ALLOPURINOL Reviews (ALLOPURINOL)

Average Rating: 3.0 (212 Ratings)

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 ANTIGOUT

 Type: Rx Drug

  

ALLOPURINOL  (ALLOPURINOL):  Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Allopurinol works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.   FDA Approval Date: 1986-10-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ALLOPURINOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ALLOPURINOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Gout Not aware of any been taking fo 40 years eat what I want a few beers a month and no major flare ups . Few lapses in prescription seems high stress can trigger attacks without. No attacks with daily doses M 63 10 years
300 mg
2/7/2012
 5  GOUT I HAVE HAD NO SIDE EFFECTS WHATSOEVER. I HAVE NOT HAD A GOUT ATTACK SINCE I STARTED THIS MEDICATION MY URIC ACID LEVEL WAS 8.8 [ BORDERLINE FOR GOUT ATTACKS ]. IF I ATE "WRONG FOODS- HIGH PURINES", MY URIC ACID LEVEL JUMPED, CAUSING A GOUT ATTACK. MY RHEUMATOLOGIST PRESCRIBED 150MG ALLOPURINOL DAILY, WHICH HAS MAINTAINED MY URIC ACID LEVEL AT 5.0. SINCE I BEGAN, MY FOOD RESTRICTIONS HAVE DISAPPEARED, AND I EAT WHATEVER I WISH. M 80 10 years
4/27/2007
 2  gout i have taken allopurinol for a number of years for gout but have been off it for a while now. The side affects were kidney pain, lethergy and weight gain. I was taken off this because of surgery and not gone back. I eat lots of vegies and take black cherry juice now. No side affects. Cherry juice if good for bursitis as well as gout. You can take pills or liquid. I cured bursitis in less than a week one time. M 55 10 years
1/4/2010
Email
 1  Gout No gout attacks. However this drug had caused fertility issues and decreased sperm count to almost 0. Causes infertility and can also cause testicular failure. Would not recommend to any guy who possibly may want to have children. M 45 10 years
100mg 1X day
7/8/2011
Email
 5  Gout No side effects Great drug for controlling gout. Have tried another which I realised after a while was making me feel down but then changed to allopurinol and have had no side effects at all... or gout attacks. M 35 9 years
1/23/2010
 5  Gout Diarrhoea possibly caused by allupurinol M 45 8 years
300mg 1X day
11/11/2010
 5  Gout None whatsoever. Having had several very painful episodes of gout about 10 years ago, I was put on 300mg of Allupurinol daily. I have not had a single episode of gout since. M 44 8 years
4/27/2009
 3  Kidney Stones Low energy, depression and joint pain. It has reduced my visits to the hospital for Kidney Stones from 4-6/year to 1 every year or two. My low energy has me looking at a correlation with taking the drug. I've asked my GP & Arthritis Specialist but they didn't think so. That said I think they have not done their homework. M 53 8 years
4/29/2007
 2   a) Fatigue b) Strong urine odor c) Mild Depression d) Numbness of toes and fingers e) Right-ankle pain - hard to press gas pedal most of time now f) At higher dosage, extreme arthritis-like pain in neck, back, hands, and joints. My first attack was at 40. It was in my right big toe and a good portion of the lower half of my right foot. It would reoccur twice a year (May and Dec). After reading the page, I listed all of these symptoms because I am or have experienced all of the above in association with either gout, allopurinol, or both. M 48 8 years
4/8/2008
Email
 1  High blood Uric acid SEVERE fatigue, Brain Fog, Joint Pains, All day sleepiness...god knows what else allopurinol did, it’s hard to tell or pay attention to anything when you’re half asleep (zombie) for years while taking it. My dosage was increased slowly and every medicine has drowsiness as a side effect. I’m sure that together both these things made it hard for me to connect side effects to the medicine. Once I had taken it long enough it was like I was a zombie most of the time. I thought I had some kind of cognitive problem I.e. Alzheimer’s, brain tumor etc... I saw all kinds of doctors (gastroenterologists, allergists, neurologists, endocrinologist etc) looking for answers but not one said that maybe it was the allopurinol. My testosterone was low, my vit D levels were low, high blood pressure, high cholesterol etc... After adjusting my diet and stopping the allopurinol (by chance) my pressure went back to normal, I was able to go to the gym and keep going, I feel half alive/awake again. Going to see my doctor soon to see what my Uric acid numbers are, testosterone, cholesterol etc off this medicine. Allopurinol is an adenosine agonist, this effect is probably (maybe not the only thing) why this medicine causes drowsiness, fatigue, brain fog. adenosine makes you sleepy (caffeine blocks adenosine). M 37 8 years
300 1X day
6/4/2018
 4  Gout Fatigue, neuropathy, muscle pain in lower extremities, anxiety, "brain fog" Not sure if allopurinol has any connection to my symptoms M 70 7 years
300 mg
2/25/2016
Email
 3  gout attacks - control uric acid my late husband should have had a diagnosis of kidney disease when he had high blood pressure and reduced his sodium intake along with dietary changes - protein intake. The nephrologist he saw all too late still approved allopurinol(not good - lowers platelets) and prescribed colchcine only for gout pain as needed (side effects too). Better to learn about ways to help the kidney function through dietary management. M 66 7 years
2/20/2009
 5  Gout None. I have been on this medication for approximately 5 yrs. at 300mg. I had extreme pain in my large toe/joint area to the point that any slight movement would create excruciating pain. My regular physician misdiagnosed my symptoms after I told him I thought I had gout and I requested I be tested for the level of uric acid I had in my system. Given I was borderline, he would not prescribe anything and suggested I see a podiatrist, as I may have an issue with my joints. The podiatrist was a real quack in that he shot my joint up with cortisone and get the swelling down, which worked after the second time, but I suffered from this for awhile. The podiatrist even suggested I have the joint of my large toe removed and "fuse" the bones together. I would have none of this and stopped going to the podiatrist. After the last flare up, I went to my doctor and this time demanded he put me on some sort of gout medication. It was not until then, that he prescribed the allupurinol and I have never had another symptom since. Don't suffer through the M 50 5 years
11/28/2008
 5  Gout Slight tendency to diarrhoea. I was informed about this by my doctor. Beats the pain by a mile! Took several months to work fully. Have been completely pain free for sevaral years now M 66 5 years
300 1X day
9/9/2010
 5  Uric acid: high vlues No side effects with 100mg. Some sexual problems with 300mg, athough not very frequent. Normal values of uric acid. M 57 5 years
11/14/2006
 5  Years of severe gout. I have not identified any side effects of Allopurinol. I take two 100mg tabs daily plus two Colchicine which combination I've been taking for about four years and have not had any gout attacks in that time. With this medication I am able to consume any food or drink desired without fear of a gout attack. Prior to beginning this treatment, I had suffered years of severe pain and periodic severe gout attacks which I countered with Ibuprofin. Kidney damage caused by the Ibuprofin dosage has reversed since stopping all NSAID usage. M 69 5 years
8/3/2006
Email
 4  Gout None of the classic side effects As I passed into my 50s (I'm now 69) attacks of gout in either my knee or ankle would turn me from a reasonably energetic person into a hobbling old man. Allopurinol stopped that within two weeks. M 69 5 years
100mg 1X day
6/17/2021
 5  Gout None After the initial 'pain' for around 2 months, have had no problems since M 51 4 years
100mg 1X day
4/8/2011
Email
 5  Gout None Very effective at controlling gout. I have had no negative side effects. M 57 4 years
9/25/2009
 5  Gout When I first started on Allopurinol, it triggered an acute attack of gout (my worst ever) but since then my symptoms have stadily gotten better to where I haven't had even a twinge in the last year or so. I initially resisted taking Allopurinol and tried to control my gout with diet, but after several attacks over a couple of years, I realized I was damaging my joints and the pain was causing me to not exercise. I regret not starting on it eariler. M 54 4 years
8/13/2007

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