TRAZODONE HCL Reviews (TRAZODONE HYDROCHLORIDE)

Average Rating: 2.8 (229 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

TRAZODONE HCL  (TRAZODONE HYDROCHLORIDE):  This medication is used to treat depression. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.   FDA Approval Date: 1986-10-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on TRAZODONE HCL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRAZODONE HCLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Insomnia I loved this medication for the longest time --but this was before I made the connection to all of these side effects: 1. Weight gain (gained 50 pounds over the year I was taking it. Have lost 30 in the last 6 months of being off of it!) 2. CHRONIC constipation. (I was considering getting a colonoscopy to check for cancer --I'm only 25) 3. Swelling/Water retention (my sister -who is a nurse- used to say I looked as puffy as her edema patients) I cannot believe how long it took me to connect these symptoms with this medication but I feel like a new person since stopping it. F 25 1 years
150 MG 1X day
2/7/2011
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 1  Insomnia I loved this medication for the longest time --but this was before I made the connection to all of these side effects: 1. Weight gain (gained 50 pounds over the year I was taking it. Have lost 30 in the last 6 months of being off of it!) 2. CHRONIC constipation. (I was considering getting a colonoscopy to check for cancer --I'm only 25) 3. Swelling/Water retention (my sister -who is a nurse- used to say I looked as puffy as her edema patients) I cannot believe how long it took me to connect these symptoms with this medication but I feel like a new person since stopping it. F 25 1 years
150 MG 1X day
2/7/2011
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 4  Depression This medication certainly isn't without side effects (but it's been said that any medication that does not have side effects, likely will not work)! Here we go: dry mouth, sedation, improved quality of sleep, constipation, increased appetite, feeling out of it all the next day, increased libido, increased frequency and quality of erections and ability to reach orgasm (no complaints about that one), dry eyes and occasional minor visual disturbances. As with most medications, the side effects are most noticeable at first and when the dose is increased. The good news is that if you take it easy and go up relatively slowly, most of these side effects will diminish with the passage of time (although I'm still going up to a max of 600 so I will likely have to deal with them for a while longer every time I increase the dose). I'm writing this primarily for those that might be researching this drug and are just starting or are considering trying it for depression related conditions. I asked my doctor to consider it since through my reasearch I learned that it was related to Nefazodone (which I did very well on for years before it was pulled from the Canadian market). This drug is classified as an SARI (serotonin antagonist reuptake inhibitor), which is to say that it is both a serotonin antagonist (a lower doses) and a serotonin reuptake inhibitor at high enough doses. This makes the way it works different from any other available antidepressant (except for Nefazadone, which is essentially an improved version of Trazodone that is still available generically in the States (wish it was available in Canada). It's brand name (Serzone) was discontinued after several less than convicing reports of liver failures requiring transplants ( the risk is something like 1 in 250 000 and I would take it again in a heartbeat). Some of the advantages of Trazodone over much more popular drugs such a Prozac, Zoloft, Effexor ect... are that it actuall has no detrimental effect on the quality of sleep (something which the SSRI's and SNRI's definetly mess with). It has a strong calming feeling so it could be good for certain people who struggle with anxiety and have trouble sleeping (it is not addictive or habit forming). Most importantly for me anyway, it has considerably less sexual side effects as compared to m M 42 5 weeks
400mgs 1X day
1/21/2011
 5  unable to sleep about 10 to 15 minutes after taking this I feel slightly dizzy if I'm still standing, but I now take it immediately before getting in bed for the night F 63 13 years
50 mg 1X day
1/10/2011
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 1  Sleep Trouble - Wake in 3-4 hrs Within half hour of taking shortness of breath - like an elephant on my chest. Had to sit up and watch TV for a few hours before I could lay back down and try to sleep Did not help with terrible side effects. I take no other medications that would have contradicted. M 46 1 days
100 MG 1X day
11/30/2010
 5  To help me sleep I can feel a little bit of a hangover in the morning but I think some of that is just the way I am. I always have a tired feeling inside. It works for me. Makes me weary within 15 or 20 minutes of taking it. I've used other sleep medications in the past and those tended to stay with me on into the daylight morning hours which was not desirable. It still happens with this one to some degree but not nearly as much. M 60 4 years
150 MG 1X day
9/19/2010
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 3  Insomnia, Depression. Dependent, dizzy, very vivid nightmares. This drug deffinently does help me fall asleep, but almost every night I have an extremely vivid nightmare that leaves me in a bad mood the next day. I stopped cold turkey for 2 days and didn't have any nightmares...because I didn't sleep. I was rolling around all night trying to get comfortable and it just seemed impossible to fall asleep. I feel very dependent and it's kind of scary, But I am satisfied with how well it puts you to sleep. It really knocks me right out and I usually feel refreshed every morning and not tired during the day. F 18 11 months
50mg 1X day
7/25/2010
 2  Insomnia It left me very, very relaxed which in many people would put them to sleep, but not me. It causes night sweats, which I never get when I sleep. Left me extremely sluggish all day the next day. I was prescribed 50mg for insomnia in attempt to get me off of Ambien 10mg at my request. I also tried Vistaril for sleep, but it was like taking Benadryl and didn't do anything. So needless to say, I'm back on good old Ambien again. F 25
50mg 1X day
7/13/2010
 5  Insomnia Depression worse for about 1 week I am taking 100 mg trazodone, .5 mg Xanax, 8 mg rozerem and 50 mg Imipramine to sleep. I am having to retrain my brain how to sleep again. It made my depression worse for about 1 week but after that I was good on it. I still wake up 2-3 times a night but least I am sleeping 5 hours straight. F 37 2 years
100 mg 1X day
7/5/2010
 2  INSOMNIA STUFFY NOSE STUFFED UP MY NOSE SO MUCH THAT I COULDN'T BREATH THROGH IT THEREBY NOT ALLOWING ME TO SLEEP WELL. F 35 7 days
1X day
6/26/2010
 4  sleep great drug. BUT painful 4 hour erections in the am M 40 6 months
1X day
6/16/2010
 1   F 29
1X day
5/2/2010
 2  Insomnia Drunk and dizzy. Still dizzy the following day! This drug made me sooo dizzy about 30 mins after taking and the entire following day. I gave it three strikes. I do not like this drug at all. It did, however, help me to sleep but not worth the side effects. Give me Ambien anyday. F 35 3 days
100 1X day
3/19/2010
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 5  sleep problems none. First week of my medication I was taking 100 mg and exerienced uncomfortable side effects; dizziness, nausea, daytime drowsiness, stiff neck.. Since then, I break my pill in half and take it twenty minutes before i want to sleep. Trazodone works great, I fall asleep easy and comfortably. Make sure you take this routinely, if I miss a dose I'm a wreck the next day. This drug is also intended anxiety and depression. I've seen minor improvements with that, possibly because of my 6-8 hours of sleep.. :) F 26 7 months
50 mg 1X day
2/28/2010
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 2  Insomnia Added this to my slew of deppression meds..Im on Wellbutrin, Cymbalta and Seroquel. Doc put me on 50mg of Trazodone for insomnia and it didnt work so he raised it to 100mg. I fell asleep but experienced horrible nausea in the morning. I have 2 kids and it felt like morning sickness in the worst way. Stopped taking it..no more nausea. F 28 2 weeks
1/28/2010
 4  insomnia F 50 3 years
12/28/2009
 5  Inability to fall asleep; anxiety None, that I'm aware of, but am wondering (after reading these reviews) if weight gain is one. Am taking other meds, so could be a combination. Have been taking depression meds for years, but started having trouble sleeping following a family tragedy. Have taken different anti-depressants, but stick to one 50 mg. Trazodone tablet nightly, and continue to have good results. I haven't needed to increase the dosage for the same results. I agree with whomever wrote that you need to go to bed within one hour of taking it, though. After that, the effects seem to wear off, and it becomes more difficult to go to sleep. F 65 6 years
12/11/2009
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 1  With Prozac, for sleep I suffered a terrible sleep paralysis incident after taking ONE 50 mg dose of Pliva Trazodone. Been taking Prozac and Trazodone for 12 years and never had this reaction before. Lowered the dose to about 1/4 pill, kept lowering the Prozac, finally had to go off both because I needed them both for either to work. The combination was completely unworkable, I felt like garbage. HOWEVER!!!! The debilitating fibromyalgia I've had disappeared with hardly a trace. I switched to a tricyclic (Watson nortriptyline) and the relief continues. Pliva Trazodone is apparently a whole new drug, and acts entirely different from each of the other generic Trazodone brands I used in the past. F 58 12 years
11/9/2009
 4  For severe insomnia. Dry mouth, foggy feeling in the morning. The side effects haven't been too bad. It has actually made me less of an emotional wreck F 50 4 years
9/27/2009
 4  insomnia At first I had major grogginess throughout the day on the initial 25mg dose. I had to increase up to 50mg after just a few days to get the same effect as the 25mg. I am still kind of new to Trazodone. It's mixed with my cocktail of depression drugs, rls medicine, and an anti-arrhythmic (Wellbutrin XL, Cymbalta, Klonopin, Sotalol). If I don't get to bed within an hour of taking the 50mg pill I pass out on the couch. I'm still trying to train myself to get to bed by 11pm or midnight but I have a lifetime of anxiety around trying to fall asleep and failing. I also have a CPAP machine for sleep apnea that was added just after I started the Trazodone. I wake up several times during the night still and I don't know why. M 39 2 months
9/24/2009

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