan is found in poultry and is what makes us sleepy from eating turkey. Tryptophan is also a chemical precursor to serotonin, passes the blood-brain barrier, and increases serotonin levels in the brain. This combination of Aleve and 5-HTP has aborted 3 migraines for me, with no side effects the following day. F 34 6 years
7/24/2009
 5  migraines in head and abdomine for my first shot in the arm, I had a tight feeling in my chest, but I relaxed and it went away after a few minutes. I'm finding the injections are leaving bruises that last quite a while. Even after the bruises have faided, even months later, you can still see a faint outline of a light almost see through spot same place and size the bruise was. so far, I'm just adding to the collection. Am curious as to why this is happening and if anyone else has had this happen. F 33 8 years
7/6/2009
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 1  I was injected once for migraine. I had horrible chest pain, loss of cognition, ached and was in bed for months. I was put on disability very quickly, as it was obvious how sick I was. It is 13 years later, and I still suffer from chronic fatigue and cannot work. I really wish I had sued. People, Imitrex causes heart palpitations and other side effects. Research on the Internet to learn how dangerous this drug is. Glaxo knows about these deaths but is choosing to ignore it. Implore your doctor to give you pain medication instead. I was lucky to get a prescription, but if your doctor doesn't prescribe pain meds, you can get them on the Internet. It's better than dying! M 60 1 days
7/1/2009
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 5  lifelong migraines None after first few doses years ago (warmth around head and neck). New: sleepiness. Have begun to experience sleepiness after 25mg. I consider Imitrex to be a life saver and miracle drug. Tho I'm getting older and a couple of doctors have suggested I shouldn't take it, I'm fortunate enough to have a doctor now who suggests no limits for me. I have daily (on average) headaches, mostly tension-headaches leading soon to migraine. Imitrex always works. I've told everyone if they kill me, I'd rather die than suffer for the rest of my life with migraines. I've come to this site just to check out prevalence of sleep after Imitrex. Common! Perhaps more so with age? It contributes (along with other drugs) to dopeyness for some hours. Watch out for beer, clonazapam and Imitrex unless you need a sleeping pill! M 68 15 years
6/23/2009
 2  severe, painful visual migraines immediately upon first dose experienced chest pain and pressure, sweating, anxiety, nausea, and an overall feeling of panic and unwellness and no relief from any migraine symptoms. the feeling was very similar to narcotic withdrawl. after the chest pain passed the other symptoms continued and i vomited violently and was weak (like the flu) and had to lay down and sleep for several hours. horrible, HORRIBLE reaction. would never, EVER take this drug again i would not discourage others from trying it because it causes some people great relief, but it my case it was horrendous. F 32 1 days
6/22/2009
 5  migraines I experienced all the weird ones: collarbone tightness, difficulty swallowing, achiness, swollen tongue, aphasia, clumsiness, feeling intoxicated . . . UNTIL I learned to take one Aleve with the Imitrex. For a mild migraine, I can take 25 mg of Imitrex and one Aleve, lose the migraine within 30 minutes, and never have any side effects. If I have to take as much as 100 mg of imitrex, I still feel sleepy and intoxicated, but have none of the other symptoms. I've heard that Treximet and Maxalt have the same medicine in them as Aleve, but now that Imitrex comes in generic form, it's cheaper for me to buy a bottle of Aleve than try one of those new meds. I would like to try a preventive medicine because I have at least two migraines per week. Has anyone had good success with a preventive? I cannot seem to establish any triggers for my migraines other than a STRONG hereditary propensity. F 38 2 years
6/20/2009
 3   I have taken this medicine for a couple of years now. It has always made me feel extremely 'weird' immediately after dosage, weak and shaky. For up to 24 hrs after dose I am achy all over, similar to flu symptoms. In the past year I have experienced severe nausea/vomiting after taking, unless taking it and going to sleep immediately. Imitrex does get rid of the migraine almost instantly, but I only take it if there is no other treatment or options available due to the rotten side effects. F 33 2 years
6/17/2009
 4  migraines Tightness in chest/difficulty breathing, nausea, fatigue, felt a little "disconnected" from my body, slow reaction time Normally I am able to take one 100mg tablet and it will relieve my migraine within 30-60 mins. The side effects are generally mild in this situation. Occasionally I will have to take a second 100 mg tablet to get rid of my migraine, which makes the side effects much worse. I would then have to sleep for several hours and feel lots of nausea. However, this is still far preferable to the severity of my migraines. F 25 2 years
6/16/2009
 4  Daily migraines for 38 years Very tired and sleepy, frequent urination. I started at age 40 with migraines 1 to 2 times per month. They became more frequent as I grew older, now have them almost daily. I avoid foods that trigger migraines, always wear sunglasses outside (often inside), and stay away from fragrance and chemicals as much as possible, but I am under a lot of stress, even as retired. I limit my computer time to 45 minutes 3 x daily and TV to 2-3 hrs in evening. I now have to take Imitrex almost daily but fear the side effects and possible rebound from Imitrex. I seldom take other pain killers or other prescription drugs. Fortunately, I have low blood pressure and a good heart. F 78 18 years
6/15/2009
 5  Migraine headaches Have had migraines since I was about 9. Diagnosed finally at 18! Side effects include: injection site welt, racing heart feeling, adrenaline rush, tighness in neck, the urgent need to pee soon after taking, and a real hungriness after headache has disolved. I prefer the shot more than the pill, as I feel I usually get a rebound headache withing 24 hours of taking a pill, but not with a shot. Am worried about long term effects- kideys, heart, eyes? I found a study online from Europe where they found something like maccular degenration of vision over long-term use. Yippee. This damn thing is a miracle, but nobody has used it for a lifetime yet to show us what can go wrong. Also, I hate relying on pharm companies so much. I do feel anxiety if I go on vacation and happen to forget packing a small supply of medicine. Life support. F 25 7 years
6/11/2009
 5  Severe Heaches None This drug has been a miracle for me! Other than occasional drowsiness and/or weakness and heaviness in the arms, this drug has been wonderful! I get more side effects from Excedrine that I do from Imitrex. Fantastic for me! M 48
6/3/2009
 5  Cluster Headache The only side effect I experienced was with the imitrex injections. I was having 5 clusters a day and was using to many injections. The imitrex injections was causing more headaches from using too much. I have had no side effects of the imitrex pills. However because it is cluster headaches the pills only work if I take them before I go to sleep. That way I prevent the headache before it comes on. The cluster becomes full blown in ten minutes but it takes the pill twenty minutes to work so the only way for the pill to work is to take it before I go to sleep. I have had cluster headaches since I was a teenager. They come along every year and a half to two years. They last three weeks to six months. During the cluster period I have them every night and sometimes during the day. My insurance will only cover the imitrex injections or the pills every twenty four days. I get two shots or nine pills every twenty four days. The rest of the time I have to deal with the pain. Any suggestions are welcome. F 53 20 years
6/3/2009
 1  Cluster headaches/migraines I took it once and it relieved the headache, but the side effects have been HORRIFYING!!! I could not walk, my tongue was swollen, couldn't swallow, dry mouth, felt like collar bone was broken, entire body ached severely- joints & muscles, worst of all.. my forearms hurt so badly I can't even pick up our 1 yr old. I have no feeling in my fingertips and cannot hold a pencil or a fork. It has been 4 days and only 1 50mg dose. I have been totally debilitated. I am worried the damage could be permanent. It's just not natural or normal to treat your body this way. I would NOT receommend this to my worst enemy. M 40 1 days
5/31/2009
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 5  Cluster Headaches The injection experience is one with a set group of sensations. First, within 3 minutes of the injection, there is an additional, short ramping up of the pain level of the cluster headache. This is followed by a gradual, with each breath, alleviation of all symptoms of the intense pain. The only time I had a side effect was taking it once while overheated in the sun. I developed a large welt around the injection site that ceded within 30-45 minutes. Imitrex injections are incredibly effective for me and as a cluster headache sufferer have changed my life. M 47 3 years
5/27/2009
 5  Migraines After I first take it, I feel strange. It's a feeling similar to an adrenaline rush that, when over, leaves me feeling weak, tired, and shaky. I also get an unpleasant tingling sensation in my jaws when I bite into food, but this only lasts through the first several bites. The good news is that once the side effects are gone (within an hour) the headache is too. Sometimes the headache comes back; I don't know if that would be classified as a rebound headache, or if it's a particularly stubborn headache that would have lasted a few days anyway. I take this medicine 1-4 times a month for mild to moderate migraines, and it's been quite effective. I could do without the side effects, but I don't take the pill unless I'm already suffering, and I'd rather suffer a few additional symptoms for an hour or so than drag around with a migraine for 1-3 days. F 39 15 years
5/10/2009
 1  migraine doctor gave me this i took the pill. when to eat with my husband. then with my first bite of food my jaw started to lock up, I stopped, perplexed, tried again, this time burning sensations through my gums/jaw and face. I almost screamed. when it hit my neck and arms burning i could barely move and had to be rushed home. very scary. i slept it off for 2 hours . woke up feeling hungover with a dull throb in back of my head. im scared to take it again. F 27 1 days
5/5/2009
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 4  Migraines Tightness, tingling, burning, slightly uncomfortable, didn't want to eat I am new to taking Imitrex and my doctor had told me about the side effects. I didn't realize what he really meant until I took it for a migraine I felt coming on (7:30 PM). I was watching a movie with my son and we were eating popcorn. All of a sudden I felt really uncomfortable. I had a sunburn on my arms and the back of my neck and it started burning like someone had a hot pan on it and it almost felt like it was going to bleed. My chest became tight and I had a tingling in my head. The uncomfortableness lasted until I went to bed (10 PM). By that time the headache was gone. Yes this medicine works and I can deal with the side effects. F 27 3 weeks
5/4/2009
 5  Migraine I generally feel a slight heaviness in shoulders within the first 30 minutes after taking pill. I have also noticed a stinging, tingling sensation in my jaw off and on during the first few hours after taking the pill (noticeable, but not painful per se). Other than that, just moderate drowsiness. The side effects I mentioned are mostly mild, and are very much worth the payoff -- no migraine headache! This medicine has made my quality of life so much better. F 31 1 years
4/8/2009
 1  Migraines PERMANENT nerve pain in my cheeks. Also, neck and shoulder pain that hasn't gone away. WAS NOT there before taking this garbage. I wouldn't take another one of these pills if you gave me a million dollars. If you are having neck and sholder pain after taking it STOP NOW. There is a good chance that will get worse and not go away. This stuff is crap. My own dr. wondered how my healthy heart would be effected after being on it. No history of heart problems so that got me wondering. I have not taken in over 2 years...pain in cheeks slowly going away...shoulder and neck pain (esp. right side) persists. F 49 6 years
3/29/2009

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