DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (144 Ratings)

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DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-MEDROL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  knee osteoarthritis None. The drug has been a miracle for me. Did not realize how much trouble I had walking before injection. F 70
40mg 1X day
9/9/2015
 4  Rheumatoid Arthritis Anxiety, hot flushes, stomach pain and nausea. ALL ARE TEMPORARY!! I have used various methods of steroids (infusions, oral, IM) and they all work great. Yes they do give you some unpleasant side effects but these are short term and what are they in comparison with extreme joint pain and stiffness?! The worst one personally experienced is anxiety. If you experience this, contact your GP and they can give you something to help. There are always drugs that can counter act the side effects so don't listen to the horror stories! Do what is best for you, don't be put off. F 20 6 years
120mg 1X AN
8/26/2015
 1  knee sprain The stiffness and soreness in my knee immediately returned. Like going back to square one. I only got the injection because I was going hiking for a week. The knee had nearly healed. A steroid shot had been recommended by another doctor for a previous sprain, and by friends who's had it. Instead of relieving the symptoms, it was like re-injuring the knee. M 65 9 days
1X AN
8/14/2015
 1  Seasonal allergy Irregular heart beat . Spiked Blood Pressure and anxiety. I would strongly recommend to avoid this unless you are really left with no choice. If I had known about these before I would have never taken them M 34 1 days
80
7/30/2015
 4  Knee osteoarthritis-degeneration Facial flushing; heartburn; irregular heartbeat All side effects from injection lasted only 2 days. The relief from my knee pain lasts almost 3 months. Get knees injected every 3 months for past 3 years and it is still working. Can put off knee replacement until injections no longer work. F 69 3 years
1X O
7/7/2015
 1  Allergies I was given the shot about 2 weeks ago and immediate reacted in doctors office with almost passing out, heart pounding and racing, and shaking uncontrollably. They gave me a shot of Benedryl which helped calm me down but have been in ER 2 times since with racing heart, feeling faint, BP has been up since and sugar elevated which I have never really had these symptoms until I took the shot. I hope this passes soon! They say I may have developed a anxiety disorder as a result. Try everything before taking a shot of this crap! M 39 1 days
40
5/26/2015
Email
 1  pain Very sick raised my blood pressure very very high my heart beating very fast my stamach sollen and side and the pain was in my left not my right side a rash on my arm and my right ankle burning with my gums sollen pain this is a very bad drug and the pain i haf the shot for is not even gone Drs should not use this for people in pain makes it worse now i just heard theres a recall on this drug so why did he use it that dr is going to get sued if i do not get better and so is the manfacturer. F 72 1 days
30mg
5/3/2015
Email
 2  Severe hip arthritis None - just some soreness for a day or two I was diagnosed with severe arthritis in my hip and was told I'd need a hip replacement at some point. The doc said I could get relief from these shots until they didn't work anymore, at which point I'd probably want to go ahead with the hip replacement. I had one 80 mg shot under a fluoroscope in Aug 2014, and it gave me almost complete pain relief for 8 weeks. I had another shot in Nov 2014, and it gave me no relief. I had a third shot March 2015, and I had relief for about 4 days before the pain returned. I'm now talking about hip replacement with my doctor. F 40
80 1X O
3/16/2015
 4  Severe asthma I have severe asthma and take 2 inhalers, 2 pills and a nebulizer on a daily basis to breathe. I get an 80mg shot of Depomedrol once every 30 days without the shot I end up in the ER because I can't breathe. Yes I have gained weight and get itchy at the injection site but I will take that any day over not being able to breathe. My Asthma is so severe, without the shot I feel like I have an elephant on my chest and then a panic attack because I feel I will die The shot relieves all of that for about 30 days. They need to work on the weight gain issues because breathing and fat don't go well together F 42 3 years
80mg month
1/21/2015
 1  Neck pain I received 3 epidural injections of Depo Medrol. Once a week for 3 weeks. I had reaction after 3rd. Waiting 15 minutes after injection before leaving office. I had taken Valium before procedure and dozed off. When I woke after the alarm went off, I could not move any part of my body and barely able to move my mouth to talk. They rushed me to room with oxygen etc and it took abt an hr and half before I had feeling again. I asked doctor what had happened. He said not sure maybe a reaction to numbing injection. Well after 1st injection severe pain at neck and unusual eating habits. I told doctor on 2nd visit. He said wow that's odd. 2nd injection I told him the same. No response. Well after the 3 they called and cancelled my 4th. So now 6 weeks later...i have gained 30 lbs, difficulty breathing, pain in whole body especially legs. I have had severe cognitive issues. Not remembering short term things especially. It seems some things have improve d, but others keep getting worse. I was 117 lbs when I started these epis. Now I'm miserable in pain and depressed. Does anyone know how long these epidurals stay in your system? F 40 3 weeks
50 mg
12/3/2014
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 1  hayfever I was giving depo medrone in jun 13 Oct 13 I noticed a dent in my hip now a year on its getting bigger I.v had xrays all was clear I am now getting physio to try and bulk my muscle back out but I am not happy as it might not work as my physio has told me.. Has anyone sued doctor or company for this side effect???????? I can't wear a fitted dress because you can see the dent in my hip 😞 I hate what it's done to me F 27 1 days
11/20/2014
Email
 1  Allergies EXTREME insomnia, EXTEME fatigue, anxiety, increased libido but unable to climax, the list goes on and on. My allergies became out of control while moving house (dust) so after a week of suffering I went to the dr hoping to get some relief. This was 2 days ago. I have had no relief from my allergies but that now fades into insignificance to the issues I now have. I have not slept since having the injection and have now been awake for more than 2 days. I can get a few minutes of dozing sleep in which I have strange dreams but can't get any deep sleep. Doing anything is very difficult even basic daily tasks. All I want to do is sleep but can't. I had to defer my uni exams because I am very sick and have no focus. My libido is out of control but I can't climax, this is very strange and frustrating. I have never felt worse and am very worried about what's to come. This drug is poison. Do not go near it with a 50 foot barge pole. I went back to my dr today who said that there are no side effects with this drug. What a load of crap! She even offered to give me another 40mg dose to try and help with my allergies to which I said NO!!!!! I would jump off a bridge before I would be injected with this poison again. STAY AWAY FROM THIS DRUG. If this post helps one person not to go near this drug it will be worthwhile. F 31 1 days
40mg 1X day
10/24/2014
Email
 4  Fibro, RA, OA, stenosis & sciatica Don't heal as quickly. Reduced sinus swelling, allergies better. Happened to Get shot in hip w/bursa swelling (20+yrs)- better, pain in lower back - better, pain from Fibro - less & less flares, arth pain - better & better life because of less pain, better motion & emotion! I live the life - 40yrs Fibro & back/hip pain many of u describe as side effect. I'm sorry that maybe dosage wrong or whatever reason it was a bad experience for u. I am so grateful my Dr cared enough to find something that helped me. I have to wait 30 more days, he says not good to take more than 3x's a yr, & I am counting down the days! F 56 6 months
20
9/2/2014
 1  BronchoSpasm (Asthma) I've had depo before and it never did this to me before. Extremely rapid heart beat, irregular heart beats, and fluttering heart with any movement (no endurance). Shallow breathing. Could not walk far without feeling my heart was about to burst. Could not swat a fly without my heart overreacting and going wild. Slightest emotion caused my heart to go wild. Felt like acid or fire running through my arm and neck veins. Twice I almost died. Felt like I was in the 7th circle of hell! Felt like fire, then antifreeze, running through every cell of my body with rapid heart. Muscle weakness. It has been 20 days since receiving the shot and I'm still having symptoms. Have not been able to walk through a department store without feeling like my heart can't handle it. Going to have a heart ultrasound to ensure depomedrol didn't blow my valves. Having been praying like crazy to get well. This stuff is poison! Never again!!! (He should have just given me steroids by mouth.) The labs making this stuff need to be inspected and cleaned up! F 57 1 days
80 mg 1X day
8/21/2014
Email
 1  pain. I recieved shot Rash 2 week then got rash week later F 1 days
40 mg
6/3/2014
Email
 1  Facet Joint Arthritis PANIC, ANXIETY, DEPRESSION, SKIN BURNING, HOT FLASHES, INSOMNIA THAT CAUSED WEIRD SEIZURE MOVEMENTS AFTER GOING DAYS WITHOUT SLEEP, ER VISITS, HOT FLASHES, PERIODS WENT CRAZY FOR MONTHS AND MONTHS!! NEEDED BENZO VALIUM TO KEEP FROM GOING INSANE!! I HATE BEING STUCK ON VALIUM!! Was FINE before shot!! Slept well, no anxiety before or during periods, no anxiety PERIOD!! The night of the shot I woke up with my whole body flushing..like my skin was on fire. I was BEGGING Jesus to help me. I began to have a panic attack, could not sleep, and felt like I was going to die. I suffered it out the night, got a little better, then thought drinking water would "FLUSH" the med...NOT!! I was told by family to give it a few days. I did not sleep and kept having SEVERE panic while trying to sleep. My body was jerking, felt like I was dying. After day two I went to the ER, the Doc felt really bad for me and said it WAS the steroid shot, and I would most likely feel better in a few weeks. NOPE!! In and out of a few ER's after going 3 days with no sleep each time and the anxiety was AWFUL!! Primary care doc told me to take some valium to help; it did a little but not much. She said some people have had this happen, but after a few months it goes away. Well...I am STILL suffering 1 year and 3 months later. After the first three months post injection, I HAD to find a psych dr., I have bad reactions to SSRI's and other psych meds apart from Valium...so he prescribed 5mg a day. After a week, I felt, ok so I thought I would ween off...BAD idea; symptoms came back. Tried to go back up on 5mg, but it no longer worked. Had to up to 10mg. Stayed on that for about 10 months or so, even on that dose...I had issues before and during my period with worse anxiety and s F 38 1 days
80mg 1X day
4/27/2014
Email
 1  Injected in foot for pain An hour after injection, I was on floor crying in pain. I had muscle spasms in my back for days, it was horrible the worst pain I have ever had. My dr told me it had nothing to do with shot and I will strongly disagree with that! F 17 1 days
3/17/2014
Email
 2  shouler pain torn labrum Had injections twice within a 4 month peroid. Servere cramping of all muscles. orthapedic doctor who did injections NEVER informed me of SIDE EFFECTS or AFTER CARE let alone what he was injecting! I think these injections are used very recklessly and are doing far more damage than good. After second injection ring finger has gone totally numb. Also pain in kidneys. M 43 1 days
injection
2/12/2014
 4  Inflammatory arthritis Headaches and soreness at injection site but only for a couple of days. Each dose lasts around 6 weeks each to help especially the pain and inflammation and fatigue F 37 2 months
120mg
12/31/2013
Email
 3  severe scalp psoroasis I had to get this injection because my scalp psoriasis was severely flared so I went to urgent care and that is when I heard of this injection. The Dr was explaining the shot to me and how it will work, he said it surpresses the immune system so I asked does that mean i m gonna get sick he said no its not as bad as it sounds so I got the shot Monday night Tuesday I woke up feeling great my head was so much better... Wednesday I woke up in the worse pain ever with strep throat fever flu symptoms... Thursday even worse than Wednesday so I went back to urgent care they said I got sick because the depo medrol surpresses ur immune system and I said I knew it was gonna happen so the gave me antibiotic injection and today is Saturday and its not as bad but it still hurts to swallow and my teeth seem sensitive hmmm kinda weird. I really don't know what was worse the psoriasis or my body feeling like I got hit by a bus... I still keep looking up as things could be worse. F 27 1 days
80mg
12/7/2013
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