ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  quit smoking Dry mouth, ants under my skin, insomnia I quit cold turkey back in 1998 for 2 years...and spent the next six months crying, anxious, paranoid and depressed. I would obsess over the simplest of matters and ended up getting so worked up a few times I ended up in hospital hooked up to an EKG. After 3 months I was suicidal, and decided that if I was not better by Christmas I would end it all...I had lost my mind but had no idea it was due to smoking cessation, as my father had given up a 40 year habit the year before without any outward signs of what I was going through. These symptoms are very real and very dangerous. We have been smoking for so long and become so dependant on it that I think no matter how you quit, some of us will experience such terrible withdrawals from the lack of whatever chemicals have been entering our body for so long (not just the nicotine) that the experience is almost unimaginable. My reasons for starting smoking again were stupid, and it was only when I tried stopping again with patches and the same withdrawals came back (albeit to a lesser degree) did I realise what I had suffered before was related to smoking withdrawal. With Zyban the psychological withdrawals were non existent and for this I am so grateful. This is my story and I just wanted to let everyone know some of us will suffer intensely when we first stop smoking no matter the method. Please listen to other advice posted here and ensure you tell your family and friends so they can keep an eye on you. Good luck to you all. F 40 28 days
150 1X day
6/18/2010
 1  Major Depression Shocking - extremely labile emotionally, paranoid, ended up suicidal My brief intro to this drug was a disaster. It's Australia's only way of getting "Wellbutrin" which is commonly used as an AD in the USA. It was hugely expensive as not covered by Govt for depression - and I lasted 5 days before realised I would not survive the experience. Jealous of those it works for, though, as there are no sexual side effects - in fact, improves things in that department. Would never touch again. F 50 5 days
150mg 1X day
6/9/2010
 1  quitting smoking ZYBAN SHOULD BE BANNED...I had the worst experience on this. Complete loss of appetite, confusion, anxiety (fear of going crazy), paranoid, slightly depressed and a feeling of being lost/spaced out. Couldnt sleep although i was very tired and couldnt keep still. Ohh yeah and dont forget the nightmares. I cant believe this shit is on the market. I've gladly taken up smoking again- because i'd rather smoke cigarettes then be stuck in a zyban phase. I realise some people dont really get the side effects, but i wouldnt take the chance, if you want to quit- go cold turkey. M 23 8 days
2X day
6/1/2010
 3  smoking cessation Do NOT drink alcohol when on Zyban! Unfortunately, I forgot and drank a double whisky. I spent a night in the ER, following the most unpleasant experience I've ever had. Extreme drunkenness, difficulty breathing, nausea etc. No other additional side effects noticed. Will continue with the course. M 44 6 days
150mg 1X day
5/29/2010
 1  Stop smoking Oh my, this was horrible, in fact I have 5 mins ago took out my nr 1 (golf) driver and smashed the remaining box with pills. Enough. The worst was the anxiety. I feel spaced out, so bad that driving becomes scary. Then there's the paranoia. I can barely type, and no, it is not a symptom of nicotine withdrawel, since I am actually smoking more now. Quitting with gum (as I have done in the past) is a walk in the park compared to this. Oh and forget about sleep, it's almost impossible, and when you do there's the most vivid dreams. Just pray they are good ones. All in all, I am not dissing Zyban, just for me it turned into a nightmare. It did, however, made cigarettes taste like crap and there was not that nicotine "hit" ie the first cigarette in the morning etc, hence is why I smoked more I guess. For some people it may be useful, but for me, this nightmare ends now. M 30 6 days
150 2X day
5/23/2010
Email
 3  Quit smoking Cant sleep, crying, mood swings, night terrors, Engery levels decrease. Although I can't sleep and cry over nothing I honestly think it's mind over matter I think zyban is great to quit as I haven't even quit yet I'm still in my first week although I have had bad side affects this drug dose work, the most intense side affect is my night terriors they feel so real and I tell u one thing they are horrible dreams were I wake up screaming I'm a happy strong person. If side affects get worse I might stop tAking them. As I said when I feel down I just remember that it the tablets n it's not who I am. Mind over matter F 22 6 days
2X day
5/22/2010
 3  Quitting smoking Ringing in ears, trying to take deep breath but failing to do so successfully, poor concentration, extreme out-of-it-state-of-being ie not there, detachment, can't handle rapid changing visual images, blurred vision, metallic taste in mouth, extremely tearful ie: would start crying out of the blue initiated by an odd passing thought, extreme feelings of hopelessness and despair, suicidal feelings..all in all the pills have made me turn into a person that is a shadow of what i was when I did still smoke. Zyban is worth it when desire to quit outweighs the side-effects, I just hope these will become less harsh as weeks pass by. Was fine during first week, desire to smoke became less up to a point during second week that cigarettes made me feel sick and nauseous. now it is the 3rd week and i have become indifferent to smoking it doesn't even feel like one is missing something. All in all, excellent way to be able to quit but a strong mind is key though to withstand the side-effects.Please mail me if you want to discuss further F 31 25 days
1X day
5/16/2010
Email
 1  To quit smoking Do not take this drug. I experience a change in personality, thankfully recognized by family members who recommended I stop taking the medication. I experienced clinical depression, which I believe was triggered by this medication for a period, immediately after taking this medication. It took 2 years to overcome the depression. If you want to quit smoking, make the decision, butt out and stick to your guns. Stay away from this "medication". Someone should seriously contact a lawyer about this stuff. F 28 10 days
30 mg 1X day
5/12/2010
 1  Yes I have taking Zyban for 2 days, and I stopped today. I dont feel ok at all, I have difficulties to write even now, I dont feel like i dont want to live and i will never be happy again, my eyes are blurred, i cannot concentrate, i cant bearly remember my conversations with people yesterday. i feel extrimely depressed. I DO NOT RECOMEND THIS DRUG TO ANYBODY. I WISH I READ ALL THE REWIEWS BEFORE I TOOK THEM. I LEARNED ONE THINK ALWAYS RESEARCH BEFORE TAKING ANY MEDICATION. I FEEL VERY VERY BAD,AND I HOPE TO GET BACK TO NORMAL SOON. feel free to email me. [email protected] Should be Banned forever! Its a very dangerous drug! F 26 2 days
10 mg 1X day
5/6/2010
Email
 1  to quit smoking PLEASE DO YOU HOMEWORK BEFORE TAKING THIS!!!!! DAY 2: DIDN'T FEEL LIKE SMOKING OR EATING - FEELING JITTERY A LITTLE ANXIOUS AND VERY SPACED OUT. DAY 3-9 COMPLETE LOSS OF APPETITE (COULDN'T FEEL HUNGER AT ALL) AND FEELING EXTREMELY FLAT, JITTERY AND ANXIOUS AND VERY DOWN. DAY 10: TASTED AN INKY TASTE IN MY MOUTH (VERY WEIRD AND SCARY) COULD NOT SLEEP AT ALL DAY 11: COULD NOT SLEEP AT ALL - AND MY THOUGHTS WERE JUST RACING ALL NIGHT - SO ODD. DAY 12: COULD NOT SLEEP ALL NIGHT LONG AND FELT VERY SCARED AT NIGHT. THIS IS DAY 13. IT IS 1:30 IN THE MORNING. I HAVE BEEN WATCHING MOVIES ALL NIGHT AND NOT EVEN A GLASS OF WINE CAN MAKE ME FEEL SLEEPY. I'M SO SCARED THAT THIS WILL CAUSE LONG TERM EFFECTS. THIS IS SUCH A WEIRD AND COMPLEX DRUG I WISH MY DOCTOR AND PHARMACIST WARNED ME OF THESE HORRIFIC SIDE EFFECTS. THERE IS NO WAY I WILL PUT ANOTHER ONE OF THOSE PILLS IN MY MOUTH. AND EVEN ONCE I ASKED MY DOCTOR IF THIS COULD CAUSE ANY LONG TERM HARM AND SHE SAID 'NO' I HAVE SINCE READ THAT PEOPLE HAVE HAD MAJOR LONG TERM EFFECTS. PLEASE DO YOU HOMEWORK BEFORE TAKING THIS!!!!! F 27 13 days
150 2X day
4/30/2010
 1  Stop smoking Doctor prescribed to help me stop smoking. Bt 3rd day was climbing the walls, unable to sleep, docotor gave me sleeping pills and increased zyban dose. That night my husband checked me into hotel as i was scaring our children. Next day I drove to a field and calmly put hose pipe from exhaust into car. A farmer saw me and i drove away. Went home to find rope to hang myself. My husband called ambulance and I was admitted to psychiatric ward. I have four children whom I love dearly and Before I took Zyban never had suicidal thoughts, or depression,panic, aggressiveness insomnia etc. Who would unless depressed which I wasn't? I took Zyban 7 years ago and from time to time I google the name and see the next lot of unsuspecting people the pharmacy company selfishly and knowingly make money from their misery, health and their family. A recent research study listed a well known and trusted journal examined in a randomised control study the effect of zyban on suicide and psychological impac Don't risk it at your peril! F 42 5 days
75mg 2X day
4/25/2010
Email
 5  smoking cessation For the first 7 days, I felt "wired" and shaky. My speech was disconnected at times. Then on the 8th day, I started the crying. Crying for absolutely no reason! Yesterday on the 10the day, I realized during the uncontrollable crying that I was feeling very depressed. Since I am normally bubbly and perky, this was alarming. Today, I am decreasing my dosage to 1 pill a day. After one week at this dosage, I will discontinue the medicine. For its intended use- in my case- smoking cessation, it worked great!! I have absolutely no cravings for cigarettes. Unfortunately, the side effects are too alarming for me. For anyone considering or already taking this medication, I urge you to have your physician monitor your progress and side effects. Additionally, do not stop this medicine abruptly. Consult your physician and decrease your dosage. Thank you to everyone for posting your experiences- it is nice to know that I am not going crazy- at least not by myself :) F 42 11 days
150 mg 2X day
4/14/2010
Email
 1  for smoking cessation As mentioned by the others here: paranoia, anxiety, sleeping little and waking up at 5:00 AM, depression, "feeling like a caged wolf" as another person here put it, seriously impulsive acts, mania, feeling like I was talking too fast, feeling like I could literally jump out of my own skin, inability to think linearly or function at work, I could go on and on. DO NOT TAKE THIS MEDICINE. I have taken a number of anti-depressants in my life and have never had side effects like this. This stuff is dangerous to your mental health. Please don't take it. Just quit cold turkey. The nicotine withdrawal alone will teach you the lesson you need to learn: that smoking has control over your life. Don't let Zyban control your life as well!!!! F 33 10 days
150 mg 1X day
4/5/2010
 4  Smoking cessation Depression, inability to concentrate, confusion, loss of all motivation, no desire to sleep with my fat wife but constant nagging lust for actually attractive women It works. I've taken zyban to quit smoking twice; once several years ago and again just lately. The first time I took the drug, it did work. I quit smoking. I also quit my job and left my wife-to-be to crash across the country. After coming back to and marrying this angry woman, I was cigarette free for a good while. Until we divorced and I started smoking again. So I tried all kind of things to quit smoking again over the last few years, and am finally resorting back to zyban. Again, it works. But I'm getting the same side effects as the first time. I'm starting to suspect zyban works by removing you of all of your motivation; right up to the point where you're not motivated enough to reach for another cigarette, let alone go to work or keep your fat second wife happy. She's on the way out. M 28 8 weeks
2 pills 2X day
3/15/2010
 5  To stop smoking First day, horrible taste my month, 2nd day, mildly happy all day, 3rd day - present, mildly nauseous at times & decreased appetite, which is not such a bad thing. Nothing major, which by the sound of this site, is quite lucky. I set my quit day at day 11, and up to then didn't smoke any less. Thought this stuff wasn't working, but was committed to the quit date... Quit day, got up and thought, Oh well, I'm a non-smoker now. So instead of having a coffee and a ciggie, I had a coffee and breakfast, not quite the same. The urge to have a smoke was there, but there was no craving for it. I found that reciting 101 reasons not to smoke in my head, stained fingers, heart disease, lung cancer, emphysema etc etc, helped in times when I would usually go for a smoke, like during commercial breaks at night. Anyway, it's now been 4 whole days and I can't believe that I've actually given up, no withdrawals... it was surprisingly easy! Almost too easy! I don't have any cravings and even thou its only been 4 days, I already know I won't go back to it, will take zyban for another week until I get used to not smoking... it's been awhile. F 30 14 days
150mg 2X day
3/11/2010
 4  Stop Smoking Paranoia, Bad mood swings, Violence, Dry mouth, Low moods, Empty feeling, Zyban is really great for giving up smoking. I have been trying hard to give up for over 2 years. I have been smoke free for 18 days and hardly want a fag. Although this is great, the side effects have been harsh. Ask my girlfriend, i grabbed her by the face during an argument. Something that i have never ever done before to anyone never mind a woman. This has shocked me deeply. The doctor informed me that this was due to mixing the drug with alcohol. NEVER DRINK ON ZYBAN-even a few. I would recommend Zyban for giving up smoking- but i think the mental side effects should be spelled out more clearly. M 31 25 days
150mg 2X day
3/9/2010
 2  quit smoking Swelling to face, hands. Pain in Hands and joints. Rash. Took Zyban for six weeks and it appeared to be working. Then my hands and face started to swell and by the time i visited the hosiptal i had breathing dificulties and i was in terrible pain all over my body, in particular my knee and elbow joints. Hospital told me Zyban is a very dangerous drug and would not recommend it to anyone and my doctor should not have prescribed yet when i spoke to my doctor before taking zyban he told me no reported side effects in Canberra and only one in New South Wales. I find that very hard to believe. M 30 6 weeks
21 1X day
2/16/2010
Email
 5  To stop smoking Insomnia, dry mouth, the occasional headache. This is a great product. I smoked for 19 years. I started taking Zyban and I stopped smoking on Day 8. I have not looked back and have no desire to smoke at all. The first few days were the toughest - all I thought about were cigarettes due to the habit I'd formed for 19 years. The occasional craving is there, but I remind myself that I'm no longer an addict and no longer need to smoke. They go away rather quickly. M 37 21 days
150mg 2X day
2/10/2010
 2  Smoking Cessation Dry mouth, forgetfulness, some shakiness in the first few days. Stopped smoking in the second week and did not have many cravings for tobacco at all. After I upped the dose to 2 pills started feeling really depressed, had days where I was crying uncontrollably, felt useless. Suicidal thoughts etc. Cried for days on end, which is something I never did before taking Zyban. My partner is taking it as well and she has some of the same symptoms, e.g. dry mouth, loss of sleep and appetite etc, but none of the physchological effects. I was about to make an appointment with my doctor regarding the depression when I found this site and realise now it is a common side effect. Have not smoked for 7 weeks so feel good about that, but this drug needs to be taken very seriously and I will be letting my doctor know the potential side effects. Have not felt this bad physchologically in my life. Would not recommend it to people unless they have tried everything else and they know the risks. Thought I was going mad. Hope to God this wears off quickly. F 47 46 days
1/27/2010
 5  stop smoking slight dry mouth - any other side effects were due to withdrawal from nicotine. Absolutely brilliant. It made my quit so much easier. Perhaps the bad experiences people describe are due to the fact that they are withdrawing from nicotine? Just a thought? I would definately say give it a go! F 50 14 days
1/25/2010

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