SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)Average Rating: 3.0 (158 Ratings)Filter ResultsCompare SAVELLA with similar:
Type: Rx Drug
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Results are sorted by length of time drug was taken longest to shortest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SAVELLA: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SAVELLA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | Fibromyalgia | I went off of Cymbalta and started Savella. This was in addition to Lyrica. Initially the Savella gave me more energy but it did not decrease my pain. I had to take more break thru meds. After 5 months, I weaned off of it and went back to Cymbalta and feel much better. | F | 50 | 182 days 50 mg 2X day | 8/31/2010 | 5 | Fibromyalgia | Initially, very nauseas and loss of appetite. As dosage increased, started at 12.5 mg and am now at 100 mg, so did the hot flashes, light headedness, dry mouth, and high blood pressure. | Even though the side effects continue, the freedom from pain, due to the fibromyalgia, has been worth it. I can now walk without a cane, and have no pain in my lower body. The one area that seems to be the stubborn one are my arms. I feel no relief in my arms, but the fact that I can walk without a cane, is a wonderful feeling. I have a lot more energy, and can even walk my dog, which I have not been able to do for years! | F | 54 | 60 days 50 mg 2X day | 9/19/2010 | 5 | Fibromyalgia, depression | None. | This has helped me TREMENDOUSLY with my fibromyalgia pain and depression. I haven't felt this good since before I had my two children. My doctor said this has been used for decades over in Europe for as a treatment for depression. Good luck! | F | 32 | 60 days | 6/15/2009 | 3 | body pain | Extreme sweating! Whole head would get wet and it would drip down my back. This stopped when I totally got off the Savella. | It did help with pain. | F | 58 | 60 days 50mg 2X day | 8/3/2010 | 2 | Fibromyalgia | Tremendous increase in arthritis pain--i.e., I had only manageable pain in my feet and it got to the point where I simply couldn't walk for exercise if I had done anything else that day. | Many other side effects that I am not so sure of--doc yesterday told me STOP TODAY. I have been diagnosed with fibro since 1988, am the anecdotal subject of a scholarly article. I urge anyone who's been recently diagnosed to start with generic gabapentin, which is a lot less expensive and a mainstay for me. | F | 53 | 60 days | 9/12/2009 | 1 | fibromylagia | Awful side effects. Hot flashes or Hot flushes and nausea-- | F | 57 | 60 days 25 to 100 1X day | 7/27/2010 | 2 | Fibromyalgia | Excessive sweating while feeling cold to touch. Heart racing and beating very strong. Blood pressure became dangerous also. Constipation and the feeling that bladder was leaking. | It took most of the muscle pain and nerve pain away and it was good to be able to get right up out of bed in the morning, but those side affects are worse than I have ever experienced with a drug. | F | 58 | 50 days 25 mg. 2X day | 9/9/2010 | 3 | Fibromyalgia | Hot flashes, sweating for no reason which caused a rash on my legs and arms, at times it feels like I've ingested poison. | I definately feel more energy and reduced pain. However the hot flashes and sweating became extreme after taking two 50mg doses a day. The rash is most likely from the sweating. The doctor cut my dose in half and its day 4 of the reduced dose. I feel terrible. The pain has increased everywhere in my body. I feel dizzy and I'm having nightmares. I rode out the side effects of the titration period and really thought this was a great medicine until now. Hopefully my body will adjust to the lower dose and I'll still be able to see some benefit since all of the other fibro drugs don't work for me. | F | 42 | 45 days | 10/21/2009 | 3 | Fibromyalgia | Nausea. Extreme heat flashes. | F | 55 | 45 days 25 mg at b 1X day | 8/16/2020 | 4 | Fibrromyalgia | High blood pressure developed after 14 days. | Other than HBP, this drug helped me more than anything I have ever taken. I feel like myself again. | F | 42 | 30 days | 6/9/2009 | 1 | Fibromyalgia - PAIN | My heart rate started going up. Then pressure in my chest and neck with palpitations. Also, it made me nauseous every time. This was on low dose and got worse as the dosage went up. Also sweating at night, mostly just before awakening. Light headed & out of breath at times. | First of all, I've had Fibromyalgia for 20 years. I'm in horrid pain. I also have Complex Regional Pain Syndrome from falling (Fibro imbalance) down the last stair and spraining my ankle badly, damaging the nerve. Then there's my Chronic Fatigue, Migraines, Cluster Headaches. They took Darvocet off the market. I used Gabapentin for my Fibro and it works pretty darned good and no side effect. But I get a lot of severe pain. I use Soma mostly for my muscle spasms. I try to keep my meds down to as low as I can tollerate without being too on edge of pain. I have gastritis so taking pills is no fun. Yes, I know how to take these pills properly. I went from getting obese from Fibro to now being skinny. I'm having difficulty keeping weight on at times. Like right now. I'm off the Savella because my heart pumping madly drove me nuts and felt awful not to mention light headedness and out of breath, as mentioned. Since it did nothing positive and did do somethings negative, I went off of it slowly. I can take none of the other pain medications out there and am really ticked off that I can not have my Darvocet. I am now on the Gerson Diet. It is extremely difficult. The positive thing here is, no Migraines and no Cluster headaches. Yea! God helps us all! | F | 55 | 30 days 1X day | 4/2/2011 | 2 | Depression | Initial startup was pretty hard. Lots of anxiety, muscle tension, etc. and at every dose increase. | Now I'm at 100mg. and for depression I would say it hasn't really done anything either way. I'm going to give it a full 5-6 weeks though and report back. | F | 47 | 24 days 50mg. 2X day | 11/21/2011 | 5 | FMS | HBP, disorganized thinking, irritation and impatience, high levels of joint an muscle pain with each dose increase for about 3 days | My husband and I are both on Savella for FMS. I tend to be depressed and anxious, he tends to be depressed and flat in affect. I started 2 weeks before him. I had high blood pressure, and the other side effects mentioned but stuck with my dose. He had high blood pressure and the same side effects; but he went back down to 12.5/day on his dose. He is coming off Cymbalta 10 mg qd. He ran out of Cymbalta and two days later started taking Savella at 12.5 qd. 5 days later he went to 25 qd. His blood pressure and heart rate increased. Instead of moving to twice a day dosing, after 2 days he opted to cut his dose to 12.5. His BP has remained high with the reduction. He is having a lot of memory issues and his pulse is 102 compared to a normal level of 68. I am on twice a day dosing at 12.5 per dose and am feeling much better. If I am late on my dose, I feel agitated and hyper, though.I put my gender down as male since I am mostly reporting on my husband. There are no male reports so I am hoping to see some soon or to see someone check in on their progress. The posts are mostly pretty old. | M | 60 | 21 days 12.5 2X day | 5/11/2010 | 1 | back pain, fatigue | excessive sweating, hot flashes, racing heart rate, extremely high blood pressure | still having back pain and fatigue | M | 41 | 21 days 25 2X day | 1/29/2011 | 1 | fibromyalgia | tachacardia severe, chronic diarrhea, . headache every day with flushing and hot flashes,breathlessness constantly during slightest exertion..scalp itching and loss and thining of hair by handfuls. | paired with brilinta (60 mg. twice a day) the breathlessness was unbearable..not worth the side effects for me...not one drug I have taken has helped with 30 years of fibromyalgia | F | 80 | 21 days 50 mg 2X day | 6/16/2021 | 3 | Major Depression | Nausea, Dizziness, Lightheaded, spaced out, increased anxiety and panic, blurred vision, mood swings, melancholia, high pulse rate, shortness of breath, Upper respiratory tract infection like symptoms, excessive sweating, hot flashes | Very shaky start up effects - anxiety and panic increased, felt an ominous fear all the time, mood swings and irritability, sometimes subtle euphoria and sometimes severe malaise and dysphoria. I think this drug is very dose dependent because of its very short half life of 8 hours. I felt disadvantaged because unlike other SNRIs like Effexor and Cymbalta there are almost very few patient ratings and information on use of Milnacipran in treatment of MDD. Side effects felt: Nausea esp first few days and when taken without food. Dizziness and lightheadedness, feeling drunk and spaced out. Blurred vision Hyper-emotionality mainly towards melancholia and sadness. Sleep - improved, but dreams are sometimes very lucid. Tachycardia - pulse upto 120 bpm, dyspnea Upper respiratory tract infection like symptoms - post nasal drip - sore throat, and nasty mucous - but without fever - which actually makes GPs treat it as allergy. Jittery, nervous and spaced out - especially in the evening when the effects kick in. This drug has apparently helped those who have failed ECT which should make it quite efficient, but I would suggest this to be definitely not the first line of treatment for MDD, and should perhaps be reserved for depression with anhedonia and apathy, not for melancholic depression. Probably its too early for me to have a definitive view. | M | 30 | 20 days 25mg 1X day | 6/3/2010 | 1 | Undiagnosed muscle pain | Constipation, Insomnia, Excessive Sweating | Ummm... This drug does NOTHING positive for me. No relief in pain. I was recentely told to down grade from 50mg 2x a day to 50mg once a day to see if that helps my symptoms. The constipation is better ( Thank goodness! )... But the insomnia is still there and as for the sweating, well, even my sweat sweats. I want off it but the doctor said to give it about 3 months.... And since I am desparate for relief, I am trying.... | F | 37 | 20 days 50mg 2X day | 8/8/2010 | 4 | Fibromyalgia | Much more energy, little bit of nausea at first, some sweating and heart palpitations | I am currently tapering off of Cymbalta. I am on 30 mg for the next 2 weeks and then I will be done. The Cymbalta worked great for pain reduction but caused more fatigue. I currently take Lyrica 75mg 3x per day in addition to the Savella. | F | 49 | 17 days 50 mg 2X day | 2/24/2010 | 1 | Fibromyalgia | drowsiness, severe hot flashes. I feel like I'm on fire inside. My muscles hurt so bad it wakes me up in the middle of the night. I can't get comfortable. Joint pain has worsened. Don't know if it's from the Savella. Just overal weak and tired all of the time. | F | 35 | 15 days 50 mg 2X day | 12/19/2010 | 4 | Fibromyalgia; nerve pain | Had tried Lyrical with unhappy results( constipation, head spinning, sudden hair loss, bloating). Rheumy suggested I try Savella. No constipation this time ( ialso had IBS which errs toward constripation)...in fact I think I am going more often. Sometimes I get a tingly feeling in scalp. Blood pressure only pre-hypertensive when I check it at work once a day. Get occassional lightning type headache...but also have that from nerve injury due to a fall I had 2 years ago. | I am not feeling as achy or least less aware that I am hurting all over particularly in my spine. I promised my rheumy I would try it for 5 or 6 weeks this time. So far...not too bad. | F | 57 | 14 days 50 mg 2X day | 12/11/2010 |