PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  SLE No side effects ever. I was in complete remission 10 years ago and when my MD decreased my Plaquenil to once a day I went into a flare up and have not gone back into remission even when he put the Plaquenil back up to twice a day, added prednisone, added imuran. F 48 22 years
30 2X day
8/6/2010
Email
 5  Lupus Minor stomach upset the first few weeks, some gas, ringing in the ears, some hair loss but have had major benefits on this med. I've been on plaquenil for 20 years. I see an eye specialist 2x a year. Have never had a problem. I'm on 200mg once daily, taken right after breakfast. My Lupus symptoms have pretty much disappeared while on this med. I still feel some fatigue. Before plaquenil, I could barely function and could not work, had major pain and fatigue. Tried going off my med once to see how I felt. After 3 weeks, I went back on as I felt horrible. Will never try that again! F 52 20 years
2/25/2009
Email
 4  Undifferentiated interconnective di None that I remember when first taking but for approx. 8 years now I emit a BAD odour from FLATULENCE. Not the explosive kind, but seems like a slow leakage constantly, It is isolating and causes me to cancel many social functions. It was only in reading this site that I could see it may be the Plaquenil. Luckily it only became a problem towards the end of my working life. I am thankful for the way it reduced my pain & stiffness and gave me back my mobility and energy (if I also balance my life properly). Just want to know HOW to get rid of the flatulence side effect - and does Plaquenil cause a yeast overwgrowth? F 68 18 years
400mg 1X day
9/24/2011
Email
 3  RA Plaquenil worked for me since 1989. My eyes were regularly monitored and up until this past August, they were fine. I now have to be taken off the Plaquenil, as I have toxicity in my retinas. I was told in the beginning to just keep having my eyes monitored and I would be fine. My eyes are NOT fine. F 42 18 years
3/13/2007
 3  RA Plaquenil worked for me since 1989. My eyes were regularly monitored and up until this past August, they were fine. I now have to be taken off the Plaquenil, as I have toxicity in my retinas. I was told in the beginning to just keep having my eyes monitored and I would be fine. My eyes are NOT fine. F 42 18 years
3/13/2007
 5  Inflammatory rheumatism none that I notice I was in agony before taking it. Took about a month to kick in and it has saved my life and career. I have my eyes checked six-monthly but have had no problems. M 64 17 years
40mg 1X day
9/14/2011
Email
 4  Sjogren's Syndrome Started with name brand, then switched to generic. After several refills, I noticed that I was feeling like I wasn't taking any all at. My rheumatologist said that some patients do not do well on the generic, so she put me back on the name brand. I've been taking Plaquenil for 16 years, and except for the generic not being effective for me, I've had no problems. If I forget to take it, I can definitely feel it! I've always gone in for twice-yearly eye exams and so far, I'm doing very well and even my ophthalmologist is very surprised. Make sure your ophthalmologist does the "vision field" test every year as problems with peripheral vision is the most likely sign of damage from Plaquenil. F 68 16 years
200 MG 2X day
5/3/2013
Email
 5  SLE I have had no side effects. It took a few months before I got the full benefit. I believe this medication gave me by life back. I have tried to go off a few times over the years but my symptoms always increase, ie. joint pain, mouth sores, sunburn/rashes, fatigue worsens. I no longer try to go off and my rheumatologist and I agree that I'll have my eyes checked regularly and stay on it as long as it works. F 49 15 years
200 2X day
5/16/2010
 5  SLE I saw no improvement to extreme fatigue, weakness, body aches, headaches, joint pain until about 5 months after taking Plaquenil. Dose of 400mg a day. I too, tried to discontinue this drug and after 3 weeks I could not get out of bed. My original symptoms were back and felt worse because I had lived without them for several years. Please be very careful with the eye exams. I had some brief episodes of blindness and more indepth testing was done (ERG) and this detected Plaquenil toxicity. I am told it has progressed to 'irreversible' state. If caught before any symptoms can be reversible for most patients. I was very diligent in getting eye exams every 6 months. F 52 15 years
3/17/2009
 5  SLE It's been too long to remember. Similar side effects to what everyone describes, hair loss etc. Can't live without it. Felt so much better after many years and tried going down from 400 to 200mg. What a huge mistake. I though I was going to die. Had severe dizziness, numbness and tingeling, dull headache, ringing in ears, fatique,arthritus and joint pain like never before.Why did'nt my Dr. say this might happen. Was I a guenapig??? Relieved to hear this has happened to other. Also I took this through both pregnencies fine. I WILL NEVER GO OFF, unless my vision gets effected. F 42 15 years
11/23/2008
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 5  RA None of note. Has worked very well for me in conjunction with methotrexate. I live a fairly normal life. F 37 15 years
9/24/2002
Email
 4  SLE,Osteoarthritis,Rhumetoid Arthri Dilated Cardiomyopathy after 15+ years on Plaquenil. Started taking Plaquenil to get weened off of Prednisone. Have only been able to get down to 10mgs of Prednisone. Joint pain increases any lower. On Prednisone 30 years. F 52 15 years
1/31/2005
 1  rheumatoid arthritis After being told to have my retinas checks twice a year which I did and the retina tests supposedly coming back fine, I now have plaquenil retinopathy in BOTH eyes. This came on very sudden. I would like to know if anyone out there has ever filed a civil lawsuit because of this drug. F 45 15 years
400 1X day
4/15/2010
Email
 3  SLE/MCTD Developed gastro-reflux, more pain, ulcer, dark pimples on face, peeling rash on hands and feet(not sure whether from plaquenil or condition), red spots on legs, bruises(not sure how I got them), rash above ears at base of hairline, and a foul body odor. I took plaquenil for 13 years. After having a foul body odor for over 3 years, I stopped taking the medication. The odor stopped. My doctor has prescribed other drugs for me. I hope and pray they will help with very little side effects. F 55 13 years
12/25/2005
 1  lupus cardiomyopathy after taking plaquenil for 12 years i find out i do not have lupus.my dr. at the Mayo clinic took me off plaquenil. I now have what is called a hard heart,the blood is not pumped out like it should causing irregular heart beats with water build up around the heart and lungs. My comment is be sure of your diagnosis. Do you have lupus? F 78 12 years
2/11/2004
 1  RA Bullseye maculopothy. I've lost most of my central vision in both eyes. I experienced white flashes which my ophthalmologist dismissed. Within a few months, the blindness occurred suddenly. I had retinal examinations twice a year. I have good peripheral vision, a large doughnut shape of no vision, and a tiny area of poor central vision. Blindness stinks. This drug was not worth this. F 54 12 years
200 mg 2X day
9/5/2010
 5  ra none dr. said only use the name brand.... said many patients on the generic had severe problems. Use with 2mg. prednisome and am in remission (for many years) F 63 11 years
200 1X day
6/10/2015
 5  Lupus I have been taking this for more than 20yrs. If you give it a chance barring side effects it does work. I got a little diarrhea at beginning but calms down. Best to start slow then increase. I have tried not to take it and my joints get very bad. I am faithful about eye exams. Very satisfied. F 56 10 years
200 2xd
7/18/2012
 5  Mixed Connective Tissue Disease Few side effects exist that I can specifically attribute to Plaquenil but currently having substantial problems with short-term memory and decreased ability to concentrate. Would love to know if other users (especially long-term users) are having similar problems, to determine if Plaquenil is reason. Plaquenil has helped me manage a Lupus-type condition for many years. I have fewer flare-ups and overall have become more stable each year. F 35 10 years
8/27/2002
Email
 4  RA None that I could link directly to this drug. I currently discontinued use of plaquenil and noticed a large amount of fever and sweating. I guess I have been on it for so long I didnt realize it's benefits. F 22 10 years
3/4/2002
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

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