ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  bipolar 1 Weight gain Zyprexa is an amazing drug. After trying numerous other meds, zyprexa is the only one that has kept my depression and mania from returning. The only side effect has been weight gain, which bothered me at first but I am used to it now. Overall, I think it is a great medication. F 29 1 years
10 mg 1X day
11/9/2011
 5  depression and anxiety Serious weight gain, and not just because it made me hungrier, but because it messed with my metabolism (glucose levels). Most meds that make you gain weight do so because they just make you hungrier. Not so with Zyprexa, which can even cause Diabetes. Other side effects: sleepiness (but I wanted that), and anxiety when I missed a dose. I took 2.5 mg (5 when I was having situational problems). No sexual side effects. Oh, Zyprexa, How I love thee and also how I hate thee! I have treatment-resistent depression, with mild OCD and anxiety. I took Serzone 400mg and Wellbutrin XL 450 mg with no results, and my doctor decided to try Zyprexa to help "activate" the other drugs. It saved my life. I felt better within a week (after 6+ months of crippling depression), and it did not cause euphoria or significant cognitive changes. It just gave me a nice "buffer" between my anxiety/emotions and the outside world. This drug works for me. 2.5 was great, and I could take 5 when I had situational difficulties (short term) and I could tell the difference between the 2.5 and 5 in terms of my "overreaction" likeliness. I felt better than I have ever felt, it helped me sleep, and it did stabilize my mood. However, the weight gain was significant (20 pounds in a year or two), and the risk of Diabetes made me decide not to keep taking it as a long-term med. We will use it again s F 29 2.5 years
8/25/2006
 5  depression and anxiety same as below (I posted there, too, but it cut off my comments) We will use it again short-term if I ever have a major depressive episode again. It was a difficult decision to stop taking it, because it really did help me, but I am sticking to the atypical antidepressants, and Lamictal (to replce the Zyprexa) so long as I am doing okay...but I will not hesitate to go back to Zyprexa if I absolutely need to. I just wish the side effects weren't so awful. Weight gain is a big downer for me, because it makes me more depressed. F 29 2.5 years
8/25/2006
 5  Schizoaffective I haven't experienced many side effects. I must be one of the lucky ones who has not gained any weight-I am naturally thin. I don't feel tired but I do act slighty zombified for the first few hours after I take a dose. So I split the dose but take them both later in the day when I am home. Zyprexa has helped me much more than seroquel with voices and depression. Don't let others scare you. Try it for yourself. F 29 2 months
10mg. 2X day
8/15/2013
 5  Depression, Anorexia N,O.S. Anxiety Better Sleep, reduced intense fear and mood swings, better focus, cold sweats at night, increased fear in open spaces, everything was harder on my body that was semi-strenuous, heart palpitations that finally made me quit. I really need this drug to find a replacement to Remeron for reasons specified above and my medical history. None of my problems are intentional. I don't understand what has happened to me. What I can say is Zyprexa means the very best and the very worse to me- I"ve taken it briefly 3 times- and lasted a month max all 3 times. I by far love this drug the most, but after getting heart palpitations (was already having stomach distress after eating I noticed), I gave up out of fear. ONCE AGAIN MEDICAL INDUSTRY: Thanks for breaking my heart. But don't you know fellow patients: "We Never Try". To the medical industry: F YOU. -Andrea F 29
12/26/2005
 4  schizoaffective or bipolar disorder excessive sleeping; gained 30 pounds but then stabilized really does well at keeping unwanted and persistent thoughts out of my head; makes me more relaxed and content; moods/energy level are more stable now instead of always up and down M 29 5 years
4/18/2005
 4  bipolar mania/psychosis weight gain, drowsiness, craving sweets although this med makes me eat like a pig and knocks me out at 9pm regardless of when i take it, its the best antipsychotic to treat my manias and paranoia. i've tried other AP's like seroquel, geodon, and risperidal, and they didn't help much. i take 20mg zyprexa a day, have for almost 2 years. blood sugar and all other blood tests have always been normal F 29 2 years
12/1/2009
Email
 4  Schizoaffective I have gained a lot of weight.. 70 lbs in 1.5 years. I used to be really beautiful but now I am just huge. The medicine has done well at controlling my paranoia and thoughts. My thoughts are organized again and overall I feel pretty good. I just wish I didn't have to be so big. F 29 1.5 years
7/8/2008
 2  Bipolar/BPD Intestinal Upset, EXTREME fatigue during work. Hey, it wasn't LAMECTAL (sp?) with the awful slurred speech. Going to look into something else. F 29 5 days
5/27/2007
 2  Schizophrenia Tremendous weight gain, tiredness. Hope you have nothing better to do than sleep all the time, because zyprexa might make you feel pretty tired. I also gained 40 lbs in three months. F 29 1 years
8/13/2005
 2  Anorexia, PTSD, Depression Gained 50 pounds in less than 6 months. Even on 2.5. Was pregnant too, but still. No way did I eat enough to gain that amount of weight. But if it saved my baby it was worth it. Just bad situation all around with anorexia and pregnancy. I wish I was given all the info about it. Like extreme weight gain with small amounts of the drug. F 29 6 months
2.5 1X day
5/14/2011
 1  depression weight gain, constant hunger, felt tired and fell asleep at 7 PM, could not concentrate, lived like an animal - no thinking or mind I do not recommend to try this drug. I gained 40 kg and I felt like a robot. If you have ideal or lower weight you are more likely to gain more! This drug is pure shit and can cause diabetes!!! F 29 3 years
10 1X day
3/22/2010
 1  Psychosis weight gain, increased appetite, tiredness, lethargy, memory problems, loss of creativity, seizures M 29 14 days
20 mg 1X day
4/4/2012
 1  bipolar Sedation at first, loss of interest in pretty much everything, boredom, trouble making decisions Over the past few months I've noticed a severe decrease in things I used to enjoy, and this correlates exactly along the same timeline that I've been taking this med. It definately stabilizes my mood, but I find I'm sorta just "existing" and passing time, not interested in much of anything. Haven't been to the gym in weeks, whereas I used to go routinely. I've had days where all I did, all day, was just watch TV, when there was stuff that needed to be done....it was an ordeal just to get off the couch. My guitars are collecting dust, my apartment needs a good cleaning, yet all I want to do is crash on the couch and watch TV, even though it's hard to find pleasure out of that as well. I'm not myself at work, I'm less productive, less helpful, it's awful!!! If I were to graph my moods while I've been on this, it'd be a straight line in the negative. Same thing happened with Depakote ER, Trileptal, and Lithium. I'm beginning to think mood-stabilizers aren't for me. M 29 5 months
10 1X day
4/25/2012
 1  Schizophrenia Zyprexa (Generic: olanzapine) used by millions of Americans to Schizophrenia and bipolar disorder has been linked to linked to, high blood sugar and Diabetes, Hyperglycemia, Ketoacidosis, Pancreatitis, Neuroleptic Malignant Syndrome (NMS), Tardive Dyskinesia (TD), Diabetic Comas and death. M 29
6/30/2006
 1  Bipolar (psycho hyper mania) Needed to sleep at least 15 hours a day (made me late to work every day for about a year). Made foods taste unbelievably better-I could easily eat artificial junk food like Krispy Kreme doughnuts that actaully taste horrible (I'm not a big junk food eater I prefer natural foods). Gained 35lbs in 2 years (I'm pretty good looking around 185-190lbs compared to other guys so that was terrible). Twitches, muscle spasms, shaky hands--mine are usually very steady. Didn't care about anything at all. Lowered my IQ by at least 40%, but that was a plus because it made it easier to fit in with normal people. Basically I became a normal person: Fat, ugly, dumb, senseless and boring. This is good for people that are a danger to themselves or to society, but not for those that can function in everyday life. Being hungry all the time is a form a torture-especially when everything tastes so good and you just ate a huge meal that would make you throw up if you weren't taking this medication. M 29 2 years
10/9/2004
 1  schizophrenia type paranoid gained 30 lbs in 30 days, extremely bad tremors, dyskinesia I was taking this medication while living in an assisted living facility in Palatka, FL and the tremors were so bad that I was no longer able to feed myself or even get a cup of water to my face without getting completely soaked. I was taken to Shands Neurology and was told that if the tremors didn't subside after discontinuing the medications that it was possible that I had early onset parkinson's disease. To be fair I was later diagnosed with Essential Tremor Disorder, but never before or after this medication have my tremors been that severe. It was great for symptoms, but the side effects far outweighed the benefits of taking the medication. M 29 1 months
7/23/2007
Email
 1  bipolar This antipsychotic gave me DIABETES. WARNING: DO NOT TAKE THIS MEDICINE, ITS DANGEROUS. JUST READ ALL THE LAWSUITS TIED TO ZYPREXA. M 29 6 months
10/10/2009
 1  THC consumption difficult thinking to talk, drowsiness, always tired, bad bowel function, frecuent diahrrea, do not listen to anybody that tells you to take this poison even your doctor, the withdrawals from this drug are extreme. pls dont be a fool. M 29 4 years
5 mg 1X day
2/5/2020
 5  bipolar mania sedation, dry mouth This is awesome as a short-term drug for mania. It made me feel normal FAST. It is sedating, which I did not like since it really made me feel like I was dragging. It was hard to get out of bed in the morning. I definitely would not want to take it long-term because the sedation kind of sucked. But I'd rather feel tired and slow than feel manic and paranoid. For what it was prescribed for (to short-circuit a manic episode), it was amazing, so I am still giving it a 5 despite my mixed feelings about it. By the way, I did not gain any weight at all. I was taking 15mg. F 28 10 weeks
9/1/2007

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