ARIMIDEX Reviews (ANASTROZOLE)

Average Rating: 2.5 (1431 Ratings)

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 ANTINEOPLASTICS AROMATASE INHIBITORS

 Type: Rx Drug

  

ARIMIDEX  (ANASTROZOLE):  Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1995-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ARIMIDEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ARIMIDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Early stage breast cancer Very Severe, multiple, debilitating and long term ill effects not recognised by my medical team and still repeating after 9yrs Accumulating almost every side effect on the Patient Unformation Leaflet I was a person with no underlying health issues. Stopped Anastrozole after 2 yrs 2 months due to extra sensitivity to interchanges of generic brands of Anastrozle. Told by my Breast Care Nurse that I may never be the same again. Thought to be psychological. I addressed that much to the astonishment of my Consultant. It was not psychological. The interchange of generic brands of Anastrozole caused overdosing several days after new brand. Each change upped the intensity of ill effects and added further Ill effects due to the differences of the half life of the Active Ingredient. After stopping problems withdrew for the same period of time that I was on Anastrozole and some were worse creating more difficulties. To cut a long story short - the mix of Anaesthetic, Radiotherapy, Omeprazole for Hiatus Hernia together with Anastrozole at the start of my treatment has caused havoc to my nervous system, my muscles, connective tissue, skin rash, blisters and sores, bladder and bowel incontinence, falls, fractures, difficulty walking, unable to do my household duties, mouth peripheral neuropathy, tooth problems and now a suspicion of Glaucoma. I have also had surgery for a hip replacement and endometrial cancer. More Anaesthetic, more Radiation, more Morphine reviving the ill effects established by Anastrozole. Plus for several months - Ranitadine. No one tells us that Anastrozole is a cancer chemotherapy agent derived like all other cancer treatments from nerve gas, mustard gas produced for warfare during WW1. F 78 0 days
1mg
1/29/2021
 1  Breast cancer Bad upper pain and nausea also heat and feeling like pins and needles everywhere even in the face , stopped taking this drug about a month ago and have not been the same since , severe gastric pain and lost 13 lbs severe nausea and now tingling everywhere Also thought I was having a heart attack pain was severe after stopping this nasty drug F 58 10 months
10 1X day
4/12/2022
Email
 1  Breast cancer Insomnia, anxiety, depression, foggy brain, heart palpitations, crying. Anyone out there with heart palps? Had a complete evaluation and three tests all normal. Palps due to drug and lack of estrogen in body to regulate heart. F 76 3 years
1 mg
6/24/2020
Email
 1  HER2 positive breast cancer Scary cardiac side effects - heavy pressure in my chest, wheezing, heart racing and palpitations-the worst acid reflux I have ever had in my life - started with joint pain in the first month and turned into respiratory/cardiac/gastro side effects after it built up in my system NOTHING worked on the acid reflux. Eating bland diet gave me terrible acid reflux. Went to my PCP and she looked up the side effects of Arimidex and told me that 40% or women taking this drug have artery problems and gastro problems. She took me off it for a two week trial and I felt better in two days. I have not taken it for the past 6 weeks. I met with my oncologist and told her the horrific cardiac (and gastro) side effects I was experiencing- she said because my EKG was fine I was probably having a panic attack! Really. A panic attack for FIVE DAYS, all day long, where I felt like at any moment I was going to have a heart attack???? NOT a panic attack. A doctor's answer to anything they don't know - panic attacks. Wheezing, congestion, chest pressure and terrible gastro problems. She suggested Tamoxifen as a replacement for Arimidex and I refused. Gave me a prescription for Letrazole (which I have not taken yet) because being that it is a "sister" drug of Arimidex I assume it will have the exact same effect on me. The bottle comes with a very length report on the side effects it has given women and they are all bad. I get that HER2 positive breast cancer is estrogen-driven. But giving women a drug that blocks the total estrogen in a person's body doesn't even make sense to me - your heart needs estrogen to be healthy, doesn't it? I'm searching for a healthy, NATURAL replacement for this awful drug. F 59 8 months
1 mg 1X day
7/6/2020
 1  Breast cancer Emotions like a man. Very strange. Never cried. Felt some fogginess also. Legs hurt. Just felt totally different. Can't remember everything. Couldn't think as well. Took 6 months to feel like myself again after taking A half dose of it for nearly 6 years. F 75 5 days
? 1X day
9/20/2020
Email
 1  Breast Cancer Stiffness, numbness, insomnia, anxiety, loss of memory , depression, hair loss, appetite loss, poor vision an hearing, smelling ,tasting, weak, confusion, acid reflux, severe daily constipation, extreme shortness of breath, severe heart raising. Severe bone pain, nerve an muscles, organs hurts. U hurt every day all day an cry uncontrollably. Eyes dry an mouth sore daily. Ur gums feel like you've had several tooth pulled tender to the touch. Ur eyes feel like the sun is burning them. Hot flashes an chills harshly daily. Cramps in hands an feet daily. Dry mouth with severe bad breath an tongue blisters. Sever dry vagina EXTREMELY IRRITATING an PAINFUL. IT'S A LIVING HELL WITH NO END IN SIGHT.😢 F 53 3 months
1mg
4/21/2019
Email
 1  DCIS stage 0 Debilitating joint pain, all joints. Lethargy. Fatigue. Hand numbness and tingling at night. My Oncotype DX score was 0 out of 0 - 100. Recurrence rate was 5%. Oncologist insisted I "needed" the drug. No radiation. He said to stop it for 2 weeks, on day 8 I felt normal. Will never take it again.I don't care if my recurrence rate is the 5% or half of that, meaningless. And at the end of the 5 years you have osteoporosis. F 69 4 months
1 mg. 1X day
6/20/2019
 1  Breast Lumpectomy Had arthritis to begin with but had a steady decline over three years of taking Anastrazole. Have now been told my knee joints are "horrendous" and am awaiting knee replacement. In tremendous pain and having to use walking stick all the time. Moving about like a 90yr old! Now left foot is causing great pain. Just hoping I can remain mobile while waiting for op in UK. Not sure I realised how debilitating this drug is. Blamed myself for being overweight. Would be grateful for anyone's help/comments re pain relief. Do I stop taking it and risk return of cancer? F 68 3 years
1mg
7/8/2019
Email
 1  Stage 1A left breast hormone positive I already have fibromyalgia. I am cancer free due to bilat total mastectomies. Oncologist is prescribing as cancer prophylactic. Being new to all this, I'm scared of the side effects I started only 8 days ago.. How am I to tell the side effects if I have any are from arimidex or a fibromyalgia flair up? F 63 8 days
1mg 1X day
11/5/2020
Email
 1  Estrogen positive breast cancer My entire body hurts. Started with extreme night sweats, told my onc., she told me to switch to every other day for a month so my body could get used to it and then on to every day. From the top of my spine to the heels of my feet I hurt. Can't stand OR sit for extended periods of time, spend a lot of time laying down. I make a point of moving daily to decrease bone and joint stiffness but that literally exhausts me. Does anyone else get headaches? I see my onc. next month - will discuss all of this. I'm glad I found this page! I was starting to wonder if it was all in my head. I spend a lot of time isolating myself because I'm as tired (and embarrassed) of answering "How are you feeling?" and responding that I hurt as the people who ask are tired of hearing it. I feel so guilty and lazy. I'm glad to see that I'm not the only one and I'm not going crazy. This teensy tiny pill has knocked me on my butt! Thank you for listening 😊 F 47 2 days
1mg 1X day
5/27/2018
 1  Breast Cancer I am still suffering from severe side effects due to extra sensitivity to several changes of generic brands of Anastrozole which was not recognised for 2 years. I had Multiple compounding and debilitating side effects due to interchange of these generic brands followed by the most shocking withdrawal symptoms. We are not told how toxic Anastrozole really is. F 76 2 years
1mg
5/1/2018
 1  BC Neuropathy in foot and leg, the most extreme fatigue and muscle weakness. Hip and back pains This drug should not be on the market, it's poison to the system. If you want qualitty of life do NOT take this drug. It's sapped me of all strength, all joy and I got through the cancer, mastectomy with no trouble but this drug has ruined me. I only took it for month till all the pain came but all the SE's are still with me after 3 months. I can hardly function for muscle wastage and weakness. The worst thing I ever did was take this F 66 2 weeks
1X day
6/5/2018
Email
 1  Breast Cancer Extreme Traveling Pain,Numbness,Can't Sleep,flu like symptoms,Stabbing Random Pain, Inner Bone Pain,Nerve Pain Took Arimidex 9 years ago.Effects still come randomly. 17 months ago went on whole food diet, seemed to trigger it.Sounds crazy, just a few days after changing eating it started.It made me recall Pain Management Dr., UCSF said months after pain first started years ago, wanted me to lose weight (guess due to severe knee pain) though i was not over weight when I returned having lost weight due to healthy changes he said "don't get to healthy the pain will get worst the stronger the immune system the worst the pain WHAT!? (I wonder, Arthritis patients giv'in steroids to suppress I.S. that less'ins pain? even though it all but kills I.S).I'veThought alot about meds nutrition ect for 10yrs,it all stinks! excluting nutrition.I knew in my heart it was Arimidex but Oncologist UCSFsaid "no" and also told me "the pain can't be that bad" (hands r numb from typing) We've been poisoned! This is my life.Undiscribable traveling pain. Sounds crazy trying to describe. Drs will not prescribe anything close to relief, due to"Opiate scare" wish looked at us individually,not bunched together.Took Dilaudid 9 yrs ago,worked great,then pain decided to leave, I did'nt need them anymore, period. But God knows I need them again.We only have eachother Was told at one point I had Carpel Tunnel went for operation Dr.listened to symptoms"u don't have C.T.it's Arimidex" I cried hearing anyone admit."OH GOD! It's a crime! I wait for class action to get Pois F 57 3 months
1mg 1X day
7/3/2018
Email
 1  Yes All se listed. Could barely walk 1/2 block Such joint pain and constant sore throat. Got frail. Voice weakened. F 68 1 years
?
8/9/2019
 1  Stage 2 BC Mood swings, fatigue, joint pain (as in ALL joints), neck, back and hip pain, muscle pain, hair thinning, weight gain (25+ lbs), absolutely no sex drive, panic attacks, and just feeling run down. I hate the SE of this medication. Through God's grace I have survived the cancer. Made it through chemo and radiation with not many problems but this medication is a completely different story. I've been on this and Lupron for almost 2 years and feel like I have aged 10+ years in that time. I am unable to work because of the back pain and my abdominal wall has become paper thin which makes my stomach swell up after any length of time on my feet. I have recently been approved for disability. I now am going to pain management which just means more pain pills. I dont want to have to take any more medication. My blood pressure is high and I have to take medication to control that. I have severe anxiety accompanied by horrible panic attacks and am now in Zoloft for that. They are saying it's PTSD...but from what? Ugh, so frustrating. I'm thinking of going off the medication all together. I've already started taking the arimidex every other day instead of daily and it seems to help some. I can definitely tell a difference on the days I dont take it. I'm not sure if the SE are from the arimidex or the lupron as they are both awful and have very similar SE. I'm so thankful I stumbled upon this site. Now I know for certain it's not me that's going crazy...it's the medicine. F 38 2 years
1x day
12/30/2018
Email
 1  Stage 1 breast cancer Irratible, hot flashes, achey feeling first month on drug progressing to painful knees and shoulders, sharp random stabbing pains in feet and hands, awful heavy feeling like weights on my shoulders and cracking knees on standing and walking. After finding this site and reading others experiences was easy decision for me to stop as do not like the crippling side effects. Haven't told doctor because know he will just wanna put me on something else with same awful side effects. F 66 3 months
1 mg 1X day
11/17/2022
 1  Breast cancer Horrible joint pain, especially in my shoulder on surgery side. Inability to use my shoulder at times. This pain is far beyond “take a Tylenol” my nurse practitioner recommends. I am unable to drive because I have a stick shift. After speaking with a pharmacist, I was told this is one of the side effects.I'm not taking it for a month and see if the pain lessens. No benefit from the drug if your life isn't worth living F 66 4 months
1 mg 1X day
1/17/2023
 1  Breast Cancer Stage 1B I only took Arimidex for 30 days, the side effects got worse by the day - trouble sleeping, when I did sleep didn't feel rested, fast heart beat, anxious, jittery, nervous. The fatigue set in. Felt dizzy and nearly fainted twice (my son caught me before I could fall). Started sleeping 12-14 hours per day, could not stay awake. Dozed off at stop lights while driving. Had to stop driving and got to the point where I couldn't go to work. I had other symptoms like hot flashes but those I could take. Did 2 1/2 years on tamoxifen which was much easier for me. Still had side effects but I could handle them. Had to stop tamoxifen due to irregular vaginal bleeding. My oncologist didn't feel comfortable having me continue. Can't take Arimidex and function at all. My overall health is good, had blood work, thyroid ultrasound, etc. The side effects I experienced was definitely due to Arimidex. Felt great before taking this drug and started to feel better a week after stopping Arimidex I am just postmenopausal so perhaps this is why the side effects were so severe. F 53 30 days
10mg 1X day
6/12/2015
 1  Breast Cancer I have just had a lumpectomy and now my doctor wants me to take Arimidex. I have bad side effects to most drugs and try to do things holistically. Tumor was 1.5 cm E& P + but two nodes negative. No family history. I am VERY active and am concerned how this drug will effect my quality of life. The Doc SHOVED a 2 week sample pack at me today and said I should at least TRY it. One thing that no one seems to address here is the sexual aspect of this drug. My husband and I are very sexually active and this concerns me. I am thinking of just having radiation and not taking this drug. Sure I want a long life but I think QUALITY of life is more important to me .. Please if there is anything women can share with me about all this I would greatly appreciate any advise F 67 1 days
mg 1X day
8/6/2014
Email
 1  Breast Cancer Stage 2a Bone pain, neck pain, leg cramps, dizziness, nausea, irritable, vision changes and fatigue. F 48 45 days
1mg 1X day
11/14/2014
Email

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