SINEMET Reviews (LEVODOPA; CARBIDOPA)

Average Rating: 2.5 (87 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5


RATING  REASONSIDE EFFECTS FOR SINEMETCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Young Onset Parkinson's Brief stomach upset when taken in the morning. Dosing is tricky. Restless when taken too much; very evident when it wears off. Flatulence (yuck), daytime sleepiness, nighttime insomnia, and some memory issues. I started tremoring at age 27. I was diagnosed with essential tremor for a long time. My symptoms got progressively worse until it became difficult to function. After suggesting PD to my doctor for over a year, I finally got properly diagnosed. Sinemet has made my life so much better. I'd take the side effects over the inability to write, walk, and engage in normal life activities ANY DAY! F 35 4 months
7/2/2008
 4  Restless legs daytime fatigue I've been taking just 4 days, but so far it is a godsend. I was extremely sleep deprived 5 days ago from RLS. My ferritin level is low, so I am also taking iron therapy and the hope is that in a couple months my ferritin level will be up to 50 or 60 and I won't need the sinemet any more. (RLS is rare in people with ferritin levels of 50 or more.) I am on the lowest possible dose, so I don't take it before bed, I wait till the RLS kicks in, then get up and take the Sinemet. I am usually back to sleep in 30-60 minutes. One night I slept 10 hours and it was heavenly! F 51 4 days
4/13/2008
 1  suspected Parkinsons Dementia, COD, anorexia Please beware side effects M 75 7 days
1/27/2008
 1  Parkinsons Delusions, erratic behavior, disturbed dreams, memory loss, and insomnia. My father was on this drug for two years. He became increasingly delusional and we were told it was because his disease had progressed and that we should put him in a locked unit. After 4 hospitalizations one physician told us of the drugs side effects. We discontinued the drug. Dad is now back in his own home and doing well without assistance. Shaking is better than the suffering he went through. M 77 2 years
11/5/2007
 3  Restless legs Syndrome Brief night time hot flashes. Sinemet was great for two years - one pill before my bedtime did the trick. Then, RLS started during the day at work, and my night time doses had to be increased so that I could sleep. Now, I have to take one pill before bedtime, a second pill after three hours, and a third pill after three more hours. I am experiencing general insomnia - just cannot sleep well. F 54 2.5 years
4/25/2007
 2  Parkinsons Anxiety attacks, irregular heart rhythms, severe on-off effects with trembling and a feeling of having your stuffing knocked out , addictive, and forces the body to give up production of its own dopamine so that without it you have no mobility. Starts off promising, with light doses and pleasant results. However eventually you have to keep increasing the dosage to be able to function -then you pay for it with the side effects. A vicious outcome you would not wish on anyone. M 55 4 years
3/29/2007
 1  Parkinson's When it kicks in, I feel great, but after 2-3 hours it starts to wear off and I go crashing. I have what I can only describe as severe drug withdrawal symptoms. I get the worst butterflies in my stomach and I feel the need to keep moving because of the overwhelming crawling feeling in my legs. It's awful. This pretends to be the best medication for PD but it's actually the worst. There has to be a better solution. F 49 5 months
2/25/2007
 5  Restless Leg Syndrome Works wonders. After 2 years use, I now need two tablets instead of one, but no noticeable side effects. M 63 2 years
1/29/2007
 3  parkinsons terrible stomach discomfort and constipation as far as i'm concerned it does what is expected providing.relief of strong tremor and a somewhat sense of well being.However the accompaning stomach discomfort more than makes up for the good.Kindly respond if you've experienced the same discomfort. M 73 1.6 years
11/24/2006
 4  Frequent, severe muscle cramps Mild constant backache/night sweats Don't like the backache or the night sweats, but so far, this is the only thing that has helped alleviate most of the cramps I was getting in the muscles of my legs, feet, arms, and hands. F 57 10 months
11/15/2006
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 3  Parkinson's Disease Extension of fingers; cramping of fingers; headache; dizziness; tightness in shoulders. Tricky to dose; hard to distinguish the side effects from the disease it treats. When dosed properly, it's wonderful, making me able to be almost "cured." M 64 3 years
9/25/2006
 1  Left Side Dystonia PERMANENT FOREARM AND HAND TREMOR, WHAT A NIGHTMARE!!! DO NOT TAKE THIS DRUG! EVIL DRUG!!!!!!!!!!!!!!!!!!!! M 46 3 years
6/21/2006
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 4  PLMD after about a year, I have experienced heart palpitations\irregular heart beats M 47 1 years
6/3/2006
 3  PLMD Extra involuntary movements. Upset stomach. Extremely agitated sleep if also had caffiene or cold medicine. Neuro doc changed me to Mirapex because he said Sinemet should be saved for latter stages. If all other meds have ceased to work and Sinemet is the best choice, remember that eating protein interferes with its absorption, as does eating on a full stomach those foods that take long to digest. F 54 4 years
4/24/2006
 4  Parkinsons None noted. F 66 4 years
4/17/2006
 5  Parkinson's None cause I started very slowly with much less than prescribed to allow my system to get used to it. Very good / very bad. Classical situation where a drug seems to address exactly what is going wrong in the Parkinsonian's brain and that is the diminishing capacity to make our own levodopa (which is what sinemet is). Levodopa in a healthy person is made in our bodies from basic nutrients. Levodopa, in turn, is converted to Dopamine, which in balance with two other neurotransmitters, acethylcholine and GABA, provide for smooth and controlled movement. Throwing ready-made levodopa into our bodies causes a well known pharmacological effect called F 48 7 years
6/10/2005
 5  restless leg syndrome possibly night sweats, they started about the time I started the medication. The sweats could be from thyroid. Before I started taking Sinemet, I could not sleep for all the jerking motions of my legs. That problem doesn't exist with the medication. I take one every night 30 minutes before going to bed. F 47 7 years
4/30/2005
 5  Young Onset Parkinson's Occasional dyskenesia if I dont dose correctly, ON/OFF periods Saved my life! I medically retired at 33 from the Air Force. SINEMET is the medicine that helped, all the agonists had extreme side effects. SINEMET has allowed me to go back to work as an IT specialist. M 38 5 years
1/11/2005
 2  Parkinson's Extreme on off dyskinesia, dystonia, Cognitive problems of all kinds. Cramps, joint pain, muscle and soft tissue damage from dyskinesia. If someone had only told me that I would be totally overdosed and become addicted to this drug! What I thought was Parkinsons's disease is nothing more than the ravages of sinemet addiction. How do I decrease dosage and get back to normal Parkinson's disease and symptoms? M 55 5 years
12/25/2004
 3  Parkinson's Helps with freezing, limited side effects F 70 12 months
12/7/2004

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