EMSAM Reviews (SELEGILINE)

Average Rating: 3.6 (65 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

EMSAM  (SELEGILINE):  Selegiline is an antidepressant (monoamine oxidase inhibitor) that treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain. Selegiline can improve your mood and feelings of well-being. This medication is a patch for use on the skin.   FDA Approval Date: 2006-02-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4


RATING  REASONSIDE EFFECTS FOR EMSAMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression localized acne/skin irritation. difficulty with orgasm. the first drug that's actually helped me with my depression! M 52 3 months
24mg 1X day
7/26/2010
 3  Depression Massive bruising, rashes& itching on thighs when placed there. Itching, swelling & redness where ever else I placed it. Also, a lot of problems keeping it on (would slip/peel off). All of the topical allergic reactions I am experiencing are really a shame, because the actual drug seems to be effective in treating my depression!! :( F 39 6 months
12.5 mg 1X day
7/23/2010
 5  treatment resistant depression insomnia, some difficulty with orgasm, but still attainable has changed my life- I have my life back and feel like my old self once again, it's been 3 years of trying everything else with always intolerable side effects. F 49 2.5 months
6mg 1X day
4/20/2010
 1  Depression The patch left marks on my chest een after 30 days. In addition my heart rate become even more irregular and pulse was low 42bpm then at the normal Brady Cardia rate 58bpm. Dr's were considering a pace maker. Emotionally I was not much better either. Discontinued Emsam and heart returned to normal as test by Dr. in a running stress test. So Emsam can have heart rate impact for certain people. M 60 45 days
10/4/2009
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 4  Major Depressive Disorder with GAD Site specific irritation, scarring eventually- accept this cosmetic issue over insanity/suicide. able to tolerate patches on my outer hips (more fat there?) better than stomach or back application. Overall, more insomnia, but of different style- can be overcome w/ mild sedative (doc chose Sonata), good sleep hygiene/routine. slight manic effect of patches. Can't tolerate the 9mg ones- went crazy anxious manic on those. at 6mg\24. Have noticed significant weight gain over last 2 years, despite increasing activity (running again for first time in years!). Going to try more weight training to see if that helps- at least stops weight gain, even if no loss. Was incredibly happy on Serzone (SSRI) but it was removed from market (though my regular tests showed no liver damage/other side effects). However, given my cycling onset of depressive episodes, SSRIs are not as effective (Cymbalta was @1st,then crazy rapid weight gain, doc took me off it). The continuous, transdermal dosing of the patch is what has kept Depression at bay. Though i am "depressive" (melancholic?), therapy and ongoing behavioral mod, especially working with thoughts/thought patterns, and EMSAM has meant I have not had a major crash since 2005. Like someone else said, it's like a "safety net". No negative effect on libido; restored ability to orgasm (though it does effect "how" they feel- if that makes any sense). F 41 3 years
9/25/2009
 2  severe depression Insomnia, homicidal thoughts not related to my illness--these were new and disturbing. Caused frequent urination I was already having with Interstitial cystitis to get worse. I was up all night and up to pee 6-7 times. No thanks. I wish I'd have had the luck that other people have. Instead of giving it a 1, I gave it a 2 because I think people with severe depression should be encouraged to at least try something to improve their lives. I couldn't shake the insomnia for anything and my dr. wanted to add Zyprexa so I could sleep. He didn't believe it made my IC worse and didn't believe it gave me homicidal thoughts. Oh well. I have tried nearly EVERY anti-depressant out there and just struggle with therapy. sigh. F 36 2 weeks
6/19/2009
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 5  bipolar (rapid cycling) For the first 6-8 months after I began taking EMSAM I experienced severe acne on my upper trunk and arms -- a shock to the system of a 45 year old man who never had acne before. However, this very unpleasant and disturbing side effect diminished considerably by the end of the first year. Oddly, I found that once I limited application of the patch to my back, and no longer applied it to my chest or upper arms, the acne diminished. I also experience some insomnia, of a different and less disruptive sort than I experience when I am having bipolar episodes. The insomnia is usually quite manageable only occasionally disrupting my daily functioning. Also, though it may be unrelated to the EMSAM and more related to the discontinuation of my previous medication, I note that I have gained significant weight(going from 165 pounds to 210 pounds)since starting the EMSAM although my diet and exercise routine are unchanged or better than they were before. I was diagnosed with bipolar disorder (rapid cycling) nearly 20 years ago. I have been on dozens of medications (all the usual suspects), abandoning each in turn for lack of efficacy or intolerable side effects (e.g., toxicity, dramatic weight gain, loss of bladder control, excessive sedation, mental dullness or confusion). My doctor finally prescribed EMSAM, in combination with Lamictal and Deplin, and I am thrilled to report that is the first regime that has had any modicum of long-term success (now 18 months) in the treatment of my bipolar disorder. The bipolar episodes are much more muted, of shorter duration, and far less frequent than they were with any other medication regime. As the side effects are very tolerable compared to the other medications I have used and the efficacy quite high, this is a "miracle" drug for me. If only it worked so well for everyone! M 45 18 months
5/31/2009
 5  severe depression some difficulty staying asleep. Mild skin redness under patch that lasts for about 24-36 hours after the patch has been removed. I have VERY sensitive skin though. This medication has given me my life back (and probably saved my marriage!). Over the past 35 years I've been on just about every antidepressant made. The side-effects were always unbearable. Major anxiety on the SSRI's, complete insomnia and horrible paranoia on tricyclics. From the moment I put the patch on there were no unbearable side effects or really any adjustment period. Then with each passing day I started to feel more and more "normal". It was gradual, and after about 3 weeks I realized I no longer felt like I was walking through mud every day in order to function. My attention and memory increased. My over-all mood improved. I no longer got irritated about things I used to get irritated with. I've been in therapy for years and at best I was only able to "maintain" in therapy. Having my depression lifted has allowed me to move forward with my therapy. I know everyone's body is different and this drug won't be the "miracle drug" for ev F 50 2 years
11/12/2008
 5  MAJOR DEPRESSIVE DISORDER Slight sleeping problems depending on dose...either sleep too much or not at all but thats basically normal for me whether on meds or not. Higher dose seemed to bring on a little anxiety & irritation but it didnt last after adjusting to it. When you increase or decrease a dose you have to remember that it may take a little time for your body to get used to it, if you get side effects they might go away if you're patient enough to wait it out a couple weeks. Everyone reacts differently to everything...Emsam happens to be the one thing that has finally worked for me after years of trying numerous meds. But yes i still have to try hard to maintain a normal lifestyle because there is no such thing as a perfect miracle pill, but this has totally made life easier, better, & more content. Especially considering that before i used to have suicidal thoughts constantly & cried all the time, since i started the patch those have basically disappeared!!! YAY! I really hope you find the same relief, whether its from this drug or not. :) F 26 3 years
11/6/2008
 1  Atypical Depression Daily site-specific skin reaction to 6mg patch. Increased to 9mg for depression symptoms. Severe skin reaction under patch turned to severe auto-immune response (body-wide hives, welts, severe itching)within 4 days. Immediately stopped using Emsam, but required 2 weeks steroids to subdue hives. Also experienced insomnia on Emsam...any possible therapeutic effects got lost in side effects. Will try oral selignine next. If that doesn't work, next step is monastery in Nepal. M 57 3 months
9/21/2008
 5  depression At first did not work well because I didn't figure out how to apply it. This has the least amount of side affects than other med I have tried. Cant sleep at night, So some times I just take the patch off at night and put a new one on it the morning. I have found out that you must apply this patch one way only for it to work well. 1. I use hydrogen peroxide on my skin were you are going to apply it. It does not dry out your skin. 2. Your upper chest or middle of outer arm works well as the patch will not crease or fold as you move around. 3. You have to take the small peace of plastic off first and stick it to you skin. Then take the big peace fold it over to the other small peace and press and move it down tell it comes off you may have to try this a number of times before you get it down. There should not be any creases in the patch or bubbles for it to work good. Hope this helps every one having trouble with the patch, I think it's the best product out there for depression if applied wrong it wont work as well if at all. M 30 4 months
6/9/2008
 1  depression Don't even bother trying it. Was neutral in terms of mood and just gave me intolerable insomnia and a chronic urinary tract infection. Went off it 2 weeks ago and I STILL can't sleep The cure is worse than the disease. F 45 60 days
6/7/2008
 2  Depression Headaches that would last 1-3 days with no relief. Insomnia. I started with the 6mg patch and worked up to 9mg. During this 2 month span I had about 3 episodes of severe migraine-like headaches that lasted up to 3 days. Made work unbearable. Mild insomnia. Did not help my depression but could not give it longer time due to headaches. I did almost fall over once getting out of bed due to the drop in blood pressure effect from MAOIs. F 33 2 months
3/3/2008
 5  Bipolar Disorder Some hypomania/mania and insomnia, see explanation Emsam was a wonder-drug for me. I believe it worked better than all the SSRI's and tricyclics I have tried over the last 15 yrs. My theory, the MAOI (Emsam) catches your depression BEFORE you can free fall into a full blown one, like a trapeze artist's safety net. For the mania side effect, my doctor decreased the patch (9mg) to every other day--worked great until I had some depression and anxiety over starting a new job. Then we went back to every day. Then some insomnia started, and I asked my doctor about removing the patch 2-3 hours before sleep. He thought that was a great idea and it worked like a charm. Sadly, I have to give the patch up as the lithium that I've been taking for almost 6 years, has shown some lousy side effects. However I praise lithium to the hilt--I initially lost 35lbs on lithium. I am soon to start tegretol as a mood stabilizer and you can't be on an MAOI with that. If it works as well as the MAOI, I'll be thrilled. Talk to your docs about ways to ge F 51 16 months
1/30/2008
 5  treatment-resistant depression There have been few side effects that have bothered me: dry skin and a red mark that persist for 12-36 hours after removing a patch, the fact that the patches will fall off if I am too sweaty or the skin flexes too much (mostly with exercise), and a worsening of the dry eyes that I’ve had since my Lasik procedure in August of 2006. I’ve found that I can minimize the first two issues by washing thoroughly with soap before applying a patch, and by washing and using lotion after removing it. A doctor at the clinic where I had my Lasik procedure was able to prescribe Restasis eyedrops, which have eased the dryness back to its pre-Emsam level. I've been dealing with depression for about 15 years, and have tried almost everything; I've been on somewhere in the neighborhood of 20 different antidepressants, had 8 hospitalizations and 3 separate series of ECT. Nothing worked for more than a few months at a time (aside from the ECT, at up to a year), if it worked at all. I was finally talked into trying something in the MAOI family of drugs in May 2006; I’d hesitated because of the dietary and drug-interaction restrictions. I noticed – somewhat reluctantly – a gradual improvement in my mood in the first two weeks of taking this medication. My mood continued to improve until reaching something resembling stability in July or August 2007, and has remained there – more or less – since. To quote a journal entry of mine from July, “…it seems just a little easier to do what I need to do, and things don't seem as hard as I remember them being before. I'm not worrying about things as much, a F 27 8 months
1/22/2008
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 5  SAD,ADD,and life extension the first couple of weeks I had a pick me affect and better concentration. sleeping was not sound until after two weeks. I had been in wellbutrun sr for the last cuople of years and very much liked that med. But when emsam came out i tried to get my doc to prescribe it for me, finally he gave me the prescription last month. I used to order liquid deprenyl from England. I will take this med and life extension med for life and living longer. look up IAS for more info M 56 15 years
12/15/2007
 5  depression *Mild application site reaction - dry skin, reddness / discoloration. Itching goes away after 12-24 hours of removing the patch. Discoloration lasts around a week before it fades completely. *Insomnia - mostly difficulty falling asleep, occasionally difficulty staying asleep. Haven't found a solution yet, but my doc is exploring the idea of sleeping meds with me. Neither of the above side effects are anywhere near severe enough to warrant going off of this medication. None of the 7 other antidepressants I've tried have ever touched my depression. Emsam has given me an almost complete remission. I feel more motivated, have more energy, and my overall mood has improved significantly. I'm less irritable, my self esteem has improved and I'm back to doing things I like, hobbies and seeing friends and such. It's not an instant cure, but it's truly made a difference for me. F 32 9 months
11/26/2007
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 3  general depression with hypomania Skin irritation from patch, extremely itchy, red and sometimes raw, marks remain for nearly 2 weeks. Lack of motivation, and it deadened my creative energy and imagination, especially at full 6mg dose. Also terrible insomnia at 6 mg/day. General skin irritation and breakouts, and frequent cold sores. At full 6mg/day dose, had unusually high libido but difficulty reaching orgasm! Still not sure about this stuff after a year! I've cut back to half a 6 mg. patch for half a day every other day (less than 3mg a day) and still feel that it keeps me from sinking all the way down when I start to get depressed and anxious. It lifted the general depression that I was under most of the time for years, made me feel like it was worth being alive after all. Also makes me less hypersensitive and emotionally reactive to everything, which is good in some ways but not in others. I've got my imagination back, which I needed since I'm a writer. I'm not sure if it's still affecting my sleep at this dose. But I still feel completely unmotivated to do daily things, can't keep track of things at all (like bills and finances), have some memory problems and mix up words a lot. I don't get anxious about the future, but I can't make plans, either. I had some of the same problems on Celexa: couldn't think clearly and didn't care enough to worry about all the stuff I was messing up. Still F 50 13 months
10/5/2007
 2  DEPRESSION NONE Felt a buzz the morning of the 2nd day, but do not believe its doing much now. I am at 6/24. M 54 19 days
9/27/2007
 4  Atypical Depression/ Panic Disorder Took 3.5 weeks to get any benefits at all. At that time, the panic attacks went into remission for a couple of days and then returned intermittently for a week until I contacted the doc. Upped the dose to 9mg patches at that point. At 9mg after 4 days I began to have a hypomanic onset of anger and hostility. Also had a marked increase in energy which I really liked. Have been having to mix the 6mg and 9mg patches back and forth every few days to keep out of depression/panic on the bottom end and out of hypomania on the top end. Note: I e-mailed a doc that assisted with the research of EMSAM, turns out that you CAN cut the patch safely and so I have started doing so. Jury is out on the exact amount I need, I am guessing 8mg. I had almost given up at 3 weeks, but am happy now I didnt. The one thing it has not helped with at any dose has been the generalized anxiety but that is usually a GABA related issue and I wouldnt expect EMSAM to help that. Also, lost weight and began a great workout routine due to the stimulant effects at a higher dose. Started it 12/23/2006 and am still using it today. Overall it is the second best med I have used through the years (I have been on 27 different ones in 15 years) with Celexa being the best but lost its punch after about 3 years. M 34 9 months
9/19/2007
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