IMITREX Reviews (SUMATRIPTAN SUCCINATE)

Average Rating: 3.6 (599 Ratings)

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 MIGRAINE HEADACHES UNCLASSIFIED

 Type: Rx Drug

  

IMITREX  (SUMATRIPTAN SUCCINATE):  Sumatriptan is used to treat migraines. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Sumatriptan belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain. Sumatriptan does not prevent future migraines or lessen how often you get migraine attacks.   FDA Approval Date: 1996-12-23 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR IMITREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Migraine dizziness and drowsy-thought I would be able to drive to work. Had to go to bed for the day instead. This was my first time taking Imitrex despite being a long-term migraine sufferer. Initially, I took 50 mg. I immediately got dizzy and drowsy. The migraine did not subside after 2 hrs and some had recommended taking a second dose, so I took another 50 mg. I was quite nauseated, but kept it down. Difficult to say whether intensity of migraine and nausea at this point was due to imitrex or was my typical ramping up...very typical for my migraines to get worse a few hours they start and for me to start vomiting at this point. I went to bed for another 4 hrs and nausea subsided-headache got a bit better, but not entirely. I usually take ibuprofen, so I asked pharmacist if I could take it after taking Imitrex. He said yes, and some meds are coming out with both. I took 400 mg of ibuprofen and 2 hrs later the migraine was pretty much gone (I always have a dull ached for rest of day..)! Hmmm. So, I am not sure whether Imitrex helped or not in the long run, but it certainly didn't work instantaneously like it does for some. F 45 1 days
100 mg 1X O
2/18/2011
 5  Lotsof migraines Never experience any side effects. Have suffered migraines for over 20 years both with the aura and without. Tried everything available, told me I would grow out of them. Twenty years later I still have them. Take Topamax twice a day to help alleviate the amount I get a day. But if it were not for Imitrex to take the pain away, OMG!! It has always worked for me. I get the 100 mg pills and cut them in half so I really have 18 pills for the month because I get quite a lot of migraines. I would finish the nine pills we are allowed in no time. 50 mg works most of the time but have had to take 100 mg sometimes. I do love Imitrex and hope to God I never become immune to it. F 47 10 years
50 mg 1X day
2/16/2011
 5  common migraine felt a little dizzy and sleepy only the first time I took it. I had been having headaches that had been slowly intensifying over a 3 or 4 year period. At some point about a year ago I decided that I just didn't want to deal with it anymore. I never got aura, just twinging pain on one side of head turning into fairly intense kind of pressure and pain everywhere in head. Also got nausea, although no throwing up. Over the counter pills were useless, finally tried imitrex and bingo! Headache gone in an hour or two. What a relief. Lately it seems like I get the headaches a little more often, hope I'm not getting rebound headache, now I try to just take them when I'm feeling one coming on, probably about two pills in 2-3 days. M 32 1 years
50 mg 1X day
2/14/2011
 5  migraines related to IgG therapy Heavy limbs, mild sleepiness, NO narcotic "high" (which I see as a good thing). I had never had a migraine until I had my first IgG infusion at the age of 30. The day after my first infusion, I honestly thought I must be having an aneurysm, because the pain in my head was so intense. They gave me IV demerol, which put me to sleep, but when I woke up the pain was still there. After TWO DAYS of this pain (and VERY LITTLE sleep), an ER doc finally gave me Imitrex, and it worked wonders! Now I know that every infusion will give me a migraine, and as soon as I feel the first twinge, I take a 50 mg Imitrex and *poof*! All better! F 30 4 months
50 mg 1X AN
2/4/2011
 1  To alleviate migraine pain Currently, sumatriptan does not relieve the pain. The pain remains the same, and sometimes, more often than not, migraine intensifies, esp., if I'm not resting. I would not recommend Imitrex if you are sensitive to serotonin-active medications, which Imitrex happens to be one of this class. It supposedly inhibits break-down of 5HT, one of many serotonin neurotransmitters in the brain. It's pharamaceutical objective is vasoconstriction on specific vessels that dilate causing migraine via inhibiting reuptake of 5HT. F 43 45 days
5mg NS 6X O
1/21/2011
 2  Misdiagnosed migraine (I had an injection, not a pill.) Burning in injection site when I was first injected, burning and pressure in head, stiff neck, head felt heavy, pressure in ears, irritated throat, very subtle taste in mouth, tight jaw, felt dizzy and weak, moderate nausea (no vomiting), hot flashes. **Just because I had this reaction doesn't mean YOU will. You shouldn't always listen to everyone on here either, quite a few are hypochondriacs and overreact.**
I've been having headaches for about a week straight and when I finally went to the doctor he tried the Imitrex injection. After literally no more than two minutes, I felt a rushing feeling in my head (like fluid was flowing in) and my head burned, my neck felt very stiff and sore, etc (see side effects). All of the side effects were very sudden and pretty severe for the first 40 minutes, then it finally started to slowly let up. A few hours later, the feeling was almost completely gone. I did NOT have a migraine, however, so that may be the reason I had these side effects.
**Although the side effects were unpleasant, I'm not discouraging this drug. It can help some people but not all. Just take precaution and realize that some drugs are for everyone.**
F 19 1 times
n/a 1X O
1/16/2011
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 5  migraine Cool feeling in my limbs, somewhat lethargic the next day. I initially thought I had sinus headaches. The the pain was unilateral but my face (sinus area) hurt so badly that I thought that must be the problem. The Doctor convinced me to try this med after a night of vomiting and pain. I cannot believe I struggled through this pain for so long. This is a miracle for me! Have used it 3 times this month with amazing results. F 43 1 months
50 MG 1X AN
1/9/2011
 5  severe migraines with nausea No side effects of any kind. This drug is a miracle for me. About 30 minutes after taking the pill or nasal spray, my pain just slowly goes away. I do not have to use it very often, but I am so grateful to have it. F 50 5 years
50 mg 1X AN
12/17/2010
 5  Migraines No side effects at all. I have suffered from debilitating migraines since the age of 9. Ended up in the ER when I was 28, because I couldn't keep my Vicodin pills down. On that day, I had intractible vomiting and aura with migraine. ER Dr. prescribed Imitrex Nasal Spray, 20 MG. But the pill is a bit less expensive, and my migraines are well managed on the Imitrex 50 MG pill. Imitrex gave me my life back, and I will be forever grateful. F 41 12 years
50 MG pill 1X AN
12/4/2010
 5  Horrible migraines (family history) Great for years, but now worried :( Soon after the injection came out in the '90s my doctor wanted me to try it (in my 30s then) I went to the office and he did the injection & kept me there for an hour or so to watch. I remember feeling warm and a light pressure, and "flowing" toward my head, and after a while the pain went away. I Felt a little out of it and loopy. Used the injection on a regular basis - life changing - a 24 - 48 hour migraine was reduced to 2 - 4 hours of resting after imitrex injection. Sometimes the headache would not respond to the sumatriptan, so i would go to the family doctor and get a shot of demerol and try to sleep it off. When the pills started coming out would use them, depended on the severity of hte migraine - injection always worked best, but hated doing it, so would try pills if mild migraine. If instantly severe migraine or one when waking, would always do the injection. Over the years, also tried maxalt (didnt work as well as Worked great for years but now worried about contraindications with heart at age of 45...working with multiple doctors F 45 18 years
25, 100 2X M
11/25/2010
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 1  migraines Do NOT take this drug. I had 3 heart attacks as a result of this medication. The last just 3 weeks ago and at 42 years of age, ended up with a double bi-pass! I had absolutely NO other risk factors for a heart attack. I hadn't taken it for 2 1/2 years but the damage was done when I did take it. It caused cardio vaso spasms, which cause a heart attack. Try Naproxen and compuzine combo instead. I almost died because of Imitrex. F 42
6X M
11/22/2010
 1  blinding migraines none. It did not even touch the head ache...in other words...IT DIDN'T WORK! Didn't work for me. F 30 1 days
40 mg 2X AN
11/21/2010
 1  Migraines Extreme withdrawal, heart palpitations, anxiety, panic attacks, dizzy, vertigo, panic disorder, depression, nausea, fears, hard to breathe, cant concentrate, hard to focus. Worst drug ever. I regret it. F 22 6 years
6m 1X day
11/15/2010
 1  migraines constant muscle spasms in neck, shoulder, upper back, all on one side and facial spasms on same side. Apparently, triptans can cause neurological issues such as dystonia and spasms (see the package insert Zomig side effects). I also took Zomig for 6 months after Imitrex stopped working (rebound headaches). After seeing many doctors and reviewing literature on the subject, I am convinced that triptans caused the "movement disorder" I now have. I will never take triptans again. F 42 8 years
8X M
11/3/2010
 5  Migraines Sweating, feeling like coming down with flu like symptom but when I felt this I could also feel the migraine pain disipating. So when I felt the sweating/flu like symptoms I knew my headache was going away...YEAH! I could tolerate that sweating/coming down with flu like symptom for an hour unlike having a severe pain in your head, nausea, sick to your stomach feeling for 24 to 48 hrs. Prior to Imitrex my migraine sypmtoms were a constant for at least 4 times a month and always on the weekend! Prior to Imitrex being developed, having a Migraine made you wish you could die. However, taking an Imitrex tab right away plus an Anacin tab (and only Anacin) my headaches would be gone within an hour. If I waited too long before taking the Imitrex (couple of hours into the headache) I would need to take two tabs for it to work (along with Anacin). If the Imitrex doesn't work right away for you (and you didn't wait); then you probably do not have a migraine. You need to take Imitrex right when you know you are getting a migraine so DO NOT WAIT thinking the pain will go away, it won't! (I haven't tried the other migraine medicines because this worked for me...so why should I try something that may or may not work or even make me sicker?) P.S. Into menopause now and I rarely get a migraine,YEAH!!!! F 55 6 years
25mg 1X day
11/2/2010
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 1  Migranes I have been taking Imitrex for two years without any significant side effects. In the last two months I have taken the generic form (Dr. Reddy's) twice. Both times, 48 hours after taking the drug, I had blood in my urine and was treated for a urinary tract infection. Antibiotics cleared it up within 24 hours. The doctor does not think it is related to the Imitrex but I think it is too much of a coincidence that it happened both times after taking the generic form. Has anyone else experienced this side effect? F 57 2 years
100MG 1X day
10/15/2010
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 5  headache none really just makes me sleepy which is good. try it i cant live with out it, pills do not work for me the shot is easy and works with in seconds. F 54 12 months
30mg 1X W
10/4/2010
 5  Aborting Migraines The Pill Version - Heavy feeling in limbs, sweaty, shaky, felt like I was going to die. The Injection - None The pill was rather harsh for me. It would get rid of my migraine, but only after 2-3 hrs of suffering horrible side effects. I started using the injection to see if would help and I absolutely love it!! The migraine is gone in 30 minutes or less and I have minimal side effects. I am so thankful for the injections, otherwise I would suffer. F 25 2 years
6 mg 1X day
9/27/2010
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 1  Severe Migraine I've been taking Imitrex for years. I have never felt as bad as I did yesterday. I experienced INTENSE pain. I took one dose and waited. The pain was still there, I took the 2nd dose 2 hours later, the pain intensified, much more than what I began with. I thought my head was going to explode. I had to stand, hoping to slow down the blood flow. I was waiting for my husband to come home to take me to ER. I tried deep breathing and having my shoulders, neck, head, and forehead massaged with bio freeze and finally it subsided after approximately 25 minutes, not soon enough though I was in tears from the pain. After that, I couldn't lay down. Changing my body position made it worse again. I sat for at least 45 minutes, then tried again. I had to lay with many pillows to support my back and slowly make my way to a comfortable position. I had to take a xanax to stay calm and ease myself to sleep. The next day, I woke up and it was gone. I went to the chiropracter and was adjusted. I w Imitrex was prescribed to me for migraines related to menses. It worked well for a while. I feel it has lost its effectiveness on me. My doctor tried Frova with me. That did absolutely nothing for me. I think it's time to go back to fioricet. The old meds are still good meds. F 40 7 years
100mg 1X AN
9/15/2010
 5  migraines head squeezing, strange feeling that passes in about 15-30 minutes...along with the migraine disappearing. I love imitrex. I have seen many comments on people being surprised by the side effects. Well, you know when you get a prescription and a piece of paper comes with the drug in the bag the pharmacist gives you? READ it. It always lists all possible known side effects. Keep a file with that information. Also...always as your pharmacist about possible side effects when you get a new drug. It is YOUR responsibility to maintain knowledge of drugs you are taking. No one else's. F 36 10 years
6 mg inj 1X AN
9/10/2010

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