Average Rating: 2.5 (89 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on BUPROPION HCL: Reviews Summary  |  Drug Safety Information

 3  Depression, Anxiety Sweet and salty cravings, gaining weight, sex drive non existent, heart palpitations at first. Took 150 XL before, this isn't any better, irritable, feel like a zombie, no motivation. On the 150XL felt clearer headed, had to stop due to heart palpitations. F 58 2 weeks
75 mg 1X D
 1  Depression and anxiety Muscle pain, joint pain, excessive sweating Side effects started after one year of taking. Had upper back pain, neck pain, and knee pain. Forgot med on vacation. All these aches and pains and excessive sweating went away. Did help w depression at first, then didn't help anymore, probably because all the side effects were causing depression. Didn't even realize it was this med causing these side effects. So glad I Forgot this med on vacation. F 38 2 years
300 1X D
 2  Depression, anxiety It's difficult to pinpoint which med causes which side effects, since I take 5. But what I can say is that I feel no improvement in my mental health. F 20 3 years
300 MG 1X D
 2  Depression, anxiety Initial hyperactivity; lasting tinnitus. The first few days taking 150mg bupropion I was wired--I only got about 15% of any given task done, but I did 15% of a whole lot of tasks. Once that settled out it didn't do much for me, so my doctor bumped the dose up to 300mg, which did help my mood a little but also gave me tinnitus. The tinnitus is still present a year and a half later; apparently sometimes it's permanent and sometimes it's not. (It's mild enough that I only really notice at night, so it's manageable, but it's annoying.) F 25 7 months
150-300mg 1X D
 2  For depression and anxiety Feeling thirsty shaky zoning out a lot M 43 7 days
75 1X D
 1  Smoking cessation Trying to quit smoking. Didn't really help and increased my anxiety. Also was on Paxil previously and gained a lot of weight. Was hoping that Bupropion would decrease my appetite but no such luck. Do not recommend if you already have anxiety issues. F 44 7 days
150 1X D
 5  To stop smoking, then for anxiety Smoking cessation was successful with little desire to begin smoking again. No bad side effects that I am aware of. I do feel calmer and take situations in stride as compared to wanting to "fix" everything that occurs. My anxiety is GREATLY reduced allowing me to accept the things that I can not "fix" nor change. F 71 14 years
150 mg 2X D
 3  Depression and falling asleep I am feeling spaced out and dizzy My doctor had me start off with 75 mg a day for 5 days then I started to take 150 mg a day 75 in the morning and 75 in the evening . I took that for 2 days then on the second night I woke up feeling like I was going to have a seizure. I have had seizures before so I know what it feels like . I was able to calm my self down and the feeling eventually went away. I called my doctor the next morning and he put me back on 75 mg until I see him in 4 weeks . F 43 21 days
 2  Depression, anxiety Angry all the time. Have become abusive. Crave sweets big time! F 65 3 days
150 1X D
 5  Depression and bipolar I was so nauseous all the time but I knew the pill was helping me. I started taking 2000 mg ginger root pills on a empty stomach every morning and waited a hour before I started moving around, not been sick sense I taking ginger root. I advise you to try the ginger root before giving up on the medication. I was so sick during the day I could not work my job. Thank God for ginger root. F 53 3 months
 4  Bipolar 1 Tinnitus- really severe. Always have had it since childhood, but it was something I rarely noticed. I take other meds as needed, but now I think itís the Bupropion. I also remember being more focused and alert when my dosage increased. I can totally endorse this medication as being moderately effective for depression. I can also see how it is used as a smoking cessation drug, because even though I still smoke occasionally, it is not as enjoyable and I usually only smoke socially now. It kind of ruins your love affair with cigarettes. I can honestly say I canít stop taking this drug - I tried going off and thank God I have a very reserved psychiatrist who supported that decision, but Iíll be damned if I didnít suffer profound depression and had to go back on. Classic chicken or the egg. But I didnít get any of the weird withdrawals that SSRI or SNRIs cause. F 50 20 years
300mg 1X D
 1  Depression Breathing is very difficult and the Buproprion brings on a terrible asthma attack! When I was on the Wellbutrin, I was fine for a year or longer. I started on Buproprion about a month ago... It's totally different and causes me to have terrible side effects! This is really deadly to me and I will never EVER take this horrible med again!!!!! Can't believe the difference in the two drugs. It's like a totally different drug that was prescribed for me. This could cost someone their life and May have. Too dangerous...It should not be on the market to sale!!! F 65 0 months
 1  depression HORRIBLE metal taste, sore teeth, naseau, no interest in food,pre-existing TINNITUS volume ramped up x6..wanted to run screaming away-no where to run to...anger, taste like poison, bad breath, film in mouth, feeling worthless and flat.very tired. F 63 25 days
1/2 of 75m 1X D
 4  Depression and anxiety Dr just bumped me up to 450 from 300. I am experiencing a metallic taste, and extreme thrist. More importantly, this drug has saved my life. There's dark days, but I manageing them better Will continue taking it Out of the drugs I have been taking, this is the most benign side effects F 62 4 months
 2  Depression Heavy headed feeling, fatigue, blank minded, an overall grey feeling, loss of appetite. Feeling of not caring about anything. F 29 4 days
100 2X D
 3  Major Depressive Disorder, PTSD So far it's only been a couple of days so this is just a preliminary review of my symptoms coming on to the drug. Feeling nauseous (like motion sickness), malaise, body aches, head feels stuffy, spaced out at times, energetic at others. I am hyper-aware of my symptoms due to my knowledge of medicine so please read this only as a beginning review. I intend to take this for 6 months at least before making a decision unless it affects me in such a way i have to stop. Taking the extended release tablet once daily in the morning. So far, I've actually slept better than ever but this may be due to my zero exercise before taking this and comparing it to the exercise I have the energy to do now tiring me out. Keen to see where this goes. On 40mg Fluoxetine also. F 20 3 days
 1  Depression No sleep, agitation, verbally abusive, manic, short-tempered. Increased sex drive and performance. Had to discontinue due continuing side effects. Did help with calming my mind a bite at 150mg. M 57 4 weeks
150mg to 3
 2  ADHD secondary depression Unusually more vocally angry that before... little things that didn't get to me too much now do. I have really vivid dreams. No nausea, no headaches, no weight loss or gain. Thirsty a lot, sex drive is still up-in-the-air on that one. I use to have a very Racy mind... my mind was always thinking of anything and everything I was intersted in learning and filling my mind although most of the time it was frivolous info. I had really good situational awareness... not now. my mind slowed down but now I just don't really feel right. No longer interested in things I use to do. I feel like I'm being blocked mentally. Weird feeling that I am not thinking or doing things. I can sit in a chair and lot at the wall and my mind will be blank... no ideas likes before no thoufhts or who when where how why. I feel dead I use my head. I'm really lethargic to point of just not wanting to do anything... some days I'm manic and can't wait to take care of things. Now now now or I feel like I wasted the day. I don't like the way my mind works now. I want a real ADHD med not an off-listed that may help. M 51 2 weeks
 3  Depression Constipation; Slight "Drowsiness"; Inconsistence sleeping patern This was a replacement of another anti depression drug M 46 2 weeks
150 1X D
 4  Depression I was mistakenly taking 1 tablet a day which only made me have hallucinations and vivid dreams. After I increased to the prescribed dosage of 2 a day, I felt a lot better, no longer agitated so easily or feeling like staying in bed all day. But the higher dosage caused a rash, dry mouth and cravings for junk food. F 58 1 years
100 mg 2X D

BUPROPION HCL  (BUPROPION HYDROCHLORIDE):  Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.   (Sources: U.S. Centers for Medicare Services, FDA)