ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Bipolar II, Panic Disorder Weight Gain. 20 lbs in 8 weeks -- no doubt it would have reached 100+++ lbs if had continued. You eat because you have to eat (will power has nothing to do with it) plus your metabolism changes radically. This drug causes blind, crazy hunger -- mostly for sweets. As a result developed Metabolic Syndrome (Sugar levels increased and needed to take Metformin to control, which it didn't. The minor side effects: tired in am, constipation, RLS and a tad spacey/loopy when ever I got tired. The best drug (combined with Zoloft) for mood swings, stability, anxiety, depression, mania and general happiness that I've ever taken. I felt great on this drug, 100% normal. Unfortunately the side effects of weight gain and metabolic syndrome got out of hand and I had to stop. I feel like Algernon -- I've had a taste of what normal people feel like and now I have to go back into my illness. If you can take this drug without weight gain and metabolism issues you may have hit the jack pot. F 50 8 weeks
11/15/2007
 5  depression with psychotic features Weight gain and diabetes, pituitary adenoma This was a good medicine for me for 8 years but now my physical health is in jeopardy. F 50 1 years
45 mg
11/11/2015
 4  depression and anxiety After DECADES of dawn insomnia (waking up too early), this drug finally makes me sleep (even a bit too much). Vivid dreams, often disturbing. Weight gain about 25 lbs. (always hungry). This drug worked wonder on my crippling anxiety. I was unable to work for years due to anxiety. Zyprexa reduced it to a manageable level, and now I am working full-time after almost 5 years of not working. It's an amazing drug. I started at 5 mg. every night and now am down to 1.25 mg. The weight gain IS a problem, and I've lost my sex drive, but it's worth it just to not be so anxious all the time. F 50 6 months
5 mg 1X day
10/20/2011
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 3  acute psychotic episode weight gain (60 lbs) It helped a bit. But it seemed that time is what healed me more. I would still get random thoughts (voices)on this medicine. Risperdal worked better with less weight gain problem. However the risperdal causes sexual problems. Check out Phieffer's treatment of mental illness with vitamins and supplements (located in Naperville, IL area). Less stress too in your life will help if you can do that. M 50 5 years
11/17/2005
 3   weight gain It helped some. I gave the wrong spelling for Pfeiffer Treatment Center and it is located in Warrenville, IL now. They use nutrition to help treat mental illness (vitamins and supplements). I hope this helps someone. M 50 5 years
11/17/2005
 1  72 hours hold for suicide I took a total of 10 mg and now I feel more terrible in my whole life. I want to commit suicide more then ever now. My sleep pattern of off and I don't enjoy life at all. I want to die. M 50 2 days
5 mg 1X day
3/30/2010
 1  Major depression Tardive dyskinesia and dystonia, akathisia, worsening symptoms. This highly toxic drug should be banned! F 50 6 years
11/29/2019
 1  Bipolar disorder Type 2 diabetes; weight gain; swelling of legs, feet, hands; restless leg syndrome. I had blood work done just prior to beginning Zyprexa and at that time my triglycerides were slightly elevated, but my doctor didn't feel it would be problematic. Unfortunately, he was wrong -- within 3 weeks I was diagnosed with Type 2 diabetes. I will be going off both Zyprexa & Serequel as a result of this 'side effect'. I strongly urge anyone who may be at risk for heart disease or high blood sugars to seriously weigh the positives vs negatives of taking these drugs, as their side effects are deadly. F 50 21 days
2/16/2008
 1  insane doctor incontinent, made me feel crazy, I would moan on my bed for at least an hour after having this drug. It dried out the skin on my hands. I hope they take this dangerous drug off the market F 50 9 days
6/6/2007
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 1  husband has bi-polar type 2 Takes med at night. Sleeps all the time! Comes home from work and takes a 3 hour nap, gets up, showers, goes back to bed. Next day constantly sits down and falls asleep. Also very crabby the next day until afternoon. Luckily we are business owners and the business has not suffered from this. Leg twitches at night. No drive or creativity. No sexual drive. Used to exercise all the time, now never. Weight gain. Did I say crabby??? The medicine did bring my husband's feet "back to ground", but that gain is not worth all the problems. I am very thankful I found this site. I did a google on zyprexa side effects and found you all. Reading all your comments and side effects sure made a light go on. Read a portion to my husband during lunch today and he immediately called psych doctor to start weaning off of it. He already has very bad diagnosed hypoglycemia....we certainly don't need anything to mess with his blood sugar. Because of all these side effects, we put our business up for sale, which was a huge mistake. We had an agreement with a buyer within a week, along with 2 back up offers. We were priced too low, but my husband had no desire or drive to continue the business. We are selling just because of the lethargy. We have 25 employees and pains me to think of how this will affect them. I don't know that the new owner will treat them like family.... they are all family to us. Will the new owner provide medical, dental and vision insurance to them cost free? Probably not. New owner has absolutely no knowled 50 9 months
8/13/2007
 1  Bpd Dont take it .you will feel worse every day on it.,....pray to good.. F 50 19 days
5mg 1X AN
1/6/2023
 5  Generalized Anxiety Disorder The day after my first dosage I had this weird feeling in my head. It felt like my head was a balloon and someone was blowing it up. Weird. It only lasted a couple of days. I was having problems with constant worry about nothing as well as chronic insomnia. After taking 2.5 mg of Zyprexia for 3 nights, I felt normal again. I wasn't worrying and I could sleep. I couldn't believe I had such a wonderful response to such a small dosage. I hope it lasts! F 49 7 days
3/22/2009
 5  Mixed states re Bipolar Disorder some constipation, some bloating. Works wonders. The best of all the atypicals. I highly recommend it. Also great for sleep. F 49 2 months
6/29/2006
 4  insomnia, severe depression Reduction of gag reflex, sleep 8-10 hours per night, hungry all the time, lots of energy I've tried Zoloft, Serzone and Seroquel. I've been on 150mg of Effexor per day for 4 years. I've experienced severe depression and suicidal thoughts, especially during the winter months. I was hospitalized two years ago. I was on Abilify for a month after the hospitaization but it is too expensive. I've been on the Zyprexa for two weeks and I've been very energetic. I've socialized more in two weeks than I have in two years. Maybe it's a manic episode but I'm hoping it is a result of the Zyprexa. F 49 2 weeks
5 1X day
10/4/2010
 4  Bipolar 2 , P.T.S.D Slurring speech, tremors, weight game of 60 pounds, crave any sweets I can get ahold of, lack of consintration, no zest for life, suicide thoughts. F 49 2 years
8/17/2007
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 3  schizophrenia weight gain; always hungry; sedation; apathy Helped tremendously w/hallucinations, but made some of the negative symptoms worse -- no emotion, no creativity, flat affect. I have to take it -- nothing else works. But I try everything else that comes out hoping to switch to something that doesn't cause weight gain. F 49 7 years
9/20/2007
 3  bi-polar disorder Dry mouth, excessive hunger (good thing though, had lost over 30 pounds prior to being put on medication,) decreased fine motor coordination with tremors of hands. Unlike most people, does not cause any drowsiness at all. I continue to experience insomnia. Other antidepressants and most cold medications do the same for me though. I take it now in the a.m. F 49 2 weeks
11/10/2006
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 3  Bipolar II I feel like a zombie, my personality is dampened. The zyprexa causes me to sleep 16 hours a day. I used the sleep-inducing quality to withdraw from Klonopin, so that was successful but I can't wake up clearly until the late evening. I also take 300 mg. wellbutrin XL and 150 mg. effexor daily. It's disrupted my reading ability. I haven't experienced weight gain but I do feel hungry all the time. I often feel numb, like I'm two steps behind everyone else. If anyone can relate to these symptoms, I'd appreciate a response. I'd like to know if the zyprexa is causing me to think I have brain damage, or if it's something else. F 49 4 weeks
9/16/2006
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 2   diagnosed with schizoprenia after being knocked off my pushbike on noosa parade on 10th august 12.10 pm 1998.blood exuded from mainly left ear,eyes in serious state after confirming later on with ambulance staff,fractured skull left temporal.soon after had anxious moments for no emotional reasons.found out it was possibly side effects of morphine from paramedic with energex community rescue helicopter and later in hospital during my long 3 day stay[couldn't wait to get out].paranioa and distrust of people,lack of vitamins and minerals,soft tissue damage,spine and nerve damage,emotions of post traumatic stress because of what was happening afterwards. . .it goes on . what i needed and still need since the accident is time at a health farm for at least two weeks. i am currently and have since may 2006, been on resperdal. i find it satisfactory until i learn more. also because i have consumed alcohol for the last ten years and am the sucker on the end of the smoke, this is a pertinent F 49
11/1/2008
 2  Bipolar/GAD/PTSD Although this agent initially took me out of an acute psychotic episode the side effects have been pronounced. The worst side effects seemed to occur after I had been on 5 mg/day for several months. I gained 25kg in weight and my cholesterol went from normal to 8.4. (I have also been taking Remeron for depression and this may have also exacerbated my weight gain). After several more months on this combo, I have noted the following disturbing symptoms: intention tremor/apraxia with handwriting, vertical twitching of facial muscles (esp. cheeks), dyslexic typing on keyboard, inability to focus on task at hand, difficulty getting out of bed (want to sleep in), tiredness, feelings of despair. Currently on 2.5mg Zyprexa in morning and Remeron 15mg at night. Feel like a zombie in the morning and usually wake up feeling depressed that I have to get up and out of bed!! Continuing difficulty focusing on task at hand. M 49 8 months
7/15/2007

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