EFUDEX Reviews

Average Rating: 3.4 (38 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 2  treat sun damaged skin Beyond the skin effects, I've felt agitated, irritable, exhausted, discouraged, anxious. There's gotta be a better way. going to ask the Dr. if the blue light or a laser would be as effective. The skin discomfort is no fun, but what it's doing to my whole body and emotionally makes me want to give up. F 64 20 days
1X D
 1  Cancerous and precancerous keratosi Horrible side effects. Pounding headache upon awakening. Burning eyes. Resorted to pain and sleeping pills to sleep. Lethargic. Sleeping. Depressed. Still waiting to feel better. I have done blue light tx. Much better. Wont do this again and wont know if it worked until next 6 month check up. F 71 3 weeks
2X D
 5  Actinic keratosis on face Tip: apply 2x daily on only each lesion for 5 days, then stop. Let AK heal for five days, which allows you to remove dead skin layers. Repeat this process at least six times, which is a month. Zero side effects. You can use Efudex on individual actinic keratosis lesions instead of your entire face, which is what I did. Worked amazing with no fatigue or chills. F 63 1 times
10 MG 1X O
 1  Leg press cancouruse treatment Burning like hell also travels to my arm back blisters Never ever will I use it. So upsetting F 7 days
25 mg 2X D
 5  Actinic keratotsis Not much up to now a lttle bit of redness and feel itchy but i now im only on day 4 they reckon round day 7 where the pain sets in F 57 4 days
2X D
 5  Skin cancer None and I'm taking aspirin 45mg per day M 59 4 weeks
5% 1X D
 4  Actinic keratosis and cancer (face) Aside from intended effects (redness, blistering, itching, burning), I experienced persistent insomnia and irritability beginning at around week 2 and lasting through entire treatment course. Brutal! Occasional headaches. No nausea. My dermatologist (a cancer specialist) was clear about treatment effects but did *not* mention side effects; I learned about them once they set in and I did basic online research. ADVICE: this is serious stuff. My course of treatment to date is 4 weeks of active use, then healing (estimated to be another 4 to 8 weeks). Know that before agreeing to this therapy, your life will be meaningfully impacted for up to 3 months, much of it in considerable discomfort. M 64 4 weeks
5 - FU 2X D
 4  Pre cancerous lesions on face Very tired. Nauseous and dizzy after applying which would wear off eventually by afternoon Total lack os sleep. Had to get sleeping pills from doctor. I could cope with the blistering and redness because I didnít have to apply to whole face. and at least you know itís working if it starts to get very red and raw. fatigue nausea and dizziness were horrid but the insomnia got me. F 60 30 days
5 1X D
 2  Sun damage to face, chest and back Was supposed to take for 14 days. I got the rash and blemishes as expected, mostly on face. On day 12 I was exhausted, shivering with headache. Next day I was freezing, nauseated with head and body aches. Called doctor who assured me it was not the cream but to stop using it. She also advised me to take a Covid -19 test. Did that yesterday. Woke up this morning felt fine then as About 1:00 pm got all the same symptoms as well as lost feeling in my right fingertips. Have not heard back from Covid test. Family upset as they must quarantine with me. F 57 13 days
2X O
 4  Actinic Keratoses Forehead Facial swelling - eyes almost closed up on day 27. Discomfort becoming pain from days 14-30. Skin felt like I was cracking concrete from day 14 onwards. Photophobia in couple of days after stopping treatment. Very unsightly (still so at day 30) Appears to have removed the AK's I was concerned about. M 59 25 days
5 2X D
 4  AKís on face Constant headache after two days of use and total lethargy and body pain. Worked well. Used on the forehead no problem but down side of nose became very scabby and sore weeping and crusty. Three weeks after treatment left with a red blotch down nose but hopefully this will fade. F 58 21 days
 4  pre cancerous skin leasions Fatigue, genrally unwell, face very irritated itchey painful and difficult to sleep-- very red and unsightly face-- added bonus when you work out your sweat burns as well -- 3 weeks to apply at least 3 more weeks to start to look normal and 8 weeks to get my running distance back Its pretty awful but you can get do it! I work in a hospital so i was lucky and surrounded by lots of supportive people but i did have to work the whole time. Aquafor did not work for me but "egyptian secret" did help- neutrogena gentle cleaning and natural baby lotion was also great for temporary relief-- i needed to wear makeup and later a hospital mask to cover when it got really bad-- 1 big hint-- you can wear lotion or make up and i waited 90-120 min to apply BUT wash your face first or you will get it in areas you dont want (i did full face but you dont want it in the corners of your mouth)-- there is also a green make up that Ulta sells for anti- red that i would highly recommend to help cover F 55 21 days
.5 2X D
 4  Sun spots on face My eyes were extremely gritty and stinging - had to stop using and eyes returned to normal Did not apply anywhere near eyes, but suspect it gets into the sinus system and somehow makes its way there, that's my theory. M 70 3 weeks
5mg 2X D
 5  Precancerous and cancer on face Extreme stomach pain, vomiting, diarrhea. Later mouth sores, ear pain. I never used Effudex for a whole area before...It did the job but still having side effects. F 73 3 weeks
 4  I spent my youth as a lifeguard. I was exhausted sleeping 15 hours a day. I felt very hazy as far as thinking. I applied to arms, legs, chest, neck. Perhaps too much at once. I believe it could have ended sooner had I applied 2x daily. Some spots remain, but took care of many. I don't think instructions for this drug are adequate. I feel like I lost 2 and 1/2 months of my life due to fatigue. Many spots are better from using it. Too many for removing by doctor. F 64 2 months
10 tubes
 3  Ak on arms. Just finished 7 days of morning and night applications. I canít believe the Fatigue!!!! Is this common? F 46 7 days
5 mg
 3  Basal Cell Carcinomas numbness, burning, skin is sensitive, achy body and tired, very red skin. I am just using this on my nose at the moment. I am on day 7 and my skin is red and oily. the reaction seems to have spread over my whole face because my whole face is red and inflamed. My nose feels numb and tight, maybe swollen. Almost on the verge of a bad headache. The exhaustion is what I don't like. and I really can't think it would be anything else but this cream. I am just tired! Will continue treatment until finished and I hope I don't have to do it again. F 38 14 days
5% 2X D
 1  Scalp skin cancer It was very painful and burnt my skin. I stopped using it about 3 weeks ago and it has left me with and unsightly rash on my forehead which won't clear. Much to harsh for normal skin. Very painful, made me very tired. Doesn't seem to have worked anyway. M 80 3 weeks
1X D
 3  Mild lesions It is a horribly painful and uncomfortable method of resurfacing the skin. Next time I'll just have it lasered. I've used Efudex before to remove minor skin lesions caused by too much sunlight exposure. It's like paint stripper, first it removes at least three layers of skin and the treated area goes bright red. I use cosmetic camouflage to hide it because it is so unsightly. The treatment is generally prescribed for 21-30 days, most people stop after 14 days because it is so painful. Fever blisters appear around the mouth the skin feels as though it's had class rubbed into it and for those sensitive to this stuff you will feel very ill indeed. I'm 17 days into treatment with another 4 days to go. I've reduced application to once per day because I feel so ill. With a compromised immune system I've developed a hacking cough, vomiting, temperature and I've been in bed for the last two days. I'll never use efudex again. Yes it works, but the pain is too great to justify the results. There must be a better way of removing AKs without going through such AGONY. F 66 21 days
20 MG 2X D
 4  BC and Keratisis sundamage Headaches ear ache on one side dull pain in ear tiredness sleepiness and skin feels burning as each day of treatment goes by This is third time I've used it but since I had a melanoma removed in 2007 I will continue to treat this way as to avoid any further melanomas appearing M 55 3 weeks

EFUDEX  (FLUOROURACIL):  This medication is used on the skin to treat pre-cancerous and cancerous skin growths. Fluorouracil belongs to a class of medications known as anti-metabolites. It works by blocking the growth of abnormal cells that cause the skin condition.   (Sources: U.S. Centers for Medicare Services, FDA)