DEPAKOTE ER Reviews (DIVALPROEX SODIUM)

Average Rating: 3.2 (181 Ratings)

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DEPAKOTE ER  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 2000-08-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPAKOTE ER: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTE ERCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Daily Migraine I have not started taking it yet and am going to start today but I noticed that most of the posters on here were women. My Dr whom is a very respected headache specialist told me WOMEN SHOULD NOT TAKE DEPAKOTE. Please fully investigate as I read alot of negative reviews and after seeing hack DRs for years I realized one must really see a specialist and do much research ones self. Hope that helps. Do your homework! M 24 0 days
10/3/2006
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 3  Bipolar Weight Gain, Aggressive towards others This medicine the first few months seemed to work for me other than Weight Gain. Towards the end I became very unpleasent to be around bitching at everyone for everything. Would get in fights for virtually no reason and this was very uncommon and unlike my normal behavior before hand. F 27 5 months
9/21/2006
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 1  bipolar I took 1 pill of this and poured the rest down the toilet. The very 1st pill made me feel so much anxienty, panic.. and traumatic emotional overload I wanted to die.. Total fear and lost of emotional control. I also vomited. It gave me faint like feelings, trembling and cold sweat and chills. I'll never take it again. M 35 1 days
9/13/2006
 1  Headaches from a car accident Major hair lost I am losing in hand fulls everytime I touch my hair. My bed is full of my hair and my clothes. I am starting to bruise without reason easily. Tired all the time, some days I do not want to get out of the bed I would not recommed this med, I am going to stop taking it F 34 6 months
8/12/2006
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 5  bipolar don't have any F 26 3 weeks
8/8/2006
 2  migraines tired all the time sems to have made the side effect from topamax worse been on topamax 200 mg twice a day for 3 years headaches much worse. depakote 250er was added will increase to500mg. headaches only slightly better but hungry all the time, depressed and TIRED F 43 30 days
8/6/2006
 1  rapid cycling mixed bi-polar It cut off the good moods but worsened the depression. In a matter of minutes, I will feel suicidal. I'm tired all the time, but have horrible nightmares. My shoulders and elbows hurt constantly. Didn't help with anxiety at all. I feel like a zombie. The first month, I vomited, tinnitis, shaking, always felt cold or hot. I have taken everything else and nothing works. This was the last option. I think I'd rather have mood swings than this constant depression and lethargy. Libido is almost gone. Most of the side-effects I have had aren't listed and the doctor doesn't seem to believe me, although I'm on no other drugs. I've really tried to make this work, but I'm giving up on it. My friends say it seems to have made me even more depressed and I'm never happy anymore. I suddenly cry for no reason. My skin itches and I'm going to stop taking it. M 46 1 years
7/8/2006
 5  Seizures Increase in appetite (hungry under two hours after eating), hair loss (head), body hair growth (back), slight memory loss, occasional stumbling over words when speaking Switched to ER for convenience of not taking pill mid-day. Put on 35 pounds on regular Depakote and on ER (took regular Depakote 9 years prior). But WORTH IT- when phased off once, suffered seizure within days- when on either med, NO SEIZURES EVER! M 41 9 months
6/22/2006
 2  Daily "migraine" headaches Weight gain, hair loss I'm 5'6 and I weighed about 130 pounds when I started Depakote ER (500 mg/day). After being on it only a month I had gained 10 pounds. I was constantly hungry. I also have very thick hair and it started falling out in small clumps. I have headaches every day which my neurologist says are some kind of migraine and out of the 30 days I was on Depakote, I still had a headache for 25 of them. I am switching to Topamax, hope it works! F 20 30 days
6/22/2006
 5  seizures some tiredness and hair loss Excellent and I have not had a seizure in 6 years F 50 5 years
5/26/2006
 3  bipolar rash, weight gain, trouble sleeping i dont really like it i am tired alot and i dont sleep well at night i have gained some weight taking it and i am constantly itching all over. F 15 4 months
5/21/2006
 5  Bipolar II No Negatives. Take with low dose Prozac. Awesome reults. Thank you God. F 29 5 years
5/15/2006
 2  Genetic Seizure Disorder Mom's point of view for daughter on this medication.Extreme increase in attitude.Drama queen.Takes at night and falls asleep almost immedietly.A/B student now flunking.Was taking Depakote twice a day.Is somewhat better with Dep ER.Appetite increase. EEG now shows normal.Liver normal.More hyperactivity.Angry.Can't comprehend some things and can't stay focused. Mom doesn't like and is looking for other options.This is the 4th medication in 8 months.So far is the best but still not happy with it. F 8 4 months
4/7/2006
 2  Bipolar 1 Migraines, hair loss, large weight gain 120lb. In 2.5 years, tremors in the arms and hands, indigestion, reduced memory This medication worked wonders, but due to the side effects it was not the medication for me. I gained 120 pounds in 2.5 years I went from 140 to 260 pounds. It gave massive migraines that rendered me useless. I do recommend this med but make sure you are willing to live with bad side effects M 26 2.5 years
3/25/2006
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 2  Bipolar II Hair loss, weight gain (15+ lbs), hand tremors, "flat-line" affect (i.e. no true depression but lack of caring about much of anything; no joy) F 51 5 months
3/11/2006
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 3  Bipolar Hair loss, weight gain (20 lbs in 5 months), serious tremors. I am on 2000 mg. of Depakote for mania and notice that not many people are on that high of an amount. It does work for mania but sometimes (especially lately) I feel very depressed. It worked at a lower does but my doc thinks I might get manic again M 43 2 days
2/20/2006
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 1  depression and mood swings severe headache, tremor, asthenia, nausea, trouble thinking I could not tolerate depakote at all when added to the other medications I was taking (cymbalta, topamax, lamictal). I don't recommend it be added to a complicated pharmaceutical regimen. F 51 1 months
2/10/2006
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 3  mood stabilizer Loss of appetite, exhaustion, lethargy, disturbed sleep, extreme dry mouth Haven't heard anything about this but I have a constant, lingering, bad taste in my mouth ALL THE TIME. It makes a lot of food and drinks taste AWFUL, so I have little desire to eat. Lost 5 pounds in a week. Also, have constant dry mouth, can't get enough water even though i drink constantly. F 27 30 days
1/27/2006
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 5  Basilar Migraines + Bipolar 2 None. Since I've been on this, I haven't had one migraine and I get depressed a few times a year for a day instead of every month for a week or two. It's also helped to make my ADHD more mild - so I haven't taken my adderall more than once a week for a few months. F 23 1.7 years
1/6/2006
 5  Simple Partial Seizures. Anxiety Side effects minimal with the extended release version. This AED is the best I have ever taken. No cognitive impairment as with Lamictal, Dilantin, Tegretol, etc... This drug works in so many different ways to calm the overactive mind it is truly unique and unbelievable. I will never change, regardless of what happens. My liver has always been fine on it. Side effects are definitely less taking 250mg 3x a day. Although it is extended release I notice it most effective with at least twice daily dosing. Not only controls seizures for me but it OBLITERATES the anxiety accompanying the seizure disorder. M 33 7 years
12/31/2005

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