ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  stop smoking migraines, dizziness, paranoid, no sleep, no libido, agressive, listless, no emotion, zombie, shaking, cold sweats. Disorientataion, forgetfull This product should not be on the market. Zyban nearly ruined my life.It has taken me more than 2 weeks to recover from the side effects of zyban. I have had the most excrutiating migraines that have led to nausea and vomiting. I have experienced cold shivers and cold sweats to name a few of the symptoms I experienced. There were only two side effects listed that I did not experience. Do not take Zyban it will ruin your life or kill you(suicidal) M 33 2 weeks
150mg 2X day
10/9/2011
Email
 1  quit smoking redraised blotchy rash all over my body, wrist hand and finger swelling, trouble sleeping. i am really dissapointed cos it seems to work to stop you smoking but the side effects are very dangerous i have had this rash for about a week so far numerous visits to the doctor still no releif as yet people who are considering taking this medication should be well informed about it before taking it. F 33 14 days
1/24/2005
 1  to give up smoking i had every side affect listed i spent six days in hospital,and still having tests done.i had a bad rash all over and could not walk but had lots of side affects before this ie could not sleep bad dreams crying please do not take this drug it turns u into someone you dont want to be!!!!,my children tell me they want there old mum back.my doctor told me no side affects if i were told i would never had taken it.so please learn by someone elses mistakes. F 33 16 days
4/12/2008
 5  to quit smoking No side effects during the first week while taking 1 150 mg tablet a day, when dose increased to 2 x 150 mg tablets a day, I felt very spaced out (like I was on something), felt that I shouldn't drive and very happy. Week 3 onwards I haven't really noticed any side effects apart from if I take the second dose late in the evening (after 8pm) I have trouble sleeping. This medicine has worked well for me. I took 1 x 150 mg a day during the first week and stopped on day 7 when I increased dose to 2 x 150 mg a day. I can't say I lost the urge to smoke at all during the first week, but I didn't find it that difficult to stop on my quit day and I'm sure it was due to the zyban. Although I did suffer a few side effects during the second week I beleive it was worth it as it's really helped me giving up smoking. I read Allen Carr's easyway book too. I don't believe it's a miracle drug, there are still difficult times and willpower is required but it can certainly help some people. I have been taking the tablets for 5 weeks and plan to come off them in the next few weeks. F 32 5 weeks
7/15/2007
 5  Stop Smoking Dizzieness, headache, general feeling of crazieness I have been taking this for 6 days and have almost stopped smoking. The habit seems hardest to break and it feels weird not to smoke. I have been smoking since I was twelve and was up to two or more packs a day! People would laugh at me when I said I wanted to quit. This drug does make you feel crazy but hang in there it does get better and it works! F 32 6 days
9/28/2006
Email
 5  Stop Smoking Aggression and nightmares. Only took it for 4 weeks, got fed up with the side effects. It worked - I have now been smoke free for 7 months!!! Keep it up if you can. Now just have to work on the weight gain! F 32 4 weeks
3/9/2006
 5  Quit Smoking Irregular sleep patterns, weird dreams from day 5, more energy, slightly dizzy with headaches, rash on my hands day 6,mood swings and irretabill, not interested in sex - but go on for hours when intimate. Thankfull beond belief !!!! I found that even the worst outbreaks of anger and depression could easily be managed. M 32 2 months
10/29/2005
 4  Stopping smoking Ringing in the ears casusing partial deafness when there is background noise. Sleeping lighter than usual. Shaking hands. Unable to take deep breaths occasionally. This is my second time on Zyban and the side effects are the same as the first time. This tablet really works but you need a really strong mind and will to quit to get passed the initial side effects. I think you also need to realise that you are starving your body of nicotine which you are addicted to so not all sysptoms will be due to Zyban some will be withdrawals. If giving up smoking was easy people wouldn't need help to quit. I would recommend Zyban to anyone but warn them that they can make you feel ill but not for the whole course! Please don't let other peoples experiences put you off trying Zyban as everyone is different and lets face it stopping smoking is the best thing you can do for yourself. F 32 12 days
150 mg 2X day
9/2/2010
 4  To stop smoking I'm experiencing insomnia(sleep about 3/4hours a day), loss of appetite(need to loose weight so i think it's a good start), mild headaches, can't concentrate too long, skin sensitive I really want to stop smoking and rather go through a month of weirdness than be addicted to nicotine for a lifetime. Yes i saw some of the side effects being worse on others( friends went through this as well), but all of them pulled through. You can only pull through if you really want to stop smoking. I stopped smoking the 5th day of taking the drug. Btw did you know that if you take the drug as prescribed, that the effects won't be so hard? I made a mistake once by taking 2 tablets at the same time and was it hell that day!!!!! It does state 8hours between doses. This is my 3rd day of not smoking, had flu-like symtoms but I will pull through. Only another 2 weeks to get rid of this filthy habit!! F 32 30 days
2X day
8/10/2010
 3  To quit smoking In the beginning it made me UNBELIEVABLY aggressive, where I am usually a passive doormat. After that, nothing. No sleeplessness, nothing. I don't have any cravings for a cigarette, I have no desire, I am not stressed or irritable. Easiest thing I have ever done. I have regular spotting during cycles, and my skin broke out. F 32 40 days
3/9/2006
 3  To Stop Smoking Dreadful side effects. Started taking Zyban as directed, immediately quit smoking (Fantastic) But I have suffered very badly. I have had no more than two hrs sleep per night, tremors and pins and needles. Worse still I have had SEVERE thoughts of suicide and my partner has had to take time off work to watch me. I have felt as though I could quite calmly and methodically get in the car and drive at speed until I hit a brick wall. I have therefore stopped treatment before the tenth double up day, as there is no way on earth I could survive it. Be VERY careful if you have a history of depression, as I have and DO NOT buy this or any other mind altering medicine over the internet without Doctor's input. I would strongly advise against taking this drug if you live on your own. ZYban certainly quelled any interest I may have in smoking---Despite bad side effects I had absolutely no thoughts regarding cigarettes. It has kick started my quitting, but unfortunately It's effects are too severe for me to continue taking it. But, I will NOT be picking up the fags--and the rest is up to me:) F 32 7 days
3/3/2006
 3  quit smoking Insomnia. Irritability. Depression. Inability to talk with others. Feeling F 32 2 weeks
9/1/2004
 3  quit smoking Insomnia. Irritability. Depression. Inability to talk with others. Feeling F 32 2 weeks
9/1/2004
 3  give up smoking fuzzy head horrible taste in mouth only on day 5 not enjoying smoking anymore glad its helping tried patches gum and none done anygood F 32 5 days
4/10/2007
 3  depression In the very beginning, nausea-- intense brief waves of nausea. The nausea went away after the first few weeks. Overall side effects include mproved sleep, constipation, feeling a bit jittery, stressed, slight weight gain (few lbs). Since starting this drug I've also been experiencing a lot of yeast infections, which is NOT normal for me (approx. in 5 months). I tried several OTC treatments, pill from my physician but they keep coming back. I am wondering if it is related to the drug...but I haven't seen anything in the literature. I am planning to go off the drug to see if it helps. F 32 5 months
6/3/2008
 3  Depression No side effects at all Came to find out about Bupropion (Wellbutrin/zyban) myself while scrolling through the internet for an antidepressant that did not cause weight gain. I started on Sertraline in 2019 and it was fantastic, turned my life around within a week. Slowly increased the dose over 3 years until I was on 150mg, the low sex drive and weight gain of 18lbs was really getting me down. I asked the GP about bupropion he said it was only prescribed here in the UK off label but he was happy to let me give it a go. No side effects at all while coming off Sertraline and starting Zyban so much so I felt as though it was not working, 4 months in I am now taking 150mg twice a day, I still just do not feel like it is cutting the mustard, GP said I can increase to 3 times a day but I'm just not sure, I have lost no weight at all which was the main reason I started this pill, was hoping for a miracle I supposeā€¦ F 32 4 months
150mg 2X day
7/31/2022
 1  to stop smoking HORRIBLE! I only took it for 6 days and then threw the rotten tablets away! I experienced nausea, shaking, hot/cold, figity, vagueness, loss of appetite, and highly emotional (I have no idea how you can become depressed on an anti-depressant). I literally went nuts - strange phone calls to family and friends asking extremely weird things and no memory of it at all. I wish I could take this week back! I HATE it. I have never been so scared on a prescribed drug. The worst thing was that I could see myself going nuts and was powerless to do anything about it. F 32 6 days
6/24/2007
 1  stop smoking gran mal seizure My husband took this to stop smoking and one afternoon his eyes rolled up in his head, he screamed, grabbed his chest and fell out of his chair, kicking and smasming for four minutes. Now he's not allowed to drive, because it could happen again. Don't take this drug! It may ruin your life. Quit cold turkey, I did. M 32 6 days
8/5/2002
 1  No Smoking DO NOT TAKE THIS DRUG!! SPACED OUT MOST OF THE TIME, RASH ONE WEEK LATER, TO SCARED TO TALK TO PEOPLE AND IM A SALESMAN (13 YEARS) SHAKES. DO NOT TAKE THIS DRUG! M 32 9 days
150mg 2X day
7/16/2012
Email
 1  Quit Smoking While on the pill: Anxiety, depression, irritability, heat + light + noise sensitivity, weightlessness, you name it. Quit after 26 days and 3 years on: continous thoughts of hurting people, lack of social responsibility or desire to socialize, gas, bloating, liver problems, allergies, food sensitivities, weight fluctuation, extreme paranoia, hallucinations, you name it. 4 years after the "cure": things are getting better with the psychological side effects, still unable to trust anyone but at least no desire to hurt anyone or anything, the "tense, psychotic face and look" that this "cure" "covers" you with is now gone, digestive problems have worsen, uncontrolled flatulence i a major concern (no matter how funny it may sound), constipation, you name it. To conspiracy theorists Zyban's a governmental experiment of a mass-controlling solution. The way it's handed without explanation or warning makes you more suspectible to the reasons behind its' existence. It's a "mild antidepresant", but its side effects are way more dangerous than some of the most powerful ones. Why it's still on the market? Anyway, if you're +++ 100% to quit smoking, I can assure, you don't need this pill. Set aside 1hr for exercise and you'll be OK. 2nd, for those that lack strength to do it without help, unfortunately, if you are reading this, it is already too late to stop you from taking it and you will surely suffer for the next 5-10 years the consequences of your biggest mistake. For me, going through Zyban, was an eye-opening experiece that teached me not to trust any doctor 100%, but do my own research before taking any kind of pill or having any procedure done. I don't know which of the side effects experienced belong to Zyban or the nicotine &quo M 32 26 days
2/24/2007

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