ANAFRANIL Reviews (CLOMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.7 (133 Ratings)

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 ANTIDEPRESSANTS CNS, MISCELLANEOUS

 Type: Rx Drug

  

ANAFRANIL  (CLOMIPRAMINE HYDROCHLORIDE):  Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living. This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ANAFRANIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ANAFRANILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  anxiety ocd Sleepy I found it really didn't do anything at all good or bad. Not sure if I needed to up the dose and stay on it longer. Could others please include the dosage they were on for ocd purposes. F 32 2 weeks
50 MG
12/2/2015
Email
 1  anxiety and depression Shaky worse anxiety sick feeling crying all the time no relief. Dear God I need some relief from this medicine if my Dr. will not take me off I going to take my self off couldn't feel any worst from withdrawal. I took this back in 1990's the Generic doesn't come close to the original. This is working in reverse of what it did at that time. Thanks drug companies always looking for ways to make money and don't really care about the patients. If you did you make it affordable and make back to the original. F 64 35 days
100 1X day
12/7/2015
Email
 1  OCD an Depressin Dry mouth, insomnia, pains in joints, burping, terribe constipation, increased depression I did note a slight decrease in my OCD within a day or two, but the side effects such as insomnia made me feel worse and overall I got more depressed. I would rather have my OCD than put up with the terrible side effects. Celexa 20mg controls my depression well, by the way. F 49 5 days
50mg 1X day
8/6/2017
 1  OCD phobias and panic disorder I wanted to revise my previous comments.I took this for almost 3 months and got worse on it,manic,racing thoughts,shaking,worsening of my OCD and anxiety.This durg worked for me for 6 years,but doesnt anymore.I pray I never have to take another antidepressant of any kind,they have all be horrible.I will stick to my Ativan and my therapy,but most of all will stop this madness on my own.Hope you all have better results than I did this time around. F 44 90 days
8/22/2009
 5  OCD Difficulty getting to an orgasm. It has helped the OCD to a great deal. I've tried replacing it with Prozac, it didn't work at all. I switched back to Chlomipramine (Anafranil) again. 12 years
6/26/2007
 5  Depression, Anxiety, Obsessions Dry Mouth, Sweatiness, Longer time till orgasm Within a week this medicine has near completely erased my depression, panic, anxiety and mild OCD. Each day gets better and I havent even made it up to 50 mg's yet. So much better than SSRI's and with fewer side effects - plus it doesnt numb you into hapiness, just amplifies everything good about life! 22 2 weeks
1/29/2008
Email
 4  Severe OCD Increased thirst, orgasmic dysfunction, orthostatic hypotension, constipation Was on 80mg of Prozac for 25 years and basically OCD symptom-free. Prozac stopped working and was put on 200mg Luvox. Helped a lot with OCD but made me so tired I fell asleep briefly behind the wheel once. Now on max dose of Anafranil for OCD (250mg). It’s lights out for OCD but with really annoying side effects. It’s only been three months but I am thinking of going back to an SSRI like Zoloft and see if that helps with fewer side effects. If not, I’ll probably be on Clomipramime for life. It’s all about trade-offs since no med is perfect I think. 49 3 days
250mg
3/23/2020
 3  Anxiety Blood pressure fluctuation 70 3 days
25
4/7/2020
Email
 3  
3/1/2006
 3  
12/26/2001
 3  
1/21/2005
 2  Ocd Terrible heartburn, brain fog and nausea. Rather live with Ocd than take anymore of this evil medication 58 4 weeks
25 1X day
1/8/2022
Email
 1  
12/4/2008

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