ZESTORETIC Reviews (HYDROCHLOROTHIAZIDE; LISINOPRIL)

Average Rating: 2.8 (44 Ratings)

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 Type: Rx Drug

  

ZESTORETIC  (HYDROCHLOROTHIAZIDE; LISINOPRIL):  This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. This product is used when one drug is not controlling your blood pressure. Your doctor may direct you to take the individual medications first, and then switch you to this combination product. Do not continue taking the individual medications (lisinopril and/or hydrochlorothiazide) after you start this medication.   FDA Approval Date: 1989-07-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ZESTORETIC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZESTORETICCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  hypertension I started on 10mg; each time I reduced the dosage (to 5mg, then to 2.5mg) I experienced some depression, which abated after 3-4 days. There are no ongoing side effects I can attribute to Lisinopril. F 52 1.5 years
6/18/2007
 1  yes Cough, fatigue Persistant hacking, itching cough coupled with excess muccus and increased sencitivity to catching other viral infection.Also exhibited with Monopro. F 30 3 months
6/10/2007
 3   Light headed, dizziness, vision changes, muscle spasms in back of necks, sleepy all the time. I'm on 20 mg, along with dilacor. BP is normal, but because of the side effects, I need my doctor to adjust or change types. Too many side effects that stop my day to day functions. Dizziness, need to sit down, then I get sleepy and fall asleep. F 41 3 months
4/30/2007
 4  Hypertension None. Most side effects I read about on this site are over-hyped. People get caught up in "creating" side effects. I'm an RN and I rarely see any side effects, other than cough for this medication. Combination ACE Inhibitor/Thiazide diuretic works extremely well in controlling hypertension; the benefit is through the synergistic effect the two drugs have on the renin-angiotension-aldostersone mechanism. F 36 8 months
4/6/2007
 1  Hypertension Tiredness, confusion, forgetfulness, loss of motivation, irritating cough, unexplained urinary tract infection (first time in my life). All side effects (except uriniary tract infection which required antibiotics) ceased within a week. Doctor prescribed Co-Diovan as an alternative, but I noticed a listed side-effect for this drug was urinary tract infection! Went onto Natrilix SR (Indapamide) instead (1.5mg daily) - no unpleasant side effects so far ... I am feeling 100% better. Did reduce blood pressure, but the unpleasant side effects were not worth it. M 47 6 months
10/10/2006
 4  Hypertension none really- maybe slightly reduced sex drive but this is marginal. I am on low dosage- 2.5 mg since blood pressure was persistently high but not extreme e.g. 140/100- now around 130/80. Family history of hypertension was motivating reason for using this. M 33 3 years
6/28/2006
 4  high blood pressure Skin rash when in sun. Also, dry, hacking, very annoying cough. It worked wonderfully to lower my BP and I tried to take it as long as possible, but cough interfered with work, sleep, and got on everyone's nerves around me. I had to stop. F 41 4 weeks
6/25/2006
 3  high blood pressure Tolerated 5mg for 5 years with little side effects. Did notice a decrease in sex drive. Now on 10 mg and experience lighthead, metallic taste, pain in breastbone, dry mouth. Hopefully the larger dose side effects dissipate soon. I do remember some of these side effects when I started taking the 5 mg for awhile. The side effect that is irritating is the lower sex drive. It comes and goes. M 30 5 years
6/7/2006
 5  hypertonics none M 72 3 years
4/28/2005
 4  hypertension Cough, dizziness , and hypotension in the heat , plus rash. Because of the side effects I am looking for another drug. M 74 4 years
2/10/2005
 2  High Blood Pressure At first, dizziness, fatigue, vision changes, sensitivity to light. These symptoms did resolve, however recently I have started to have left leg pain, and numbness/tingling to my left hand, and arm at night.Did significantly reduce blood pressure from 164/132 to between 110/60- 120/80, just couldn't tolerate the side effects. My doctor just switched my medication to Hyzaar 50/12.5, so I hope that it will be the right medication for me. F 33 4 months
1/6/2005
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 3  high blood pressure light-headedness and fatigue but tolerable after continued use. Blood pressure fluctuates frequently from normal to borderline(especially when stressed). Otherwise, must work because my doctor has maintained me on 10mg daily for past 8 years. F 52 8 years
10/25/2004
 3  high blood pressure light-headedness and fatigue but tolerable after continued use. Blood pressure fluctuates frequently from normal to borderline(especially when stressed). Otherwise, must work because my doctor has maintained me on 10mg daily for past 8 years. Will occassionally experience dry nagging cough at night. F 52 8 years
10/25/2004
 4  HIGH BLOOD PRESSURE WELL, MY BLOOD PRESSURE STAYS DOWN...BUT....UNFORTUNATELY, SO DOES MY PENIS. BEEN ON IT 5 YEARS. SAME PROBLEM ALL THIS TIME, AND I'M IN VERY GOOD HEALTH. M 71 5 years
8/12/2004
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 4  Preventative medicine Just a slight dry cough at first and tiredness on 10 mg. Reduced to 5 mg and no problems. Put on Zestril for preventative measure - slightly raised BP. I now feel more relaxed in everyday life, have had no problems with erectional dysfunction. Have slight hair loss but don't know whether I can pinpoint this to Lisinopril or not. All in all so far so good. M 54 2 years
3/6/2004
 4  Hypertension I got a cold 20 months ago and have had a sore throat and phlegm ever since. I have only just realised that this could be caused by the zestoretic. Blood pressure is 166/98 and is regularly over 90 although can drop to 75. Otherwise has served me well. M 53 15 years
8/22/2003
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 1  high blood pressure I developed a persistant dry cough which became very irritating. Worked fine on lowering the blood pressure but I could not tolerate the cough. I switched to diovan, the cough stopped and my blood pressure is fine. F 75 2 months
2/1/2003
 3  control of high blood pressure [Lisinopril] In the 4th month I developed a daily and persistent itchy/dry throat combined with a dry cough. Disrupted nightly sleep and very annoying during daytime. Dr. switched my medication to Cozaar. 20mg daily intake of Lisinopril controlled blood pressure quite well. Did not like side effect. M 66 4 months
12/3/2002
 5  high blood pressure The best side effect I've experenced is a normal blood pressure reading and I enjoy a healthier lifestyle. It has also helped me keep off the added pounds of water weight. Now I drink as much water as possible but all is does is keep my kidney working. F 46 26 years
7/29/2002
 1  high blood pressure Continuous Dry cough, diminished sex drive--both physically and pschologically, drowsiness when taken during the day but very frequent urination when taken at night. F 44 15 days
7/15/2002

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