VYTORIN Reviews (EZETIMIBE; SIMVASTATIN)

Average Rating: 2.4 (57 Ratings)

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 Type: Rx Drug

  

VYTORIN  (EZETIMIBE; SIMVASTATIN):  This combination medication is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Simvastatin belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.   FDA Approval Date: 2004-07-23 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR VYTORINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  dr. said was safest/no side effects horrible muscle cramps in legs, itches, ulcerative proctitis, myalgia, cellular damage in lower leg muscle disclosures said muscle pain or muscle ache; so dr. and pharm. didn't recognize cramping as symptomatic M 62 6 months
4/12/2008
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 4  High tri/col. Been on vytorin and trycor 145. Wasn,t sure which one was giving me the muscle pain in my back,legs, and making me so tired.So I just stopped the Trycor 145 3 days ago and I'll see if pain goes away...I stopped trycor 3 days ago and already feel better. Must say the combo of Trycor,vytorin,niacin with fish oil lowered all my levels very, very well...but think I'll go without the Trycor for now.. M 59 2 years
4/3/2008
 1  high overall cholersterol started out as itching, progressed to excruciating burning pain, neuropathy, over a period of 3-4 years This stuff is a death sentence for some people - one neither the patient nor doctor sees coming because it sneaks up on you. There are thousands of sufferers and the doctors don't recognize it. This will be the next major drug scandal. F 60 4 years
4/1/2008
 2  lower cholesterol muscle and joint pain does lower numbers, but no benefit for heart problems, drug companies knew this 2 years ago! read news release http://ktla.trb.com/news/ktla-vytorin,0,42072.story In Canada this is called ezetrol M 50 1 days
3/31/2008
 1  High Cholesterol Worst side effect was burning sensation in neck arteries and elevated liver enzymes. Vytorin, which came out in 2004, combines Zocor with Schering-Plough Corp.'s Zetia, which went on sale in 2002 and attacks cholesterol in a different way. The study tested whether Vytorin was better than Zocor alone at limiting plaque buildup in the arteries of 720 people with super high cholesterol because of a gene disorder. The results show the drug had "no result — zilch. In no subgroup, in no segment, was there any added benefit" for reducing plaque, said Dr. John Kastelein, the Dutch scientist who led the study. That happened even though Vytorin dramatically lowered LDL, fats in the blood called triglycerides and a measure of artery inflammation — CRP. M 63 1.5 years
3/30/2008
 2  High Cholesterol Pain in lower back on both sides by kidneys. Pain just under my left shoulderblade. Feeling of stomach bloating, waking up soon after sleeping with pain in my chest that felt like a heart attack. Acid reflux. One episode of my vision being wavy on the periphery. 2 upper respitory infections in the last year I thought I had cancer. I had no idea what was wrong with me. My doctor ordered 2 CT scans which were both negative. I thought my mind was making up all these symptoms. Then I looked closely at the side-effects, did some searches, and found others had the same side effects as me! Realized that my cardiologist had prescribed Verapamil with high-dose Vytorin, which it specifically says one should not do! Amazing! and he's a doctor. I have stopped taking Vytorin about 5 days and the pain in my lower back is beginning to subside. M 38 2 years
3/23/2008
 2  high triglicerides and cholesterol extemely dry mouth, to the point of having a constant feeling of sickness Dr. switched me from crestor 20 mg which I had been taking for approx. 4 years due to an increase in triglicerides F 46 4 weeks
3/21/2008
 4  High Cholesterol and Triglycerides None that I could notice Worked very well lowering my total cholesterol in half, from about 285 to about 140. Did not do a very good job lowering my triglycerides, nor did it improve my cholesterol "ratio" in a significant manner. I am taking the lowest dosis available for both drugs in the product. M 64 14 months
1/31/2008
 4  high cholesterol joint pain, back pain, insomnia, cough, sore throat, runny or stuffy nose, and headaches at times. Not all side effects all the time but some more than others and some more often. It's helped my cholesterol levels greatly and without it my cholesterol levels were 250+, now around 180. M 44 1 years
1/27/2008
 4  High cholesterol None Added Vytorin 10/20 to my Omacor 4 caps a day regimen. LDL went down significantly. M 37
1/18/2008
 1  Very high cholesterol Atrial fibrillation w/ER visit; muscle/joint pain Statin drugs seem to work well for some, but there are some who ABSOLUTELY should NEVER take any of this class of drug. Some of the side-effects can become permanent damage. Do the web research, there are tens of thousands out there for whom this drug is much more harm than good. M 50 4 months
1/18/2008
 3  High Cholestorol Muscle pain and ache feels like circulation has been cut off from my lower legs It has helped lower my over all counts F 43 5 years
1/17/2008
 2  high cholesterol burning feet, started off I thought I was just standing too much but over time the burning got worse M 39 90 days
1/14/2008
 5  high cholesterol Occasional joint pain but not sure it is attributable to Vytorin I have taken Vytorin for 3 years. My Cholesterol reduction has been substantial. Total 250 start; 103 as of 11/07. LDL 179 start; 53 now. TRIG 167 start; 87 now. HDL 38 start; 34 now. M 63 3 years
12/5/2007
 1  High Cholesterol Muscle and joint pain, nerve inflamation, memory loss and mental confusion, hair loss, unexplained weight loss, elevated liver enzymes. Criminal M 63 1 years
11/14/2007
 1  High LDL Aches pains, nagging ache between shoulders Healthy diet I hope will cure this! F 45 3 weeks
11/5/2007
 1   produced lupus syndrome, joint pain, muscle ache, etc M 67 5 years
11/2/2007

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