ALLOPURINOL Reviews (ALLOPURINOL)

Average Rating: 3.0 (212 Ratings)

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 ANTIGOUT

 Type: Rx Drug

  

ALLOPURINOL  (ALLOPURINOL):  Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Allopurinol works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.   FDA Approval Date: 1986-10-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ALLOPURINOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ALLOPURINOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  gout Fatigue, dry eyes, nose and hair. Multiple joint pain. Inability to wear shoes comfortably. Well controlled uric acid from 10 to 6 F 69 10 months
150 mg
7/27/2014
 5  gout No side effects. Have been gout free for nine months. Prior to allopurinol I was having gout attacks every three to four months. M 34 9 months
300 mg
12/16/2011
Email
 3  Gout Body pain. Dizzy. No more gout. The side effects are not as bad as the gout. M 37 9 months
2/27/2005
 5  Gout Tired initially for first 1 month or so and then body fully adjusted to it. Also had 3-4 to be expected attacks initially as a direct result of Allopurinol cleaning uric acid deposits. Since then my 1 year long non stop Gout pain has 100% disappeared. I rate Allopurinol higher than so called God! I will take it for rest of my life with pleasure. From some of the comments here I see that some are absolutely clueless about AlloPurinol. Give Allopurionl a chance! You can't undo decades of blood uric acid build by taking AlloP for just few weeks or months! Tough it out initially and you will be rewarded. AlloP for life for me! ALLOPURINOL I bow to you literally!!!!!!!!!!!! M 36 7 months
300mg 1X day
7/18/2010
 3  Hyperuricemia On higher dosage, I developed irritable bowel symptoms, like intestinal cramping and loose, urgent stools three to four times a day, followed by stomach ulcer symptoms (constant burning, gnawing feeling). Lost 27 pounds in three months. I started Allopurinol due to very high uric acid levels. I did have a few gout attacks over the years, but it was not constant. Still, high uric acid can lead to other health issues. My doctor started me on a low dosage (100 mg per day) and increased over four months to 400 mg a day. My uric acid level came down to normal. A month after the increased dosage, I became very ill for six weeks with the symptoms I've mentioned. I could barely eat or function. I had a slew of blood tests, stool tests, barium swallow and abdominal ultrasound to find the source of my G.I. issues. All test were normal. Doctor cut back the dosage to 200 mg. a day and after six weeks of suffering, my symptoms resolved. My doctor is still hesitant to admit that the higher dosage caused these issues, but I am convinced that it did. I'll continue taking Allopurinol at this lower dosage. Hopefully, I'll have no further issues. F 61 7 months
100 2X day
8/5/2018
 1  gout Complete fatigue, intense joint pain and suicidal 5-month, acute gout attack in both feet that encompassed the entire foot and extended half way up the calfs in both legs. Relentless red/purple swelling in the feet, no sleep for months and thoughts of suicide due to lack of sleep and unbearable pain. The doctors said that this was the worst gout they have ever seen and published photos of my left foot (the worst of the two feet). I have friends that take this drug and they are doing fine. I must be allergic to it. I have a pain tolerance that you wish you had and 5 months of Allopurinol screwed me up forever. The damage done to the connective tissue in my feet may never heal. Poison...at least for me. If you have gout make sure you go to a specialist. Most docs are morons when it comes to gout and will push you down a slippery slope. I am taking Uloric now and it seems to be the real thing....urate level at 6.3 mg/dl in 3 weeks. Make sure you have colchicine and indomethecin that you can take if a severe attack happens...I did not even know of these drugs and when the intense attack happened I was not prepared. By the time I was prescribed these drugs (3 months into the bout) they did not even touch the pain. One good thing....I am now completely immune to pain of any kind. That gout bout burned out any pain receptors. M 50 7 months
300 mg 1X day
8/22/2010
 5  Gout initially general malaise but that was probably the gout effecting me than the zyloprim. Once the gout cleared all seemed ok. Scary side effect is erectile disfunction. Onset about 4 months ago. Taken allopurinol on and off since 29. Cycling with me getting an attack, colchicine to kill that off, then allopurinol - usually 200mg. Usually then after 7 months of no attacks I (hitherto the most recent attack that is) would drop the meds, thinking I could 'boof' it out and invariably I'd be hammered with another attack within 12-18 months - rinse and repeat. Now I aim to stay on allopurinol permanently. Worryingly I've noticed erectile performance has been severely affected in last 4 months whilst on 300mg-very embarrassing at times and no good for the psyche. Only meds I'm on so if it's meds that's it. Never ever had ed b4. I've put on weight but at 85kg and 180cm I'm not that obese. Can get an erection but not nearly as readily as before. Once a week now if lucky. Use rowing, spin machines but always have before without having been so drastically effected. It's like things are being heavily repressed rather than totally blocked. After today's celebrations (Australia Day) I'll drop the meds for a few months and see what happens. Then start and stay around 150-200mg as that was ample b4 and never had ed effects. Allopurinol also is beneficial for benign prostate enlargement so perhaps that might explain things. I don't have that but there might be some interactions happening down there. M 45 6 months
300 1X day
1/25/2014
 4  Gout Slight burning during urination. Dry mouth. Will have to take it for the rest of my life. Looks like I'm another sucker of the medical establishment. M 34 6 months
9/24/2005
Email
 4  Gout My side effects are not very severe. I am a little more lethargic and may be a little drowsey. Its hard to gauge. Started on 100mg and worked up to 600mg. My UA is around 4 now. Missed a day and was 8 so it works. On it about six months now and have had plenty of gout since starting. Its getting less frequent and my lumpy knuckles are gone as are the white lumps in my ear lobes so I presume I am losing MSA crystals. I'm on baking soda too. Going to reduce to 300mg and see if that keeps safe level. M 52 6 months
4/8/2009
Email
 3  Gout I have had a burn-out with depression and it was well controlled with a daily dose of Cytalopram. Started Allupurinol daily 100mg under "protection" of NSAID and colchicin. Dose is now up to 300mg daily. Had to highten the dose of antidepressant with every dose change of allupurinol. Joints feel fine now. Does Allupurinol have depression as a side effect or does it interfere with the drug cytalopram. M 41 6 months
10/2/2007
 3  Acute attacks of Gout Shortness of breath is the primary but have been lethargic since I began taking it and have unexplained weight gain. My guess is that the slowdown in my daily activity has brought about the weight since my appetite seems about the same. I had a triple by-pass and was never this short of breath. This medicine worked great for Gout but I can no longer stand the side effects at 300mg/day. I am going off of it for a while to see if the side effects diminish. M 51 6 months
7/19/2007
 3  For high ua Rash,excessive sweating. M 27 6 months
100mg
5/4/2014
Email
 1  Gout Breast tenderness enhanced breast under nipple Reduced testosterone nose stuffed up a lot Did get rid of.my swollen feet and gout but at what cost M 80 6 months
300
5/15/2020
 1  gout Dry eyes. Red around rims and lids eye doctor said I had ulcers on my eyelids. Very sensitive to light. Very vivid nightmares. My mom wakes up every time she sleeps in a panik. She says she is really seeing all this. She is full control of her mind but this is scaring her. She also has an itchy rash under her skin. I havent read all your comments yet. But if any feels they are having bad dreams they have never had before or visons in thier sleep please email me F 86 6 months
300mg
7/15/2012
Email
 5  Gout / High Uric Acid 300mg/day. No major issues and no more gout! Possibly feel more tired during the day. Will follow advice of other users and try taking it at end of day instead of at breakfast. M 38 4 months
11/24/2009
 4  severe gout in both feet intermittent stomach ache. frequent headache. Overall ok. I am 43 years old...and suffered the past 15 years with gout pain in my big toes. Going back about 6 months ago i would get pain throughout my whole foot that would basically cripple me. And for no apparent reason as far as diet went to avoid gout triggering foods. I had spent years taking Pro-gout and Colgout tablets which were fine and my attacks would subside within a couple of days. BUT i wopuld suffer terrible stomach ulcer pain and cramps due to it. 4 months ago my doctor did blood tests, and due to very high uric acid levels he put me on a 5 day course of Prednisolone which eased me into the daily taking of 1 Allopurinol tablet. The Prednisolone was fantastic and i suffered NO stomach upset...the daily taking of Allopurinol has COMPLETELY taken away my foot pain and i have already had small amounts of foods and drinks which i religiously avoided with no gout pain or effects. I can at times get an upset gut but it passes quickly. In my opinion and after suffering chronic gout for years....THIS works. Allopurinol is my saviour! I once took black cherry juice and i caused me much grief and allergy! If you suffer gout....talk to your doctor about a treatment of Predisolon easing you into a daily tablet of Allopurinol at a milligram that suits your system and you will be FREE!! :-) M 43 4 months
100mg 1X day
4/25/2013
Email
 3  gout and IgA nephropathy First two weeks after starting (and first two weeks after increasing dose from 100 to 200 mg) I have had headaches, nausea, diarrhea. Throughout all the time I have taken it, tinnitus and mild dizziness. I hate the dizziness! I have kidney disease and gout. I would not take the allopurinol for just the gout--the side effects are too unpleasant and I would rather deal with 2-3 gout attacks a year than deal with the tinnitus and dizziness. But my kidney doc says the high levels of uric acid are not good for my kidneys, so what to do?? I am sticking with it in the hopes that I will eventually feel better. I am encouraged by the long-time users on this site who have no reported problems. F 61 4 months
12/15/2009
 3  gout i have been taking 300 mg a day along with colchicine. After a few weeks my back, hips, knees, shoulders are sore all the time. i am fatigue all the time. i haven't had an attack in 8 months but hate being sore and tired all the time. M 32 4 months
4/19/2007
 3  Gout Generally nothing too bad. The main thing I've noticed is pins and needles and coldness in my fingers and toes which I have never had before. having read sone reviews here I have noted that my eyesight feels worse (more difficult to focus) and it as clear and my eyes feel heavier. No change in appetite . I suffered with what I thought was a knee or hamstring issue about 3 months in but it cleared up after a week so I feel it just be down to AP. Feel slightly more tired since taking but all the above are minor in comparison to the crippling gout I had. Taken with colchicine initially as I had several gout flares up when taking AP initially as it releases the UA crystals into the blood stream M 43 4 months
100mg 1X day
2/27/2021
Email
 3  High Uric Acid Level After taking this drug for 4 months with no side effects all of a sudden my legs feel like lead weights and my knees are as sore as can be. This onset occurred after taking amoxicillin. I have gotten gout attacks in the past but I had them under control with diet & hydration. Doc still wanted to get my uric acid level down (was 7-8) so I agreed to this Rx. I am having second thoughts now with this sudden on set of side effects. Someone please tell me this will pass - I do not want be a cripple at 50. M 50 4 months
100 MG 1X day
2/27/2017
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