ARIMIDEX Reviews (ANASTROZOLE)

Average Rating: 2.5 (1431 Ratings)

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 ANTINEOPLASTICS AROMATASE INHIBITORS

 Type: Rx Drug

  

ARIMIDEX  (ANASTROZOLE):  Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1995-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ARIMIDEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ARIMIDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Breast Cancer Stage 1 Joint pain in hands, feet, and a sometimes all over feeling of ache. It's hard to pick up my water glass in the morning. I've been on it for 5 months and have gained about 8 lbs. even though I've been working out. I've also experienced sleeplessness, hot flashes, night sweats which I also experienced when I was on Tamoxifen. I was on Tamoxifen for about 11 months when I was experiencing severe memory loss. After going off the Tamoxifen for 1 month, the memory side effects went away. My doctor switched me to Arimidex and I've been on it for about 5 months. I've read several of the other comments about others wanting to go off of it because of the side effects... I'm not sure I really want to risk the alternative, but it's definately crossed my mind. F 40 5 months
3/12/2006
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 3  breast cancer Awful, awful aches and stiffness in the knees and foot joints. Tingling sensation in the feet. All of these symptoms seem to be getting worse. Sometimes I can hardly walk in the morning and by day's end, my legs have had it. Often there is a burning sensation in my feet. Notice the stiffness is moving to my elbows, arms, and hands. Forget deep knee bends. Don't have the energy I once had nor much enthusiasm for anything physical. Almost suddenly about 5 months ago I started gaining weight. I live where it is extremely cold in the winter with lots of snow. Find myself more leery about walking on the snow for fear of falling. Notice I don't climb on a chair like I use to to reach high places. Am inclined to believe the cure is nearly as bad as the disease. F 64 3 years
3/18/2006
 3  Breast Cancer I am experiencing an intolerance of alcohol - that is right, no more wine, beer, or hard drinks. Symptoms include severe headaches either immediately or the next morning (after only 2 teaspoons), neck ache. I've told my docs but they have never heard of this side-effect. Anyone else???? Otherwise, feeling well. I have fatigue, but that might be because I have recently (nearly a month ago) finished my accelerated partial radiation. No bone pain. F 59 65 days
10/17/2006
 3  DCIS with infiltration osteopenia, aches and pains, high cholesterol, fatigue, vaginal dryness, hot flashes, UTI's I have just discontinued Arimidex after being on it for 3 years following 2 years on Tamoxifan. I had virtually no side effects, other than hot flashes on Tamoxifan. With Arimidex, everything else kicked in. With Tamoxifan, my bone density was 109% of normal. After 2 years on Armidex, I had osteopenia. The foot, leg and back pain are virtually constant after any relaxation at all. They do work out after exercise to a degree. I walk over 3 miles 3 to 4 times a week. Since being on Arimidex, I have developed a weakness in my right leg after walking about 1-2 miles resulting in a kind of 'foot drop' while walking. After a neurological workup, where a small, benign brain tumor was discovered, it is theorized the the tumor is in the wrong place to cause the problem and the feeling is that the leg weakness is a side effect of the Arimidex. I have been off the medication for 3 days now and am anxiously waiting to see if my leg weakness and the other symptoms will resolve within the next few w F 64 3 years
9/11/2006
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 3  Breast cancer stage 2/node Joint stiffness and aching; drenching hot flashes; memory problems; inability to concentrate F 48 3 months
8/22/2006
 3  inv lobular bc/mast. rt 1 node I have been taken it for 6 month and I notice increasing stiffness, bone pain, hot hot flashes, tremors,and itching. I also bruise very easily. Does anyone else have the itching and bruising? when I first took arimedex I didn't have any symptoms but gradually they have started. Now my fingers, hands, arms, neck, shoulders, and hips all ache. I thought I was just getting old. I looked up symptoms because of the bruising. I'm soo glad to have found this site. F 53 6 months
10/2/2007
 3  IDC, Stage I, lumpectomy, no nodes Excruciating pain and swelling in both wrists, now experiencing similar pain in knees, insomnia, weight gain, loss of libido, irritability, profuse sweating when exercising, hot flashes & night sweats abating somewhat. The wrist pain began in my left hand and has now appeared in my right, and since I'm right-handed, it's beginning to interfere with my ability to do my job. The knee pain is strange--I only feel it when I touch a certain place on the outside of the knee, and then I yelp in agony. I experience the usual creakiness, groaning when I get up from a chair or out of bed. I am very fit, exercise vigorously every day, and eat right, and I've never had any joint pain before. Even though the night sweats and hot flashes have abated somewhat (not completely), I rarely sleep more than 4 hours a night. What's the minimum effective time to be on this drug? I hate it. I have a one-year post-radiation mammogram next week. F 59 11 months
10/10/2007
 3  BC Hot flashes, joint pain everywhere especially after sitting in one position for any length of time. Weight gain which I will try to lose. Thin hair, mood swings and swollen ankles. I wish these doctors would read this website. They have no idea (or don't believe us) as to what this drug causes. Does anyone taking Arimidex have swollen ankles besides me? If this drug will keep the cancer away I guess I will have to tolerate it if I can. F 62 10 times
10/10/2007
 3  Breast cancer stiff finger joints, swollen hands and feet especially in the morning, no sex drive, dry vagina. I would like to recomend alternative medicine for the lack of energy, tiredness and depression that so many of you are feeling. Try to find a good alternative healer who could restore your energy levels. It worked wonders for me, I continued to work (about 9 hours a day), take care of my family, learned how to swim (can now beat my husband any time) and finished an MBA and I wasn't even tired at the end of the day. If anybody has found a remedy for the lack of sexual drive please share it! F 47 2 years
9/14/2006
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 3  BC recurrance in sternum I feel tired, very tired all the time. My joint pain is very severe and the bottom of my feet hurt, particularly in the morning. I have water retention upon wakening, irritability, frequent and potent hot flashes, and have absolutely no interest in sex. I have found, that if i have the strength to excercise, the joint pain seems to diminish. I was never one to go to bed early but now, after working all day, i need to be in bed by 9 or 9:30 PM just to get through another work day. I guess i am so grateful for the expert surgery i had and just to be alive, i will put up with anything. I really hope this medicine is working because my oncologist thinks i will be on it for a very long time. F 58 8 months
8/24/2006
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 3  breast cancer stage 1 I was taking aromasin first and was practically crippled and could hardly stand up. The arimidex is better but I still have a lot of joint pain and muscle ache. I also am having trouble sleeping. I wonder if this joint pain goes away when one is finished with the arimidex. It would be nice to look forward to that. F 60 1 years
4/19/2006
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 3  EARLY BC, LUMPECTOMY AND RADIATION Hot flashes at first which are some better, but in the last 3 months am having moderate to severe foot and leg pain, pain in upper arms, extreme fatigue during last two weeks, swelling in feet, cannot walk even short distances, considering getting handicap permit, will see Onc in two weeks to talk this over, I also felt better after radiation than I do now..also last mammo showed new calcification, will have re-check in 3 mos. Never told about these side effects, only the hot flashes...found this web site on my own, some consolation to know I am not alone with these problems I also find that riding a stationary bike helps pain some, walking very difficult and becoming more daily, bone density last year was good, will have another in a few months, will see if any changes. Father, Paternal Grandmother and Maternal Grandmother all died with some type of cancer...feel like I got to keep going with this, but sure does hurt, cannot enjoy the grans...life is pretty much work and home, don't feel like anything else... F 55 1 years
4/21/2006
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 3  stage 1 invasive, lumpectomy radiat I feel so old. Insomnia drives me crazy..extreme fatigue, stiffness. I have been thinking it was fibromyalgia, which had been getting better before the cancer. I have been on it for 2 years, and didn't realize that it may be the arimidex that is making me feel so horrible. I had very small lump, early detection, no lymph node problem, my mother had breast cancer, so the doctor never told me about side effects. but after reading this site, I am beginning to think of getting off it and being able to sleep and walk again! I will take my chances with the cancer. Oh yes, have gained 30 lbs too! I hurt too much and am to tired to exercise. I am taking a chronic pain class to learn how to deal with all of this. My knee is starting to hurt now too. F 64 2 years
8/28/2006
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 3  stage 3 breast cancer mastectomy Legs very stiff in the morning and painful to walk trouble sleeping Have been taking for 1 year and I am also worried about my feet F 46 365 days
11/11/2006
 3  Bi-lateral breast cancer At first, extreme bone/joint pain all over, especially feet and hands. My Onc suggested I go off it for 1 month and try again. For some reason he said that works for a lot of women. When I went off, stiffness definitely got better but did not go away. When I went back on it though, it did not get any worse. There are other drugs out there. If you're miserable, ask for something else. F 51 2 months
11/22/2006
 3  stage 3 breast cancer mastectomy Legs very stiff in the morning and painful to walk trouble sleeping Have been taking for 1 year and I am also worried about my feet F 46 365 days
11/11/2006
 3  Stage II Breast Cancer, Her 2 pos Pain and stiffness of joints, especially my mid back, shoulders, knees, hands, & feet A pressure feeling - like I used to have before my period. Frequent UTI's and getting up 6 times a night to go to the bathroom. Not sleeping well, trouble getting to sleep due to anxiety - and even after every trip to the bathroom! Very "foggy" thinking at times - forgetting information for the first time in my life! Getting all mixed up with things I normally do! Feeling (and walking) like I'm 90 years old. My husband found this site - in the middle of the night one night, as I lay in bed "reading" and trying to relax enough to get back to sleep. He told me I wouldn't believe it - that other women sounded just like me! That all the symptoms I was having were mentioned by others too! It made me feel better to know it was the medicine causing my issues - rather than possibly another medical condition, as I was beginning to fear. So, thanks to all who wrote! I am planning on staying on arimidex and just trying to hang in there with all these issues . . . hoping it will help prevent an occurrance, especially since my doctor says I have a very agressive form of breast cancer. F 54 6 months
11/29/2006
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 3  Breast Cancer Stage 1 - Lumpectomy Fatigue, memory loss, inability to concentrate, moodiness, depression, minor joint stiffness, occasional swelling, aching feet and legs at night. Hot flashes first 6 weeks on medication. Tamoxifen was not an option for me as I had history with blood clot. I was somewhat relieved to read about memory issues with others. I have been in my manager position for 11 years and recently have felt unable to juggle the many tasks I normally handle with ease. The hair loss, aging dry skin, other aspects I find easier to live with but I really love my work and this inability to function at my normal level is seriously depressing me. I had my yearly follow-up mammogram and all is clear but if moodiness continues will seriously considering whether to continue with the arimidex. Thank you everyone for your postings I was beginning to think my declining ability to think on my feet was due to my approaching 60th birthday but now realize I need to discuss this with my doctor. F 59 8 months
3/25/2006
 3  Diagnosed with LCIS - prevention Hot flashes were bad the first couple months, but now the joint pain is moderate to severe; knees, feet, ankles, lower back. Legs ache and keep me awake at night. Also memory loss...thought it was just me until I read this! No sexual desire... Concerned about long term damage after the five year protocol. Wonder if it's worth the side effects. F 56 6 months
8/21/2005
 3  breast cancer joint pain for first time in my life (debilitating in the morning); decreased sexual desire; dryness everywhere Over the counter GLUCOSAMINE really helped my joint pain. I take 1000mg at bedtime and 500mg in am (larger dose at night seems to help with am joint pain). REPLENS helps with vaginal dryness. ASTROGLYDE helps with intercourse. I worked out yesterday and this am did not have shoulder pain. Hopefully I'll see a pattern that exercise helps joints. F 48 8 months
8/21/2005
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