SINEMET Reviews (LEVODOPA; CARBIDOPA)Average Rating: 2.5 (87 Ratings)Filter ResultsCompare SINEMET with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SINEMET: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SINEMET | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Osteoperosis | My father has been taking Sinemet for 5 years. He has experienced dreadful hallucinations, paranoia and psychosis. Shocking visions of ugly monsters and people trying to murder him and his loved ones. If he had alcohol at his disposal he would have become an alcoholic too, there we're signs of additiction type of behaviours. | My father began taking this drug at the age of 80 and we believe he was overmedicated by the nursing home he was living in. This high dose has now caused terrible mental problems for my father that he would have been better off without it and at least sane. | M | 86 | 5 years 250mg 4X day | 5/21/2011 | 4 | Sinemet | weight gain, sleeping problems | Works well for me so far. I also take Mirapex so don't know if Sinemet is helping or not, but with the minimal side effects, I will continue taking it. | M | 59 | 6 months 25/100 mg. 3X day | 2/19/2011 | 1 | help with dystonia of left foot | Tingling in my head and irratic heartbeat. | It makes me feel like I'm going to have a seizure and or heart attack. | F | 23 | 2 days 10mg 1X day | 10/18/2010 | 1 | parkinsons | hallucinations...confusion..joint pain.. upset tummy..depression moody sickness insomina nightmares | my dads been taking these meds for 3 yrs and has ended up in a terrible state constant hallucinations..sickness somnia depression his had to stop driving and hasnt been out of the house for a year... also i find theres not much help out there within the nhs for people with parkinsins his had parkinsons sine he was 53 12 yrs now its a horrible diesease that slowly takes the person u onced knew and loved x | M | 65 | 3 years 3X day | 8/4/2010 | 3 | Parkinson | Pins and needles in my feet making it hard for me to walk. Feeling sick. Sleepless nights. | I think that Sinemet should be taken off the market.It is clear that it is making people more ill than better. My brother took sinemet unfortunately he passed a away in February age 46 he been taking Sinemet for 10 years he always said that they were making him feel a lot worst,but he would not stop taking them because the doctor told him to take them,and my brother always said that the doctor knows whats best.He sufferd. | F | 47 | 2 years 62.5 3X day | 5/18/2010 | 1 | Parkinson's disease | Hallucinations, bad dreams, nausea, pain and itching in limbs. | These are side effects described by my mother. She was diagnosed with PD just a few years before her death. She said it stopped her tremors for a while, but shortly this effect waned and the side effects remained. She wanted off almost at once, but took them for some time because of the doctor's persuasion. | F | 76 | 6 months | 12/25/2009 | 3 | Depression/Anxiety/OCD | a weird burny feeling in my chest, worsening of OCD symptoms, a little bit more anxiety than before, | i take half of a yellow 100/25 pill ........overall, this medicine can help a little bit or a lot with the depression, but it makes anxiety and OCD worse, obviously. if u have no other options this can help with depression, but u should take it with an MAO-B inhibitor (such as selegiline or rasagiline) to prevent possible neurotoxic damage caused by the dopamine matabolism in the brain. | M | 18 | 2 days | 10/6/2009 | 1 | My Dad had Parkinsons. | Please see my orriginal note on 8/6/2008. I have included my email address. Dad became very delusional and we were afraid to keep him at home. He rarely slept and was combative all the time. He had me take him to the hospital so they could terminate his life. | Dad would rip out his IV's at the hospital. We couldn't keep him at home like this, so Mom and I decided to take him off the Sinemet. He was acting so paranoid and aggressive he would have to be locked up. We refused to do that. Dad became much happier and like his old self when he went off the Sinemet. We were able to keep him home until he died on Feb 1st of this year. This drug works great at first, then seems to build up and turn on the patient. In my opinion, it should be taken off the market. Find something else! I am putting my Dad's gender and age down. Take care! ALso...the neurologists were useless. They are bored with Parkinsons patients and keep pushing the Sinemet. It's up to you to find what works. | M | 81 | 1 years | 9/23/2009 | 3 | I have MSA with Parkinsons symptoms | Hallucinations and after 10 years my front teeth are cracking. | Sinemet helped with movement. I take 1/2 a pill twice a day. | M | 73 | 10 years | 9/7/2009 | 2 | parkinson | headache | M | 66 | | 8/6/2009 | 1 | PARKINSONS to help tremor | restless leg syndrome, insomnia, increased tremors | Initially I had a tremor. Prescribed sinumet and took for one month. I started having rls and insomnia after three weeks on med. Even after doctor weaning me off Sinumet side effects continued. Searched blogs and tried several ideas from them which included increasing protein in diet and avoiding citrus. In my case this worked and the side effects disappeared. | F | 83 | 1 months | 6/12/2009 | 4 | Parkinson's | Initial nausea, burning and bad taste in mouth, and some trouble sleeping. | HANG IN THERE if you can. Sinemet did improve my PD symptoms but it did take about six long weeks to get passed the nausea and some of the other side effects...I had to give it (Sinemet) a chance and just put up with the bothersome side effects for a while. I did find that taking the pills with a full glass of warm water and not taking them on an empty stomach did help. Sugar-free hard candy also helped with the bad taste in my mouth. Currently, I am in the process of adjusting the dose and adding an agonist (Requip) at bed time to find the right combination and dosages to best address my symptoms. Summarily, response to this medication appears to be variable just like the symptoms of PD. | M | 62 | 5 months | 4/6/2009 | 2 | symptoms after Keppra increase | muscle weakness in both arms and legs within 36 hours; inability to stand or walk without two large people helping to lift him up, in doctor's office, fatigue--whereas prior to drug he could walk slowly to bathrooom with a walker just fine. (In short, same results as when he tried this same drug in 2005) | It concerns me that the neurologists keep pushing Parkinsons meds like this one and Mirapex on my dad. An 84-year old man with a prior cerebral hemorrhage from a vehicle accident, who's on increased Keppra dosage needed to avoid new seizure problems, plus BP meds, cholestrol drugs, Terazosin, Plavix, Zoloft and others, who also has neuropathy, severe sleep apnea and no CPAP yet (getting retested) could have increased slowness, problems walking and falls for a number of reasons. I am guessing that treatment via Parkinsons meds for symptoms of slowness and falls is likely a standard AMA protocol once someone is in their 80's, even if other causes are a possibility, especially since Parkinsons diagnosis is limited to observing visual symptoms. Therefore neurologists are afraid not to prescribe Parkinsons meds? A respected Chicago hospital had already declared my dad does not have Parkinsons disease; only features of Parkinsons (shuffling, etc.), yet once we come back home, that's all we get from the local neuros. All I can say is beware: consider looking at other causes of the symptoms AND getting other opinions before using this drug--every article I have seen written by patients/families on the internet seem to contain a number of horror stories about this drug. I'm adding ours. Our loved ones deserve better. (Time length taking Sinemet in 2009: 2 days. In 2005: about a month) | M | 84 | | 3/27/2009 | 2 | PD | My mother took her first pill this morning and then I discovered this website and after reading several posts, I'm not sure if I should proceed with Sinemet. Please feel free to contact me with suggestions or recommendations. | My mother has what I would describe as "light" tremors in her hands which is a problem when she's eating. She also has problems walking sometimes. What's most important to us is that she has good quality of life. The comments about not sleeping, nightmares, nausia, etc. from taking this medication concerns me. | F | 75 | 1 days | 3/19/2009 | 4 | Restless leg syndrome | I would take one pill 3o minutes before bedtime and sleep for a good four or five hours. Then I could not get back to sleep. Now I seem to have restless legs during the day instead of just at night and on airplane trips. I like the medication for what it does for me at night but can't help but wonder if I am addicted to it inorder to get to sleep - and wonder why my legs are so antsy during the day - off and on. | F | 56 | 40 days | 11/7/2008 | 1 | Parkinsons | My brother has been taking this medicine and we have had so many problems with him, he is now in fact on remand for a crime we belive was caused by this drug, now he has spent time in a mental hospital he has been taken off this drug and is now his oldself again, This drug is awful and I would love to hear from anyone else that has experienced mental issues whilat taking, we need your help please. | PLEASE HELP | M | 55 | 4 days | 11/6/2008 | 1 | Parkinson's | My Husband has been taking Sinemet for about 7 yrs. Over the last year he has been having terrible confusion, insomnia and very bad dreams. We are now finding out the trouble is being caused by Sinemet. We went to a Parkinson's doctor and she told use she has heard the same comments from other patients. She said if it bothers you this much, just quit taking the medicine. So, as of today he will no longer take Sinemet. | M | 80 | | 10/3/2008 | 2 | undiagnosable progressive paralysis | upset stomach, vomiting after dosage, serious agitation, inability to listen, hear's a couple words of sentence, jumps to conclusion (sometimes very unrealistic), initial energy boost, drops a couple hrs later, frequent severe fatigue. | This chld doesn't have parkinson's, dosage times must be very carefully monitored, any deviation creates serious problems in physical and mental well being. a snack (not a meal) must be given 15-20 min after meds or vomiting will occur. Initially it did seem to help with fine motor control but I now believe the side effects are not worth it. She can't go out and play much when she gets sick 3 times a day. The agitation during the drop effects everyone in the home. She has always had trouble sleeping it is now much worse | F | 8 | 5 months | 8/25/2008 | 1 | Parkinsons | My Dad is taking Sinemet and it has been a nightmare. He is totally delusional now. He is extremely fatigued and sleeps quite a lot during the day. He is agitated and walks around at night. Normally Dad is respectful. Now he is mean and paranoid. I want him off this drug! Has anyone tried muscle relaxents instead of Sinement? Medical Marijuana? I want my Dad back! Dad is 80 and has been on Sinemet less that a year. | F | 50 | 1 years | 8/6/2008 | 3 | Parkinson's disease | Sleepiness, dyskinesia, mental slowness | For those recently diagnosed with PD: take advantage of all you can - you'll never feel better than you do now. I was diagnosed with PD in 2001. I've taken Sinemet for 7 years. After 6 years of relatively good control of my PD symptoms on Sinemet, I began to have dyskinesias or unintentional or dystonic movements and spasms. My co-workers thought I was drunk. But inside I was a mass of clenched muscles, especially in the jaw, neck, upper body. Sinemet kept me going rather smoothly for 6 years, but now I walk a tightrope between PD symptoms and side-effects. Sinemet also slows me down mentally, like I was drugged. (Laugh - I am!) These days I take a nap almost every day, out of necessity, in order to get through a work day, which for me is the evening shift. I'm a musician. | M | 55 | 7 years | 7/17/2008 |