ANAFRANIL Reviews (CLOMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.7 (133 Ratings)

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 ANTIDEPRESSANTS CNS, MISCELLANEOUS

 Type: Rx Drug

  

ANAFRANIL  (CLOMIPRAMINE HYDROCHLORIDE):  Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living. This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ANAFRANIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ANAFRANILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  OCD I was started on 50MG and was supposed to titrate up to 150MG by week 3. I am still on the 50MG because these side effects wont go away. • Reduced mental focus • Confusion • Zoned out or auto pilot feeling • Lack of visual focus especially in far sighted vision • Dizziness • Increased forgetfulness • Reduced limb sensibility especially in hands • Reduced sex drive • Inability to get or maintain erection • Unable to ejaculate Although I did get the results listed below I would not recommend this drug. • Reduced Irritability • Slight ability to control “obsessive” or “fearful” thoughts during compulsive behavior. • Slight ability to control minor compulsive behaviors. M 26 17 days
50MG 1X day
2/21/2012
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 5  anxiety, depression, OCB, phobias constipation, non existent sex drive, sleepiness, memory loss problems, weight gain. Have tried so many other medications that didn't help at all and anafranil has taken away all mental issues. Was on 125mg and now on 50. Benefits far outweigh side affects!!!! F 27 6 years
5/15/2006
 5  OCD Dry mouth, constipation for a couple weeks, lower libido Anafranil has worked the best of all the SRI's I have tried for OCD. I have tried Zoloft, Cymbalta, Lexapro and none made much of a difference, Anafranil is in its own league, it was night and day better than any other med I have tried. The dry mouth is the only real side effect that still bugs me along with occasional night sweats especially on my legs which is funky. Libido is lower and orgasm is more difficult but that isn't all bad! M 27 4 months
4/12/2008
 5  panic, ocd, depression, GAD constipation best medicine i have ever been on F 27 1 weeks
8/14/2007
 4  OCD, Anxiety & Aggression Constantly having dry mouth, confusion, increased urination, feeling tired most of the time, loss of apetiate sometimes would be light headed, headaches it did help me in the OCD matter, I would say about 60% its gone. regarding agression I would say I still have it and currently taking Xanx for such problems.. This drug is good and bad at the same time, for higher doses I won't suggest it because I was on 150 MG per day and made my life a living hell for 10 days had severe constipation, sweeting, excesive urination, feeling tired all the time and of course lower sex drive!! is it worth it to go for high doses ..NO. M 27 4 months
50 MG 1X day
1/27/2011
 5  Ocd, depression, anxiety No side effects Most effective medication for me M 28 1 years
250-300 mg 1X day
5/26/2021
 1  ocd Extreme insomnia,Excessive thirst, M 28 2 days
25 1X day
8/17/2019
 5  ocd, anxiety, bulimia nausea, acid reflux if I don't eat right after taking it The only med out of 6 or 7 antidepressants I tried for my anxiety/ocd/eating disorder. I take dramamine for if I'm not the driver in the car. I feel SO much better than I have since I was 7 years old. My bulimia is totally gone. F 29 2 years
150 1X day
1/13/2016
 5  OCD, anxiety, depression difficulty urinating, constipation, dry mouth, decreased libido, difficulty ejaculating, sleepiness Highly effective drug but with many bothersome side effects and a really nasty withdrawal. I would certainly reccomend it to anyone whose symptoms are severe and wants to be relieved no matter the price. M 29 8 months
1/27/2009
 4  OCD Constipation, lower sex drive. Made my life better M 29 5 years
2/25/2005
 5  OCD I enjoy taking it since I know why I take it and that it alleviates my bad habits!! SMILE Plus I am not addicted to it - as like other drugs that I have taken for other issues. I would recommend it for the correct diagnosis! When I first began taking it - I did notice a start of a little rash on my arm - however it has subsided! F 30 4 years
9/21/2007
 4  OCD,panic,GAD,Mjr depresion,moods dry mouth, spaced out, decreased sex drive. Feeling sleepy and zombified. Fatigued, numb, frequent UTIs, constipation, tremors, feeling of not being myself. Have tried just about every other medication and nothing helped. This actually works. Sometimes i find the side effects are a bit too much to deal with but would rather have them than my original problems. Don't know what i would have done without anafranil. It saved my life. F 30 10 years
2/3/2009
 3  OCD and depression Dry mouth, Dizziness when standing up, nausea, diarhoea, constipation, drowsiness, twitching muscles and hands, indigestion- this drug is quite acidic, edgy feelings after being on it a while, increases anxiety and skipped heartbeats, fatigue for first few weeks- wears off. Upon forgetting to take it I had nasty side effects, i sweated profusely, shortness of breath, frequent toileting, alerted feeling, a little panicky at times from the high temperature. I find this particularly nasty, the physical addiction our body goes into. I think Anafranil is good for anyone with acute anxiety condition or panick disorder like me. Panic disorders can be hard to treat, but not impossible, it can be gotten rid of for long periods thank God. But its a strong drug even at 225mg a day, forgetting to take it for 3 days i thught i had a stomach bug and flu. I was throwing up and toileteing frequently. I feel these drugs are good for as long as you need to take them and no longer. I feel that with prolonged use side effects would increase. I really dont like the edgy feelings ive been getting with cramps in my gut. I certainly hope toc hange it and recieve therapy from a HSE in crises. F 30 9 months
3/2/2009
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 3  Severe depression, anxiety Rapid weight gain, doped up feeling, insomnia at night, sleepiness during the day (even when taken at night), no sex drive, etc. It seemed to lift my depression, but am considering getting off of it due to the weight gain. :( F 30 2 weeks
150mg 1X day
10/3/2010
 3  ocd constipation , bloating,muscle pains,breast enlargment,diffuculy urination,fatigue and in high doses dry mouth and excessive sweating to me it doesnt work in high doses and made ocd symptoms more severe be careful with the dose very low doses may benifit you and higher make ocd severe.talk with your doctor.i used to take it in 150 mg but after many years i take fluoxetine and low doses of anafranil. M 30 10 years
18,75 mg 1X day
7/20/2012
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 1  ocd dry mouth,constipation,priapism,weight gain,sleeping too much,mania,heart attack,agitation horrible drug. do not take this chemical. M 30 2 years
150 mg 1X day
10/22/2010
 5  yes i gained alot of weight(about60lbs), slept alot 10-12hrs a day and had to take naps, blurry vision, i had no physical motivation and always felt lazy, dizzy spells, no sex drive or intrest in sex, sweated alot F 31 5 days
4/30/2006
 5  depression weight gain, sleepiness It changed my life, now I´m a happy person again. It is the best medicine by far. M 31 5 years
1/4/2010
 5  OCD Loss of interest in sex, inorgasmia, impotence Lifesaver for keeping OCD at bay, also stops my insomnia and allows me to wake up at a normal time without feeling groggy all day which I cannot do otherwise. Great feeling of being at peace. M 31 15 years
100mg 1X day
12/27/2013
 4  Trichotillomania I don't remember any minor side effects, but I had a real problem with mental confusion, to the point that I stopped this medicine even though it was working. It was like functioning on 3 hours sleep - my short term memory was shot and I had trouble recalling passwords and facts. This drug is amazing for OCD and trichotillomania. I took a pill and within minutes had zero desire to pull. I stopped taking it because I couldn't tolerate the mental confusion but I'm not sure if it it is a brief side effect that gets better over time or not. I plan on trying it again soon because I need the help. F 31 2 weeks
3/15/2009

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