INDOMETHACIN Reviews (INDOMETHACIN)

Average Rating: 3.0 (317 Ratings)

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 ANTIARTHRITICS

 Type: Rx Drug

  

INDOMETHACIN  (INDOMETHACIN):  Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling and pain. If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.   FDA Approval Date: 1984-08-06 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on INDOMETHACIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR INDOMETHACINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Undiff Spondyloarthropathy For the first 1 and 1/2 to 2 weeks I experienced fatigue (which is why you take it at night), mild stomach upset, and some blurred vision for a few hours after taking it (usually took it around 7pm after dinner.) These side effects subsided around the 2 week mark. I have to take Mylanta first or else I get stomach pain (from what I have read you want to protect your stomach and GI tract as much as possible when taking indomethacin.) I suffered from this rheumatological condition for around 2 years before finding his medication. My symptoms went from very transient sacroiliac joint pain, costocondritis, and profound fatigue, to constant sacroiliac pain and intense night pain in lumbar and, later, my thoracic spine accompanied by a kind of constant lower basline of fatigue (if you can call it that.) At least 2 days per week I would get bouts of intense fatigue probably from the inflammation in my body. Which is why I was a bit worried about the fatigue that indocin caused for the first few doses but now that has gone, and, more importantly, I haven't had any fatigue due to my illness since I began the medication. It is certainly a strong med and it seems like the kind of thing that should only be rx'd if needed but, damn, is it effective! 800mg of Ibuprofen or 750mg of Naproxen would only take away about 10% of my pain. I even took muscle relaxers and tried a few pain killers and nothing worked like this stuff! I take indomethacin daily, one 75mg SR(slow release)dose after dinner at around 7pm. It relieves 94% of my pain. I can walk, sit, and lay down without being in pain or anticipating how painful it will be to move. And, oh yeah, I can sleep again. I get a full night's worth of restful sleep. As long as I take mylanta 10 minutes before, the only side effect that I have now is fantastic, amazing relief!!! The best part is that it is an NSAID and helps thwart inflammation rather than simply M 30 2 months
75mg SR 1X day
12/18/2010
 4  for reactive arthritis helps me sleep, my stomach gets upset if i don't take it with enough food, i've started prednisolone 30 mg, so i guess indomethacin is a sort of a cover up for the insomnia that i get from prednisolone....both medicines work great but its too late now since i've developed a deformity in my right knee due to arthritis...also i cannot bend down to pick something up, but otherwise it really helps me relax and feel normal all of this started in 2004, the drug is great, its just that i haven't been diagnosed right by my doctor, i wasn't diagnosed in time M 19 2 months
25 mg 2X day
1/13/2012
 4  Hip Injury/Arthritis Inconsistent but SEVERE dizziness/"out of it" sensation, diarrhea, anxiety as a direct result of aforementioned side effects. (50 mg 2x/day) The benefits still outweigh the risks. Cannot take narcotics prior to hip surgery, but this ended up actually taking away more of the pain thank Tylenol #3. Difficult to function at work if taken with too few calories (should say "take with a substantial meal") and still refuse to drive after taking it due to the inconsistency of the side effects. No tolerance is built up, so it sneaks up on me sometimes! F 29 2 months
5/29/2009
 3  Trapped nerve in shoulder blade I take one tablet before bed time as they make me very drowsy and to aid a pain free sleep.I wake in the morning feeling on a slight high with a fuzzy head and as though I am not quite there. This feeling wears off after a couple of hours but so does the pain killing ability. I also suffer from a very bad lower back,often having ligaments out of place and disc movement. Indomethacin help me cope with the pain at night for these pains too as it helps me sleep. F 42 2 months
8/26/2008
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 2  Migraines I always take this with food. I was previously (years ago) on this @ 25mg, 2x daily. Worked well. Now I'm on ER, @ 75mg, 2x daily. Not a pleasant experience. My stomach is reacting badly-constant churning, always bubbly, nausea, pain. I think I have to stop this medication; the side effects are too harsh. I was hopeful but it's another fail. F 44 2 months
75 2X day
4/16/2018
 5  Gout After your body adjusts it's a miracle for getting over a Gout attack. If you have gout don't look anywhere else. My doc put me on it for the first three months of allopurinol. Best 3 months of my life. No gout no inflamación. M 42 3 months
50 mg
3/20/2014
 4  Trigeminal neuralgia, poss CH or PH Dizzyness and bad stomach pains / indigestion when first started but was on "normal" release pills of 25mg three times daily upto 75mg three times daily. GP switched me to 75mg slow release tablets three times a day and prescribed 30mg per day of Lansoprazole to protect my stomach. When I have missed Indo doses got awful rebound headaches, also recently started to suffer bad lower body and back joint pain, not sure if this is related. Prescribed as a "theraputic" course by my consultant as part of investigative treatment for CH (cluster headache) and to rule out PH (paroxysmal hemicrania). Still inconclusive as not suffered any bad headaches, just a more or less constant background "shadow" headache which the indo seems to help with. Have to stop course in a few weeks as only able to take for a max of 3 months due to high dosage and potential stomach ulcers etc. Dreading coming off it due to rebound headaches. Doesn't seem to help much with other pains such as back and joint which I have suffered recently, not sure if this is because it's a side effect of the meds. M 39 3 months
8/7/2008
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 4  Chronic Migraines I use this medication to get rid of migraines once they've started. It works amazingly quick in ending the migraine BUT...I get incredibly dizzy, nauseous, and feel like I'm incredibly high and feel like I'm slowly fading away or falling down, which makes walking difficult. I do eat w/it, but the side effects are a constant either way. It works great for migraines ...especially since I've tried several medications for this disorder. However, for first time users, I would recommend NOT taking this before needing to leave your house for work or school or something. The first time I took it I had to leave work and was hit so badly with disorientation I considered calling 911 at one point. F 26 3 months
75 1X AN
3/22/2011
 4  Pseudogout Stomach pain/cramping possible ulcer UNLESS taken with milk or antacid, then the stomach burning was reduced. Lightheadedness, dizziness, veritgo, naseau, and I have taken many medications in my life, but this is the first time I have had severe side effects to a medication. At first I did not notice any lightheadedness/dizziness. However, toward the last few weeks of the 3 months I have been taking this medication(have been on it for 3 months), I have been feeling exceptionally light-headed and dizzy right after taking a dose. This lasts for about 1.5 - 2 hours, and like others have noted, feels like you are on a roller-coaster/naseaus/motion sickness. I believe the LESS TIRED AND MORE FOOD I have when taking the dose, the MORE REDUCED are the SYMPTOMS F 42 3 months
50 mg 3X day
6/1/2010
 2  Torn Knee Meniscus MUST eat a decent sized meal before taking indomethacin - it is a very uncomfortable experience. Severe light-headedness, spacey, dizziness, groggy beyond belief, feels like all you want to do is sleep but so uncomfortable you can't. If you don't eat prior to consuming indo the above side effects are much worsened Despite the series of serious side effects I continued taking it because it eliminated the swelling in my knee and allowed me to walk without limping, and in general made moving easier. However, it can be dangerous as the side effects do not hit you until a couple hours later. I was driving and had to pull over and call my parents because of how uncomfortable/ light-headed I was, I was scared I couldn't safely make it home. As well, I was pretty much useless after taking it feels like you're underwater, GROGGY. I swear beside the word groggy in the dictionary should be the word indomethacin - all you can do is lay down and even that's really uncomfortable F 22 3 months
50MG 2X day
3/4/2017
 1  ankylosing spondilitis Dizziness, confusion, tiredness, headaches, light-headedness, frightening dreams & nightmares I took indomethacin for chronic hip pain, for a period of about three months. During that time, I was unable to perform to my normal standard at work, due to the dizziness and confusion the drug caused. Indomethacin did stop my hip pain, but I couldn't stand the side effects, so I have since switched to Voltaren. This drug works just as well on the pain, without the annoying mental effects. F 29 3 months
3/2/2007
 4  Paroxysmal Hemicrania Blood pounding through ears and head, stiff neck, canker sores (?), slight dizziness 10-15 minutes after taking pill This medicine has drastically reduced the frequency of my horrible headaches, but it does not block or fix smaller tension or stress headaches. When I first started this med. I would feel tightness in my chest for about 15 minutes, and then it would relax. This doesn't happen anymore. Now, I still sometimes have trouble with the sound and feeling of blood pulsing up into my head - very uncomfortable but usually goes away after I fall asleep, though sometimes this takes a long time. I had about 2 months of chronic canker sores on gums and tongue, but this may or may not have been caused by the drug, I'm not sure. They aren't occurring right now and I'm still taking the med. Overall it has been helpful. When the big headaches come it blocks the majority of the pain, but my body still goes through the headache so I still experience neck stiffness, vision changes, sensitivity to light and sound, nausea and vomiting and the need to sleep for much longer than usual. I have also experienced some weight gain while on this drug because it must be taken with a meal, not just a snack. I space out the times when I take it to cover as much of the waking day as possible, so I wind up eating 6-7 small meals each day. Is difficult when the last meal is at 10pm each night. F 37 4 months
75 4X day
6/16/2011
Email
 1   My neurologist prescribed this for my migraine, one pill twice a day for flare ups. First couple of doses fine. Eventually I developed severe psychiatric problems the day after a dose. My scalp and the inside of my mouth would tingle and I became hyper aware of them. Then I had obsessive type thoughts about bugs. I did not see or feel bugs but just thought about them all the time. I worried there might be bugs in my food, even my kids' hair and beds. I knew that there were no bugs, I just couldn't stop thinking about them, so more like OCD than psychosis. It effected my appetite to the point I was hardly eating. Severe diarrhea for 10+ days. Bad reaction and will never take again. Took 2-3 days for all symptoms except diarrhea to subside after I realized the connection. I see now that there is some evidence that this drug can make underlying mental health problems worse. Prescribers and pharmacists should really be aware of this potential reaction or effect. I actually tried to report my reaction to the FDA, left a detailed telephone message and no one ever called me back. F 42 4 months
Migraine 2X day
8/1/2021
 5  gout None noted I thought this a miracle drug for my gout. I also use 50mg PRN for severe lower back and muscle pain when OTC drugs no longer help. Will not take regularly, due to fear of eventual GI bleed. F 55 6 months
2/13/2009
 4  Hemicrania continua This medicine raised my blood pressure, I'm usually normal around 117/80, but everytime I went back for a check up my blood pressure would be elevated which they said could happen on this med, my last check up I was into the 140's This medicine worked for me , it gave me relief from my daily headache which hurt like hell even though I was still able to go to work and live my life normal, but now my BP is up I want to wean myself off this drug because I'm having anxiety knowing that my BP is high M 41 6 months
150mg
7/14/2017
 4  Ankle arthritis Some abdominal cramps at first use, not too bad recently. I use it weekly, for pain management. One day, 4 pills, and then no use for several days until pain gets bad again. I'm trying to avoid or postpone the need for an ankle fusion. Taking with food and lots of water reduces the cramping. M 58 6 months
25 4X day
6/24/2011
Email
 3  Headaches Dizzy, unfocused, fatigue, disoriented, dry-mouth, nausea, chest-tightness, feel like I might pass out When I started taking Indocin I would take it at night with antacid and didn't notice any issues. But then when I take it during the day (usually around lunchtime) I've experienced these side-effects that come on quickly and are nearly disabling for about 1-2 hours. I don't feel comfortable taking it anymore because of these side effects. F 53 6 months
75 mg 1X day
9/30/2014
 1  Bursitis in my hip Dizzy and lightheadedness I was initially on the green ones and seemed tolerable to a point but ended getting the blue and white ones after refill and weight gain fluid retention severe depression crying and feeling like loss of hope and interest pounding head when standing up from a sitting position really a feeling of being a failure and not who I know I am I've stopped it completely F 49 6 months
25 x2 dail 2X day
7/14/2022
Email
 5  Inflammation of Joints Dizziness, light headed, weight loss (40 Pounds) I take 100 MG of Indomethacin everyday (DAILY). I love this stuff and it has really reduced my overall joint pain. M 38 8 months
7/5/2009
Email
 5  Ankylosing Spondylitis Tiredness and lethargy if taken in the morning. Received diagnosis of AS after MRI and genetic blood testing. I also had a CAT scan that showed internal inflammation in right side. Extreme pain mostly in my back (all up and down my spine)and on my side. I was prescribed 75 mg. 2x daily but I am pain free with one pill at bedtime. This drug has been a miracle for me as I have experienced pain from age 23 until now. Prior to taking this drug I hadn't slept through the night in at least three years do to agonizing pain. I now sleep like a baby, totally pain free, and I can now work and exercise all I want during the day with no pain. F 38 8 months
5/26/2006

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