DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2474 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  For use by females of reproductive potential to prevent pregnancy. Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is also used with or after other treatments (such as radiation, surgery).   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  FDA Adverse Event Summary

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  birth control Viginal dryness (I'm 99% sure it's because of depo); aching and cracking joints and bones (I'm only 29, I feel like an old lady); difficulty maintaining weight; irrational moods. I have been on depo a few times for about a year each time and then come off it for perhaps a year. I do not have any bleeding with it which is one up side, the other up side is contraceptive. I'm convinced it's the depo which makes me feel depressed, angry and irrational, I wasn't like this before and I have no circumstances for feeling that way. I find I feel happier about 10 to 12 weeks after the injection and am seriously thinking of coming off it, and to hell if I get pregnant (although my boyfriend will not be pleased). I go to the gym 2-3 times a week, do yoga, and walk a lot. If I have a few days off from exercise my weight creeps up, even though I only eat 3 healthy meals a day and don't drink much alcohol. I'm also worried that if I stay on it for too long it will affect my fertility and I really want kids in about 2 years time. I have few alternatives: The pop pill gave me excrutiating breast pain, the mini pill cannot be prescribed because I have occasional migraine F 29 18 months
12/13/2006
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 2  Birth control severe acne, loss of libido, weight flunctuations I'm a new user, I'm due for my 2nd shot next week however I'm going to ask to be switched to something else. Ever since started depo, I've had a severe acne problem. I've never had severe acne, not even when I was a teen. I've spent a fortune in scrubs, lotions, kits, stringents, soaps, and everything else imaginable to clear up my skin without much luck. Also, Before depo I was a very (some would say overly) sexually active person and since taking it I've had almost no interest in sex. I haven't had any weight gain, but before starting Depo I was actively trying to lose and had lost 20lbs. I hoped if I just stepped up my weight loss routine the depo wouldn't effect it too much, but no such luck. I went from losing 2-3 pounds a week, to gaining and losing the same 3 pounds for 3 months. I was thinking about giving it another 3 months, but I just rather get something else and let all this stuff clear up. F 21 3 months
12/13/2006
 1  BC while i was nursing MAJOR weight gain, loss of sex drive I started the shot 2 months after I gave birth to my son. It was the only hormonal BC that is safe while nursing an infant. When I started the shot I was back to my normal weight, 120lbs(at 5'2 tall). After the first shot I noticed a slight but steady incline in my weight, then all of the sudden, almost over night I seemed to gain 25+ lbs. I know this isn't due to poor diet or lack of exercise. My husband and I are very active at the gym and eat very well. Recently I went to a new general practiner(we moved to another area) who seemed certain the weight gain was from the shot. He told me I didn't have a lot of body fat and that it was water weight that should come off once the shot wore off. My last shot was due over a month ago and needless to say, I didn't get it. Now I'm just waiting for my period to restart. My doctor told me once I get my period that's a sign the depo is out of my system. Although he did advise me it could take several months. F 26 8 months
12/12/2006
 1  help with heavy bleeding extreme weight gain, decreased sex drive, no lubrication, mood swings, constant bleeding I took the shot three times, and was told that it was my last option to control my extreme bleeding before going on lupron. I still wanted more kids, but was not told about the extreme side effects of taking this medication. Now I have been off of it for 6 months and have only had one light period over two months ago. I feel miserable, and don't know how long I can take this. F 25 9 months
12/11/2006
 5  As BC and for period relief Bone pain, muscle pain, acne, weight gain, fatigue, MS type symptoms. I think it makes for a horrible person to make fun of people who had bad side effects or call them crazy or names. All medicine effects everyone differently...so you don't know what you are talking about and just shouldn't speak. I loved the Depo...I was on it for 7 years. It was great for me. I had big problems with my period and it solved that. I too had the side effects and extensive testing to figure out what was wrong...and was told it wasn't the Depo. I weighed 94 lbs starting...went to 130 over the 7 years...thought it was age...stopped it and lost 30 lbs in 3 months! I feel better, but went right back to period problems. My 37 year old brother had a massive stroke a few months ago...so now they don't want me on anything. While I feel so much better off of it...I would have stayed on it if I didn't have that risk, as long as I knew what was causing my horrible problems...and now just happy to know I don't have MS! Some tests indicated I did...so there is medical proof of the changes it causes to your body. No one is crazy here...it is a massive drug...some can take it and love it, some cannot...and when you can't it is for real valid reasons. F 35 7 years
12/10/2006
 3   Among several was the loss of a sex drive...actually the thought of dating completely turned me off for many years. So I guess it really is a good form of birth control!! They give this drug to men in prison to suspend their libido. So, this is a serious thing to think about. If it really does this to you, it can effect your relationships and your emotional well being. The other side effects are all individualized as you can see in here. I have noticed in my situation that the longer I was on it the worse they became. My first two years were great. Years 3-6 everything seemed to occur. The FDA recommends only using it for 2 years...so it is a good choice for a short term resolution. F 34 6 years
12/10/2006
 1  to not get pregnant duh!!! i had gain soooo much weight, im depressed, im constantly having mood swings, i get eaily angry and bitchy, i used to weight a comfortablt 160ish pounds and now im close to 195 and extremely not comfortable with it. i took depo after i had my second child and there was no losing the baby weight and ontop of that i gained weight from the depo shot and got all the BS and came with it i got mood swings, and depression, i cant sleep at night, im constantly restless at night and cant sleep, i cant concentrate on anything and i feel constantly annxious. I DO NOT RECOMEND THIS AT ALL AND I HATE THIS PRODICT AND WILL NEVER TAKE IT AGAIN. THIS PRODUCT SUCKS.!!! IM SORRY FOR ALL THAT HAVE TAKEN THIS AND HAD ISSUES WITH IT. AN DFOR THOSE WHO HAVE TAKEN IT AND LOVE IT...UR ASS IS LUCKY U DIDNT GET ALL THEM SIDE EFFECTS. F 24 6 months
12/5/2006
 1  PAINFUL AND IRREGULAR MENSTRUATION I was on Depo for 4 yrs. The worst thing that ever happened to me. I had severe mood swings, depression, anxiety, anger, extreme vaginal dryness to the point of sex being painful, headaches, lethargy, and 60!!! pound weight gain. It took me TWO YEARs after getting off of it to get a normal cycle, and here I am five years later and been trying to get pregnant for two and NOTHING! I am somewhat convinced it made me sterile. My new gyno tells me that basically one of my ovaries is not ovulating any more and my periods are worse then they were before I went on it. I was also told when I got off of it that the weight should fall off and I never lost any of it, and have been trying off and on for five years and can't get past 15 pounds off. DO not take it! F 29 4 years
11/30/2006
 5  Birth Control and cramps weight gain, hair loss I have been taking DEPO for almost a year and i am very happy with it. I dont have my periods and i dont have to worry about taking the pill. I do shed alot but i dont know if the only reason is the shot, also i have gained about 5 lbs. since i have been on it. But over all i love the shot because it is so much easier to remember and it works for me. F 17 1 years
11/29/2006
 2  birth control Depression with no history or family history and no external reason, 55 lb weight gain in 2 yrs. Can eat and eat and eat and you never feel full. Don't take it! F 27 2 years
11/28/2006
 1  dr recommended I am so scared for my 18 year old daughter, she is having heart problems, shortness of breath, sick all the time, can't keep food down,swollen breasts, depressed, crying all the time, she is not the same person she was 4 weeks ago, i am so mad at doctor for recommending this to her, she looks so sick and pale all the time and he says oh, i guess this isn't for you, but too bad you'll just have to ride it out! This stuff is so,so,so BAD!!!! She has lost her job and doesn't feel like doing anything, she has no energy and just lays around almost in a daze, I am so angry! this drug should not be out there F 18 4 weeks
11/21/2006
 3  SIMPLE birth control Constant spotting, severely decreased sex drive, increased appetite, and possibly mood swings (I am a girl!). I've only been using depo provera for 7-8 months, so I'm hanging in there for a few more shots... but this spotting has got to stop! I don't have menstrual CYCLES anymore, just really light bleeding EVERY DAY. I'd stop right away because I hate bleeding during sex, but I barely have a sex drive from the shot anyway. I only like and use Depo because it is so incredibly simple. F 18 8 months
11/20/2006
 1  to prevent pregnancy Severe depression and anxiety, always fighting with my boyfriend..always crying,moody,easily set off, lost my job because i was always in a bad mood, irritable. I've had pregnancy like symptoms, I almost always have a period. I took it in april 2006 and its now november 2006 and i am still not back to normal, I only took the shot once. I feel like im pregnant Im spotting like pregnant people do, my breasts are sometimes tender, im anxious all the time. My boyfriend of a year cant stand me anymore. Im scared to death all the time cause I feel like im pregnant even though a pregnancy test told me I wasn't. If anyone has any of the same symptoms as me I'd really like someone to talk to. This is really hard for me. you can e-mail me at [email protected] F 18 1 times
11/19/2006
Email
 1  Birth Control EXTREME joint pain (hips, shoulders, elbows) and muscle pain (especially back of neck, side of neck, shoulders and muscles under the breasts). I had only two shots when I realized it had to be the medication causing my symptoms. I was a fairly healthy ex-dancer (i.e., I was limber and familiar with my body's response to muscle pain)in a very happy, stress-free time of life, yet months after meeting the man of my dreams I didn't want to have sex anymore because I woke up every morning in great pain in my joints. Nothing in my lifestyle had changed except a)I was happier and b) I was on this medicine. An internet search immediately indicated that joint/muscle pain was a common side effect, a fact never mentioned in the literature or by the folks at Planned Parenthood, who I generally trusted completely. Also my periods stopped for months, but I was warned that might happen. While I stopped the shots, the joint and muscle pain (esp. neck) are still with me, more than two years later! F 41 6 months
11/18/2006
 1  birth control decreased sex drive, non-stop heavy bleeding, excessive weight loss, hair loss, photo sinsativity- causing small blisters on my skin exposed to the sun, hair groth on chest, pannic attacks, and probably more that i was unaware of due to more severe side effects! I TOOK DEPO TO PREVENT GETTING PREGNANT A SECOND TIME. I WAS ONLY 17 AN HAD NO IDEA OF CHECKING SOMETHING OUT AND I TRUSTED MY DOCTOR. I HAVE TYPE ONE DIABETIES AND HAVE BEEN INSULIN DEPENDANT SCINCE 15. I BECAME PR EGNANT AND THEN HAD MY SON. MY DOCTOR INSTISTED I TAKE DEPO AND (NOT HAVE ANY MORE KIDS) DUE TO THIS AND OTHER HEALTTH PROBLEMS. SO I DID. WITHIN THREE DAYS I COULDN'T EVEN GO OUTSIDE IN THE SUN BECAUSE EVERY TIME I DID I GOT BLISTERS. MY HAIR BEGAN TO FALL OUT SO FAST I STARTED TO GET BALD SPOTS. MY DOCTOR TOLD ME THAT IT WAS HORMONAL AND THAT I NEEDED TO GIVE IT TIME. I WAS SOAKING ABOUT A PAD EVERY 2 TO 2& 1/2 HOURS. ONE THING IS FOR SURE IT WORKED FOR BIRTHCONTROL! THERE WAS SO MUCH BLOOD I WOULDN'T EVEN THINK ABOUT SEX. I STILL HAVE SCARS ON MY SKIN FROM THE BLISTERS TEN YEARS LATER. THIS WAS A VERY DANGEROUS AND TERRIBLE EXPERENCE FOR ME. I TRUSTED MY DOC AND I SHOULD HAVE RESEARCHED IT MYSELF FIRST! IF I WOULD HAVE KNOWN ABOUT HALF OF THE SIDEEFFECTS I WOULDN'T F 27 3 months
11/15/2006
 1  birth contol Bleeding, No weight gain, Very Moody 1 1/2 weeks after first shot started bleeding and have been bleeding now for over 2 months. I have gone to the doctor several times and they are trying different medications to try to get the bleeding under control. After shot I became very moody. Did not gain any weight. I will absolutely not be getting another shot. F 40 3 months
11/15/2006
 5  BIRTH CONTROL MAYBE SLIGHT DECREASE IN SEX DRIVE/ NO PERIOD/ HEADACHES THAT MAY OR MAY NOT BE FROM SHOT BEEN ON DEPO FOR 10 YAERS. OFF TWICE TO HAVE MY CHILDREN. WHICH I HAD NO PROBLEM GETTING PREGNANT IN THE FIRST TWO MONTHS OFF SHOT. LOVE NOT HAVING PERODS, AND NOT HAVING TO WORRY ABOUT DOUBLING UP ON A PILL THAT I FORGOT, AND WAITING ANOTHER WEEK TO HAVE SEX WITH MY HUSBAND IN FEAR OF GETTING PREGNANT.HAVE TO TAKE EXTRA CALCIUM, BUT WORTH IT. WAS HEAVY WHEN STARTED TAKING SHOT, CANT SAY SHOT HAS MADE ME GAIN OR LOSE AT ANY TIME. MY HUSBAND DOESNT LIKE THE IDEA OF THE SHOT, BUT IT'S THE ONLY BIRTH CONTROL, I FEEL SAFE WITH. HOPE EVERYONE WHO HAS BAD SIDE EFFECTS, CAN FIND A GOOD METHOD FOR THEM. I FOUND MINE!!!! F 28 10 years
11/14/2006
 1  birth control suicidality, dissociation, horrible, horrible, horrible. lay in bed for two straight weeks crying. just awful stuff. Depo is a nightmare, or at least it was for me. I got on it because of the appeal of ease of use and infrequent periods. I got one shot and it took me six months before I felt like I was back to normal, or because I got a period again. I did suffer from depression before taking it, and took the antidepressant Lexapro, which controlled my depressive symptoms quite well. Even though I continued to take Lexapro while on Depo, the depression came back worse than ever. One day I walked into the bathroom and swallowed every pill in the medicine cabinet and woke up three days later in the ICU. I am CERTAIN this never would have happened without the Depo. I felt like it took away my brain. I really cannot begin to explain what a nightmare this medication was for me. If you have ANY history of depression, DO NOT take it. F 35 3 months
11/11/2006
 1  birth control bleeding constantly F 17
11/6/2006
 1  Easier than taking a pill never ending period, mood swings, decreased sex drive, migraines, nausea, and weight gain I wouldn't recommend this form of birth control to anyone. It has caused severe mood swings and irritability that has caused a stressful marriage. My sex drive is decreased, and I have had a significant weight gain that has caused lack of confidence and self esteem. I have recently experienced horrible migraines due to this drug. I do not advise anyone to take the depo shot. YUCKY side effects. There is always a chance of a non-stop period like I had while on it. F 21 1 years
11/3/2006

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