Average Rating: 3.0 (42 Ratings)

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Compare AMITIZA with similar:

 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 3  Ibs-c chronic painful constipation. Peeing outta my butt at first, starting to level out after day 5. Bad headaches, some dizziness and cramping. I took this because Linzess didn't work at all. OTC stool softeners and laxatives don't work well either long term. This seems ok so far. Fingers crossed. Give it time? Look into diet too, not a "fix-it-all" type pill. F 44 5 days
24mcg/day 1X D
 4  Ibsc 2 a day caused diarrhea, horrible gas pains & vomiting about 1X a month during diarrhea F 74 0 months
24 mg 1X D
 1  Chronic Idiopathic Constipation I had no side effects. This drug did not work for my constipation. I took 2 a day, gave me diarrhea. Then did 1 a day. Still nothing. Added 2 dosages a day of miralax with it, gave me diarrhea. It gave me 1 BM in 6 days. Very disappointed with this drug. F 57 14 days
24 mcg
 2   None Worked well at the beginning, after 3 or 4 days I was back to suppositories. M 83
2X D
 5  Redunted colon lazy bowels None I take one in morning then hour later bm the one I take in evening will not work I would like to know why it does not work in evening I would feel much better please write back M 67 6 years
24 mg
 1  Chronic Constipation Nausea and dizziness I started slow with one pill before I added the 2nd as I didn't know how it was going to work. Well I just didn't feel well from day one of taking it. I started getting mildly dizzy but only seemed to show up when sitting. I continued as it did help some and hoped side effects would go away or I could handle them. Nope! Dizziness increased. So at about 3 wks I stopped taking it. That was 2 wks ago. The nausea left immediately but I am still having a terrible time with the dizziness. Never was dizzy before this. F 57 3 weeks
8 mcg 1X D
 2  Bowel resection / non working colon I have had bloating, extreme dizziness to where it's affecting my everyday life! Have had to go to the ER already was taking with Relistor shot as well every other day. I have stopped everything except the Amitiza, Miralax, colace, senna laxative, now I'm on meclizine but it's not helping! I've been bloated having heartbeat in my head ! This is very bothersome the Dr said its meds or a bag ! Any opinions or input ? F 40 3 weeks
24 mg
 4  Constipation None Stopped taking because of its expense. Now, every morning I mix one teaspoon of baking soda in 12 ounces of water and add the juice of 1/2 of a fresh lemon. At night take one 1,000 olive oil extract pill to keep insides hydrated. This combination works just as well as Amitiza and it only costs pennies compared to $4 a pill for Amitiza. F 59 2 years
24 2X D
 3  OIC Severe bloating, distention, and super dry mouth. Occasianal nasea, but that could be from other meds. When you take 4 or 5 meds, it's hard to figure out which is causing what. This week had a huge dry compacted stool. I drink 10 16 oz bottles of water daily and exercise seemed to work great, now not really M 48 10 months
24 mcg 2X D
 3  Opioid Induced Constipation I've been experiencing nausea when I first take the capsule then it subsides after a couple hours, then nausea reoccurs after night dose. Still waiting to have my 1st.Bowel movement, then maybe I wouldn't mind the Nauseated feeling I get. F 51 2 days
24MCG / 2
 5  chronic constapation Zero. Most normal I have been. I have tried it all. I take two at night. No cramping, no loose or messy BM. No pain, no headaches, zero problem. I say, try it, as I have tried everything recommended by doctor and old remedies. F 67
2X D
 3  medication-related constipation Chest tightness, mental fogginess, fatigue In 45 days I've had three spontaneous BMs. I continue to experiment with additional measures, based on MD recommendations. Currently I also take 2 to 4 magnesium tablets/day; 3 stool softeners; 5 soluble fiber capsules with lots of water; 2 sennas (at night); and use 1 or 2 suppositories. I've had only 1 spontaneous BM in 45 days that was "enough," so I used a suppository even after the other 2, producing an equal amount on the 2nd try. I'm highly motivated, as the medication that produces constipation gave me a large+small bowel impaction this summer, which turned into an obstruction, and I had to take Supraprep via nasogastric tube in the ER to clear it. I'm disappointed that Amitiza isn't very effective, and worried about my quality of life if I keep being unable to concentrate very well. BTW, the web page e-mail address is required ONLY if you want to be able to edit comment or be contacted by others, but the Review button won't work unless an e-mail is entered! F 69 45 days
24 mcg 2X D
 4  constipation it helped the 2nd but had bad cramping i took one the 3rd and now off as of 5 days ago i still have watery stool is this normal help plz F 37 3 days
24 mg
 5  Unknown severe constipation I started taking 24mg once as day but gave me severe nausea and almost like a was gonna pass out I had to sit crouched over in the floor for about an hour and a half to two hours it did this twice so I stopped taking it and called my doctor, he said try 1 every other day, so I did but it did the same thing. I called back and he said to stop taking it and started me out on 8 mg. even with the first dose I have a bowl large by everyday. I have to take it on a full stomach it just makes me gassy if I take it on an empty stomach it makes me severely nauseas. I know take 8mg a day on a full stomach doesn't matter if it's in the afternoon or at night. I went from no bm for 7 days at a time, tried linzess, miralax, stool softners, laxatives, and none of them worked. Amitiza so far is the only thing that helps. I have daily bms now no more stomach swelling and most of all no more constipation!! F 24 1 months
8mg 1xd
 2  constipation Helped with her idiopathic constipation. . But caused horrible chest pain and tightness. Shortness of breath. F 10 3 months
30 mg
 2  pain mgt patient narcotics=constipation was so hopeful it would work. second day I started to get dull headaches, nothing I couldnt deal with. 5th day still havent gone and It was 13 days total. 6th day dizziness set in just slight. 12day dizziness consuming my life. Stopped immediately. Never had bowel movement w Amitiza without using laxative The copay of new drug would have bn worth it if the drug worked. so dissapointed. F 56 2 weeks
24 mg
 3  Gluten intolerant,chronic constip. occasional shortness of breath, achy joints, bloated feeling, diarrhea, occasional headache When I first started taking amitiza it would make me bloated and full feeling. Sometimes I would have a bowel movement, sometimes not. If I did not it was a pretty uncomfortable feeling most of the day. I did have the shortness of breath a few times. I was taking it twice a day as recommended. It was brutal in the beginning. I was desperate though, from the discomfort of the constipation. I started reading about how the medicine worked and started my own trial and error of the best way to take a dose. I stopped the twice a day for one because it made me feel terrible all day and evening. Eventually I stopped taking it with food early in the morning, and would take it with a cup of coffee. In 1-4 hours I would have a bowel movement. It was usually just diarrhea, but it relieved my constipation, and I generally felt better. I have been taking it off and on for several years now, and I know this; if I take it on an empty stomach, it works better. I drink a bottle of water and generally a cup or two of coffee. It's difficult to have to wait around in the morning for a bowel movement, especially when it comes on the way this medicine brings it on. What I have begun to do now is set my alarm and take the medicine about 2 hours before I get up in the morning. It seems to work. I get up, and within and hour I'm going to the restroom generally. I try to eat pretty quickly, and it usually makes my stomach feel achy for a little while after, but it's much better than feeling aweful for M 38 4 years
24mcg 1X D
 1  Chronic Ideopathic Constipation Severe Nausea, Sometimes Leading To Vomiting After Dosage, Acute Cramping, Gas, Severe Spasms In Colon, Aching! Sometimes Takes 1 Hr To Work But Lately 3-4 or Even A Greater Amount Of Time For Results Of Severe Watery Diarrhea, 3-5X Each Day! The Waiting Is Exacerbating And Extremely Painful NOT TO DOWNPLAY The Bloating And Gas Which It Doubly Uncomfortable! Then, The Actual Bowel Purge, Itself Causes Great Dehydration, Exhaustion, Spasms, And Aftermath Pain! This Super Strength Laxative, Is Worse Than A Colonoscopy Prep, As It Works Very Unpredictably, Is Mostly Unreliable And Leaves One Utterly Fed Up! I Find Myself Wondering, Why I Am Putting Myself Through This Torture! The Nausea, Spasms And Pain, Truly Bring me to the point of Needing To Vomit, To Get Some Relief Of The Bowel Pressure, And Nausea Occasionally, I Do, But It Rarely, Brings Great Relief! Same Said For The Bowel Purge! Major Bouts Of Watery Diarrhea! Seldom, Formed Stools! Regimen Seems To Take Up 4-5 Hrs In The Morning Until Noon! Very Dissatisfied! This Is Like Prepping W Poison Or Dynamite! 😷 I Want OFF This Bomb , I HATE IT! 😠 Thanks For Putting Yet Another Drug W Horrible Side Effects, Which Cause The Individual Who Has No Other Alternative, Due To "Chronic Idiopathic Constipation " From " Chronic Inflammatory De-Mylonating PolyNeuropathy-CIDP" WORST DRUG W Side Effects That Is Currently On The Market! Please Develop A Better And More Gentle Pharmaceutical Alternative, My Father Is Seriously Suffering From All Amitiza Side Affects And It Has Only Continued To Raise Havoc For Him Each Day Of His Essential Bowel Purge! Acute Spasms, Pain, Severe Nausea, Vomiting, And Bloating From Distention, There Must Be Another Way! This Drug Appears To Be Counter Intuitive To It's Desired Goal, Thereby Causing Greater Spasms, Acute Pain And Severe Nausea That Often Causes A Worse Bowel Purge, Than An Easier, Less Torturous Manner Of Side Effects, That Ultimately Cause The Individual, To Feel Better, Not Worse From Daily, Unpredictable Use! It Is Difficult As A Spouse And/Or Care Provider To Witness Such Acute Symptoms And Severe Intestinal/ Colonic Pain And Discomfort Of Individual Taking This Harsh Drug! Please Work With The FDA To Explore Less Toxic Options And Less Undesirable Side Effects while Still Achieving This Type Of Drugs Ultimate Goal! Thank You! Concerned Family Member, And Patient Advocate! M 78 2 months
 2  Chronic constipation I developed an infrequent dry cough on Amitiza and it hadn't started working afte 2 weeks so I stopped using it. I had been constipated for about 10 years, since moving to Florida. One day I saw rust stains in my toilet after returning from vacation and realized there was a lot of iron in my water. I know iron can be constipating, so I added a type of salt to my water-softener that takes the rust out. Since then I am no longer constipated. Perhaps doctors should ask about iron in water before prescribing Amitiza! F 61 2 weeks
24 mcg 1X D
 2  Chronic constipation Nine in low dose. Higher dose, more bloating, chest and throat tightness, wires dry mouth, belching more This has done absolutely nothing to help my constipation. If I take Miralax, I gave a small BM in the morning. Doctor says to give it a chance to work. It's been a month and almost 2 weeks at the higher dose. I feel worse than I did. I want off this drug. F 64 28 days
8 mcg & 24 2X D

AMITIZA  (LUBIPROSTONE):  This medication is used to treat certain types of constipation (chronic idiopathic constipation, irritable bowel syndrome with constipation). Chronic idiopathic constipation has an unknown cause and is not due to diet, other diseases, or drugs. Lubiprostone is also used to treat constipation caused by narcotic (opiate-type) medications in people with ongoing pain due to medical conditions other than cancer. This medication may improve symptoms such as bloating and abdominal discomfort, improve stool texture, lessen the need to strain, and decrease the feeling of not completely relieving oneself. Lubiprostone belongs to a class of drugs known as chloride channel activators. It works by increasing the amount of fluid within your intestines, making the passage of stool easier.   (Sources: U.S. Centers for Medicare Services, FDA)