Average Rating: 3.4 (15 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MYSOLINE: Reviews Summary  |  Drug Safety Information

 5  Brain tumor removal caused tremors Tired at first,but not a problem after approx 2 weeks. I draw blood at work. This has helped better than any other med. F 46 7 years
30 mg 2X D
 1  epilepsy extreme suicidal depression, lack of apetite, very bad sleepiness almost lost my life to this stuff; drs. did not tell me it was related to phenobarbitol which I got too depressed to take. Recovered my mood once I was off it. F 51 12 years
do not rem 2X D
 5  Epilepsy I was originally prescribed phenobarbital as a 12 year old, but it made me too sleepy. Dr. switched me to mysoline at 13 which has had no side effects to mention. I have lived virtually seizure free most of my life except when off my medication. I have had only one seizure in 13 years and that was the result of a new neurologist taking me off mysoline in 1997. I had a seizure after 4 days without medication. I had gone seizure free for 11 years prior to that. I have been able to live a full life and accomplish my goals due to this medication. I took the name brand until it got too expensive and have been on generic for the last 5 years M 55 42 years
250 3X D
 4   familial (essential) hand tremor started with 25mg daily for couple of days, then morning and bedtime, then 50mg daily etc, then titrated up to 250 am and bedtime. Face feels flushed, headache a lot but tremor is lessened. Don't know if I want to increase it more or not at this point. Will discuss with neurologist. I doubt there will be any added benefit by increasing dosage vs side effects. For those still searching suggest for detailed info. M 73 3 months
 2  essential tremer drowsiness, confusion, unsteadiness, losing words, so slowed down mentally I feel stupid and can't function I am taking 200 mg a day and it hasn't helped my tremor at all. I can't take inderal because my blood pressure is already too low. I'm trying to give it a chance, but I can't live like this much longer. F 48 1 months
 5  Essential Tremors Maybe some tiredness but cannot differentiate from Tenormin and other drugs M 80 16 years
 3  essential tremors sleepy took it for awhile,stopped, tremors seemed worse,taking it again but see no effect except sleepy 50 mg daily M 64
 5  epilepsy none After my diagnosis in 1999, I spent years trying different drugs that had side effects I couldn't tolerate. This drug has worked perfectly for me. Ironically, my Dad, who is a GP, tells me that Mysoline is a step away from the phenobarbitol I was given for a time as a young child. F 45 6 years
 5  Epilepsy some headaches I have been taking this medication to control myoclonic seizures, I take a small dose and it works very well in controlling them. I got pregnant a year after taking it and continued to take it throughout the pregnancy. The doctor thought the worst thing that would happen to the baby would be a cleft palate or lip. I had preterm labor with my first baby, but not as bad as with my second. Not sure if the medication caused this or it I would have had it anyway. But I do have 2 very healthy babies, without any side effects from the meds. I was also able to nurse both of them for a least a year each. F 27 5 years
 3  essential tremor dulled down, extreme exhaustion about 5 hours after taking it, intensifies the effect of alcohol I am a reasearcher and take mysoline to do laboratory work. I took inderal first, but I have asthma and it ended up exacerbating my asthma. Anyway, mysoline does help a little, I found I take 12.5 mg (1/4 of a pill) 2 hours before what I am doing and it helps - but I need be done before five hours or I become stupid and screw up my experiments. I once took it once a week for an ongoing experiment for 12 or so weeks and I do think by the end the side effects improved. I really wish I could just take inderal. That is a great drug for the shakes. Note, I take this drug as needed. F 27 4 years
 3  essential tremor drowsiness, lack of energy very effective in reducing the tremor M 55 2 months
 1  essential tremor double vision, slows brain function, it's a downer M 78
 4  essential tremors Some iritability. Helped a great deal with my tremors. F 55
 4  essential tremors Some iritability. Helped a great deal with my tremors. F 55 4 years
 1  hand tremors Walking around in a fog / very tired even though took before bed did not seem to help my tremors after taking for 6 weeks. I felt that I was too out of it to function. M 40 6 weeks

MYSOLINE  (PRIMIDONE):  This medication is used alone or with other medications to control seizures. Controlling and reducing seizures lets you do more of your normal daily activities, reduces your risk of harm when you lose consciousness, and lessens your risk for a possibly life-threatening condition of frequent, repeated seizures. Primidone belongs to a class of drugs known as barbiturate anticonvulsants. It works by controlling the abnormal electrical activity in the brain that occurs during a seizure.   (Sources: U.S. Centers for Medicare Services, FDA)