ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Quit Smoking overwhelming feelings of despair, depressed mood, severe agitation, insomnia, paranoia, anxiety, irrational and scattered thought patterns, twitching limbs I am one of life's happy people - so having overwhelming feelings of despair and feeling depressed has been extremely confronting. This is my third or fourth attempt using Zyban. Only side effects I had during previous attempts were twitching limbs and a general feeling of well being. As I had taken Zyban numerous times before, I forgot to do slow build of 1 per day for 3 days, then 2 per day thereafter - especially as I was keen to quit. I just kicked off with 2 per day from day one. I think this may have contributed to the pronounced difference in my experience of the side effects. I have not smoked for 5 days (I am a pack a day committed smoker - it has been over ten years since I have not smoked this long. Even with patches on I would chain smoke). I have now reduced dose to 1 per day. If side effects have not diminished by next week, I will stop taking Zyban. I would rather stick with not smoking than endure these negative feelings again. It has given me a valuable insight into de F 40 11 days
1/21/2009
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 3  stop smoking severe diareha and vomiting. dizziness, light headed,sweats All was fine till the 4th day when I started 300mg. An hour after second dose I had ringing in the ears and stomach pain. Within two hours I was throwing up. I threw up every hour for 12 hours the every 3-4 hours. Diareha started somewhere in the 12 hours I was vomiting. Have not thrown up in 12 hours now. Still have bad diareha, Have not smoked in almost two days. Have stopped taking zyban for now. I will be cutting dose down to 150mg as soon as I am feeling better. F 38 5 days
1/14/2009
 1  stop smoking paranoid angry loss of concentration didnt want to go outside and had to be admitted to hospital for mental health problems that didnt have before taking zyban i am commenting on behalf of my ex partner of 20 years he took zyban in 2001 and was never the same he commited suicide july 2008 F 37 30 days
1/10/2009
 5  stop smoking I wrote my previous comment on 8/14/2008, you can see all the side-effects I had. It was truly hard for a week. I can say that after 4 months as an ex-smoker, I'm terribly happy I used Zyban. It helped a lot. People smoke in front of me & I don't feel any craving. I am thoroughly detached from smoking. I rarely thought about it during the last months and when I did it was piece of cake to overcome the craving. I just want to add it takes some personal strength to use Zyban, and I promise I'll be back as soon as I accomplish 1 year as an ex-smoker to tell you all. M 44 9 weeks
12/4/2008
 1  Smoking Cessessation Insomnia, Dry eyes, extremely vivid dreams, self-harm thoughts. Immediately flushed the entire zyban prescription the day after the self-harm thoughts occurred. Never have had them in my life, extremely scary. I recommended trying an alternative to quit smoking before trying to use Zyban. Extremely risky. BE CAREFUL!!!!! M 20 4 days
11/28/2008
 5  Stop Smoking Slight restless sleep and a bit of a dry mouth. Gone from 20 a day to 2 a day and I have not reached my quit date yet, I have not had any of the side effects described other than a few minor things as described. Give up day is Thursday and I am feeling positive about it. I am keeping a blog of my experience on the drug: zyban-media-hyped-placebo.blogspot.com/ There is still a long way to go but so far so good! M 27 6 days
11/11/2008
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 5  Stop Smoking Currently it is my 3rd day on Zyban. I havent slept more than 2 hours in 3 days. Today I have a headache and a terrible taste in my mouth. I feel disconnected to the world to a large degree. I am in a state of panic about some side effects. Suicide, etc. Today i feel disgusted by smoking. The taste is terrible. Reminds me of my first smoke. So far so good. I imagine that once it has managed to "even" out in my system many of the side effects will go. I am looking forward to being a non smoker and having control of my life again. I have been smoking for 10 yrs and started young. I am proud of my steps F 22 3 days
10/23/2008
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 5  To Stop smoking October 30th will be one year that I quit smoking with ZYBAN!! All the side affects that people wrote were not so for me.I just re-read what I wrote Nov 6/07 & still stand by it. As for not drinking alcohol...the ONLY problem is that beer tastes bad as well. But tough it out & you'll feel great!! Thanks ZYBAN!!!! Zyban's great.. F 37 12 months
10/21/2008
 5  Quit smoking Vivid dreams that were not at all unpleasant. A bit of dry month. I wish I had taken this before I stopped smoking. I quit cold turkey for two months after 40 years of smoking. I soon had a serious case of insomnia that led to major depression. After 10 days on this drug, I started sleeping OK, and was more or less functional. That's on 150 mg. That was enough to do the trick, so I didn't up it to 300. M 65 2 months
10/17/2008
 5  To quit 20 year smoking habit I am on day 16 of the Zyban program. I had no side effects the first week but I am at home from work now with bouts of nausia and cold and clamy sweats and constipation with large amounts of gas cramps. I have felt dizzy and had very dry eyes. I have had mild cravings that only last a few moments. Have been smoke free for 5 day's. I am amazed at how well this medication works, I just wish the side effects weren't so bothersome. I was sitting beside my co-workers while they were smoking and had no urges to smoke. This is my third day of missed work. The cramping is so painful and the cold sweats are imbarasing. I have noticed that my urine has a medicinal odor to it. Yuck. I wish this medication was covered because @ 80.00 a month it's expensive. F 31 19 days
10/8/2008
 4  Stop Smoking I had insomnia (took over the counter sleep aids, worked like a charm), crazy dreams, dry mouth, a bit of anxiety, increased urination (probably due to all the water I was drinking), a drab sort of "whatever" feeling. I'm 7 days into Zyban. I started feeling the side effects when I upped the dosage to 300mg. I quit smoking 5 days into the treatment. So far it has worked. My head sometimes hurts but I haven't had any side effects I can't handle. From most of the (positive) posts, side effects subside in the first 2 - 2.5 weeks. I do have a weird sort of 'whatever' feeling. Kind of a lack of caring about stuff yet I still manage to put 110% into it. I've had some weird thoughts but nothing totally out there. Me and the girlfriend split a few days ago and I never really took it too hard. I usually do. Maybe that's the antidepressant characteristics of this drug kicking in (we never ended things because of the Zyban). I think I'll avoid alcohol for a while just in case. I took sleep aids after I upped the dosage to 300mg as I couldn't sleep a few nights. Since then I've switched to taking herbal Valerian Root to get to sleep. If history repeats itself, in a few days I should be able to M 21 7 days
9/11/2008
 5  quit smoking Insomnia, agitation, spasms, heart palpitation (during the 2 days after quitting, possibly the cold turkey), anxiety, dry mouth, “astral-trip” mementoes (vertigo crisis in a movie theatre), feeling livelier and more active than usual, and last but not least a very positive response to hangovers the morning after ! Quitted 12 days into the treatment. On day 11 I had smoked a pack and a half plus drunk many beers so I thought it’d be impossible to quit. On day 12, miraculously, I experienced the total absence of craving for a ciggy (and no hangover at all to boot). The worst came on day 13 and day 14: the side effects accelerated. I had insomnia, palpitations (cold turkey?), an almost permanent state of anxiety and dizziness, and my nerves were at the end of their tether. I decided then to cut to 1 pill a day but eventually I didn’t, and on day 15 things came suddenly back to normal and gradually getting better until the last 4 days that I've been feeling perfectly normal. I'm on day 10 after quitting and frankly I have no cravings at all. If the side effects don't come back this is going to be easier than expected and I'd accept the side effects for a good cause. Essential also to steel your will and decide to become an ex-smoker, Zyban won't do everything. Reading Allen Carr during t M 44 21 days
8/14/2008
 4  Smoking Mild twitching in right eye, other than that none Completely rid of any craving thus far except after a drink..Feel fine too none of these bad side affects at the mo M 28 14 days
7/29/2008
 2  to quit smoking Anger, frustration, agitation, vivid wierd dreams, sadness and paranoia. I have hardly smoked in the past couple of months thats the good part. The first few weeks found it really hard to sleep. Soon after that I have been feeling sad and a bit confused. One day i felt i was going insane (PARANOID). I have been angry and agitated and everything pisses me of. Have beed violent(i do sometimes get kranky but nothing like this) my partner has been in tears because of me and the things i have said."she is an angel and i have been downright evil. This isnt me. IT IS SCARY. I have taken this before about 8 or 9 years ago and the symptoms were just physical and gave up for 6 months. In my opinion it is good for giving up the smokes but i think cold turkey is the way to go. Just think about it GIVE UP OR DIE. Good luck from CS M 30 2.5 months
7/29/2008
 1  Stop smoking Feel totally "spaced-out" - like my brain is being re-wired! Not safe to drive - concentration a problem. Easily agitated. Panic attacks. Dry mouth. Headache. All this on only 150 mg a day.... Amazed that this drug is still on the market! Does help alleviate withdrawal symptoms but if the short-term experience is this bad, I'd be afraid - very afraid. Stopping tomorrow before my brain becomes completely cooked! F 42 5 days
7/7/2008
 4  quit smoking The first three days I didn't feel anything at all, I think it actually made me want to smoke more. After the first week i felt anxious all the time and one night the anxiety got so bad I was freaking out and I am normally a very calm rational person. The next day though I woke up and didn't want a cigarette so I stopped taking it. F 23 12 days
6/14/2008
 5  Quit Smoking A little bit of Sadness, Difficulty Sleeping, Feeling Dazed, Uncomfortable at First, Not feeling like myself When I first started taking zyban, I thought I wasn't going to be able to use this product, I had trouble sleeping, was feeling sad and lonely, and also feeling dazed or stoned something like that. I decided to keep trying for 2 weeks and if I didn't get used to it I would stop. Well I am now on day 16, not smoking, sleeping perfectly and feel absolutly normal. I'm not saying it will work for all but if you can just get through the beginning side effects, I think it will also work for you. Just remember your body will always have an adjusting time to each different drug. It took about 10 days for my body to adjust, and like I said, I feel totally normal and fine. Good Luck, if you have any questions you can email me. F 25 16 days
6/6/2008
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 5  To quit smoking The only side effect that I experienced was dry mouth. It has helped me a great deal. I've smoked over a pack a day for the last 30 years. I am down to 2 cigarettes a day. Having trouble taking that final step to quit completely, but I will do it. F 48 2 months
6/4/2008
 3  depression In the very beginning, nausea-- intense brief waves of nausea. The nausea went away after the first few weeks. Overall side effects include mproved sleep, constipation, feeling a bit jittery, stressed, slight weight gain (few lbs). Since starting this drug I've also been experiencing a lot of yeast infections, which is NOT normal for me (approx. in 5 months). I tried several OTC treatments, pill from my physician but they keep coming back. I am wondering if it is related to the drug...but I haven't seen anything in the literature. I am planning to go off the drug to see if it helps. F 32 5 months
6/3/2008
 4  As an aid to stop smoking. PLEASE READ. Zyban certainly did what my doctor said it would do, that is, take away the extreme withdrawal symptoms of quitting. Before anybody commences a Zyban program, I would recommend that all support programs are put into place and that loved ones are warned about possible outcomes. I have read most, if not all responses and would suggest that there is a large amount of truth in ALL. Be aware that Alan Carr's book along with Zyban and sheer willpower should achieve the results you want, however the side effects of Zyban really do need to be considered. Note: If you really want to get divorced, hook into the Zyban immediately. M 48 8 weeks
6/1/2008
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