Reviews for PRILOSEC228 ratings: (side effects include depression sadness)Edit Filter | Clear FilterCompare PRILOSEC with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on PRILOSEC: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR PRILOSEC | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Gastritis | Extreme nausea, stabbing stomach pains, life-altering anxiety and depression, weight loss, no appetite, insomnia, heartburn. | Worst experience of my life. This pill should be illegal! I was prescribed omeperazole after getting gastritis. After about 2.5 weeks on the medication, I began to go severely downhill. Insane nausea, stomach pains, that would not cease. I also started getting very intense anxiety and would pace my house literally all day and night, trembling. I still didn't know it was the omeperazole! Went to my GI, had every blood and stool test imaginable done, had an upper endoscopy done which revealed a perfectly fine stomach, had ultrasounds of all my organs done, etc. Everything came back fine. But I was going downhill and fast. In a matter of 6 days, I lost 14 pounds. Then something clicked and I thought about the only common denominator: omeperazole. I went online and realized I wasn't alone; so many people have experienced the same symptoms: nausea, stabbing pain, weight loss, insane anxiety and depression, etc. I went off cold turkey that day, even though they say doing so in that fashion can be dangerous due to rebound effects. I immediately started feeling better. The nausea, stabbing pain, etc., went away! The anxiety has been slower, but I'm getting better every day. It's been about 4 weeks since I stopped the awful medication, and I am almost back to normal. The anxiety has taken some mental work to get through but you can do it! Do not take this medication! And if you have and have experienced these | F | 36 | 4 weeks 40MG 1X day | 4/22/2023 | 1 | Reflux | Anxiety and depression. Very dry eyes. Brittle nails. | Depression and anxiety have increased. My eyes are burning in the night no matter how much eye gel I use. I feel like I'm in a dark emotionless hole. | F | 69 | 30 days 20 mg 1X day | 1/22/2023 | 1 | GERD/Hiatal Hernia | Severe Anxiety/depression, panic attacks, shortness of breath, loss of appetite, stomach pain, muscle fatigue, nausea, chills, sweating, clammy hands/feet, bad taste in mouth | I have been healthy and happy my whole life. I was diagnosed with GERD and a Hiatal Hernia (runs in my family). I was prescribed 40mg of omeprazole a day for life. I took it for 2 months and everything was great, my symptoms were gone and I had no side effects. I was off of it for a few days without withdrawal symptoms because I went on vacation and forgot my meds. I came back and started taking it again. 2 days into taking them I was just standing around and I had a horrific panic attack out of nowhere. I almost passed out about 5 times in the span of an hour, I had chills, I was shaking, I could barely breathe, my heart was racing. So naturally I went to the ER. All of my tests came back perfect. I then talked to my uncle (who is a doctor) and he told me it's just anxiety, and that I must be stressed about something in my life. The only thing is that I'm happier than I've ever been at this stage in my life, and ive never even had anxiety or depression. Theres no way that 2 days into taking the meds again, I feel these side effects without them being correlated. Every doctor ive spoken to has said that omeprazole doesnt cause side effects. This pisses me off because I know my body better than anybody else, a PhD doesnt make you god. I stopped taking the meds a few days ago and have started taking B12, magnesium and 5htp supplements to combat the sever anxiety that I'm feeling constantly. I've also decided to abandon prescriptions for my GERD and am trying to change my diet. | M | 25 | 2 months 40mg 1X day | 1/8/2023 | 1 | Silent reflux | High and severe anxiety, irrational fear, loss of appetite, nausea, shaking and jitters, throat tightness or lump in throat feeling, chest pains, severe panic attacks, racing heart, awaking from sleep with racing heart and anxiety, insomnia, hot flashes, cold shakes and sweats, lightheaded, feeling of doom or hopelessness, mood swings and extreme sadness. | F | 26 | 5 days 1X day | 1/24/2022 | 1 | Acid Reflux | Anxiety, Depression, Slight Vertigo, Hopelessness, Disassociation, Hot Flashes | Started with 20mg then moved up to 40mg did not like how it made me feel physically so moved back down to 20mg a day for the last few months. I noticed the last two to three months my anxiety and depression began to rise. I would lay in bed feeling lost or disassociated from my friends and family and I couldn't figure out why. I also had a sense of fear of things which was super odd, I've never dealt with anything that made you feel so fearful and lost. The few days before I quit taking Prilosec I would cry for no reason at all and was frustrated as to why I couldn't figure out what was making feel this way. I finally decided to google Prilosec and anxiety and was blown away by what I found. Stopped taking immediately and have been off for a week now but still have episodes of anxiety and hopelessness. Hoping things get better soon! | M | 41 | 9 months 20-40 mg 1X day | 10/11/2021 | 1 | GERD | Dizziness, headache, depression, anxiety. Foggy feeling disoriented. Nerve pain in hands and feet. Severe anxiety when I try to fall asleep. Jumping out of my sleep with a racing heart. | This medication should be taken off of the market ! I did not attribute some of my symptoms to the medicine while I was on it. When I got off of this medicine I experienced the WORST withdrawal symptoms. I felt like I was dying. I could barely sit up. I literally thought I was loosing my mind. Please aware of these possible side effects. | F | 29 | 6 months 40 MG 1X day | 10/7/2021 | 1 | Acid reflux | Anxiety/depression, sadness, feeling of hopelessness about life in general! rapid heart rate, jitters, not at all myself. | Stopped taking it four days ago when I realized it was causing these side effects, and I have started slowly getting back to normal each day. My doctor said it could take weeks. I highly recommend NOT taking this drug. | F | 60 | 16 days 40 mg 2X day | 9/16/2021 | 1 | heartburn | High anxiety, heart palpitations, shortness of breath, fatigue, depression, mental fog, insomnia, disassociation, loss of appetite | I had a bad reaction to Prilosec OTC. I took it in the mornings, before breakfast, for 7 days until I realized it is causing me issues. Starting around the 3rd day I began feeling more stressed and my heartrate was up to ~100 from 70, which is my normal resting heartrate. On the fourth day I had to drive for 2 hours and felt on the edge the whole time, pulse was 130. I recognized anxiety and set up a call with a psychiatrist to help me. I never had this before (or since). On the 7th day I realized that it might be the Prilosec, found others complaining and I stopped taking it immediately. The side effects took me around 2 months and a half to clear. The first 2-3 weeks were the worst, with many anxiety attacks and some depression. I also started waking up a lot at night, 7-10 times per night. The anxiety started to come and go, but took approx 8 weeks until I had the last attack. Insomnia took a bit longer to clear. I took vitamins (B complex, D), minerals (magnesium, calcium) and supplements (valerian root, pepsin HCl), pushed myself to exercise (run), but not really sure that these helped. Blood tests looked fine. My GP had another patient with same symptoms at the same time as me, but never heard of such effects before. There are recent studies that indicate a link (search for "Elevated anxiety, hypoactivity, memory deficits, decreases of brain serotonin and 5-HT-1A receptors expression in rats treated with omeprazole"), but unfortunately no actionable remedy/suggestion | M | 34 | 7 days 20 1X day | 4/21/2021 | 1 | Silent reflux | Panic attacks, depression, no libido, numbness and tingling, increased hunger, brain fog, tinnitus, gas, vertigo, dizziness, hip pain, back pain | I've been off Prilosec since the end of December- most of the side effects thankfully wore off with the help of vitamins and probiotics. I had these terrible side effects linger for around 2-3 weeks when I stopped taking the medication. It seems like Prilosec gave me additional problems. I actually have heartburn now- before I just had silent reflux. Also, I'm constantly burping now, suspect this evil medication might have given me SIBO. My symptoms were actually worse after I stopped taking it- it must have still been in my system. If anyone has any advice, or wants to chat please email me. | F | 19 | 14 days 20 mg 1X day | 3/23/2021 | 1 | Heartburn | High anxiety and depression. Brain fog and disassociation with reality. Muscle fatigue and shakiness | I had no idea a ppi could make you feel this way. I hope since I only took it for a short while that these symptoms subside. I can’t work. I can barely eat. It’s awful. Please tell me this goes away. | M | 34 | 9 days 20mg 1X day | 3/15/2021 | 1 | Silent reflux | Hip pain, tingling in hands and feet, anxiety, depression, brain fog, racing thoughts, gas, stomach pain, increased hunger, vertigo, blurry vision, tinnitus, insomnia | I've been off Prilosec since the end of December- most of the side effects thankfully wore off with the help of vitamins and probiotics. I had these terrible side effects linger for around 2-3 weeks when I stopped taking the medication. It seems like Prilosec gave me additional problems. I actually have heartburn now- before I just had silent reflux. Also, I'm constantly burping now, suspect this evil medication might have given me SIBO. My symptoms were actually worse after I stopped taking it- it must have still been in my system. If anyone has any advice, or wants to chat please email me. | F | 18 | 14 days 20mg 1X day | 2/25/2021 | 1 | Gerd | Depression, anxiety, hot throat sinus infections, irritable everything bothered me. Doom and gloom, it seemed like my world was coming to an end.Constant coughing up phlegm kept me awake at nite. | Do not take I think it's some kind of poison. | F | 75 | 3 months 20mg 1X day | 12/15/2020 | 1 | Acid reflux | Severe depression, chronic fatigue, severe brain fog, frequent irritability/personality changes, anxiety/lower stress tolerance | I started experiencing some acid reflux symptoms around 2017, when I was 24. They got more frequent & severe over the next year and my doctor put me on Prilosec two years ago when I was 25. Over time, I started developing pretty life-changing side effects (had it happened right away, I would have made the connection and stopped it, but given the slow, but steady, onset, my doctor's assurances that it was completely safe, & my age being in the range when mental issues often manifest in younger men, I thought it might have been a dozen other things): An almost unceasing (and worsening) brain fog, a sudden problem with anxiety (particularly in social situations or when speaking to groups), regular and worsening depression, chronic fatigue so bad that I often couldn't stay out of bed long enough to do work and would regularly lose days in a totally unproductive haze, and extreme irritability. I stopped taking this about a month ago and while the negative effects haven't yet vanished, they feel like they've stopped getting *worse*, so I hope it's a matter of time before I'm my old self again. TL;DR: I'm stunned that this garbage made it through FDA testing and wouldn't recommend it to anyone who doesn't want to feel like a complete trainwreck of a person. I would honestly rather have just stuck | M | 27 | 2 years 40 1X day | 11/30/2020 | 1 | Upper GI Bleed/ Ulcer | Worst god damn drug. How do they even get this sh*t FDA approved. I was prescribed this after I had an upper GI bleed from an Ulcer. Literally from the day I took I started feeling dizzy.. Day 2, bouts of depression and crying, overwhelming anxiety and random pains in the stomach area. I couldn't sleep for the few nights I took this and when I could get an hour or so of sleep I would jolt myself awake. DO NOT TAKE THIS IF YOU CAN AT ALL AVOID IT. | M | 40 | 2 days 20mg 2X day | 11/18/2020 | 1 | Reflux asthma | severe depression, severe anxiety, panic, agitation, confusion, rapid thoughts, social nervousness, fatigue, feeling very cold, lump in throat, mild sore throat, increased stomach pain | My asthma doctor prescribed this to see if it'd lessen my need for my rescue inhaler from attacks I get after eating and I wish I wouldn't have touched this stuff. I already have depression and social anxiety and adhd-type symptoms, but have been relatively stable lately and all that changed 2 days into taking this. Wasn't sure at first if it was the medication until I started googling reviews. I've been feeling like I'm losing my mind. I haven't noticed a significant improvement in my ‘reflux' since I never have heartburn, though I haven't reached for inhaler daily like I was before. It's definitely not worth it and I'll just stick with my inhaler. Glad I got on here and read through some of these reviews so now I know it's not just me. It's crazy that a medication like Prilosec can cause so much emotional trouble for someone in four-days' time. | F | 29 | 4 days 20 1X day | 11/13/2020 | 2 | Stomach and throat ulcers, gerd | Unable to focus, slow memory recall, depression, feeling low, hopeless crying, anxiety, panic attacks, bad circulation in arms, tiredness, insomnia. Feeling of doom. Gas. | After about 2 months. And upper endoscopy it had almost completely healed my ulcers. Thats nice but have been off a few days and dont feel better yet. Im kinda scared i wont get back to normal. | F | 36 | 2 months 40-80 mg 2X day | 10/25/2020 | 1 | Acid Reflux | Anxiety, Insomnia, Depression, Heart Palpitations, Hot Flashes I found this site in search of comfort. I was looking for some clarity on how long people experienced the side effects. I was supposed to take for 30 days. Only took it for 20 days then started having anxiety and sleeplessness. I didn't link the 2 together I really stopped taking the MED b/c I was on it for throat irritation and felt like it had cleared up so I stopped. It just so happened it was around the same time the sides started. Let me first start by saying I am an excellent sleeper and can normally not even make it through a movie without falling asleep. I can usually take naps no problem and could sleep 10-12 hrs if I didn't have to get up. When I was on vacation all of a sudden I started waking up for no reason(this was about 20 days on the MED) 2-3 times a night. I would wake up feeling hot, and kind of in a panic and felt claustrophobic. I was usually able to get back to sleep. I attributed to not being in my | Some things I tried- Drinking Chamomile Tea before bed, melatonin, benydryl, magniesium, b12, b6, multivitamin, CBD oil On about the 2-3 week after stopping the MED I would still wake at night every 1-2 hrs. but would be able to go back asleep within 30 mins or so, I would still feel hot, the anxiety was lower but still intermittent. I was still not anywhere near my normal self but it was more tolerable as I could get some decent sleep and function the next day. Wk 4-6 I cont. to wake less freq. and would be able to get back to sleep within 10 mins. The anxiety was gone mostly After Wk 6 I felt like I was back to normal. I started sleeping through the night, could take nap during day, had no more waking up feeling hot, and no more anxiety. Also I have never had any sleep or anxiety problems ever in my life. I am not sure if any of the vitamins/ meds listed above helped decrease the amount of time to help me get back to myself or not. It could be that your body just needs time. I was willing to do about anything during the 2 worst weeks. I went to a sleep doctor (who just told me I had a sleep maintenance insomnia from anxiety). Anyways it looks like I am back to normal and hopefully no long term effects will be done. But this is a NASTY drug and I will never take again. I hope this helps someone in the future to give you hope that you will get back to normal with time. I had some long and miserable days of wondering if it would ever end. Best Wishes | M | 37 | 20 days 40mg 1X day | 10/14/2020 | 1 | Stomach Ulcer | Extreme fatigue, heaviness in arms chest, jolted out of sleep, anxiety, panic attacks ,tingling in legs, twitching, depression, hopelessness, lack of good emotions, crying, heart palpitations, | I am writing this for my husband, am so relieved to find this web site, I thought he was losing his mind so did he! His first symptons showed after 6mths of taking Omeprazole (UK) he was not given any advise on how long to take the meds, with tingling in legs, a visit to the Dr blood samples ruled out everything but a slight increase in iron levels. He then went through a whole array of side effects. He found taking valerium and magnesium helped with his night jolts, sleep and twitching in limbs . After 10 months he stopped taking his meds and things started to improve. Unfortunately after 2 months he had symptoms of ulcer and started taking omeprazole again. This time his side affects were instant! Hes weaning himself of the omeprazole and we are now looking at alternative solutions to manage his acid levels. It's strange and am angry that his Dr had not picked up on his side affects and prescribed an alternative med., all of this could have been avoided. I cant wait to get my husband back to his normal self, hes not the man he was, 2020 has been a living hell for him. | M | 57 | 10 months 20mg 2X day | 10/1/2020 | 1 | Suspected gastritis | Little to no libido, intrusive thoughts, brain fog, slight depression, insomnia, slight hallucinations, slight emotionless | I should've never took this medication. I do not feel like myself while currently taking this medication. It helps my stomach issue a little but the side effects make it not worth it. Before I started this medication my sex drive was hyper and had no problem getting turned on. Now Im having trouble getting aroused. Also I believe this medication is disrupting my emotions. A couple days ago I was telling my lover how much I was in love with them now I could barely feel anything to anyone. I can not wait to stop this medication and return back to myself!!!! | F | 25 | 1 months 20 1X day | 9/19/2020 | 1 | Ulcers and Gerd | Nausea, lightheaded ness, dizziness, anxiety, depression, tingling in left arm, grogginess, trouble concentrating, diarrhea, headache | Was told to take twice a day for two weeks and then once a day for two more weeks. I started feeling lightheaded and dizzy fairly early in the first week, and then halfway in to week two the nausea and diarrhea really kicked in. I stopped taking it about a day ago, but I'm still pretty nauseous and lightheaded. Really hoping the side effects go away soon. | F | 33 | 11 days 20 mg 2X day | 9/19/2020 |
PRILOSEC (OMEPRAZOLE): Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)