ANAFRANIL Reviews (CLOMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.7 (133 Ratings)

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 ANTIDEPRESSANTS CNS, MISCELLANEOUS

 Type: Rx Drug

  

ANAFRANIL  (CLOMIPRAMINE HYDROCHLORIDE):  Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living. This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ANAFRANIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ANAFRANILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  ocd dry mouth,constipation,priapism,weight gain,sleeping too much,mania,heart attack,agitation horrible drug. do not take this chemical. M 30 2 years
150 mg 1X day
10/22/2010
 1  OCD-DEPRESSION-PANIC ATTACKS Hallucinations ( visual-auditory and tactile ), insomnia, extreme hot flashes and sweating,very dry mouth, weight gain. After taking Anafranil for only 4 days, I immediately noticed that my depression was getting better, but my OCD got a lot worse and Icouldn't sleep. I would see shadows running on the floor like rats, seeing people that had twisted bodies, dogs etc...hearing people talking about me saying that I had to slap people and if I didn't do it, they would bite me or scratch me. I basically developed all the symptoms of schizophrenia. I didn't do anything right away because I just thought it was real and accepted it. Then people at work noticed and told me that I was staring at things and talking alone. I called my psychiatrist and he immidiately discontinued the treatment, even if it helped my depression. I am now taking Effexor XR 75 mg/day and it is working great ! M 32 2 months
75 MG 1X day
9/20/2012
Email
 1  depression DRYNESS IN THE MOUTH DIZZINESS M 34 1 years
9/12/2003
 1  OCD, Depression I was shocked. This was supposed to be the perfect med for me. It had worked for a relative with OCD. Moreover, the fact that I had comorbid depression and anxiety seemed to imply that it would be a great fit. In addition, the med was rated very highly by a lot of other people. Surprisingly, the med made me more anxious, irritated my nervous system to the point of making me feel like I was jumping out of my skin. It also did nothing to improve my poor appetite and intense fear of the future. M 34 6 weeks
12/12/2007
 1  depressipn Weight gain,comtsipation,sweating,sex problem,excessive sleepy, Above effects occurs when i was using clomoprill for 3 years.but i have still side effects like weight gain and excessive sleep. Was doctor suggest rightly ,such long course for boy of 17 M 20 3 years
150
7/14/2015
Email
 1  Tinnitus Nausea, myoclonus, hypothermia, insomnia, anal itching. I have been suffering from a low pitch tinnitus in my right ear for the past 4 years and have tried numerous drugs without much success. I thought I'd give this one a try after reading that tricyclic antidepressants have helped some people get rid of their tinnitus. Well, in my case we'll never know. The side effects were so bad (esp. the nausea, insomnia and hypothermia) that I gave up after only 4 days. The tinnitus bothers me, the Anafranil however made me really sick. You do feel high on this drug though so there's definitely an antidepressant effect there, hidden beneath all the nasty side effects. M 42 4 days
25 MG 1X day
11/24/2015
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 1  Depression and anxiety, thougts Suicide attempts. Aggressive. Teeth pain. Erratic behaviour. Memory loss Tried once before years ago and worked on a low dose, tried again and not helped at all. Still in a state of unreality and another psychiatrist took me off 200mg.He stated he would like me on 10/30max or not at all. I've since had propranolol but I've ceased all meds for time being. Currently got the and social anxiety. No purpose M 37 34 months
200
6/28/2017
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 1  OCD Nausea, heart palpations, vision, sickness, dizzy, blood issues, Took for one day insomia bad sickness to avoid this crap mellows you out but has sides M 24 1 days
25 MG
12/21/2015
 1  Premature ejaculation ( v dangerous) I took anafranil I start shivering and feel nusea after 3 hours I got massive heart attack I fell down broke my jaw, I admitted in hospital for 5 day they put stents, I was about to die, please ban this medicine .Thank you Please don't sell this medicine. If any death occur management is responsible for that. M 51 4 days
10mg 1X day
10/7/2023
 1  ocd Extreme insomnia,Excessive thirst, M 28 2 days
25 1X day
8/17/2019
 5  OCD and anxiety Flushing They changed my life enabling me to live with OCD pure O I dread to think how I would have managed without them. F 62 40 years
25 MG 1X day
11/21/2020
 5  OCD Side effects were gone within the first couple of week. The only annoying is constipation. Much calmer and happier overall. It didn't remove OCD thoughts, but definitely helped with panic reactions and anxious behaviour. F 34 2 days
75 mg 1X day
11/17/2020
 5  Extreme Anxiety, OCD Brain Zapping on and off. Extremely sensitive skin unable to sunbathe burn very easily even when using high factor sun cream. Life changing! Had many problems with SSRIs over the past 10 years I was allergic to everything but Anafranil along side Lamotrigine is a game changer for me and my family. I am much better person and feel so much better than ever before. F 39 2 years
50 MG
5/28/2020
 5  Obsessive-Compulsive Disorder Depression, fatigue, tiredness I've tried just about every SSRI available and nothing has ever subsided by OCD the way Anafranil does. I would go as far to call this medication a life-saver. If you're willing to brace some bad depression for the first two months or so of taking it, the effects are very much worth it. F 16 1.5 years
125 MG 1X day
5/26/2020
 5  OCD anxiety depression Nil except a little drowsiness first couple of days I am stunned at how effective this is for me. I am taking it in conjunction with Quetiapine. I have taken many other antidepressants but nothing has touched the anxiety which feeds the OCD until I started this. In one week my stomach has completely unknotted, I am stable and happy and my compulsions are coming under control. I could not be more happy so far. F 54 7 days
75mg 1X day
9/15/2014
 5  ocd, anxiety, bulimia nausea, acid reflux if I don't eat right after taking it The only med out of 6 or 7 antidepressants I tried for my anxiety/ocd/eating disorder. I take dramamine for if I'm not the driver in the car. I feel SO much better than I have since I was 7 years old. My bulimia is totally gone. F 29 2 years
150 1X day
1/13/2016
 5  OCD and Depression Extreme dry eye, short term memory probs CURED the OCD I have had since I was 8! Helping depression as well. Better sex drive. More creative. Much happier. I have schizoaffective disorder as well, and controlling the OCD is lessening my psychosis. F 35 5 weeks
50-75 1X day
1/16/2014
 5  BPD; depression; ocd spontaneous, tic like, random movement of my muscles (extremities); "busy mind" when I sleep - wake up feeling refreshed but not enough sleep (like I will wake after just a couple hrs of sleep); agitation in the manner of nervousness/restlessness, not anger like agitation. Of all the meds I have ever taken for depression this one seems to help me the most, but now after 1 1/2 months I am starting to get side effects F 46 7 weeks
6/21/2009
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 5  OCD Anxiety Disorder I took this drug over 10 years ago for 6 years.It saved my life.I have had horrible phobias since I was 5.It took all of that away.I stopped due to the incredible weight gain and profuse sweating.Now I find myself in really bad shape from phobias again and have gone back on it.The side effects I have now are in the morning, dry mouth,slight dizziness,shaking/tremors,hot flushes all over my body.Im on 25 mgs now and am going to bump up to 50 soon.It has already helped some and I've only been on it 2 weeks.If you can get past the side effects,it is the most effective drug for OCD. Does anyone else have excessive thirst or bad taste in their mouth from this? F 44 2 weeks
7/24/2009
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 5  OCD/depression constipation, weird dreams, difficulty losing weight I rather be overweight and happy than thin and miserable. Really helped with both depression and obsessive thoughts, F 56 2 years
9/24/2009

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