DEPO-MEDROL Reviews (METHYLPREDNISOLONE ACETATE)

Average Rating: 1.9 (145 Ratings)

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 Type: Rx Drug

  

DEPO-MEDROL  (METHYLPREDNISOLONE ACETATE):  Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders.   (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR DEPO-MEDROLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  severe scalp psoroasis I had to get this injection because my scalp psoriasis was severely flared so I went to urgent care and that is when I heard of this injection. The Dr was explaining the shot to me and how it will work, he said it surpresses the immune system so I asked does that mean i m gonna get sick he said no its not as bad as it sounds so I got the shot Monday night Tuesday I woke up feeling great my head was so much better... Wednesday I woke up in the worse pain ever with strep throat fever flu symptoms... Thursday even worse than Wednesday so I went back to urgent care they said I got sick because the depo medrol surpresses ur immune system and I said I knew it was gonna happen so the gave me antibiotic injection and today is Saturday and its not as bad but it still hurts to swallow and my teeth seem sensitive hmmm kinda weird. I really don't know what was worse the psoriasis or my body feeling like I got hit by a bus... I still keep looking up as things could be worse. F 27 1 days
80mg
12/7/2013
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 1  Legg-Calve-Perthes Disease Hip pain Had injection in hip joint for pain related to childhood bone disease. It has been causing arthritis in the hip and residual pain in my back. Right after shot was limping. Lidocaine used with injection made no difference, increased pain began immediately and worsened. Can't find a comfortable position to stand, sit, or lay in. Pain is intolerable from my hip the whole way down to the middle of my calf. Muscles feel sore and achy, knee joint hurts when still or bending. At some points leg cannot bear any weight. Have tried both NSAID and narcotic pain relievers with no success. Was told this "doesn't generally happen" and clearly, from the ratings on this site and others, it does happen. Just say no!!! F 28 1 days
20mg
10/30/2013
 1  wrist pain Pain in my hand and arm..got worse each day. I took the shot about a week ago. And the pain is worse when I make a first with my hand. F 23 1 days
40mg
9/11/2013
 1  shoulder pain I was given a shot of this in my shoulder. Within 2 days i developed severe anxiety, heart palps,cramps in both legs,both arms,extreme next and upper back pain,eye twitching,ears ringing,chin and left face twitching,burning mouth and tounge,lips,weight loss, blue toes...For eight months these symptoms went on. It is now a year and my mouth still burns and face still feels odd. Countless doctors,spinal tap yielded nothing. No doctor but my dentist will admit it was the depo medrol. Very active woman who is an endurance horse rider and runner. Life was nearly shattered because of this drug! F 48 1 days
80mg
8/26/2013
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 1  Knee Pain I have taken this injection in my left knee, after taking injection within half-an hours time it was reacted, I got swelling complete knee area and sevior pain, and muscle was weaken. Now I am suffering with 10 times more pain than compared to before taking this injection, after two months also the swelling was not gone. Be aware before taking this injection. M 38 2 months
1X O
8/22/2013
 1  intramuscular injection/back pain Total body melt down and over a year later, still have side effects. Vision problems, nerve pain all over, weight loss, hair loss, digestive issues, continuous menstrual bleeding for about 8 months, the list goes on . . . seriously frightening medication. Be careful with this medication, do your homework in advance. To the angry reviewer a couple of reviews down, berating women for confusing Depo Medrol with some other drug, sounds like you're having some steroid rage issues. Yet another common side effect. F 33 1 days
40 1X day
7/1/2013
 5  Spring season allergy Increase of libido M 51 5 years
5/4/2013
 3  Allergic reaction to antibiotics First of all, all you young women on here bashing this drug because you claim you used it for "contraception"...get off the Internet, pay attention at your practitioner's office and find out what you are REALLY putting in your body. You're so damned ignorant! Depo medrol is a corticosteroid, not a contraceptive. You women are probably on Depo-provera which is A COMPLETELY different type of drug. If you morons payed more attention to what's going on perhaps you would be in better health, rather than broadcasting your stupidity over the Internet. F 32 1 days
4/29/2013
 5  Rheumatoid arthritis Is the only drug to get my RA under control suring pregnancy, while breastfeeding and until my other drugs kick in. If you are complaining about the side effects you obviously didnt need it to start with. F 2 years
120mg 1X M
2/21/2013
 1  Thumb Tendonitis Complete numbness of thumb for 3 days, after which I lost about 60% of sensation in my WHOLE body, particularly my scalp, face, neck, teeth, butt and back. Doctor says that my symptoms have nothing to do with the injection, but the numbness spread from my thumb all over my body. It has been a week now and I am not regaining sensation. I am very nervous and hope that something wasn't seriously damaged. I can't tell if my tendonitis is better because I can't quite feel anything on my body. F 30 1 days
unsure 1X O
12/11/2012
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 1  Allergy-Poison OAK I got the shot in my hip. The next day my back started hurting. It's been three days now, I still have my Allergy and my back feels as though its being crushed. I am in so much pain! Almost constant muscle spasms in the mid section by spine and rib area. F 44 1 days
40 MG 1X day
12/10/2012
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 2  Pleurisy I had an allergic reaction to this medicine. I got a fever and chills from it and now I have pain in the injection site that has not gone away. It hurts really bad to touch the spot. F 22 1 days
80 ml
12/7/2012
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 1  supposed trigger point in back Update from 7.5.12, 7.10.12, 7.18.12 postings: side effects of pain in extremities persist as well as extreme fatigue and muscle weakness. Also, the injection had no therapeutic effect whatsoever. It seems there is a common, scenario - what I experienced along with many others - that makes me wonder about the competence of doctors who administer these injections: doctors not informing patients in advance about possible long-term, serious side effects; doctors being far too cavalier in administering these injections; doctors denying side effects patients experience (some patients are told that they have "anxiety issues" or it's all in their heads! - read reviews elsewhere, the level of medical incompetence is truly amazing); and doctors being completely uneducated about side effects. PLEASE, everyone who has experienced serious adverse reactions to corticosteroid injections, file a report with the FDA: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053074.htm or call the FDA at 1-800-FDA-1088 to report by telephone. I had trouble filing online and sent a hardcopy to the FDA (which was acknowledged by letter from the FDA). Lawsuits are very difficult to bring, and the only way to force responsible administration of these potent drugs is for EVERYONE who has suffered serious side effects to report to the FDA. Corticosteroid use (abuse) is now booming business for doctors and drug companies, and it seems that the administration of these drugs has become unbelievably irresponsible. MANY people are suffering from the cavalier administration of corticosteroid injections and you can help put an end to the irresponsible administration of these medications by reporting your experience to the FDA. F 44 1 days
20 mg 1X day
9/29/2012
 1  osteoarthritis in hip Increased muscle pain at injection, uncontrollable sweating, anxiety, depression and dizziness. I will never take this again - did not help much with pain and side effects are worse than before I had injection. F 44 1 times
80mg 1X O
9/28/2012
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 1  ESI for bulging disc Insomnia, muscle weakness, cramps all over, menstrual irregularities, GI problems, extreme fatigue, hair loss, nerve pain going on 6 months now since last injection. Not warned of any serious side effects when I specifically asked and docs later denied any connection between injection and side effects. Google article “Understanding Potential Complications Of Epidural Steroid Injections: Practitioners need to understand and educate their patients regarding the full scope of potential side effects that can occur when receiving epidural steroids." The article states: “Despite the indisputable rise in the number of pain interventions, little has been written about the potential side effects of administering steroids into the epidural space. In fact, many premier textbooks allocate only a couple of pages to exploring glucocorticoid mechanism of action and then only briefly mention potential side effects. This lack of understanding has led many practitioners to naïvely view steroids as benign drugs without fully comprehending the broad scope of potential side effects that can occur when steroids are injected into the epidural space . . . to understand the full scope of complications that can arise from epidural administration of glucocorticoids, it is necessary not only to understand the technical/mechanical complications that occur with needle placement, but also to grasp the role of pharmacokinetics, steroid particulate size, and, most importantly, how glucocorticoids affect nearly every organ system.” Also google 1.25.12 Bloomberg News article "Bristol-Myers Warning Ignored on Steroid Shots Tied to Deaths" F 36
80 1X day
8/14/2012
 1  supposed trigger point in back Update from 7.5.12 and 7.10.12 postings: side effects of pain in extremities persist as well as extreme fatigue. Also, the injection had no therapeutic effect whatsoever. I have done quite a bit of research on Depo-Medrol and corticosteroids in general since many MDs seem clueless about the side effects of the drugs they most frequently prescribe and have no interest in problem solving. For those with an indentation from soft tissue injections, find medical article "Treatment of Local, Persistent Cutaneous Atrophy Following Corticosteroid Injection with Normal Saline Infiltration" by PETER R. SHUMAKER, MD, JAGGI RAO, MD, AND MITCHEL P. GOLDMAN, MD. The article is in the following journal: Dermatol Surg 31:10:October 2005. Apparently, saline infiltration which is easy to do, works to fix the indentation (but good luck finding a doctor who has heard of this); you should be able to find the abstract for the article online and the paper at a medical school library. A good dermatologist should know about this technique or be willing to investigate it for you. This doctor is familiar with the technique and it might be worth contacting him: MELVIN A. SHIFFMAN, MD, JD Section of Surgery, Newport Specialty Hospital, Tustin, California. For other issues such as muscle weakness, extreme fatigue, nerve issues, get your adrenal glands checked by a GOOD endocrinologist. Corticosteroids are known to interfere with adrenal gland function which can result in a host of uncomfortable to debilitating symptoms. I hope this information might help someone suffering from a terrible reaction to corticosteroid injections. F 1 days
20 1X day
7/18/2012
 1  supposed trigger point Update from 7.5.12: all side effects persist. Found out proper dosage for depo-medrol. In addition to being in the package insert material it's posted in the July 15, 2002 issue of the American Family Physician Journal (article title "Joint and Soft Tissue Injection"): 2 to 10 mg for soft tissue and small joints. So, the 20 mg I received for one trigger point (soft tissue injection) is excessive. I was told by the doctor who injected this that I was receiving a "tiny amount" of depo-medrol, and when I later complained about side effects, I was told that the dose was a "pediatric" amount. Btw, I'm under 100 lbs. and along with horrible nerve related side-effects, lost weight because of this injection. F 44 1 days
20 mg 1X day
7/10/2012
 1  supposed trigger point in back menstrual irregularities; red face and chest; extreme insomnia; pain/tingling/numbness/weakness in extremities - arms, hands, legs, feet. Just one trigger point injection of 20 mg. depo-medrol 3 1/2 months ago resulted in numerous side effects. The menstrual irregularities, red face and chest and extreme insomnia have subsided, but the pain in arms, hands, legs and feet persists and isn't letting up at all. I was told by my doctor that this was merely a "pediatric" dose and harmless. Well, not for me and it may well not be a small dose for the purposes of one trigger point injection. Corticosteroids are very potent drugs and in my experience with both depo-medrol and kenalog (also horrible side effects) doctors tend to be incredibly cavalier in administering these meds and have a collective blind spot when it comes to side effects. F 44 1 days
20 mg 1X day
7/5/2012
 4  Rheumatoid Arthritis A single Depo-Medrol injection was prescribed by my rheumy one week ago as a "bridge" to manage pain from RA until the Methotrexate and Enbrel take affect. Took 2 days to feel any benefit from the injection, but it has helped immeasurably. At day six I experienced an anxiety attack in the middle of the night with perceived difficulty breathing. I experienced this same side effect 4 years ago while taking the pill form for several weeks due to a neck injury, so I was prepared for it. If not for the anxiety attacks, I would be very satisfied with this medication. Depending on any returning pain levels as this injection wears off, I may submit to another one to continue to hold me over until the other meds kick in. Also, found the injection to have much more efficacy over the pill form. Good luck to you who are reading this and I hope this review helps you. As a footnote, I want to also mention that I am not normally prone to anxiety attacks and have only experienced them while taking Prednisone. F 46 1 days
80 mg
7/4/2012
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 5  Severe Allergies None. I have suffered with allergies my whole life. I have taken everything there is in order to make it through the day: Benedryl, Allegra, Claritin, Singulair, inhalers, ect. The DEPO shot is the only thing that has ever worked for me. I get one shot, once a year, for the past three years, and my symptoms are gone within 2 days. No more trips to ER. Thank you DEPO-MEDROL. F 40 3 years
? 1X AN
4/16/2012

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