ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 3  Depression Helped, but not worth the side effects of weight gain, acne, groggy all the time, zero libido, no motivation, body aches and pains. My prescribing Dr added Zyprexa to help with a severe withdrawal and agitation incident I had 5 months ago when my pharmacy slipped me generic Tofranil PM instead of the brand name. Zyprexa helped calm the side effects of withdrawal, which were pretty severe. I began experiencing relief within 36 hours. Since that incident, I've decided to try a natural approach to treating depression because I'm fed up with the horrible side effects that medication can cause. I've been able to wean off all other medications with the help of a Naturopathic Physician, but getting off of Zyprexa is proving to be a battle. I experience severe withdrawal symptoms if my dose is lowered too quickly or too much, so I have to abide by a 10% discontinuation schedule (10% reduction of dose every 2 weeks). I gained 30 lbs on this medication, it is messing around with my hormones, I have pretty bad acne, am groggy all the time, have zero libido, no motivation to do things, and now I'm experiencing a lot of body aches and pains. I am thankful for the help Zyprexa provided, but I'm looking forward to being free from this medication. F 32 5 months
2.5 1X day
11/26/2010
 3  Bipolar I Weight gain, hypersomnelence (sleeping 11-12 hours every night), sluggishness I was a champion of Zyprexa when first on this website about 6 months ago: it calmed me, helped me sleep. But as time wore on, I began to find its considerable side effects intolerable. My partner twice mentioned my weight gain and finally called me unattractive and questioned why I would be so commited to a drug that makes me fat and is leading me to diabetes. My doctor diagnosed me as being pre-diabetic (I am 32 years old). I was a person who was always a healthy weight and, with Depakote and later Zyprexa, I gained 70 lbs in a year. Most recently, I finally insisted to my doctor that I go on Lithium and come off the Zyprexa. To my surprise, he told me, "The more I am in practice, the more I am turning back to prescribing Lithium to my bipolar patients." Wish he'd told me that 70 lbs ago! Don't try this drug without trying Lithium first. F 32 12 months
5-10 mgs 1X day
1/12/2011
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 2  bi polar this shit hypes me up- not what i wanted for my insomnia doctor had me on seroquel- which was great for insomnia, but come time to get the prescription my insurance would not cover it, so then he puts me on a sample of zyprexa. it kept me awake for like 2 days. when the high wore off i slept and it was deep sleep but basicly this feels like a party drug to me, when i'm on it im thinking about vodka. 400mg of Seroquel just knocks me out so I'm not craving it except at bedtime, unlike Zyprexa, which i binge them. this is definately not the drug i want to be put on, because i'll just binge it- it feels like a grimy drug you buy off the street and i can't believe it knocks ppl out because it makes me feel speedy. M 32 5 days
7/12/2007
 1  bipolar i took this medicine 7 years ago i gained 60 pounds in 8 months and i didn't even take the medicine everyday my docotor has been scared to give me this medicine ever since the medicine does nothing to control my symptoms its just makes me really tired and feel unhealthy FAT F 32 6 years
5/6/2007
 1  Withdrawal problems Breathing problems - probably kills me (dysautonomia?) Zyprexa is just deadly drug - one should try to discontinue it before its TOO LATE (but withdrawal can kill too). M 32 2 years
10 1X day
6/30/2013
 1  psychosis Extreem extreem uncontrolable fatigue-sleeping at least 14 hours per day, extreem weight gain-20 kilo's (40lbs) in 2 months-it was all retained fluids.Complete loss of concentration/ decrease mental skills. Antipschotic drugs are an extremely dangerous medium. They can cause severe brain damage. Better drugs should be manufactured. I am still recouperating from rispardol and have a permanent decrease in mental capacities and a dangerous hormonal imbalance. In my opinion, psychiatrists are among the biggest criminals;being liscenced to prescribe such toxins to people. I think everybody afflicted with problems of this nature has to do their own research and figure out what really works for them;hopefully some new drugs are on the way. Keep up with farmaceutical studies... F 32
15mg 1X day
7/3/2010
 1  Schizoaffective Disorder Absolute destruction of sexual capability to the point my wife had an affair on me just to get some satisfaction. Supreme sedation. Gained 95 pounds in one month. Diabetes Type II. Stay as far away from this drug as you can. Sure, it does stop psychosis quickly, but all the side effects in the world are not worth it. My wife is gorgeous, I am so attracted to her, and because of this drug our marriage is in ruins. I took myself off this drug against doctor's orders and now I can perform again. It is most definitely Zyprexa that did it. Also, who wants to gain almost 100 pounds? I'm sure that didn't help my particular situation. M 32 4 years
40Mg 1X day
2/6/2010
 1  Severe stress! Whilst I was on it I was in a zombie like state and suffered problems with my libido (couldn't climax and was losing my erection.) I took 2.5mg for 2 days and 5mg for 8 days. Stopped for the aforementioned reasons. 8days after stopping 'ZYP' the muscle between my thumb&index finger (Right hand) twitched for 30consecutive days, as many as 200+ times per day. 9days after stopping 'ZYP' I had 1week of horrendous symptoms - night&day sweats (sweated excessively for 7days, lost my appetite for 3weeks, Nausea, grinding teeth, frequent night wakings, agitation, restlessness, freezing cold extremities, body shaking, constantly fluctuating between feeling hot&cold, sweaty palms, increased salivation & a feeling of being very unwell - I thought I was dying! 3 & a half weeks after stopping 'ZYP' I developed frequent night wakings which I now have every single night (almost 6weeks now) and GP had to put me on 'Amitriptyline' as I was severly sleep deprived via my disturbed sleep - never had frequent night wakings in my life before! Also 3 & a half weeks after I stopped taking 'ZYP' I developed twitches, tremoring & jerking of my 4fingers in M 32 10 days
9/22/2006
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 1  Severe Stress! continuation of the post I posted below ........ .... jerking of my 4fingers in my left hand. Just over 1month of stopping 'ZYP' my hands & forearms started shaking whilst doing things like holding cutlery or holding the phone. 2weeks after stopping 'ZYP' I had 6weeks of bilateral hip&shoulder blade pain, neck pain&pain in my chin but that has cleared up now. I think the possibilities are I've drug induced parkinsonism or tardive dyskinesia which would make sense as I took a 'dopamine antagonist'. My GP disagrees with my theories. GP's can be wrong though! If you want to email me please feel free! M 32 10 days
9/22/2006
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 1  depression I was prescribed zyprexa to fight depression, but side-effects (weight-gain, memory loss, drowsyness, dizzyness) depressed me even more. I am a university student and I have lots of difficulties in studying and being awake owing to that crap called zyprexa. Stop taking it if side effects outbalance benefits, even against your doctor's advice M 32 5 years
5/7/2006
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 1  Bipolar Unability to think. Breathing problems. Diarrhea. Diabetes. One should never volutarily start to use Zyprexa. Too low doses (> 5mg or something) can kill you (receptors open and close all the time (receptor bindings are not saturated enough) and damage brainstem, spinal cord or something else). Both too high doses (side-effects) and too low doses are FATAL. DEAD-END: People get side-effects and die or people reduce dosage and die. If you are put on zyprexa you probably should start planning your life so that you won't live very long (5-10 years) anymore. M 32 2 years
5 MG 1X day
12/3/2012
 1  Stressful life events Initially none. Started due to dishonest doctors diagnosing me to be in psychosis. After reducing dosage to 5mg/day there is pale skin. Now after 3 years of use I have breathing problems and maybe some kind of heart problems. I think I'm slowly dying to Zyprexa. Some kind of pseudoparkinsonism (hard to initiate movements) and heart failure symptoms related breathing. I think I will try to discontinue although I'm probably suicidal [need to use statins - there is at least atherosclerosis and other problems]. http://nonpsychiatry.wordpress.com/ Films: V for Vendetta, Matrix, CCHR: Psychiatry Industry of Death, Batman 3 (breathing) etc. M 32 3 years
20 1X day
2/8/2013
 5  schizoaffective disorder Increased appetite, rapid weight gain, drooling, nightmares The side effects are a small price to pay for the benefits. My fiance suffers from schizoaffective disorder, which is the worst of both worlds: schizophrenia and manic phase of bipolar. He doesn't want to take meds long term, so I keep Zyprexa on hand because thus far it is the ONLY drug that takes him out of a manic schizophrenic attack and keeps him out of the hospital. As a pharmacologist myself, I feel that Zyprexa, a very powerful and effective drug, should be used only as a prophylaxis for a short time and then weaning off, but not for long-term usage. Zyprexa is truly a miracle drug, and I laud Eli Lilly for manufacturing it! M 31 5 days
30 1X day
1/5/2015
Email
 5  Schizophrenia Extensive weight gain, loss of strength and tone, sleeping half the day away, not able to sleep until 2 or 3 am I am not diabetic despite taking for 16 years...and Both parents diabetic! Noticed alot of people don't like this drug for no reason. Some even say their diabetic after a few short years which is not my experience. M 31 10 years
15mg pd
2/8/2017
Email
 5  Bipolar 1 Weight gain only Zyprexa saved my life. I was experiencing psychotic symptoms and Manic depressive swings. I take 20 mg at night, and it has calmed me and brought me back down to earth many times. I have gained quite a lot of weight, but the pros well outweigh the cons. F 31 6 years
20 mg 1X day
7/30/2020
 4  Psychotic Bipolar On 10mg. Sleep well on drug. Difficult getting going in morning, glad I'm not rushed. Partial memory loss. Want to study at uni next year so hope it is not going to be affected. A little sad, but this may be long term depression. Antipsychotics as a general rule suck big time. (I should know I've been on risperdal, seroquel, camcolit, serenace and fluanxyl) Relative to the rest, zyprexa is not that bad. I don't feel weird, or become the screaming aggro man, or look like the 'plank' man, or have too bad dyskinesia (that's when I shake like elvis out of control), or sleep 'till the cows come home. I think with an understanding employer I could find work. A little concerned about diabetes considering my bro has it without zyprexa and my grandpa died of it. Watch this space. M 31 3 months
10/17/2007
 4  Treatment Resistant Depression dry mouth, stiff muscles. I take 5mg with moclobemide (RMAOI) at night. I feel much less depressed, to be more specific - I'm no longer constantly ruminating over everything negative, my mind is lighter. I feel more assertive and have more 'oomph'. I generally feel better, I just hope it lasts as its very early days, and most things tend to poop out on me (and thats not depressive thinking, its based on experience!). I felt it working within the first few days. Also my voice is sounding stronger, strange thing but depression/anxiety makes my voice sound a bit strangled. F 31 11 days
12/17/2007
 3  Cops arrested placed hospital Inomnia? I think this medication 10 mg is a great stress reduceer. I started sleeping later then all of a sudden Insomnia hit me so I stupidly started to take seroquel 50mg <------- makes you a stonned zombie now I have insomnia ever after taking seroquel I've tried different sleep meds but they are short lived my advice don't take any of this crap if possiable especially if someone brought you to the mental health floor and they were dressed in blue. I had no choice I had to take it like a big medicated wuss otherwise they would ship me off to a really metal ward. M 31
9/17/2006

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