EFUDEX Reviews (FLUOROURACIL)

Average Rating: 3.5 (45 Ratings)

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 DERMATOLOGICS

 Type: Rx Drug

  

EFUDEX  (FLUOROURACIL):  This medication is used on the skin to treat pre-cancerous and cancerous skin growths. Fluorouracil belongs to a class of medications known as anti-metabolites. It works by blocking the growth of abnormal cells that cause the skin condition.   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3


 

RATING  REASONSIDE EFFECTS FOR EFUDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  actinic keratoses very tight and feels like it's burning. very itchy. hope it works! F 78 13 days
40 gm 2X day
3/14/2010
 5  actinic keratosis Does this stuff make you fatigued and sleepy? Because I started it 4 days ago and am perpetually exhausted. Otherwise, minor dryness 5 days in, and sweaty greasy feeling where applied. I am applying morning and night all over face to eliminate actinic keratosis and possible BCC, to which I am prone. So far, no big reactions, just dryness and slight itchiness. But I am exhausted and can't seem to sleep enough, have trouble arising and functioning with fewer than 9 hours of sleep. Can a topical agent do this? After all, fluorouracil is powerful stuff. Can it get into the bloodstream? Anyone else have this happen? F 54 5 days
10/14/2008
 5  BCC's and AK's Intense burning and itching. Rash spreading into adjacent untreated areas. I have been using Efudex 5% solution for about 10 years. It was originally prescribed to treat an area on my forehead after a BCC had been scraped off. Since then I have used it on other suspicious areas of my face, arms, and legs with great success. I recently got a new prescription for the generic 5% cream and used it on my chest for about 12 days. After I stopped the treatment, my chest started to burn. Everything I put on it just made it burn more. Then I got a rash all over my chest and on my neck in areas that weren't even treated, and nothing I tried for the itching did any good. I also used it on several areas of my face and one on my shoulder, but these areas did not have such a severe reaction. The ones on my face are almost back to normal, and I am still treating the one on my shoulder, but my chest is still very red and itchy. F 58 19 days
9/21/2008
 4  skin cancer Not exactly a side effect - it made my skin feel like I had a bad sunburn, and the area on my face where it had been applied looked like I had a blotchy sunburn. This is apparently the reaction that is expected. My doctor said "Apply it for two weeks, or as long as you can stand it. It will feel like you have a bad sunburn." It did a pretty good job of clearing up some cancerous and pre-cancerous areas. These are usually squamous type cancer in my case. I've had twenty or so removed surgically, but the doctor thought that using Efudex would reduce the amount of surgery necessary. According to the package insert, Efudex is about 80% effective. Some of the spots cleared up by Efudex have returned in my case - about four months after using it. I applied it to my face in quadrants - two weeks per quadrant. M 73
7/18/2008
 5   Essentially no side effects. The cream will cause the precancerous area to turn red and crusty. After 4 weeks of treatment I feel comfortable knowing that it has removed any potential cancer cells. M 57 30 days
4/5/2007

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