VYVANSE Reviews (LISDEXAMFETAMINE DIMESYLATE)

Average Rating: 3.4 (640 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule II   

 Type: Rx Drug

  

VYVANSE  (LISDEXAMFETAMINE DIMESYLATE):  Lisdexamfetamine is used to treat attention deficit hyperactivity disorder (ADHD) as part of a total treatment plan, including psychological, social, and other treatments. It may help to increase the ability to pay attention, stay focused, and stop fidgeting. Lisdexamfetamine may also be used to treat binge eating disorder (BED). It may help to reduce the number of binge eating days. This medication is a stimulant. It is thought to work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. This medication is not recommended for use for weight loss due to the risk of serious side effects.   FDA Approval Date: 2007-02-23 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR VYVANSECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  ADHD PENIS SHRINKAGE, rash, a little anxiety, taking lots of shits. I have to force myself to eat. I have been on and of different meds, sometimes not taking any. Vyvanse helps me focus, and pay attention, but some side effects suck. I'm talking to my doc in a week about the shrinkage, thats the side effect that keeps bothering me. What? Should I go through life motivated and castrated? I'm more confident but side effects blow donkey dick. I weigh 155 lbs and don't get hungry anymore, it got a little better after a couple days though. I also feel anxious like I need to do everything at once, my mind will race but I'll be sitting still. Penis looks dry and shribbled. M 21 5 days
6/3/2009
 4  depression/fatigue due to other dru Initial energy and crash at three hours later. Have muscle rigidity showing as pursed lips, flared nostrils, head tilted sideways, rubbing feet together. Is this dystonia? Lost weight and some insomnia. Depression in AM until I take my first dose. It's been very helpful for fatigue and I do not feel so overwhelmed by life. I am afraid this muscle rigidity may be permanent. This drug works better then most antidepressants. I am on Lamictal, Pristiq,neurontin,ambien,and ativan. Does anyone else have the muscle rigidity and funny movements with their head and feet? Is this dangerous? F 54 3 months
5/18/2009
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 4  Adult ADHD dry mouth, increased jitteriness, weight loss, lowered sex drive, teeth clenching, decreased creativity This drug has actually been mostly beneficial for me. The plusses have been increased productivity at school and at home. Also, before I would want to sleep too much during the day and at night suffered from insomnia. On vyvanse, I am active and focused throughout the day and sleep like a baby at night. I am currently pregnant and unable to take and my mood swings and sleepiness are wrecking havoc. The only side effects from vyvanse that didn't improve with time were my lowered sex drive and decreased creativity. Mind racing can do wonders for brainstorming. All in all, vyvanse has been beneficial and worth taking. I do worry about its decreased effectiveness as your body becomes accustomed to the current dosage level. I plan to return to vyvanse as soon as my child is born. Otherwise I will never be able to keep up with my small children, housework and college studies. F 37 6 months
5/17/2009
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 5  ADD Temporary, mild stomach discomfort after taking daily dose. Clenching of teeth for much of the day, leading to jaw and neck tension discomfort and headaches - all of which Ibuprofen remedies. Dry "mouth" to include eyes and sinuses. Already low sexual desire further eroded. Variously irregular sleep patterns. Occasional bouts of "organizational mania" (as another here said) that lasts 1-2 hours. Decreased appetite leading to weight loss beyond that I have realized from regular physical exercise. Constipation. I started with 60mg/daily and have upped that dosage to 100 after initial ADD diagnosis (at age 45) 5 months ago. The "before/after" differences are astoundingly positive. I now enjoy the presence of focus, patience, planning, listening, awareness of and ability to manage impulsiveness. For example, though having an interest in Buddhist meditation for nearly 2 decades, all previous attempts to "practice" meditation failed. Now, post-Vyvanse, I have taken 2 highly structured meditation classes and "practice" daily for no less than 45 minutes. The biggest benefit is that I can now understand and apply the lessons I receive from therapy, friends, support groups and family. I can not emphasize this last point too strongly, because after 30+ years of living with undiagnosed ADD, I habituated countless detrimental behaviors on top of those directly caused by executive system dysfunction. Nor can I overstate the new found ability to truly relax. M 45 125 days
5/5/2009
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 2  ADHD Insomnia I TOLD my shrink I don't react well to "once a day" pills, and I wanted my Adderall, since I knew it worked. He insisted I try it for one month and see him again. After three weeks I called him back and told him I was stopping it because I hadn't had more than 2 hrs sleep a night for 3 weeks and I was now hallucinating. If you are a "slow metabolizer" this medication is probably not for you. If you are a "fast metabolizer, it may be great. Vyvanse might have helped my ADHD, but the symptoms from the chronic insomnia made it impossible to tell. F 40 3 weeks
4/25/2009
 5  ADD POSITIVE: Increased focus & concentration, deeper sleep, increased bowel movements, happy disposition, don’t feel “drugged”, less worrying (I’m a worrier), no sexual side effects, mildly decreased appetite, no crash when it wears off. NEGATIVE: Dry mouth, dehydration, breakouts at first, amplified hearing with some noises, need to remind myself to breathe deeply, some mild gassiness/cramping, increased blood pressure. Vyvanse has greatly increased my attention and focus at work and home. I am able to sit through meetings, listen to others without interrupting and concentrate on my tasks. I am finally able to fall asleep fast and stay asleep until morning! I have my happy disposition back! I have tried Dexedrine, Methylphenidate, and Concerta, all with very negative side effects (grumpy, easily agitated, zoning out, argumentative, insomnia, headaches, nervousness and overeating.) Vyvanse is by far the best for me. It has been a Godsend! My only concern is the increased blood pressure. I started on 30 mg, which is too strong for me. I now take 20 mg. Perfect! If other meds haven’t worked for you, keep trying! This works for me, another may work for you. Don't give up! F 48 2 months
4/24/2009
 5  Adult ADHD In the very beginning, I had mild headaches, dry mouth,increased need to smoke, weight loss from decreased appetite and more energy to exercise. Insomnia worsened a little bit, but I actually woke up from the little sleep I had feeling more refreshed than usual. Over time, things relaxed and the headaches, dry mouth, loss of appetite, and increased smoking went away, I've never slept well, but waking up more refreshed has been really helpful even if I'm not really getting the sleep I SHOULD be getting. Hang in there, if it's not doing weird behavioral things like rage and bouncy moods, then any other side effects will go away as your body becomes accustomed to it. The appetite loss lasted about a month or 2, then I began to eat normally again. F 28 9 months
4/21/2009
 3  ADD HEADACHE, lite nausea, insomnia bad, amplyfied hearing.taking advil 800 mg to rid the pain. hope it works. go thing it my mind is not racing. My mood has changed for the better and im not stumbling over my words.Yeah! F 29 2 days
4/18/2009
 1  Adult ADD For the three days I was taking it I could not sleep and I felt like I do when I have to much caffine. The first day I was off of it in the evening I felt very depressed and just did not feel well overall. I sleep better that night than when I was taking it but I did wake up during the night with sweats. The next day during the morning I did not feel too bad but by the afternoon I was aggregated. Then later I hit a point I felt really weak and at one point I could not stand. When that stopped I got the sweats, but felt better. This is the effects after taking it only three days. M 49 3 days
4/15/2009
 5  ADD/Binge Eating Disorder Positive - This has CRUSHED my addictions (Food, Drinking, Video Games, Porn -- anything I USED to use to escape life!) Appetite is supressed and I am eating the appropriate amount of calories; have lost 30 lbs without trying because I am no longer binging! I'm focused at work and on conference calls, energetic, enthusiastic, and happy. I am more relaxed and mellow during meetings. My words are not spilling out like before. I'm collected, eloquent, and structured in my team communication. It supercharges me about 1-2 hours after taking and I feel invinsible (but not too spontaneous.) Have had episodes of "organizational" madness where I briefly become obsessed with organizing something (like the mail.) I've never been more productive. Negative - Insomnia can be bad some times (but I'm more productive! Yay!) A few muscle pains very early on. Dry mouth -- no biggie. Completely changed my life for the better! Not for everyone, but worth a try. M 32 6 months
4/14/2009
 4  50 mg daily for Adult ADD constipation (0-2 bowel movements per week), mild to moderate tremor, jaw clenching, tension headache, shouting/moaning/spastic movement during REM sleep, dehydration, loss of appetite, restlessness, increased blood pressure and heart rate occasionally leading to dizziness and shortness of breath, crash involving: agitation, irritability, anxiety, anti-social tendencies and hunger Vyvanse (lisdexamphetamine) is an amphetamine pro-drug that stimulates cytoplasmic release of dopamine (DA) from the dopaminergic neurons in the brain. This activity consequently affects the sympathetic nervous system, leading to increased focus/attention and feelings of euphoria. Stimulation of the sympathetic nervous system causes release of adrenaline, which activates the body's "fight or flight" response and leads to most of the side-effects already listed. Overall, the drug is effective in treatment of ADD/ADHD as it relates to lack of focus and inability to prioritize tasks; however, the typical side-effects of amphetamine use are also observed. M 21 120 days
4/9/2009
 4  possible ADHD, study enhancement OVERALL: decreased appetite, dry mouth, dehydration, sometimes numbness of legs from sitting in one spot for a long time, enhanced OCD-like habits (need perfect handwriting & organization, increased anxiety about small things, etc.) DURING HIGH (1-4 hours after 50mg dosage): felt very happy & social, wanted to work/study, felt jittery, more apt to sweat, anxiety when not engaged in something DURING CRASH (5-9 hrs after dosage): anti-social behavior, extreme annoyance/irritability, either anger or depression (often anger then depression), more emotional I'm a college freshman who went from a 4.0 in high school to a 3.2 in college: kind of normal, but I felt like I was underachieving. I went on Vyvanse to get an extra edge on school, and it worked: it improves your focus & brought up my grades. However, it comes with many side effects. Be careful students: it takes me much longer to finish exams, since I often redo sloppy things and double check everything, even though doing so doesn’t improve my work (sometimes it worsens it). Vyvanse definitely improves your focus, but if you become focused on one thing it's hard to switch to something else (after writing a paper for hours, I want to double check and rewrite parts of it over and over again... it's very hard to switch to studying for biology, for example). Even with all of these side effects, I do NOT want to stop taking it, the improved focus/enjoyment of my schoolwork it brings outweighs all of the negativities. It also doubles as strong coffee: even after an all-nighter it makes me feel awake. As a grade-conscious student, it's kind of my miracle drug. F 18 2.5 months
3/29/2009
 4  ADHD and Binge Eating For the first couple days it was a bit hard to sleep and I felt extremely anxious. I would frequently take deep breaths to calm myself down and wanted to be running errands--that got much better over time, though. Now I only get like that when I drink coffee. I'm not positive, since I've only been taking it for so long, but I think there's a crash period for me. I take it in the morning either at 5:45 (morning practice) or 7 and get really tired around 3-7. I'm just so incredibly happy with this. Everything I've tried has given me a horrible side-effect. Concerta and ritalin made me depressed, and adderall disabled me to sleep and gave me panic attacks. I've read other people's observations of this being a very "smooth," drug. I wouldn't say that it has been for me; it's still definitely a stimulant, and I'm still pretty energetic--just more internally, if that makes sense. F 18 10 days
3/26/2009
 4  ADD, Inability to focus, hyperfocus This medicine has helped me focus quite well and I no longer feel I will get fired because I can't keep up. I've had the decreased appetite, but that's great for me because I am overweight. I have trouble falling asleep or staying asleep. I've had trouble with joint pain, specifically in my upper back and tailbone, probably from sitting at my desk concentrating on work for too long. That has decreased after long term use. I have to force myself to drink water. After taking it for three weeks I've developed an embarrasing gastrointestinal reaction I've heard referred to as "burrito butt." I think that not eating/drinking enough has caused too much stomach acid or something. I'm going to try to drink more and eat better before quitting. I believe that my reactions are out of the norm. This drug has been very beneficial for me otherwise and at this point the benefits are still greater than the cost. I've also taken Ritalin and Adderol, which made me "crash" significantly more. I used to take anti-depressants in conjunction with the others and found that the anti-depressants caused more of the "not myself" feeling than the ADD drugs. I currently supplement with a hefty dose of St. John's Wort to stabilize my mood. F 28 34 days
3/23/2009
 4  ADD Headache, jaw clenching I had taken Adderall XR for a few years prior to Vyvanse. Vyvanse is much smoother and does in fact last longer. M 29 10 months
3/20/2009
 1  ADHD CLENCHING OF TEETH DRY MOUTH ,UPSET STOMACH ,I GET ANGRY AT THE LITTLEST THINGS, THEN OUT OF THE BLUE I WILL START TO CRY FOR NO REASON. I AM VERY JITTERY LIKE ON SPEED , INSONIA ALSO , I HATE FEELING THIS WAY !!!! I WIL NOT BE TAKING THIS STUPID EXPENSIVE MEDICINE I AM A 47 year old that really wants to get the best out life.i will be going back to the dr. to be relieved of this poison.I want enjoy sex,i want enjoy life without dealing with horrible side effects from meds. i know there is one out there somewhere F 47 7 days
3/19/2009
 2  adhd extreme irritability, rage episodes My son also has depression. Thanks to the side effects of the vyvanse he is now in residential treatment for violent rages. 3 days into treatment they DC'd the vyvanse. Increased anger is a known side effect of this med I found out. M 10 6 months
3/16/2009
 1  
3/9/2009
 3  ADHD/DEPRESSION/ANXIETY/DISLEXIA UNTIL NOW THAT WAS READING THE COMMENTS; MOOD SWINGS,DIFFERENT BOY; ANSWERING BACK,TEASING, NAME CALLING. I THOUGHT MY SON WAS DOING FINE WITH THIS NEW MEDICATION (VYVANSE) BEFORE HE TRIED EVERYTHING NOTHING WORKED 4 DIFFERENT MEDS HE IS DOING BETTER BUT I SEE A CHANGE IN ATTITUDE HE IS VERY DEFIANT HE DOES TAKE CLONIDINE 0.1MG AT BEDTIME AND A VITAMIN EVERY MORNING SO HE WOULD BE HUNGRY DURING THE DAY. M 10 8 months
3/7/2009
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 4  add/dyslexia My son is 9 and lost 10lbs since December. But his studies are great. No arguing during homework. But you do have to watch the mood swings. He does have that once in a while. We are going to decrease the dosage to 50mg because he is still losing weight. M 9 3 months
3/2/2009

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