ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  to stop smoking From day 1 weird headaches, insomnia, constipation(extra fiber intake and lots of water is not helping much.Day 5- developed itching all over my body! My husband develepod the same effects plus stomach ache. He feels being drugged up. Cigarets do not taste the same any more- no more good feeling, Can't even smoke the whole cigaret unless I am really stressed out. M 48 6 days
7/6/2006
 3  Smoking cessation Urticaria, Pruritis, Flushing, Vasculitis Took zyban for 6 days (1+1+1+2+2+2) and discontinued on 7th. Had drug rash on 6th day itself but continued on 6th by taking 2 150mg. By 7th it was evident that I had a huge problem on my hand. Skin was itching all over and became red. Quit on 7th evening and has been off for 8 days now. Zyban helped with withdrawal for about 4-5 days after I quit zyban & nicotine. It definetely works by keeping the dopamine from being taken up. However, my immune system which is extremely tolerant to pill popping was not so kind with zyban. It brought out the big guns and started shooting up my body. Had blood vessels shot (vasculitis) and was put on stiff dose of 50mg prednisone for 7 days. Keep in mind that prednisone is not to be taken lightly. This is another dangerous drug which not used well can hurt you in the long run. But thank god for Prednisone tablets and cortisone cream without which my life would have been hell on earth for a week. All in all I'll give thumbs up to zyban for working o M 31 6 days
7/4/2006
 1  To stop smoking Anxiety, manic episodes, depression, insomnia. The first 3 days on a single dose was fine. The problems started on the 5th day when I was taking 2 pills a day, the doctor said to go back to 1 a day which I did but things did not improve much. Its 2 weeks since I've been off it and although the side effects aren't as severe they are still there. God only knows if I will ever be normal again. If anyone knows what to do next if the symptoms persists pls let me know. BTW another doctor told me this is a dangerous drug. M 35 7 days
6/28/2006
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 5  To stop smoking Insomnia Why are you guys in the U.S being made to stay on the drug for so long they are just trying to make more money out of you..Here in the UK its free and you only have to take it for 6 weeks and then you come of it, i think it would course alot less side effects if you didnt stay on it for so long F 24 5 days
6/26/2006
 5  Stop smoking! Days 1-6: Nothing but After i started taking 2 a day i found it slightly hard to get to sleep and would wake up earlier than i wanted and therefore would feel tired everyday! I am day 14 now and am sleeping a lot better but still feel tired most days. I had two days well i had CRAZY anxiety and depression. It was right after i started taking 2 a day, but it passed and now am fine looking forward to finishing the course and being smoke free! You honestly don't like smoking for the time you smoke on Zyban. I was smoking for the sake of it but putting the smoke out half way through. Once you fully stop then of course you get slight cravings but nothing you can't handle very easily. I luckily had minor side effects so i think the drug is awesome. The only thing you can do is try it and if it works for ya think what a change in your life that is! Good luck! M 22 14 days
6/20/2006
 3  For the sake of my health & wallet Dry mouth is a biggie - and oddly the ability to concentrate more, i've always been the type to have a thousand things going on at once and never get anything done! In the last week i've finished 3 projects that have been in the works for months. Hmmm. The other odd thing is the cravings (i haven't hit my quit date yet) have become stronger! I've been smoking more! and my quit date is in 2 days! I hope this works! Optimistic M 25 7 days
6/19/2006
 5  Nicotine Addiction! From day 8 through to about day 12, I experienced some minor headaches and very fitful sleeping patterns. I was not able to sleep until after midnight and was waking every 2 hrs. However, this did subside when I started taking my second tablet at about 1:30pm instead of about 5:30pm. I have had some tremors from time to time and some joint soreness but all relatively minor. I think you still need to want to quit. The drug won't do it all for you. I designated a stop day (about day 9 I think) and stuck to it. By then cigs had started to taste reall bad and I was less inclined to smoke anyway as I wasn't enjoying them as much. I'm still feeling the cravings, but the Zyban is definetly helping reduce their intensity. The big test was last w/end. Out in a bar until very late and managed to make it through the night without smoking. But it still requires individual self control. It won't remove the cravings completley, and you have to commit to the program. Good luck! M 33 18 days
6/14/2006
 5  Quit Smoking Some mild ear ringing, difficulty getting to sleep, only lasted for first week or two. Have continued to have increased energy and overall happiness. I quit smoking 4 months ago without the use of Zyban. I started having a lot of the side effects and symptoms that are listed here by some. This includes extreme anxiety,depression, mood swings, crying, unhappiness etc. After 3 months I thought I was going crazy and decided to try the Zyban and I immediately started to feel better and my anxiety and depression has completely lifted. I think many that have quit smoking and started Zyban at the same time are confusing some of the possible symptoms of quitting smoking and in fact some might be worse without the Zyban. Just a thought. F 40 4 weeks
6/14/2006
 5  To quit smoking The side effects I experienced are... dry mouth, mild insomnia and decrease in libido.. I decided to try this medication because everytime I tried to quit I failed.. I've been smoking on and off for 20 years. In the last 5 years quite a lot. I didn't understand how this medication could all of a sudden make you not WANT to smoke. By the 3rd day I noticed all of a sudden I didn't get the hit from the nicotine.. The cigarette starting not giving me the satisfaction it use to.. But I continued to smoke, I started to think I wasn't going to get rid of the desire to smoke. I couldn't believe that on my 11th day of taking Zyban I woke up and knew I didn't WANT a cigarette !!!! I couldn't explain it , it still amazes me how one day in my head ... I WAS DONE!!! It didn't bother me to not smoke, I could be around people smoking and still didn't want one. I wasn't grumpy or irritable. I'm on my 14th day and have no desire to ever pick up a cigarette again. I'm completely amazed and couldn't be happier !!!! This possibly could save my life from getting lung cancer !! Good luck to a F 38 14 days
6/13/2006
 5  To quit Smoking The only side effect I experienced was sleeplessness but it only lasted a week. I was getting up so early that I decided to change my work hours to start earlier. Not only do I avoid now being stuck in traffic, which has cut a good 50 minutes of my commute time, but now I have time to go to the gym. So, between getting up early and working out I get so tired that on my second week I was sleeping like a baby. Besides for sleeplessness (which went away on week 2) I have not had any other side effects. I quit smoking completely 5 days ago. I still think about smoking about twice a day but the urge goes away quickly. M 46 17 days
5/31/2006
 1  to quit smoking usually rational but a week after taking zyban starting feeling depressed. By week two had a major panic attack and couldnt deal with problems that normally didnt affect me at all. Have never felt as bad as this in my life, lost control and ended up having to counteract the drugs by taking vallium! Still anxious but cant wait for it to pass. dont take this, it turns you into someone different F 37 14 days
5/25/2006
 5  Quit Smoking none for the first two weeks, then anxiety attacks started and mild depressive feelings every now and then. After three weeks i couldnt manage to sleep longer then 0500 every morning, that is in my case 4 to 5 hours. So, i am f***ing tired but cant sleep , slightly to moderately depressed and i have had some anxiety attacks. These side effects will probably stick with me as long as i take the drug. BUT: I quit smoking as easy as can be, even before the stopdate i had no use for smoking, the Zyban takes off the enjoyability that is in the cig normally. And because you dont get the little "kick" from the nicotine you actually start wondering what on earth you are doing with that cigarette anyway. So. i have been off cigs for 4 weeks now, 6 weeks of Zyban, and the side effects are quite annoying yet hardly a problem compared to my addiction :) Dr told me that the side effects will go away a week after quitting Zyban so i dont really care anymore about the side eff, it will pass and i will be off the smoking addiction forgood :) After smoking more then 2 packs a day for more then 25 years and 6 attempts to quit with or without help and never lasting longer then a day or even an hour or two I F 38 4 weeks
5/24/2006
Email
 5  quitting smoking See below the one with the toedith2000 mail adress is mine, all i want is to correct the "time taken" number because that is the amount of weeks i have been smokefree, the amount of weeks i have been taking the Zyban is 4 plus 2= six weeks F 38 6 weeks
5/24/2006
 5  
5/3/2006
 5  Stop the Cig Habit At first, a little dry mouth but nothing I couldn't handle. No extreme side effects at all (lucky me). The only other issue I've experienced is a lack of coordination/concentration. This is not good for a drummer. There is NO WAY I could have stopped smoking without Zyban (at least a pack a day for 22 years). Really helps minimize the cravings and provides a "no big deal" attitude towards quitting. I am a little concerned about coming off the drug. Will cravings come back when I quit? Don't want to be dependent on any medication. Drinking intensifies the urge to smoke so I suggest avoiding excessive drinking. I haven't had a smoke in exactly 30 days (but who's counting). F 36 44 days
4/26/2006
 1  Smoking cessation Mixed affective state - depressed and high at the same time. Experienced some paranoia, extreme anxiety, difficulty sleeping, increased ++ sex drive, increased spending and suicidal ideation. Did help me stop smoking despite the above effects. I've never been paranoid or high before so this was frightening. Unfortunately started smoking again after 4 months. This all occurred 2 years ago. I've tried multiple ways of smoking cessation since, but am now back to Zyban - this time I'll take 150mg once a day and avoid the higher dose as this was when I started to have the negative effects. M 34 28 days
4/21/2006
 5  quit smoking as soon as I started taking Zyban I had increased energy and felt better than I ever did. Day 3 of taking zyban couldn't even smoke a whole cigarette, was wondering why I was smoking in the first place. It was not enjoyable anymore. Have been taking 1 pill a day for 3 weeks. When I tried 2 pills a day a felt like I was stoned. Tingling in my mouth and throat. Dry mouth. Drinking lots of water which is very good for you and quit drinking pop at same time. I wish I would have discovered this drug a long time ago. It's great. Everyone who smokes should at least try this drug. Also have been seeing a counsellor to quit smoking. F 37 3 days
4/20/2006
 5  quit smoking My comments actually start below this one...I guess I rambled on too long and got cut off...here's the rest of it: I also experienced visual distortions including blurrines, and off and on depth perception issues. I also experienced some back muscle pain and dry mouth. Things are calming down now. The nausea, however was gone by day 4. I still feel all of the above but 80% less intense. Now I'm tackling the lack of concentration and focus (having a thought in my head, forgetting it 5 seconds later, and then taking a couple of minutes again to remember what it was.) I haven't really experienced the emotional side effects that some have. As for craving a cigarette, I still do, but I find that I don't enjoy them as much. Also, because of feeling so rotten from the side effects, I simply forget to smoke as often! F 34 7 days
4/19/2006
 5  quit smoking During the first 3 days, I began to feel a bit light-headed and nauseous. Between days 4-7 I experienced some strong side effects. I've read all of the comments and am envious of those who received the desired result without going through these symptoms. I didn't find this website until last night and I'm glad I did. I thought I was having some bizarre adverse side effects that were not normal and was getting quite alarmed....should I go to the ER...wait to go to the doctor... But now I find that I'm not alone in my misery. Between days 4-7, I felt high as a kite...but not in a good way. I'd lapse into moments of extreme dizziness and then go back to the baseline high. My ears have been ringing since day 3 and this hasn't subsided yet. My brain did actually feel like it was twisting and my eyeballs felt like they were going to be sucked into my skull! I had the shakes and my hands are still warm and palms are sweaty. I have maybe had 10 hours of discontented sleep in the past 7 days. I Because I feel like I've tried everything else, I'm going to stick with the Zyban for a bit longer. If it really doesn't seem to help, I'll stop taking it....But I hope it does...and soon because I really don't want to take this drug any longer than I have to. I'm also supplementing the zyban with 45 minute sessions once a week with a public health nurse. From reading the comments on this website, I'm sure that many who have read it are thinking, "How can you keep putting yourself through the nightmare of these horrid side effects?" In response, I hope that, by suffering through the temporary lesser evil, I'll be able to rid myself of this greater evil that has controlled my life for 20 years. F 34 7 days
4/19/2006
 4  Smoking cessation 1. Dry mouth, strange tastes. 2. Dizziness - feel like I've had 10 pints, room spinning. Feel high!!! 3. Insomnia - waking several times per night, unable to sleep, nightmares. 4. Can't sit still, unable to relax at all. 5. Feel restless all the time, almost like I have the need to do something, but don't know what. This one is really spooky! 6. NO concentration! - Have trouble focussing on anything for more than a few minutes before wanting to do something else. 7. Muscle problems in legs - some discomfort as you get after strenuous excercise and some weakness. Feels like I'm going to fall over. 8. Emotional roller coaster - up and down to the extreme for no reason! 9. Feel very alert and wide awake almost all the time, even at bedtime and during the night. 10. Can't stop eating - I'm hungry all the time, no matter how much I eat! 11. Shakes. 12. Hot sweats, hot flushes (but, that's probably just the menopause (I'm male)!) The side effects are absolutely awful (apart from being high!), but as the drug stops me smoking, so I'm willing to put up with it. M 37 14 days
4/18/2006

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