TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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 Type: Rx Drug

  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  breast cancer After my mastectomy, I did AC-T chemotherapy. 4 treatments of AC, then 4 of TAXOL. Treatments were intraveinous, once every two weeks. With the TAXOL, I got severe pains in the legs two days after the treatment. I took one ARCOXIA pill - and was pain free for the next 2 weeks. This happened for all four treatments. Hope this works for you too !! M 63 60 days
1X AN
10/30/2010
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 4  Breast cancer After 4 3-weekly doses of A/C (few side effects, mainly tired and complete hair loss), I started on weekly Taxol, 12 doses, 3 to go. Apart from tiredness, I had no problems until the 6th dose. Since then I had haemoglobin loss (had to have a blood transfusion) and have had red, swollen, scaly, intolerably itchy hands and wrists, and one badly swollen, red, painful foot and ankle. I had a couple of minor infections. I've also lost all sense of taste except for the metallic taste in my mouth which no amount of mints can cure! Reading other people's experiences, I realise that I've had it pretty easy. Cortisone cream and vaseline on my hands is helping a bit. Antibiotics cured the infections. Only three more weeks of Taxol to go (then radiology). Don't know if it's 'cured' me, but I trust my oncologist, and he reckons I'm doing very well, and hair, taste buds, and decent hands and feet should soon come back. F 68 9 weeks
1X W
10/13/2010
 4  Stge 3 G3 Triple negative breast CA Joint pain in legs, arms & lower back, numb fingers and feet. I received this treatment after 8 weeks of AC which was a non-stop nausea ride & lost all my hair. I would take Taxol over that anyday. No motion sickness or nausea. I've worked full-time (office) while getting both treatments & I'm alive. Yay! F 37 8 weeks
1X W
9/29/2010
 3  stage 2 breast cancer Experienced the classic symptoms during treatment. However, after treatment, peripheral neuropathy in my feet. Numbness in all toes. Tingling in all toes. All toenails and fingernails are falling off and have fungus infections. Balance and walking are severely affected. Help! What is the treatment for the fungus???? F 64 56 days
30mg 1X W
7/7/2010
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 3  breast cancer I took Taxol weekly for 12 weeks, along with Herceptin (I just finished my year of Herceptin). I've been off Taxol since September 2010 and while my counts and general health were good throughout, I had some severe neuropathy and balance issues. I tried Lyrica, gabapemtin, glutamine and lots of naturopathic remedies. I still have intermittent intense discomfort in my feet, muscle weakness, balance issues. I am an active 55 year old and it has definitely diminished my level of activity. I still feel I did the right thing, despite the neuropathy. I had a recurrence (actually a totally new breast cancer in the other breast). Was HER2 neu positive, too, so feel I have to deal with the side effects as I want to stay healthy!!! F 55 12 weeks
100 mg 1X W
5/31/2010
 3  Stage 2b Breast Cancer Four A/C treatments with minimal side effects (fatigue & hair loss). Thought Taxol would be a breeze but I was wrong. The bone & muscle pain (mostly from the waist down)started 3 days after my first Taxol treatment and was so severe I took Darvocet that was leftover from my surgery. Pain lasted 5-6 days. Second Taxol the pain started 2 days after and lasted 9 days. Third Taxol the pain started the next day and lasted the full 2 weeks until my last Taxol which was 2-1/2 weeks ago. Pain is still incredibly intense. Initially the pain was more in my hips, legs and feet. Now it's also in my shoulders, arms & hands. I also have neuropathy and darkened nail beds but I can deal with that. I had 4 A/C treatments with very little side effects. The Taxol has definitely been much harsher on my body. I have a very high pain tolerance and the bone and muscle pain is about a 9. I've been on Vicodin since the 2nd Taxol and have had to increase the dosage with each treatment. The pain came on earlier and lasted longer with each Taxol treatment. I called my oncologist 2 weeks after my final Taxol and he increased my Vicodin dosage and also prescribed a muscle relaxer. Not sure how long this will last but I'm hoping it won't be much longer. I had the option to go with the 12x weekly Taxol dosage but thought since the A/C was so easy that I'd do the 4x every other week. Not sure if it would've made a difference. F 47 8 weeks
2X M
5/26/2010
 1  Breast Cancer Severe leg,arm and wrist pain and weakness. Metallic taste in mouth. Fatigue,sleeplessness and dizziness. Trouble concentrating. HORRIBLE!!! Difficulty walking. Can't sleep due to pain yet so tired can't do anything else.Chills. F 59
2X M
5/22/2010
 1  breast cancer stage 2 grade 3 ducta 8 months after my last treatment I am still experiencing peripheral neuropathy in my feet, ankles , hands and wrists. My pain was 10 out of ten (agony). I have numbness in both of my feet that cause my mobility and balance issues. I have fallen an injuried myself because of the numbness in my feet. I wear protective shoes at all times to prevent injury if I step on something and to give my balance. There is not a time that I am without pain. I have tingling in my ankles at times of shooting pain. In the morning I my hands are curled up and in pain. I have not returned to work because my balance is so poor. The quality of my life has diminished. At 53 years of age I feel 90 years old. I have tried Lyrica , gabapatene, and amitriplyne as well as Vitamin B and glutamine. None have been able to relieve the pain and often have left me in a bit of a mental fog. I have always been physically active and have tried to continue to exercise by riding my stationary bicycle, walking,( with the worst gait possible)yoga, weight lifting rehab pilates on a reformer and just started dragon boat racing. Any exercise you can do sitting down . I have tried to golf 9 holes riding a cart however my ankles are so painful afterwards I con't know if it is worth it. My typing accuracy is dreadful since I can't feel the keys. Taxol might have saved my life from a recurrence of cancer but it also stole the quality of my life and livelihood. All I have been told is that it might get better over time. One can only hope. I have just recently been seen by a neurologist. When I told my oncologist after the first round of taxol that it was the worst pain I had ever experienced that he joking said that I had never experienced labor as if that would be more pain than I was experiening . I told HIM, HE never experienced labor either and not that type of pain now for 8 months.... I have tried everything I can do from drugs, diet, exercise, mediation etc...however I have no control when or if the periperal neuropathy and my mobility will F 53 4 times
4X O
5/20/2010
 4  Triple Negative Breast Cancer Some fatigue on days 3-5 post treatment. Some joint pain in shoulders. My hair thinned out significantly, although I didn't lose it completely. I ended up shaving it off anyway since my insurance paid for a wig. I just had my 9th treatment (3 more to go) and I have been getting headaches now for the past couple of weeks. Today's was the worst yet. Hoping they subside soon. I haven't had any major issues with Taxol. My chemo experience thus far has been better than I anticipated. I begin FEC in 3 weeks and I'm hoping it goes as smoothly as the Taxol has gone. F 35 12 weeks
1X W
4/15/2010
 2  Triple negative breast cancer Numbness/loss of sensation in fingers and toes; no sense of taste, so food seems disgusting; awful, bitter coating in throat; 3 days after treatment bone/muscle pain starts and lasts for 4-5 days. Worst in the hips, lower back, and knees, but also shoulder bone and ankles. I hobble around like a 90-year-old, just as many of the comments above mention! Did 4 rounds of A/C followed by 4 rounds of Taxol--the last round is later this week. My onc said that since I tolerated dose-dense A/C so well, Taxol would be a breeze. Well, it's different from A/C but I wouldn't call it a breeze. I sure hope that this was worthwhile, but I guess that only time can tell. F 49 2 months
2X M
3/15/2010
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 4  Stage IIIa BC, one side mastectomy Painful brittle, yellow nails; mild neuropathy in fingers, tired I took 12 weekly Taxol Tx after AC for 2 months every 2 weeks. Taxol was so much easier! Dexamethasone was giving me trouble (water retention and weight gain of ~12lb by the end of tx). I am now 1 month after tx and feeling really well. I was exercising throughout my treatment, walking 4-9 miles almost every day, swimming several times a week and working almost full time. I even went skiing in the Rockies while on Taxol! I believe that good physical condition before dx and continuous exercise during tx helped me to go through this difficult time. It was not exactly a walk in the park but close enough. I started radiation now, Arimidex and Clodronate and still run. F 59 12 weeks
1X W
3/13/2010
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 5  BC Stage3A Hair loss, nausea, neutropenia and anaemia. I continued working (office), but had to quit the gym, which I resumed 3 months after the last chemo and surgery. I had a giant tumor, which after Taxol reduced to 10.5 cm but had free margins. I'm currently finishing my rads and taking Armidex. Apart from the anaemia and neutropenia, which required some extra care the treatment went smoothly. 3 months after I still have a bit of neutropenia but my quality of life is OK, besides the doctor says I'm cancer free! F 48 6 months
1X O
2/5/2010
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 4  BC Triple Neg Stage 1 (1.8cm) Numbness in fingers and feet. Joint pain in shoulders. My treatments consisted of a lumpectomy, 4 rounds of Adriamycin/Cytoxan, 4 rounds of Taxol, and 33 radiation treatments. I experienced joint pain and numbness in feet/hands from the Taxol. Did chemo from April through July of 2008. Still experiencing shoulder pain and some numbness in my feet. Drinking Kangen Water (electrolyzed water) helped to keep me hydrated throughout treatments. Also - never threw up during chemo. This redhead barely got pink during radiation. I love my Kangen Water and feel it helped tremendously during my treatments. F 45 4 weeks
1/22/2010
 4  BC Stage 2A 04/16/09 was my last Taxol treatment. I am still experiencing joint pain, muscle weakness BUT, it is much better now than before. The joint pain/stiffness is worse of a morning. Once I take a shower, the warm water seems to allow me to be more moble. I haven't gained weight, actually I've lost more since treatments. I also took 33 treatments of Radiation after Taxol. I would like some feed back from other BC survivors who was dx with triple negative BC. My appetite is back to normal, I just get full quick, also experience alot of loose stools. I also notice problems with my memory. Not too back, but it's there. F 53 12 weeks
11/17/2009
 5  Stage IIA Breast Cancer After 4 treatments of AC, Taxol although isn't a walk in the park is easier. Side effects include bone aches days 3 - 5 usually starting in the afternoon. Fatigue. Bowel problems. Mucous in stool and stomach pain. No nausea. Nose bleeds. New side effect - rash on hands. Lost my hair during AC and seem to be losing more with the Taxol. Currently on 8th cycle of a 12 week low dose Taxol. Looking forward to having some energy again. F 51 12 weeks
10/26/2009
 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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 4  AC for stage 3c BC, reduce tumors Fatigue, incontinence, more hair loss, low BP, not too bad. Intermittant bone discomfort, AC reduced BC stage IIIc from 4 cm to 1 1/2 cm. Still not small enough for surgery. Will be 11 more weekly infusions as I seem to respond well to chemo. Am getting benedryl to reduce side effects. I can tough it out! AC was bad, yet I survived that. Am taking probiotics, antioxidents, calorie counting, metamucil, etc. Keep the body alkaline and healthy so the chemo can do its job. Nausea was associated with low blood sugar. Don't listen to horror stories, a positive attitude makes an alkaline body. I know its going to get worse but I have faith in my oncologist. She'll get me through it. F 73 5 days
8/21/2009
 5  metastic breast cancer F 50 3 weeks
8/8/2009
 5  Stg.4 OvarianCancerPrognosis 2 mos. Tired, weak.#10 pain @times in feet and legs.It has been 16yrs. this June and is difficult to remember everything about the treatments. But I have SUFFERED incredible pain since then. Every hair on my body was lost during treatment but came back.That was nothing compared to this last 16 yrs. I would take it again because it helped save my life. I have memory loss and difficulty concentrating. Just something else to work on. LOL. Thanks to my Dr for putting me on anti-depressants. That in itself helped so much. Knowing that I am mind, spirit and body I went to work on all three. I "raged against the dying of the light", that ol' cancer. I suffer daily but would have missed so very much. Peripheral neuropathy and shortly after I completed the Taxol and Cysplatin I was diagnosed with Fibromyalgia.Some folks think I'm lying about having Ovarian C.especially metastasis but I have the papers to prove it. First I had to decide whether I REALLY wanted to live. Then I started kicking butt My story is too long to tell now but I'm still amazed that the bark of the Yew tree helped save my life. After 3 rounds we did another CT scan and the mass of 3 tumors in my pelvic area the size of grapefruit were gone. Still had many small tumors "lining the wall of my abdominal region." They had to put me in intensive care to administer it every 21 days because it was so strong. I was diagnosed June 1, 1993. I'm still here.The staph in my port. almost took me out! Sometimes when it gets so bad you just gotta laugh..it helps. F 65 9 months
6/22/2009

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