EFUDEX Reviews (FLUOROURACIL)

Average Rating: 3.5 (45 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

EFUDEX  (FLUOROURACIL):  This medication is used on the skin to treat pre-cancerous and cancerous skin growths. Fluorouracil belongs to a class of medications known as anti-metabolites. It works by blocking the growth of abnormal cells that cause the skin condition.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR EFUDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Precancerous and cancer on face Extreme stomach pain, vomiting, diarrhea. Later mouth sores, ear pain. I never used Effudex for a whole area before...It did the job but still having side effects. F 73 3 weeks
30mg
8/18/2019
Email
 4  I spent my youth as a lifeguard. I was exhausted sleeping 15 hours a day. I felt very hazy as far as thinking. I applied to arms, legs, chest, neck. Perhaps too much at once. I believe it could have ended sooner had I applied 2x daily. Some spots remain, but took care of many. I don't think instructions for this drug are adequate. I feel like I lost 2 and 1/2 months of my life due to fatigue. Many spots are better from using it. Too many for removing by doctor. F 64 2 months
10 tubes
4/25/2019
 3  Ak on arms. Just finished 7 days of morning and night applications. I can’t believe the Fatigue!!!! Is this common? F 46 7 days
5 mg
1/1/2019
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 3  Basal Cell Carcinomas numbness, burning, skin is sensitive, achy body and tired, very red skin. I am just using this on my nose at the moment. I am on day 7 and my skin is red and oily. the reaction seems to have spread over my whole face because my whole face is red and inflamed. My nose feels numb and tight, maybe swollen. Almost on the verge of a bad headache. The exhaustion is what I don't like. and I really can't think it would be anything else but this cream. I am just tired! Will continue treatment until finished and I hope I don't have to do it again. F 38 14 days
5% 2X day
2/16/2018
 1  Scalp skin cancer It was very painful and burnt my skin. I stopped using it about 3 weeks ago and it has left me with and unsightly rash on my forehead which won't clear. Much to harsh for normal skin. Very painful, made me very tired. Doesn't seem to have worked anyway. M 80 3 weeks
1X day
6/16/2017
 3  Mild lesions It is a horribly painful and uncomfortable method of resurfacing the skin. Next time I'll just have it lasered. I've used Efudex before to remove minor skin lesions caused by too much sunlight exposure. It's like paint stripper, first it removes at least three layers of skin and the treated area goes bright red. I use cosmetic camouflage to hide it because it is so unsightly. The treatment is generally prescribed for 21-30 days, most people stop after 14 days because it is so painful. Fever blisters appear around the mouth the skin feels as though it's had class rubbed into it and for those sensitive to this stuff you will feel very ill indeed. I'm 17 days into treatment with another 4 days to go. I've reduced application to once per day because I feel so ill. With a compromised immune system I've developed a hacking cough, vomiting, temperature and I've been in bed for the last two days. I'll never use efudex again. Yes it works, but the pain is too great to justify the results. There must be a better way of removing AKs without going through such AGONY. F 66 21 days
20 MG 2X day
5/14/2017
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 4  BC and Keratisis sundamage Headaches ear ache on one side dull pain in ear tiredness sleepiness and skin feels burning as each day of treatment goes by This is third time I've used it but since I had a melanoma removed in 2007 I will continue to treat this way as to avoid any further melanomas appearing M 55 3 weeks
5mg
2/24/2017
 4  Arms top of hands and chest Itching irritated and have felt very tired. I'm only into week 2. It seems to be doing exactly what it is suppose to. F 53 3 weeks
2/15/2017
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 5  aK on arms back and face So tired 10 days into treatment Does anyone else feel tired after using it for a while? F 52 2 weeks
1/26/2017
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 5  Actinic Keratosis Itching, burning,bleeding at treatment area. Well worth the pain and effort. Will do it again when required. M 68 21 days
10 1X day
8/25/2016
 5  actinic keratosis Turned really red and scabbed up. Worked really well. Cleared up the 2 AK's on my temple. Just hope it stays that way. M 54 30 days
5% 1X day
9/10/2015
 4  Basal cell & actinic Keratosis Feel like I have a very bad sunburn. use it on arms before and did a great job. This time on forehead and scalp. Yes there is a burning sensation which is a well known side effect. But end of week 2 the skin under my eyes swelled up like huge blisters. It is hard to hide this. Doctor siad this is not uncommon and should disapear after I stop the treatment. I hope he is right. M 59 3 weeks
5mg 2X day
11/10/2014
 1  skin cancer Had basal cell carcinoma surgically removed from tragus (front of ear).left red,sore patch. All "nasties" removed. Advised to try Efudex. Have persevered for some time but to no avail. Consultant dermatologist says it is nothing to worry about but lying on that side is so uncomfortable. Efudex worked well on actinic keratosis on nose but no stinging, crusting or other reaction on tragus. Very puzzling. F 79 10 days
small
10/22/2014
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 1  skin cancer Had basal cell carcinoma surgically removed from tragus (front of ear).left red,sore patch. All "nasties" removed. Advised to try Efudex. Have persevered for some time but to no avail. Consultant dermatologist says it is nothing to worry about but lying on that side is so uncomfortable. Efudex worked well on actinic keratosis on nose but no stinging, crusting or other reaction on tragus. Very puzzling. F 79 10 days
small
10/22/2014
Email
 3  history of skin cancers on face At dermatologist recommendation used on entire forehead and each side of my face down to the level of my ears--all in one huge treatment. As others have said, my face was a horrible mess the entire time and very painful. I am age 86. It did what the dermatologist desired but 3 months later I am still experiencing nausea. Has anyone had a significant reaction what would indicate that efudes has a lasting effect on different parts of the body? M 86 28 days
5% 2X day
5/28/2013
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 1  actinic cheilosis I was to use this drug for 2-3 weeks for actinic cheilosis, precancerous sun damage to lips. After 4 days burning started and I stopped using the cream. Lips continued to deteriorate. On day 8 they were bleeding and burning horribly. On day 10 I went to the ER. Day 11, tiny improvement. I was to use Acetonide 0.025%, a steroid cream after the effudex treatment. But that cream also caused terrible pain and burning sensation. I look like a monster with burned, swollen lips. Only thing that helps is vaseline and soaking my lips in a bowl of warm water. Yikes. F 72 4 days
5% cream 2X day
11/11/2012
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 3  pre-cancer treatment Used it on my chest for 21 days and seems to have worked great but developed a rash on my back and stomach that persists after 4 months. Using it on my arms now and the rash is getting worse and spreading to my face. I hope it's a passing thing (doctors have said it's a typical drug rash and it'll go away) 4 months is a long time so I'm hoping they're right. I think if your sensitive, you can wind up with unpredictable side effects. It obviously enters the blood stream and can effect areas of the body that aren't targeted. Otherwise an effective treatment. M 60 21 days
5% cream 2X day
3/29/2011
 4  actinic keratosis Red skin, itching, scaling, not as bad as I had imagined. I am a month past ending treatment and still healing. I assume it worked. I used it on both arms. I was unclear about instructions of "light film" but apparently overused it because was soon running out and my dermatologist suggested decreasing to once daily. F 60 2 weeks
topical 2X day
2/14/2011
 1  For Bcc After 4 weeks many more lesions appeared on arms cleavage, breasts (started using on 4 lesions on rib cage). Stopped using efudex and many started to scab over. Once the scab fell off was bright red for 5 days then the erosion started and did not heal. Recommenced efudex use and now 4 months later the mess is unbelievable - large sores extreme pain. Doctor has told me to discontinue. Used on my face for 4 weeks and all healed very well. F 65 120 days
30mg 2X day
10/11/2010
Email
 5  Actinic keratosis First time use was about 25 years ago ago it was very effective at reducing frequency and amount of cryosurgies. The frequency of cryosurgies has started picking up again, so this is my second use. You can use it 2xday for 30 days and react pretty hard, or as little as 3xweek for 90 days for minimal burning. Its strong stuff and I can't imagine a woman using it "down there" like the lady rating this product a "1". But for face and arms, it was well worth the period of discomfort and unsightliness; enough so that I am doing it again. M 62 60 days
thin coat 1X day
4/26/2010

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