DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  both knees Osteoarthriis Total relief from shot in each knee. No side effects. I have osteoarthritis and bone spurs in both knees with severe chronic pain and inability to walk or bike without legs locking and severe pain. A shot of Depo-Medrol in each knee lets me go back to free walking (without a cane) and bicycling without 99% of the pain. F 64 15 years
40 1X AN
3/24/2017
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 4  knee pain I have notice an increase of broncitis. I do not know if this is the reason, but I have loss muscle mass in my legs. But, I continue to get the shots because it helps the pain in my knees plus the pain in my back and legs. I have been getting these shots for about 3 years now. F 64 3 years
1/29/2008
Email
 1  spasm in neck and thoracic spine The injections caused a flare of SEVERE nerve pain and spasm in my neck and upper body that lasted almost a month, accompanied by the following side effects: flushing and burning on my face, a rash over my upper body, coated tongue, severe thirst, and heart palpitations. The spasm for which the shots ostensibly were given is worse now than it was before I had them. I am extremely angry about this, because the doctor didn't even inform me that he was going to do the shots that day, or that he planned to inject a steroid. I already knew that steroid injections are dangerous. I am worried that these injections might have caused other effects than those I'm aware of. I just hope this will stop. I will never see that doctor again. If I thought it would make any difference, I would report him to his medical board. He also prescribed more of this wretched drug, as well as an anti-seizure medication AND Prednisone. Steroids anyone? I have come to hate pain doctors. They know very well the effects these drugs have on people, and they continue anyway. F 64 1 days
1/24/2010
 5  RA & Osteoarthritis Solu-Medrol have relieved my pain and swelling now for years I look forward to for my monthly shot of relief. Though it has caused me to gain weight. It is my wonder drug. After your system get use to it side effect vanishes. F 63 4 years
100 mg
1/17/2016
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 4  Low back and sacrum pain injections This was a one time injection given by my pain doctor in his office. After two weeks I got a terrible itching rash that spread from my arms to my stomach, legs, back, neck, and buttocks. It has been going on for 4 weeks. Went to a dermatologist who put me on prednisone to relieve these symptoms. Still have them and my course of prednisone will end in 3 days. I cannot sleep at night because of the itching. The rash is horrible! I have had a terrible allergic reaction to this steroid. There are many different types of steroids that doctors use for pain relief and I will never use depo medrol again in my life. This is agony! F 61 1 days
1cc
3/2/2016
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 2   Received Shhot at noon and at 6:00pm, the pain was worse that before I got the shot. Five days out, I am still in pain and cannot lift my arm over my head and put arm behind my back. Doctor told me nothing of the drug -- just that it was a steroid. F 61
80 MG 1X day
9/7/2010
 1  Hip injection for pain After the injection in my left hip. It got worst. I cannot raise my leg. Hurts terribly to walk.cannot stand on it long. Bend I have limit mobility. This medicine needs to be taken off the market. F 60 1 days
12/22/2016
 1  SI-Joint Injection Heart Palpatation, tremors, feeling of low sugar, disconnected, short term memory; plus, only received 4 days relief. Had injection on 3/27/18; going on 8/weeks,, still having side effects. Would never had agreed to this injection had I known about size effects. Doctor, who injected, disclaimed any connection between DEPO-Medrol and side effects. Had to do my own research to find connection .Reported this adverse reaction to FDA. F 60
80 MG 1X day
5/24/2018
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 5  PMR Seronegative RA None at all. I have taken oral steroids & had the most awful side effects, so came off on a fast taper. Since having this steroid injection 7 weeks ago I feel normal again. No joint pain, sleeping properly. I've even managed to lose 19lbs since I had it. F 59 1 days
120MG
11/30/2015
 3  Osterarthritis Knees Used for approx 1-1/2 years with no side effects. After having a stroke Jan. 2009, had another injection about 8 months after the stroke. Side effects were elevated blood presure and rapid heart beat. Depo-Medrol worked for the first 1-1/2 years, but after my stroke, I think that my overall "good" health outweights the side effects of this medicine. (blood presure and rapid heart beat) M 59
40 mg 4X AN
2/4/2010
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 1  Severe burning due to buldged discs First, my blood pressure shot through the roof, that lasted about a week. And on top of that i had terrible headaches and sleeplessness. In a week i slept at the most 8 hours. Now i am constipated and my pain and burning still persists. I would not recommend this drug. I don't know how it works in pill form since it was injected in my epidural space. F 59
2/27/2007
Email
 5  knee pain This is a one time injection to the knee. Injection is painful, but the results are wonderful. The relief may last for several months possibly a year. F 58
1X day
8/1/2010
 1  Rotator cuff The shot relieved the pain in my shoulder but my blood pressure has soared, almost doubled, and my pulse randomly races to 100 or slows to 50. This is accompanied by a feeling of lightheadedness, fogginess and odd skin sensations ranging from itch to prickly sweat. It has now been two weeks and these side effects are showing no sign if diminishing. I would prefer to have shoulder pain. This is scaring the crap out of me. I've long been healthy with low BP. Don't do it. F 58 1 days
60 1X day
11/30/2016
 2  I had fractured collar bone . My arm can not move up and sore. Before taking this medicine my arm can move half way now it's difficult and so painful.thanks Not help for muscle pain. F 57 0 days
12/19/2017
 1  Frozen shoulder I received one Depo shot for frozen shoulder in Nov 2016. Approx 1 week after that I experienced heart rate up to 140, anxiety, panic attacks, 10 lb weight loss, depression and insomnia. Went to my GP who said it was not from shot, blood work was normal, she prescribed ativan, which I did not take. Starting seeing a Naturalpathic who said my adrenal function is low, even though blood work is within normal(but on low side) and symptoms probably due to shot. I am now on mega B, C and stress vitamins and take skullcap for anxiety. I am 4 months out and the lingering side effects are anxiety/depression and occas panic attacks, which my naturalpathic and I are working on. I have never had any of these before and they are quite debilitating. I feel better overall but by no means 100%. I exercise and eat healthy and all of these things help I think. Alcohol and caffeine makes symptoms worse.I am just waiting out these lingering symptoms and hope they subside in time. 57 1 days
not sure 1X O
3/15/2017
 1  Inflamed ankle. Intra articular injection Pain increasing since the injection. Now 9 hrs ago and I have never felt such pain and still going up. Impossible to move any part of my foot, toes etc. Immediate pain beyond imaginable. Never take this EVER. NO MATTER FOR WHAT. CAN ANYONE GIVE INFO HOW THIS PAIN LASTS OR WHAT CAN BE DONE. M 57 1 times
40 mg
3/13/2020
Email
 1  BronchoSpasm (Asthma) I've had depo before and it never did this to me before. Extremely rapid heart beat, irregular heart beats, and fluttering heart with any movement (no endurance). Shallow breathing. Could not walk far without feeling my heart was about to burst. Could not swat a fly without my heart overreacting and going wild. Slightest emotion caused my heart to go wild. Felt like acid or fire running through my arm and neck veins. Twice I almost died. Felt like I was in the 7th circle of hell! Felt like fire, then antifreeze, running through every cell of my body with rapid heart. Muscle weakness. It has been 20 days since receiving the shot and I'm still having symptoms. Have not been able to walk through a department store without feeling like my heart can't handle it. Going to have a heart ultrasound to ensure depomedrol didn't blow my valves. Having been praying like crazy to get well. This stuff is poison! Never again!!! (He should have just given me steroids by mouth.) The labs making this stuff need to be inspected and cleaned up! F 57 1 days
80 mg 1X day
8/21/2014
Email
 4  Fibro, RA, OA, stenosis & sciatica Don't heal as quickly. Reduced sinus swelling, allergies better. Happened to Get shot in hip w/bursa swelling (20+yrs)- better, pain in lower back - better, pain from Fibro - less & less flares, arth pain - better & better life because of less pain, better motion & emotion! I live the life - 40yrs Fibro & back/hip pain many of u describe as side effect. I'm sorry that maybe dosage wrong or whatever reason it was a bad experience for u. I am so grateful my Dr cared enough to find something that helped me. I have to wait 30 more days, he says not good to take more than 3x's a yr, & I am counting down the days! F 56 6 months
20
9/2/2014
 4  Impingement Syndrome of Right Shoul My shoulder is okay. Some residual pain at different times of the day. Had shot on Wednesday and was fine Wednesday and Thursday. Friday woke up with Flu-Like symptoms. Bones hurt and have chills. Wearing flannel pajamas in August. Some rash on upper body. Never had Depo-Medrol Injection. Always Kenalog. Feeling like Crap. In bed all day Friday. A mac truck must of hit me in my sleep. F 56 0 days
Injection
8/4/2017
 4  BURSITIS bEST RESULTS ABOUT 5 DAYS AFTER INJECTION F 56
9/20/2005

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