Reviews for METHOTREXATE SODIUM

256 ratings: (taken because of RA arthritis)

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 ANTIMETABOLITES

 Type: Rx Drug

  

METHOTREXATE SODIUM  (METHOTREXATE SODIUM):  Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on METHOTREXATE SODIUM: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR METHOTREXATE SOCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Ra Bloated stomache, no other side effects, could work better for the ra still have swelling F 38 1 years
20Mg 1X W
5/23/2021
 3  Lupus/RA Extreme nausea, vomiting, and flu like symptoms take at least 3 days to subside after taking my dose. Vomiting seems to occur if eating or drinking on an empty stomach the day after taking a dose. This medication is so hard to take for me. I eventually stopped taking the medicine every week because I could not function regularly. I now take it every other week and it seems to help, but the symptoms never stopped or decreased. It helps with the muscle spasms and pain, joint pain, but seems to help me most with my butterfly rash on my face. It is the only medicine in 3 years that has had any positive effect and my rash is almost completely "gone" and stays away. This medication is really tough to deal with, but personally I believe the results are worth it if you work with your doctor to find the right dose. F 22 1 years
6 mg 1X W
12/2/2020
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 1  Hyperkeratotic eczema Severe fatigue, severe bloating with stomach pain, some nausea, deep depression, cry for no reason. Feel terrible 5-6 days out of 7 F 48 4 weeks
7.5 1X W
10/20/2020
 3  For possible Rheumatoid Arthritis Feeling like l have the flu for a couple of days after taking it. Jut not sure it is working to it's full capacity, because l still have a lot of pain. 61 3 months
16 milligr 1X W
9/28/2020
 4  RA Made me very tired and depressed. Also had palpitations with it. It helped with the pain but it was hard for me to function while taking it. M 36 3 months
50mg 1X W
6/10/2017
 5  RA I started on 3 pills a day then slowly up to 7. I had had gastric bypass in 2009 so my stomach was not dealing with the meds well. Plus I think the MTX was not getting absorbed enough. Was switched 3 months ago to injections. WHAT A DIFFERENCE! I am starting to feel alive again. I'm lucky enough to work at home so I take mine on Tuesday and that night and all day Weds. I am pretty out of it. But no flares or pain anymore. Fatigue more than anything. I was diagnosed ADHD 3 months prior which to me was a blessing because it helps the brain fog and fatigue during the day. It still takes a couple of hours after getting out of bed to feel my best but that's better than pain 24/7. I learned something VERY IMPORTANT about the day you take your pills/injection from a woman on a support group that worked for me. Drink a lot of water and eat. Snack on healthy things all day. And avoid having to do any extracurricular activity Don't push yourself. I learned that twice so far by scheduling doctor appointments and errands same day and paid for it dearly. I'm an avid horse woman and I ride a lot now. This time last year I was a mess and in such pain I couldn't ride, barely walk and cried a lot from pain. I can use my hands now and am enjoying life. F 51 7 months
1 ML 1X W
6/15/2016
 1  Rhumetiod arthritis Shortness of breath headache foggy rapped heartbeat stomach ache Suicidal Thoughts It is a very scary drug F 57 3 months
17.5
3/9/2016
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 2  RA bloating, angry stomach, dry skin and sometimes I don't get my period for 3 months. Or sometimes it doesnt stop for 2 months. F 36 1 years
3/3/2016
 3  to control granuloma stiffness and Terrible back pain upper back joints tiredness pressure on body muscle problem leg spasm and pain I duno F 40 2 months
now 20mg
5/11/2015
 2  Rheumatoid arthritis Brain fog, stomach pain, throwing up, problems with blood sugar, headache. I would basically be out for 2 days after taking this drug. Ruined my weekend since I couldn't take it during my school days Barely did anything for the pain or swelling. I have since stopped and switched to enbrel which helps a ton more F 18 2 months
40mg 1X W
9/24/2014
 1  Psoriatic arthritis Brain fog. Increased incidence of flare ups. SLEEP - I could sleep anywhere at any time. Lack of concentration. No decrease in pain. And it didn't stop the damage to my joints though it was described to me as a disease modifier. Blood work got worse month after month and still the insisted I take it. They don't call this bottled death for nothing. My pain never eased up. The inflammation didn't go down. The flare ups were frequent. I couldn't think straight - which is why I stayed on it for 5 years. I threw it all in the bin over 3 years ago and I've never looked back. Less flares, less pain and my blood tests returned to normal after years of actually getting worse. My head cleared and I don't sleep all the time now. I eat anti-inflammatory foods and I can keep the symptoms at bay. As a disease modifier Mtx sucks - an MRI still showed progressive damage while on the drug. This drug does not work for psoriatic arthritis - don't let them tell you it does. There is an article on the net by the Rheumatological society that states that this drug does not work for PsA. My rheumatologist and doctor can't seem to hear me say "IT MADE ME WORSE". I wouldn't touch this drug again ever. or any other come to think of it. I don't take anything for PsA now, just the right foods and I have been so much better since throwing this poison in the bin. They aren't "health professionals" anymore, there is no "Health care" - they're just drug dealers in my opinion and if you can treat yourself you should. Nutrition is the answer for controlling your inflammation. F 50 5 years
25mg 1X W
7/10/2014
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 2  Severe rheumatoid arthritis Nausea. Upset stomach. Constipation. Headache. Brain fog. Hair loss...! This is my second time trying MTX, my rheumy is hoping this time will be the magic trick. Last time, I took 8 pills a week. I've always had thick hair... and it definitely started thining a few weeks after. I have nothing to really praise... hasn't done a miracle job yet. But hey. Who knows. F 20 2 years
2.5mg, 4 p
5/25/2014
 2  RA nausea, vomiting, headache, peeling flaking skin on face around eyes, greatly increase eye irritation, eye infection, constipation, dizziness and vertigo, fatigue The headaches and GI distress were so great that I had to stop taking one of my other meds. The combination caused too much nausea, stomach pain, and vomiting. I also sometimes have to stop my NSAID because the MTX along with it is more than my stomach can bare. So far it had not touched the pain. The doctor put me back on prednisone which helps but they don't recommend you take that all the time. I had to miss work last Fri because of vomiting and feeling really bad. Didn't want to move all weekend and then had vertigo on Mon so I miss work again. Now I have to take medicine to help the vertigo too. Today is Thursday and I still have some vertigo but it is mild now. I plan to ask the doctor to start Enbrel next trip F 50 2 months
17.5 1X W
11/14/2013
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 2  psoriatic arthritis I feel sick all the time ,constant sore throat,memory loss and confusion I feel tired bad tempered ,I feel chesty and weezey in the morning my period is all over the place and a small amount of weight loss and to top it I keep getting Candida F 41 2 months
17.5mg
5/12/2013
 2  RA/UVEITIS IRRITABLE, TIRED, FOGGY, HEADACHES (MOST DAYS) I WAS DX WITH RA WHEN I WAS 17 YRS OLD BUT HAVE MANAGEABLE JOINT SYMPTOMS. I TAKE MDX FOR UVEITIS (RA IN YOUR EYE) AND HAVE NOT SEEN IMPROVEMENT WITH MDX USE, EVEN WITH A STEADY INCREASE IN DOSAGE. EVEN WITH 20MG I HAVE RECENTLY HAD THE WORSE FLARE UP IN YEARS. I AM CURRENTLY LOOKING FOR ALTERNATIVE NATURAL REMEDIES THAT DON'T HURT ME TO HEAL ME F 27 18 months
20 1X W
8/25/2012
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 5  Rheumatoid Arthritis Terrible, terrible nausea for 2 days after dose, diarrhoea, tiredness BUT cures my arthritis and allows me to live an active life free from pain. Side effects mean I struggle to keep taking MTX consistently, when I do my arthritis is cured. F 23 11 years
20mg 1X W
6/8/2012
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 5  RA very slight nausea the first few doses, but none after that. I think MTX gets a bad rap. Never had a problem with this drug; been taking it since 2007. Along with Enbrel injections and folic acid to reduce (in my case, eliminate) any side effects, my RA is effectively controlled. F 49
1X W
3/18/2012
 3  RA I take my 4 pills (10 mg in total) on Monday. For the next 48 hours after, I feel exhausted, head feels heavy and I feel really bloated. I have been having trouble sleeping and been very moody also. The symptoms for my RA have drastically improved but I just feel crappy for 3 days out of 7. Now I have to increase to 15 mg. starting my next dose. I hope it doesn't worsen the side effects. F 40 30 days
10 1X M
2/29/2012
 4  JRA Tiredness, mood changes, foggy state of mind F 16 3 months
25
1/23/2012
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 5  Seronegetive RA loose stools at times For about 1 month my ankles and joints hurt so bad I couldn't wear heels and it hurt to walk. I went to the rheumatologist and he started me on methotrexate 10mg/week and prednisone 10mg/day. I ended up getting off the prednisone after a year and instantly after I started the meds my joints felt great and I was able to be active again. Last year I was in numerous races, bike rides & ski events all because of the methotrexate. I'm very thankful for the increased knowledge the medical world has about RA. Hope someday they will find the true reason behind this disease. F 23 1.5 years
10mg 1X W
1/18/2012
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METHOTREXATE SODIUM  (METHOTREXATE SODIUM):  Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.    (Sources: U.S. Centers for Medicare Services, FDA)

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