ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Acne Severe osteopenia,sjorgen's like disorder,chronic blepheritis,joint,muscle and tendon problems,hormonal problems (such as thyroid)low iron,fragile/thin skin and wrinkles. Do Not take this Chemotherapy drug. It will ruin your life. I had 3 cysts the color of my skin. I have never been the same since. The doctor told me I would only have dry skin and body. I had only dry lips while on it till the last 2wks of tx which I stoped the med due to not feeling right. This poison continues to work even after you stop the med. It causes cell death, hormonal problems. I continue to still live with theese issues after 1-1/2. I am now on a drug to combat my chronic inflmation state with a drug that lupus pts take. My Osteopenia may or may not improve. My autoimmune thyroid disorder will always be a constant battle. To top it all off I still have thoose 3 cysts, they never went away. to the women who wrote about hormonal problems you can contact me and anyone elese who has questions or needs help F 32 8 months
1/23/2010
Email
 1  To clear my skin Yes I have clear skin now, with the occasional spot. But I have fell into a deep depression, I feel lost in so many ways I was never a down or deppessed person on the first place even when I had spots I was OK yes maybe some days I would look at my skin and think maybe stay into because I wanted it to look better before I went out but I was not deppessed. Yes I got like every other side effects from dry lips, but the depression has hit me hard I have been off the Tablet for 3 months nothing seems to be getting better in a way maybe worse I am so worried and scared I wish I never went on this drug and was just normal, I hate my whole life and the life I am living can't even be called a life because it's not This Tablet messed up my brain I am depley depressed F 15 5 months
50
6/30/2015
 1  moderate acne I have suffered with acne ever since i started high school and i have always been so self conscious and been ashamed of myself for the way i look. I have always known accutane is a dangerous drug to take but it was a last resort as everything else i tried didn't work. I was very dry but had no side effects until 3 months into my treatment. I got pink eye and it wouldn't go away even with antibacterial eyedrops it was still quite bad. My dermatologist told me it was very unlikely the accutane would be causing this. I went off accutane as i also started getting head aches, even after going off the accutane my side effects are now continuing even worst, i have terrible sinus pain, back pain, head aches, droopy/puffy eyes, i have had bloating and this is all happening once i have gone off the accutane which is really scary. 1 month after being off accutane these side effects are still bad, i'm glad i wasn't on it longer and on a higher dose. The dermatologists àre making mega bucks off this medication and they won't tell you how bad for your body it really is. The number one cause of disease is dehydration and that's what accutane does it sucks your body dry. These side effects are so much more common than you realise and the list goes on and on of possible side effects you may receive while you are on the medication or in a lot of cases like mine once you come off it aswell. My mum and i have spent so much money on accutane and even though it has made my skin slightly clear F 19 3 months
20mg
11/8/2015
Email
 1  Acne Took this drug from HELL when I was 22 and I'm 37 now. It has ruined my liver and kidneys. Many digestive problems. Depression, burnout,anxiety,suicidal thoughts. The mental stuff I manage through homoeopathy. Long term ligament and tendon dysfunction. Neurologically never the same. The list goes on. Do not take this drug. Acne is a symptom of an underlying problem. Usually related to toxicity or hormones which can be corrected by homoeopathy. Please do not take this drug. You might be one of the unlucky people who end up struggling for the rest of your life. I'm studying medicine now and I might have to stop because of this. F 37 7 months
40 mg
5/6/2016
Email
 1   Never tried it but I just read a lady's story she said it was a drug from hell all the side effects was horrible.I lust looking 4 something to help my ugly scared up face xI use robe flawless wen tried coming suicide before F 38 1 days
7/29/2016
 1  Acne Joint pain...tingling and numbness in fingers...back pain...etc. This medicine has turned out to be the worst thing I could have tried. I was desperate to try something because my skin was terrible!!! My dermatologist said this would be best for my skin condition. I know I needed something but I'm certain that this was the wrong medicine for me. I've now been off it for over 2 months and the side effects that I was told would leave are still lingering around! I just want to be able to use my hands like I use too...I want to wake up without numb fingers every single day...I could go on and on...I would advise anyone considering this medication to consider other. F 35 5 months
40 MG
11/4/2016
 1  Acne It didn't work well (had to take 2 courses within a 5 year span, & each time, my acne came back), & 3 years after finishing the 2nd course, I was diagnosed with Multiple Sclerosis. This drug is indeed poison. F 28 6 months
2/25/2015
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 1  Mild Acne During treatment, experienced back pain, ankle pain, dry lips, poor night vision, skin sensitivity to sunlight, and muscle pain in forearms. One month after course ended, experienced bloating, gas, diarrhea, dry eyes, dry hair, pale skin, dry skin, deep wrinkles, hair loss, brittle nails, fatigue, loss of smell, loss of taste, pain all over body, numbness and tingling in hands and feet. All of the above side effects continue 5 years later, as well as tinnitus, hearing loss, vision loss, headaches, premature menopause and more. Do not take this drug! It may cure acne, or it may not, and you can end up with permanent side effects which will affect your ability to function in life. This drug is used as chemotherapy in lower dosages than what is being prescribed for acne. Side effects during the treatment are bad. Side effects after the treatment are even worse. The side effects continue to get even worse as you age. F 35 6 months
40 mg 2X day
7/13/2015
Email
 1  Mild acne Aging skin. Dry eyes. Severe depression.thinning hair and skin. Please Please if you are reading my comment, i'm begging you yes i'm begging you, DO NOT TAKE the poison isotretinoin ( the active ingredient in accutane, curacne etc ..) İt completely ruined my life, i was a happy and a normal person and it turned me into a depressive, angry and a sad person,it killed my creativity, my imagination, my love of life.. İ'm not even talking about the physical effects yet like the thinning skin, my skin became so thin and crepey that i Can see clearly my veins through it, no matter what oils, butters, creams i put on it, it will never smooth out the lines and wrinkles, it became like a lizzard's skin. My hair also was affected by this poison, i had a very beautiful soft and tick long hair, my tears are falling while typing this, my hair changed completely After taking the poison, it became so thin and weak, ten years After accutane, my hair still ugly, it's shedding continuously like in a vicious circle. The Doctor or murderer who prescribed this poison to me didn't mention anything about the side effects, i trusted her because i was innocent and naive and back then i had no access to internet or to any kind of information. So i blamed myself long enough to realize that it wasn't my fault. İ pray God that whoever invented this horror, whoever prescribed it including my Doctor will be judged and punished for destroying lifes. İ'm trying to have a normal life somehow by practising sport, reading, praying a lot too F 34 1 years
20
8/19/2019
 1  mild/moderate acne DRUG RUINED MY LIFE. SUICIDAL EVERY SINGLE DAY 5 years later. All the tissues of my body have been irreversibly damaged - brain, nerves, muscles, joints, tendons, ligaments, skin, hair, bones. All in severe agonizing 24/7 pain. Feel like I'm burning in hell constantly, was disabled by age 22. My father being a doc sent me to his derm friend, who convinced me that low-dose accutane was 'safer than long term antibiotics'. He said all the stories and press were unfounded in science literature and not linked to accutane. Convinced me to take low dose. Was ok for first 3 months treatment, then developed ache in ankle. He said it wasn't related. Mild hair shedding. Became more depressed. Stopped treatment early, 5 months in. 5 months after I stopped, ENTIRE BODY FELL APART, severe brain damage/borderline brain dead, confused, barely able to walk or stand, pain spread to EVERY SINGLE joint in entire body with horrific cracking, skin ruined, facial fat atrophy, hollow eyes, I look 20 years older and feel 90. Developed parkinson-like tremors, suicidal depression, wished for death, burning nerve pain like I'm soaked in acid. All this happened AFTER I stopped. This is the most horrific coverups in modern medical history, a genocide of youth. I am 100% sure the literature showing 'no link' between IBS, depression, and accutane use is completely fabricated. SO MANY PEOPLE INJURED BY THIS. Even in my normal life I know people damaged by it. Completely disabled have been mostly bedbound for 5 years I am in the process of applying for euthanasia. I cry and am severely suicidal every moment of the day. I had a great life before this and was studying to become a dotor, 4.0 student, athletic, happy. ROCHE, YOU WILL BURN IN HELL. F 27 5 months
20mg 1X day
10/2/2019
Email
 1  acne Extreme depression, suicidal thoughts, confusion, anxiety, hallucinations DO NOT GIVE TO TEENS Ruined my life Nearly took my life F 15 6 months
1/22/2016
 1  Acne F 19 100 days
30mg
12/22/2019
 1  Acne Cracked lips and ends of mouth, dry skin on face, pain on heels, knees, back pain, Rectal bleeding, mild rash on arms. I cannot walk or stand properly due to pain in heels of feets, back and knees. Cannot walk for long time and have pain while passing stool. F 25 4 months
2 tablets
1/5/2020
 1  Chronic Cystic Acne Loss of almost all scalp hair, still losing it, loss of eyebrows, lashes and body hair, change of colour, texture, thickness, elasticity of hair before it fell out. Conjunctivitis, permanent eye pain, problems with night vision, dry eyes, back pain, scalp pain, earache, joint pain, cracked bleeding lips, strange ridges in finger and toe nails. TOXIC POISON. My dermatologist repeatedly recommended this to me, as a safe natural vitamin A product which would cure me in a short time, unlike long-term hormones, and the worst I could expect was to feel uncomfortably dry. I asked him 2-3X about any effect on my (beautiful, thick, curly red hair) and he assured me the effect was just temporary dryness and that as soon as I stopped taking Accutane all side effects would cease. Every time I expressed concern he would say to me : "Who's The Doctor??" I agreed to try it. After three months I stopped and that's when the hair loss started. I had never had a problem before and was not on other meds. What all the experts I subsequently consulted called Telogen Effluvium became chronic and never stopped. The doctors all denied it was related to Accutane! They're still prescribing it. Hoffman LaRoche isn't suffering, my dermatologist (now comfortably retired I expect) never suffered, Health Canada who approved it never suffered. They're all responsible for destroying my life and clearly others' but didn't pay even as much of a penalty as someone who steals a loaf of bread to keep from starving. Dr. L. S. in Montreal, I pray every day that YOU in particular rot in hell. If your doctor suggests you take this garbage, ask him/her first if they are willing to pay for your wigs. I'm thinking, no. F 59 90 days
40 mg 1X day
9/26/2020
Email
 1  Polycystic Acne I took Accutane many years ago...13 years ago to be exact and I still suffer from cracking joints, chapped lips, dry scalp, dry skin... the list goes on. The cracking joints are embarrassing as I'm only 34 years old. I've waited years for it to stop and it has not. I'm glad I found this thread. I'm going to try taking vitamin D and see if it helps.... I'm seeing a Dr now to try to get to the bottom of it. On top of all of this....I Still Have Acne F 21 6 months
Don't reme 1X day
3/13/2021
 1  Severe cystic acne I developed severe cystic acne in my 20s and by the time I was in my early 30s I tried every antibiotic and medication there was. I was put on Accutane for the shortest course of 15 weeks. I developed severe headaches, totally debilitating. I also had the dry skin and eyes. It wasn't until several years later that I started developing the side effects. I lost my eyebrows, hair on my head thinned, my menstrual cycle ceased permanently so I was never able to have children, elevated liver enzymes, degenerative disc disease which has now developed secondary scoliosis that has progressed to the point that I cannot walk or even stand unaided. I developed major depressive disorder with suicidal ideation, generalized anxiety disorder with panic attacks. These conditions have lasted until now and I am 54 years old today. No Accutane cleared my acne for good it also ruined my life. I eventually lost my business and had to go on disability because of the severe back pain from the DDD and emotional problems. Please take this medication with serious forethought. F 54 15 weeks
30 mg 1X day
9/13/2020
Email
 1  Nodule acne I have struggled with weird skin issues for years. Dermatologists always prescribed topical meds and nothing worked. I have itchy inflamed knots under my skin. Mostly on my face and some on my neck. They never fully go away except when I took steroids for another skin rash condition caused by allergy to another med. my new dermatologist put me on Accutane confident it would cure. 7 months nothing. I had horrible skin, new eczema developed, depression, horrible peeling lips, and I started feeling lethargic. She wanted me to keep taking it 10 months but I don't have insurance and it was so costly. I had to quit. I felt it was doing more bad than good. Now I've been off it a month and my health is declining. I got a bad yeast infection, vomiting, lethargic, dizziness, massive weight loss, trouble eating, and my skin is even worse on my face now. DO NOT PUT THIS TOXIN IN YOUR BODY Would love to know if anyone else has similar health issues now. What has helped? I am going to see a functional doctor next. F 38 7 months
1X day
4/15/2022
Email
 1  cystic acne I started getting mild stomach issues towards the last 2 days of taking accutane. i stopped it immediately but it was too late. The permanent damage its caused to my body ruined my life forever. A few months after I stopped accutane, my digestive issues got 100x worse and I developed new conditions. I have since been diagnosed with inflammatory bowel disease, autonomic dysfunction, POTS, peripheral neuropathy, and degenerative disc and joint disease. I am disabled now. Several years later and I am still disabled, getting worse every year. and this was from a LOW dose. This stuff is pure poison. This will ruin your life and all the serious effects happen after you stop F 27 3 months
20mg 1X day
6/24/2022
 5  Acne dry lips I had cystic nodular acne on my face, back, and chest. I've tried every acne medication under the sun! So happy I've purchased Accutane (Qacne365). It worked great and I could tell a difference within a month of using it. It's been 3 years since I took it and I'm still all clear. I would recommend Accutane to anyone with acne. M 24 60 days
60 1X day
9/13/2022
 5  cystic acne back acne worked great - but did have dry skin and very dry lips. Please check out my full review under Zenatane. https://www.askapatient.com/viewrating.asp?drug=202099&name=ZENATANE M 16 6 months
30 1X day
9/8/2023

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