UNISOM Reviews (DOXYLAMINE SUCCINATE)

Average Rating: 2.5 (88 Ratings)

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 ANTIHISTAMINES

 Type: Over-the-counter Drug

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5


RATING  REASONSIDE EFFECTS FOR UNISOMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  insomnia It puts me into a very deep sleep. Bad tremor and shakes. Nothing else makes me sleep so deep. Some depression. I have taken many psychiatric drugs and Unisom works better for sleep. Overall good experience. M 43 2 years
25mg
11/20/2014
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 3  occasional restless nights Agitation/irritable, restlessness M 28 3 days
50
6/2/2014
 3  can't sleep fatigue, drowsiness, irritability, depression. the first night taking this pill, i overslept an hour, but still woke up drowsy, lazy, had a headache, dizzy, etc. took it again the same night and it took four hours to kick in. F 20 3 days
30 mg 1X day
4/24/2014
 2  Insomnia Sure, it put's you to sleep- not only for the night, but also for most of the next day I took 1- 25mg tab and it definitely put me to sleep, but I had bad side effects the next day. I was depersonalized, confused, unmotivated, emotionless, and didn't want to move. I drank 3 monster energy drinks- that barley helped me to get semi-motivated. I usually can't drink energy drinks, because I am so sensitive to caffeine. I also had crazy erotic dreams about Bill Clinton. Needless to say- I am done taking Unisom. F 28 1 days
25 1X day
4/9/2014
 3  Insomnia Sometimes it worked well for me, helping me fall and stay asleep for most of the night. Other times, however, I felt exhausted, spaced out and foggy the next day, and also suffered nausea on a few occasions. I also experienced bizarre, vivid dreams on a few occasions after taking this medication. Doxylamine succinate is supposed to be the most sedating over-the-counter medication available, so use caution when taking it. When taking this medication, make sure you avoid other sedating substances such as alcohol, benzodiazepines (e.g., Xanax, Klonopin), and prescription sleeping pills (Ambien, Restoril, etc.). Because of the potency of this medication, you may want to start out with a smaller dose—half a pill, say, which equals 12.5 MGs—to see how you react to it. M 54
25 MG 1X day
3/27/2014
 4  Insomnia First time I took it I experienced anhedonia, emotional blunting and fatigue. But I took whole 25 mg tablet. I realized I can induce sleep with as little as 7mg, which is roughly a third of the tablet. Any sedation is counteracted with caffeine next day. Nowadays I have to take the whole tablet though, I still get decent sleep though. But I always reacted poorly to benzos and other GABAenergic drugs. F 27 1 years
12.5-25mg
12/25/2013
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 2  Insomnia Leaves me depressed, depersonalized, headache and agitated, I'm moving on. F 47 6 days
25 mg
12/20/2013
 3  Insomnia Agitation, irritability, depression This drug worked well at getting me to go down, but I woke up several times during the night and the next day I would feel worthless, agitated, and depressed. All sleeping medicines cause this for me for some reason. I'm trying to go to sleep naturally now. This is just my experience, it may work fine for you. F 30 1 years
25 MG 1X day
8/9/2013
 1  I could not sleep I feel super lazy the next day and sad very sad I'm normally a very happy person but after of taking these pills I wanna quite life the next day M 32 2 days
Two pills
7/10/2013
 1  Insomnia I take this drug only occasionally and find that I am very agitated and depressed the next day. Also, get constipation. F 61 2 days
1X day
3/30/2013
 2  Insomnia I have been on ambien and was up to 30mg but it would still take 2-3the hrs to kick in. I have been using unisom when my ambien runs out bc im only allowed a certain amount each month. I am now up to 5-6a pills and they ztill take 2-3 hrs to fall asleep. I wish i could find a sleeping pill thatwould take 15-30the mins to work and still sleep through the night. With 6 pills i still wake up in the middle of the night and if i have to get up for work after only 3 hrs of sleep i dont feel groggy or anything. Im wide awake and can stay awake for 24 hrs no problem F 32 3 days
300
11/19/2012
 1  severe trouble falling asleep causes me not to be able to fall asleep more than if I did not take it! And then I sleep feeling like I'm wide awake. Worsens RLS symptoms. Compared to the now MIA Simply Sleep (by Tylenol) Unisom does not work at all. Save your $$ and just take deep breaths. F 40 14 days
50 1X day
9/12/2012
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 2  Insomnia This is my first (and last) time taking Unisom. I have frequent insomnia but do not usually take any medication for it. I have tried Ambien and Lunesta in the past with no bad side affects. Unlike Ambien, I had a very difficult time falling asleep, missed my morning Alarm clock, overslept by 40 minutes, and was so sleepy that I was unable to function for most of the day at my office. The sensation was like a really bad hangover. The effects started to wear off approximately 15 hours later. Multiple cups of tea and coffee did little to help the drowsy, cloudy feeling I felt all day. Worst sleep-aid I have ever used. Benadryl, Ambien, and Lunesa have little to no side-effect if taken once in a while. M 41 1 days
25mg 1X day
4/23/2012
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 4  trouble falling and staying asleep I never taking sleep meds so i started with 1/2 of one 25mg tablet after 30 mins of no results I took the other half. I still had trouble initially falling asleep but after that I was out, I had no problems with waking during the night. I won't take it again because I felt tired and groggy all the next day. Not worth it I would rather be tired from no sleep and able to function then feeling out of it all day because of a pill. It basically all depends on the past medical history. I someone has been taking sleeping pills often and have built up an immunity to them this probably won't work, but for someone using only once in awhile it does the trick. F 27 1 days
25
3/31/2012
 2  Insomnia Unison(doxylamine) is not as effective as I hoped. I have to take between 50 and 100mg (2-4name) pills)to feel sleepy at all and also add a couple benadryl if the unison does not work after a couple hours. I do not have insurance but I gotta find a cheap Dr. Because these otc pills are useless F 30 1 days
100mg
3/24/2012
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 4  To prevent insomnia None so far after taking them... It will work when I dissolve by drinking water along with the 5HTP. Remember that this does not promote a normal or rejuvenating sleep, it helps people to fall asleep. Once people take two which those that have the melting tablets, drinking water along with the 5HTP may or may not help. As a user, I'm satisfied with this. 5HTP is to relax the mood and with the Unisom, it will last a night and wake up with a little grogginess. I'm okay so far, so no side effects as of yet. I gave it a four out of five because this will not work without taking 5HTP twice a day. M 22 1.5 weeks
50 1X day
3/18/2012
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 1  Insomnia depression, anxiety, sleeplessness, dry mouth, hangover. Effects have been bad for me. Its my belief that after taking this drug for months that it has made my depression and anxiety much worse. I would not recommend using Unisom or other antihistamines over any period of time if you are predisposed to depression or anxiety. Like other hypnotics, sleeping pills alter brain chemistry the same way. Benzos, antihistamines, and SSRI's (antidepressants) target GABA receptors in the brain. Taking Unisom or other hypnotics will only mask the causes of insomnia, you will fall asleep, but it will be unnatural. This is what gives you that "hangover" effect when you wake up in the morning. That "hangover" effect may have cumulative negative effects on your brains normal operation and can, over time, make depression and anxiety worse. We know depression, anxiety, insomnia are all related. I know its tempting for doctors and patients to seek a quick resolution of insomnia or depression since they impact your life greatly. But I would caution against using Unisom or other sleep agents if you have depression/anxiety and seek practical, natural, and behavioral steps to alleviate your insomnia. There is very little information about doxylamine succinate. These drugs have only been around for a few years while insomnia, depression, and anxiety have been around for as long as human kind. We cannot fool ourselves into taking new drugs for ages old conditions. Unisom, Benzos, SSRIs, & antihistamines side effects are t M 26 2 years
25mg 1X day
2/17/2011
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 5  sleep aid First day wonderful rested and energized. F 59 3 days
50 mg 1X day
1/30/2011
 5  insomnia morning grogginess, difficulty waking, increased appetite in morning I became reliant on these tablets for sleeping so cut my dose to a quarter of a tablet and increased to half if still unable to sleep. Now I only use for emergencies. Very helpful! F 25 1 years
12.5 1X day
10/26/2010
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 5  Insomnia; to sleep Sometimes groggy in the morning. I usually take it when I know I don't have to get up early, and I let it put me back to sleep for a while. My seventeen year old daughter and I both have insomnia. For her, Unisom Sleepgels have worked very well. I have had to take something stronger most nights, and am currently taking Ambien. But on occasional nights, I do take the same Unisom Sleepgels that my daughter does. They work very well. Sometimes it takes a while for them to take effect, so I will take one an hour or so before bedtime. They often keep me very sleepy the next morning, so when I take them, I try not to plan too many morning activities. At the time they do put me to sleep, they feel very strong for an over the counter medication. F 49 2 years
1 Sleepgel 1X day
10/1/2010

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