SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  psychosis (manic depression) morning hangover, akithisia, chewing-on-tin-foil feeling for early part of the day, concentration probs, sometimes an increase to my appetite, physical heaviness and drag F 40 18 months
350mg 1X day
1/13/2011
 3  Bipolar II , Depression Nasal congestion,blurry vision sometimes,slurred speach after taking dose. Stiff muscles. Anxious. Severe cravings for sweets. muscle spasms.zombie like. sucking of tongue....don't know why. Feels like I am zoned out, not myself in my body (K Hole) like taking Ketamine. What I have noticed with Seroquel, if you are tired, as in worked hard, it will knock you off your ass. You will pass out within 20min of taking your dose. My moodswings were stable in the beginning, then they started acting out, so I upped my dose to 50MG. Some days I feel great, other days it feels like I want to cry my eyes out. Extremely horny, but no intension of doing anything about it, except when I drink. I know you are not suppose to,but I can't help myself.Drinking worsens the side effect quite severe though. Lately I wake up at night in cold sweats.Angry all the time. Still have moodswings. difficult to function, concentration is retarded. No consideration for other whatsoever. Some days my feelings are extremely high, like I am a god, other days I feel like I am being dragged into hell. The moodswings can happen withing minutes of each other too. Going back to the Psych in 2 weeks with my fiance. Don't think this works for me, too shit scared to try Lithium. I still get depressed, especially when there is a big change in my life, eg. was on holiday, back at work I will act out again. I used to take whatever drug I could get, cocaine, CAT,X, GHB to get rid of these feelings. M 29 1 years
25MG 1X day
1/16/2011
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 1  Bipolar ii rapid cycling constant "drugged" feeling; pressurised headache; nasal congestion; mental dullness; blurred vision; vertigo; sweet cravings; dry mouth; muscle weakness; apathy. Out of all of the medications that I have been prescribed I can honestly say that no others have been quite so debilitating in their side effects. I'd even take the akathesia of typical antipsychotics over the sheer weight of sedation I have with Seroquel. I'm sure it works wonderfully for some people. Unfortunately for me I've had to put off returning to work because of it. M 29 10 weeks
300mg 1X day
1/17/2011
 1  insomnia Extreme unnatural rapidweight gain. Muscle tremors/twitches. Thirst. Itchiness. This medication has played havoc with my physical health. I regret taking every day. If I knew the serious side effects of weight gain and physical addiction I would never have taken it for insomnia. I do not think that doctors take the side effect of seroquel seriously enough. F 31 10 months
300 1X day
1/24/2011
 1   Dry eyes, memory loss (words mostly) short attention span, trouble falling asleep, wake continuously throughout the night. Strange thoughts Wake to eat compulsively (never did it before) My Doc gave me Seroquel in order to sleep. I used to sleep when my head hit the pillow started to take Seroquel and started to have a hard time falling asleep and staying asleep. Have to urinate frequently during night time also can eat lots at those strange times at night. I decided to taper off and see if things I am experiencing are related to this drug, my doctor recommends Melatonin so I have started using it as well. F 53 1 years
25 mg 1X day
1/25/2011
 1  insomnia Nothing. I'm now dying to withdrawal. Seroquel is garbage drug used to treat "mental health" problems. Constantly monitor your blood glucose and cortisol levels. Seroquel can elevate these (adrenergic blockade). YOU CAN DIE TO WITHDRAWAL! INFO: Do not just stop if. AFAIK You should withdraw to long-acting alpha1 blocker (alpha2?) and carefully monitor you blood glucose and cortisol levels as they can kill you (=> diabetes). YOU CANNOT SAFELY WITHDRAW FROM HIGH > 400MG/NIGHT DOSES (DOPAMINE BLOCKADE) DO NOT CHANGE DOSAGE WITHOUT HELP. YOU CAN DIE. GO TO EXPENSIVE AND REAL PRIVATE DRUG REHAB CLINIC (COSTS LOTS OF $$$) BUT THATS THE ONLY WAY I THINK. BE VERY CAREFUL THOUGHT BECAUSE "HELPFUL" DOCTORS CAN JUST KILL YOU. YOU NEED *REAL* PROFESSIONAL HELP. DO NOT USE SSRIs. M 30 3 years
400MG 1X day
1/30/2011
 1  bipolar disorder + extreme insomnia Complete psychological and physical deterioration: ataxia, tremors, seizures, depression + suicidal thoughts, severe memory loss, deficits in logical thinking, aphasia, myoclonus, and hallucinations after taking my dose if I did not fall asleep within a half hour.Due to my already terrible insomnia getting aggravated by other bipolar medications, my doctor "had no problems" with me taking as much as 1200 mgs of this medication nightly (he supplemented my maximum allowed pharmacy dosage with free samples), and made no indication to me that such a dose could be dangerous. . I cannot remember the length of time I was on Seroquel, but during this period I suffered immensely. I shook so terribly that I could not sign my name on receipts or eat with eating utensils, had such difficulty thinking that I failed out of school, and somewhere around the time I realized I was having total black out periods, I began falling a lot while walking, and was hospitalized for a week for suicidality. Despite the fact that I had begun to show severe neurological decline in the entrance physical (could not subtract 7 from 100 or stand on one leg w/o falling) and my overseeing hospital physician acknowledged that I was probably being overmedicated already, dosages of some of my other meds were increased and a new one was even added. Shortly after leaving said hospital, I was hospitalized for seizure activity. Here, it was noted in my chart (I don't remember anything other than getting to the hospital) that I completely lost the ability to speak and could only grunt for a period of time. After the seizures were under control, I then also had fits of myoclonic jerks and could barely speak. It took me almost a full year to taper off of this medication (while the others took only a few months at most) and regain control of my life. Although I was also on various other medications, this was the only one I took at a high dose. For three years I was prescribed more and more of these "relatively safe" drugs, and I was almost completely nonfunctional for two of th F 22
900-1200mg 1X day
1/30/2011
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 1  Anxiety Bad side effects M 60
200 1X day
1/30/2011
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Patient History
 5  Bipolar None Ive been taking it on and off but I like that it makes me high and sedated. F 18 4 years
400 1X day
2/13/2011
 1  depression Bad, likely permanent damage to abdomen/colon/digestion. Can no longer eat a large variety of foods. Weight loss, extremely low mood, suicidal ideation Began at 25mg as an addition to Cymbalta. No effect on mood; upped to 50mg. Great for mood, but immediate, severe bloating/hardening of abdomen esp ascending colon. Dropped to 25mg with immediate cessation of abdominal symptoms. A few weeks later, asked my doctor if I could return to 50mg, as I really appreciated the cognitive boost of 50mg. I knew the bloating would return but felt I might be able to control it perhaps by managing diet; otherwise go off the drug completely. Bloating came back immediately at 50mg, was unable to control it, so tapered down to 0mg as per doctor's instructions. However, this time the bloating, rock-hard feeling in my colon did not go away and has been with me for 8 months. Symptoms vary in severity depending on what I eat. There is huge swath of foods I can no longer consume. This, plus the shoulder-shrugging, "there's no one who will help you with this" has led to bad depression and serious consideration of comitting suicide. I will be seeing a gastroenterologist soon, but I'd essentially been ignored until I got very angry with my doctor. M 47
50mg 1X day
2/19/2011
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 1  Paranoid Schizophrenia Seroquel caused me acute psychosis, visions and voices. It caused what it was supposed to heal. Affected the dopamine-center so that it caused the effects of early tardive dyskinesia in an age of 24. Trouble urinating. Blunt/drugged down feeling through out the day. Not a recommended medicine. Stay away if you can. WARNING: Causes severe blunt/drugged down feeling, tardive dyskinesia and Parkinsonism. M 24 1 months
350 1X day
2/28/2011
 5  bi-polar, anxiety, depression Weight gain, higher sugar Been the best thing for me. Yes, I experienced weight gain, but I take into account that it's made my bi-polar managable, so willing to put up with the side effects. I sleep at night now, and my moods have stabalized. It was the best thing I could have done, it's working well for me. M 51 2 years
300 1X day
3/4/2011
 4  Bipolar, anxiety, BPD, ASPD cant not take it or ill not sleep but dosnt help a lot to sleep weight gain i want to stop but every time i try i cant sleep get agitated worked up agressive anxious i would like to get off seroquel im currently taking the XR 300mg morning and 900mg at night F 21 5 years
1200mg 2X day
3/13/2011
 1  Depression Seroquel caused severe restlessness to the point it felt like my skin was being torn off, emotional liability, unusual behavior, nightmares and horridly painful muscle spasms. I had to put rolled up wash clothes in my hands at night so my fingers wouldn't curl up into my palm.I jerked so badly I slept in an upright recliner. It make me so sedated I was unaware of what was happening. One night I ended up in the Emergency Room with Seroquel-induced Pancreatitis/Diabetes (this is a documented side effect). I spent 3 months in the hospital with a tube down my nose.A physician diagnosed me with the worse case of drug toxicity he'd ever seen so I went off the Seroquel. Make sure someone who really knows you can monitor your behavior when on Seroquel. A doctor who only prescribes this may NOT notice how it has caused you to became erratic (Iatrogenic Illness).Seroquel is a major anti-psychotic and very very powerful.Consider NOT taking this drug at all. M 52 2 years
300mg 1X day
3/18/2011
 3  Self-destructive behaviors/insomnia Depression improved dramatically over time, insomnia disappeared, no major side effects but now after so many years somewhat concerned about long term dangers of Seroquel 300mg/Effexor XR 150mg. I plan to taper meds as soon as I move out on my own. I know still living at home under the tremendous stress/anxiety I am under, it is not a good time yet to get off meds which help at the moment cope better with my living situation. My father/brother alcoholic and my my Depressed/Borderline Blind elderly mother who depends on me for everything. Whatever you decide please consult with your doctor first. God bless us all and free us once and for all from Mental Illness. Awi :) F 43 6 years
300mg 1X day
3/20/2011
 2  Schizophrenia Seroquel caused me to have a rapid heartbeat, uncontrollable shaking of the hands, memory and coordination problems, confusion and loss of awareness. I ended up in a Mental Hospital for two weeks because of this drug. I started on 600mg at night and then Psychiatrist increased to 800mg. I could not think clearly, it affected my memory, I experienced acute confusion which resulted in me not being aware of where I was. I felt like I had lost control of my mind, a truly frightening experience. It had no effect on the paranoid delusions I was suffering from, it made me suicidal and all these symptoms continued for weeks after stopping the drug. Eventually these horrible side effects subsided, and I am now stable on Zyprexa (Olanzapine). This drug may work for some people, but for me it was a living nightmare. M 28 14 days
800mg 1X day
3/21/2011
 3  Anxiety & Depression The worst thing is the tiredness. I was almost passing out the first few days. I also had dry mouth. I noticed that after a few weeks that my sexual libido went way up. It also makes sex more pleasurable for me. I also noticed that my food tastes better to me and my appetite is way up. That's not a good thing. M 39 20 days
50 2X day
3/22/2011
 3  Borderline Personality Disorder MAJOR WEIGHT GAIN. Heart palpitations, dry mouth, slurred speach, hang-over feeling, loss of memory and concentration, sedated, extreme hunger. This drug worked wonders for my mood swings and insomnia. However I gained 60 pounds in 1 year! After taking 100 mg/per day for a year and a half, I was forced to stop taking it because I gained way too much weight in such a short amount of time. Now, 2 years later, I was just diagnosed with diabetes. and the doc. said its becuase of the Seroquel. I have not been able to lose the weight with dieting and excersize. i am only 23 and am now stuck with a major self esteem issue because i look like a fat cow. seroquel was great for what i needed it for - but PLEASE stop taking it if youre on it (with the help of a doctor, of course!). ist not worth the long term effects of your health. If you have any questions feel free to email me: [email protected] (no spam please) -- Rachel F 23 1.5 years
100 mg 1X day
3/23/2011
 1  Insomnia Blurred vision Palpitations Could not swallow Loss of self-control – smoking; major eating Lethargy Apathy Memory loss Hair loss Fatigue Weight gain (not very much but bothered me lots) Dry mouth The WORST drug I have ever taken. Taken for sleep. Ended up taking 25 - 50 mg. nightly. Would knock me out BUT got palpitations, Would need crackers then sweets (for no reason) including chocolate (which I hate). (I would have eaten a cardboard box). Could not swallow (even fluids) Finally would go to sleep and wake up breathing chocolate. Last straw was I have 2 cats and chocolate is toxic to cats. I dropped some chocolate and normally would have searched the floor with a magnifying glass but on that night (4:00 AM) I did not care enough to look and just covered area with a sheet. (December 26, 2010) never took it again. Question: Although I was *only* on 25-50 mg. nightly, it had MAJOR effects. It has been 3 months! But 2 weeks ago, I developed severe bone / muscle / joint pain (hip, sacroiliac area) and ankle swelling to the point I cannot hardly walk or get to my doctor due to pain. Could this be a late withdrawel reaction? F 40 7 months
25 - 50 MG 1X AN
3/27/2011
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 2  OCD, panic disorder destroys sleep completely. digestion problems, gave me chronic abdominal pain on my right, which would get worse after food even with low amount of fat, destroys memory and impairs you cognitively. yes it took care of my ocd very well - instantly. i was on 25 mg-50 mg a day for about 3 months. then it started worsening ocd and panic attacks. i had to reduce my intake and took it as needed. it worked well. even severe ocd episodes were reduced immediately. but as soon as i started taking it regularly again, the adverse effects came back. after about 2 years of using it on and off (3-10 times a month) i developed an almost chronic abdominal pain on my right and jaundice. i went off it for about 6 months and it subsided. however, it destroyed my sleep. i had a very hard time falling asleep and i was waking up every 2 hours. it's next to impossible to get your sleep back after this medication, i tried very hard (excluded all caffeine, tried to maintain good sleep hygiene, etc) never actually got it back completely. even if you do start sleeping a bit better after being off seroquel for many months, taking one 25 mg pill will throw you back to square one. i think when you're on these medications you really should listen to your body more than to your doctor sometimes and you should never ignore pains. yes for some people the benefit outweighs the side effects. but in my case it was replacing one problem with a bunch of others. F 37 3 years
25-100 MG 1X day
3/31/2011

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