TOFRANIL Reviews

Average Rating: 3.0 (19 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on TOFRANIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TOFRANILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety,insomnia,depression weight gain, memory loss Helped tremendously with panic attacks and anxiety. Only drug that has worked and I tried everything in every class of drugs. Helped me get off alcohol. I have some memory loss but in the long run the very positive affects outweighed the negative. Gained weight because food suddenly tasted good again. It was worth every pound but I can deal with that by staying off the sugar and carbs. Helped also with severe insomnia by taking tofranil pm 150 mg/ F 60 6 days
200mg 2X D
9/24/2018
 4  Depression Dry Mouth, elevated pulse, fatigue at first, sexual side effects. This was a pretty good antidepressant for me. Only persistent side effect was extreme dry mouth. I had to quit because my tonsils started swelling and I had other mouth problems. Actually improved my cognitive impairment, and started working very quickly. Got up to 75mg in less than a week and stayed at that dosage until I had to quit. Bear in mind this drug is metabolised to Desipramine, a very strong NRI. It will take 2-3 weeks to clear your system. M 33 5 weeks
75mg 1X D
1/25/2016
 4  Depression, anxiety, panic attacks Dry mouth..some weight gain.. I've been on imipramine (generic for tofranil) for over 22 years.. Works better than other older meds! I also have OCD and panic attacks.. It has not helped much with OCD and I'm now trying to find a drug that will let me take lower doses of tofranil and add Luvox to the mix..for OCD... IM ON A HIGH DOSE....200 mg just be sure to have your blood panel every year to monitor the kidneys and liver! I'm an extreme case of depression and am afraid to take anything new for fear of it killing me or making me have high anxiety.. Tofranil doesn't take all the anxiety and that's why I was on klonopin! But now, no other meds are used! I am afraid to try something new, this has helped me to feel "real" for years!! Trust it, I did!!!! F 59 10 years
200
1/5/2016
 1  Depression Panic Disorder Made me feel more depressed after a few days use. This is the very first antidepressant I tried in 1986. Actually intensified my depression. I felt very sullen and hopeless. M 50 30 days
25m MG> 3X D
9/30/2014
 2  panic attacks periods of severe insomnia, agitation, anxiety, obsessing on trivial things, urinary retention I took this 18 years ago for a month or two for panic attacks and tapered off with no problems. Last winter a series of panic attacks occurred for the 1st time since '96.. so I asked the Dr. to prescribe these. After about 3 months, serious insomnia, anxiety kicked in. Finally tapered off this drug and back to normal. Works to stop panic, but not a long term solution for me. M 55 6 months
50 1X D
9/13/2014
 5  Depression, panic disorder Dry mouth, occasional constipation, lowered blood pressure, slightly elevated pulse. This drug, along with therapy, saved my life. The side effects (for me) are minor compared to the vast benefits--an end to panic attacks and depression. F 53 24 years
75-150 mg 1X D
3/19/2013
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 1  TR Depression Mouth dryer than a desert, serious urinary retention I'm talking standing in front of a toilet for 15-20 minutes and giving up. This med would have Christopher Hitchens and Richard Dawkins on their knees begging god for pee. Awful M 31 24 days
150 1X D
1/25/2013
Email
 1  depression psychosis, tiredness I forgot the dosage, its been awhile but immediatIy i was hearing strange noises, I was convinced there was a ghost in my house. Doors opening, music playing, footsteps. It started the day I started taking it, when I told my doc he got me off immediately and switched to lithium which has been a blessing F 27 14 days
60 1X D
6/6/2011
Email
 4  panic/generalized anxiety This stopped some serious panic attacks dead in their tracks. For that I am grateful. I tapered off them due to my aversion to drug therapy, but would definitely take these again if needed. M 37 45 days
5/28/2008
 1  depression/bipolar II i was already depressed before taking this but it did keep me from doing and self mutilation. in fact i couldnt do anything. I couldnt talk to anyone without crying, i had terrible headaches, barely moved at all, never left the house and couldnt sleep... basically cried all day long the entire duration of time that i was on this drug and could not do anything else. horrible-killed my social life F 19 2 months
2/25/2008
 2  anxiety, depression, insomnia 125 mg at night: dry mouth, mild weight gain (8 lbs), dizziness on standing, cravings for sweets, headaches, very tough to stop taking this med. I switched to this med for 5 years because it was only one of 2 antidepressants offered at my college health center. Previously, I took desipramine for 1 month, which was much more effective. Because I did not know much about antidepressants meds back then, I was not aware of just how great the difference was between these two meds. Tofranil helped me sleep somewhat. It also helped me concentrate and focus, and it reduced my anxiety, but not by much. My sex drive was fine, I had NO sexual side effects at all, nor did I have any memory loss that I was aware of. I have tried 3 tricylics and had no sexual side effects on any of them - so take note that not everyone has that side effect! BUT, after 2 years of taking tofr., it activated restless legs syndrome, which continued until I stopped the med. I also got headaches. Stopping it was extremely difficult, I had flu like symptoms and went through a very tough withdrawal. This drove me nuts, as I felt like i could not stop these meds. F 27 5 years
4/1/2007
 3  vvs tired all the time, moodiness, inability to focus correctly on tasks (including driving), weight loss withdrawl was hard..don't up dosage to fast. Make sure to take at same time each day..if you don't you might start to get jittery. It helped a bit with pain and at least let me sleep. I was so tired all the time and just well..stoned..that the small amount of pain relief I got wasn't worth it. F 29 6 days
1/13/2006
 3  vvs tired all the time, moodiness, inability to focus correctly on tasks (including driving), weight loss withdrawl was hard..don't up dosage to fast. Make sure to take at same time each day..if you don't you might start to get jittery. It helped a bit with pain and at least let me sleep. I was so tired all the time and just well..stoned..that the small amount of pain relief I got wasn't worth it. F 29 6 months
1/13/2006
 3  anxiety I had insomnia at the beginning and then memory problems started. I read up on some studies linking imipramine to decreased memory and I am a med student and can't lose any memory which I really need. So now I am trying to come off the drug, but experiencing insomnia again. Has anyone else noticed the decrease in memory? F 23 30 days
9/1/2005
 3  psychotic depression, panic, ocd rapid weight gain which leveled off after 6 mths. I gained 30lbs. This drug has a soothing quality to it that I find wonderful. I am on a high dose at 150mg. Also helps to calm down, relax and sleep. F 26 14 months
8/2/2005
 5  ADD slight spacey feeling first day of taking it. mild dry mouth occasionally in first six months. increased tolerance to alcohol. originally taking 25mg once/day in morning, would feel tired pretty early in the evening. switched dose to bedtime, no longer felt drowsy in the evenings. has been great treatment for ADD. conductor to the orchestra, if you will. have stopped a few times when rx refills ran out, and definately noticed a difference. M 28 8 years
5/1/2005
 5  generalized anxiety/panic attacks When on high dosage, had some lightheadedness upon standing up quick and some dry mouth. it allowed me to be functional again and then lowered dosage considerably (to 10 mg) - still need that dosage to keep from jumpiness, generalized anxiety. when on low dosage, no visible side effects. Worked great on panic/anxiety F 36
12/22/2004
 4  nerve pain a littel dry mouth, vivid dreams in dose > 10 mg, swollen glands (throat) this small once a day dose of 10 mg (about 1/8th to 1/15th of the dose for depression) is a helpful part of a F 50 3 years
12/9/2003
 2  panic attacks M 8 years
10/4/2002
  

TOFRANIL  (IMIPRAMINE HYDROCHLORIDE):  This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.   (Sources: U.S. Centers for Medicare Services, FDA)

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