LARIAM Reviews (MEFLOQUINE HYDROCHLORIDE)

Average Rating: 1.2 (149 Ratings)

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 Type: Rx Drug

  

LARIAM  (MEFLOQUINE HYDROCHLORIDE):  Treatment of mild to moderate acute malaria or for prophylaxis of malaria    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LARIAMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  visit to zimbabwe vomiting, diarrhea my lips and nails went blue, confused. taken 15 years ago. i would not want to contract malaria so it is important to take an antimalaria drug, just don't take Lariam! I thought it was banned but seems like it is still being prescribed. F 35 3 days
1X day
6/8/2012
Email
 1  Trip to Kenya I am on it now. I can't sleep. I can't stay warm, then I am cold. Every mood is exaggerated. I don't become annoyed, I go straight to a state of blinding fury. I don't get sad, I become horribly depressed. I was not told not to drive and three days after getting on this stuff, I got in a race and went over 80 on a winding road and was in horrible accident (no one has seen anyone walk away from one this bad, not even EMS). I thought my boyfriends mother was going to attack me (delusions), and I had a panic attack in the car after the crash. I can't think clearly. It's like thinking through wax paper. Everything is there, but I can't get it. I don't understand it unless I really concentrate on tasks and concepts I found simple a month ago. When I try to remember parts of the crash, it is like I am seeing it third person. It is as if I am watching a movie, not remembering it. I see the scene from an aerial view, not from the backboard. I am paranoid and when people try to touch me I scream and cringe. Although I suffered no serious head injuries, I can not remember most of the night of the crash. I blacked out. It is the most awful thing I have ever experienced. F 18 1 weeks
Unknown
6/4/2012
Email
 1  malaria major depression, anxiety disorder, sleep problems, teeth grinding (bruxism), chronic fatigue, mood swings, personality changes, aggression, suicidal ideation, brain fog, diminished capacity, impulse control problems, anger control problems, MY ARMY UNIT at FORT BRAGG NC was ordered to take LARIAM (mefloquine) when we were on alert to try to rescue the US hostages in Iran in Nov. 1979. No one told us we were being used as guinea pigs for an experimental drug without our knowledge or consent. No one ever asked us if we had any side effects after Within a few days, paranoia and anxiety started, and within a few weeks, I had full-blown cycling between major depression and violent mood swings, and I have NEVER been the same since. But because I didn't know what happened to me, I went 20 years undiagnosed and untreated, and I have now been on max dose anti-depressants since 2000. Symptoms get worse with age, and I am no longer able to work. When I finally knew from research it was Lariam, in 2008 I applied for VA disability, but after 4 YEARS the VA & BVA STILL will not give me an answer!!! M 54 1 days
megadose 1X day
4/28/2012
Email
 1  Trip to Mozambique This drug will take you to hell, and if you're lucky, back. 2 years on and still suffer panic attacks with weekly psychotherapy sessions. Traumatic experience. You'd rather be dead. F 30 4 weeks
250mg
3/11/2012
 1  Peace Corps Service in West Africa insomnia, depression, loss of appetite, extremely emotional, drug-induced hepatitis I was medically evacuated from my country of service after developing (very rapid) liver complications. The doctors did not know what was causing my liver complications, and they switched me to Malarone early on in the event that the problem was Mefloquine. It, in fact, was directly related to the Mefloquine. I knew that I was not myself while taking it, but after being off of it for about 4 weeks, I woke up one morning with my personality back. My liver functions tested normally after 3 months of being off of Mefloquine. I am very fortunate in that. Long-term effects are still to be determined. F 25 2 months
250 1X W
2/25/2012
Email
 1  trip to africa anxiety,depression,hot flushes,twinges in spine,head aches,suicidal thoughts,extremely voilent and death realted dreams,sickness,panic attacks,paranoia i ignored the warnings my friends had given me regarding the medication.i cant actually think straight right now and feel completely out of control due to these pills.dreadful dreadful experience.comes in waves.hope it will subside.going to the doctors to change medication! F 31 2 weeks
250mg 1X W
2/19/2012
 1  Trip to the Philippines Paranoia, anxiety, insomnia, loss of appetite, hot flushes, nausea and vomiting, depression, suicidal thoughts F 32 1 days
1 Tablet
2/15/2012
Email
 1  Trip to South Africa Panic attack, anxiety, nightmares, constant mood swings. This pill is a real danger, reading here about patient experiences and mine, I can not believe that doctors don't advise you about all the side effects, my girlfriend took malarone and was perfectly fine, me still suffering of nightmares and anxiety....I hope it desappear in a couple of weeks. M 34 5 weeks
250 MG 1X W
2/9/2012
Email
 1  trip to india Confusion, depression, sadness, scary dreams, numbness, fuzzy brain, suicide After taking only one pill, I noticed a reoccurance of depression symptoms, which I had not seen for over 5 years. This pill made me feel sad for no reason, emotional, and numb. I can;t believe my doc didnt ask me if I had any prior depressive episodes. 4 days later I still feel depressed. F 30 1 weeks
1X W
12/12/2011
 1  Malaria Prevention on trip to India Insomnia, paranoia, graduating into hallucinations and extreme psychotic episode lasting approx 3 months I CANT BELIEVE GPs ARE STILL PRESCRIBING THIS DRUG in 2011..After what happened to me over a decade ago on taking a course of this drug (and to many other people by all accounts - ask Paul Merton) I would say that it should be banned. Really scary that they still think it works. I was flown home on an emergency flight after risking my life on a trip with friends to India and Nepal due to a Lariam-induced psychosis, extremely frightening for my friends and dangerous for me. On the 'come down' back in a psychiatric ward in the UK (yes the effects were that deep, severe and prolonged..) I felt suicidally depressed for months and could still hear voices and thought that people were imposters out to kill me..all totally crazy stuff, I have never experienced such symptoms before, or, thankfully, since. What a damaging poison. F 36 3 months
30mg 1X day
12/3/2011
 1  Short term vacation in Zanzibar Severe insomnia, panic attacks, discomfort, slight paranoia, severe vomiting after alcohol intake. Still going on 2 months after the last pill, seems to get worse. My boyfriend was recommended Lariam by his Austrian doctor. He didn't feel any side effects but 2 months after the last pill, I still feel horrible, cannot get sleep, am subject panic attacks and paranoia. I wish I had never taken this, it ruins my life at the moment. F 25 4 weeks
1X W
10/1/2011
Email
 1  malaria Prevention 1994-1995 ....Following day after first dose I felt very I'll and stressed, not knowing what was wrong with me... I couldn't relax... and this feeling has sort of stayed with me. Virtually continuous use for 10 months. Continued suffering from fatigue, ANXIETY, disorientation, dizzyness, lack of concentration, headaches always the day after taking each pill ( I called it my Lariam Headache) , alternating between hot and cold within minutes, depression ( treated with seroxat causing more problems and Very Vivid dreams/nightmares) hospitalised in Abidjan for 3 days and all basic tests for illness proved negative. I have never got back to the feelings of peace and relaxation that I used to take for granted before I took this devastating poison. On subsequent much shorter visits to Africa, I used Malarone, which did not appear to have any significant side effects !!! DO NOT TAKE LARIAM !!! M 58 10 months
1X W
7/23/2011
 1  prevent malaria on holiday to India nausea, stomache ache, general feeling of ill health i wouldn't recommend it. Side effects came on very quickly. I've decided to go back to using the two tablets I had before when I went as I feel so ill. I thought it would be good only having one tablet per week as the other type give me stomach problems too but not as bad I've found F 56 1 days
1X W
3/2/2011
 1  Malaria I experienced swelling of feet, nausea, deathly frightening nightmares, suicide, paranoia, vomiting, diarrhea (not sure if this was from water though), pain in stomach, blood was really hot, losing my mind, sadness, crying for no reason, recollection of past and possibly past life, one patch of hair loss, jittery nerves, numbing and shaking hands and feet, and difficulty of breathing. I am happy I understand that these were side effects and not something I contracted out there. I do not recommend this drug to anybody. M 36 7 weeks
1X W
2/21/2011
Email
 1  Malaria prevention Anxiety attacks I have stopped taking it but the anxiety continues F 64 6 weeks
250 mg 1X day
2/12/2011
 1  Nigeria Insomnia, twitching, restless legs, loss of concentration, anxiety, psychosis, Depression, suicide attempt Took this for about one year starting at age 19. Not only did it not work (I contracted malaria while in Nigeria) but I also experienced the listed side effects for several years. F 35 1 years
Standard 1X W
2/3/2011
 1  Malaria Horrible. You wish you were dead instead. M 34 3 weeks
2X W
2/1/2011
 1  prevention of malaria nausea, vomiting, dizziness, low mood, heartburn, light headed I took 1 tablet last night and the side effects kicked in right away. I'm already on anti depressants and have a history of anxiety and major depression. My doctor did NOT warn me about the risks associated with Lariam at all. You'd think that with my history, he would be very cautious about prescribing this drug for me. It's clear after reading this page that my doctor along with many others know NOTHING about the risks. All of today I feel like I am having brain shivers.. as if my brain is struggling to keep up with my body and it's just rattling inside my head. I only ever feel this when I suffer withdrawal symptoms from missing a dose of an anti depressant. I did NOT miss any dose so I know it's the Lariam. Since last night I feel as if something is caught in my throat. It hurts to swallow when I eat because it feels as if my throat passage is narrower. I have severe heartburn. Taking a zantac did not ease the discomfort at all. My head just hurts. I feel dizzy. I had to go home half an hour into work this morning because I couldn't cope. I vomited when I got home. Went back to my doctor and he gave me Stemetil to help with the nausea. Even that isn't helping!!!!! I still feel terrible. My head hurts so much and I've been crying all afternoon. I don't know what to do. I've been poisoned. I am so angry that this drug is on the market. How dare they do this to people. F 22 1 days
250mg 1X W
12/15/2010
Email
 1  Holiday to South Africa ( Safari) Dizzy, fever, shaking, halucinations, flu like symptoms, extreme tiredness, stomach ache, headache, depression, crying unexpectedly, paranoia, panic attacks, high blood pressure reading, blurred vision, "foggy" head, loss of memory - hideous side effects. I had taken anti maleria tablets before but not this one. Was given it by GP nurses on the basis that "once a week dose is more convenient than daily" - it's not worth the risk! Take the daily one. Malerone works just as well but without the psychological side effects. Not saying there are no side effects with Malerone, but they are not as bad by a long way. One month after taking, I still feel unwell and hope it will eventually remove itself from my body. The GPs just try to give you Valium or similar to control the panic attacks (which I did not take as I am not keen to increase the chemical imbalance any further) but I am improving gradually. I went from a perfectly sane and controlled individual to a jibbering wreck and in my view, this drug should be taken off the market. The more people who publish their experiences the better so that others dont have their holiday ruined the way I did! F 47 2 weeks
1X W
12/15/2010
 1  6 month trip across Africa nightmares, anxiety, paranoia, took Larium in 1993, side effects immediate and I stopped taking it whilst away as couldnt stand it anymore. It has ruined my life, still continue to deal with cycles of depression and anxiety. Let me stress taking this drug changed me, I had absolutely no mental illness prior to my trip and was an outgoing personality. Returned to the UK from African trip to a media outburst from people who had reactions to this, however obviously nothing has changed as its still available. F 39 2 months
1X day
12/1/2010

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