PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Psoriatic arthritis Caused a breakout of itchy hives/psoriasis. I stopped the med but the itchy spots and flare has not gone away. It's been @2 weeks since I stopped the med. I hope the side effects go away soon! F 53 30 days
200 mg 1X day
6/15/2023
Email
 1  Fibromyalgia Autoimmune High anxiety, panic attacks, low appetite, fast heart rate, & dry mouth. I am now off of it. Not sure if I will take this again. Praying that I feel normal again soon. F 40 2 months
200mg 2X day
11/17/2022
Email
 1  no reason heart side effects, dizzy, blurred vision, lightheadedness, chest palpitations fast heart rate, high blood pressure, chest pain, left arm pain, everywhere pain, tingling, shortness of breath took this drug and it was horrible, been 35 days without taking it wondering how long i have to wait for sides to clear M 21 30 days
200mg 3X M
1/24/2021
Email
 1  Dermatomyositis/ connective tissue After taking plaquenil about a week, I started itching all over my entire body. Noticed a severe rash. My skin felt hot to the touch. Went to dermatomyositis who said stop taking it and did a biopsy to confirm I was allergic to the drug. Nine days later and not any better. Back to dr who said it may take weeks to get out of my system. I'm rotating ice packs throughout my body. This is the worse nightmare of my life. Unbearable itching from my head to top of my legs keeping me awake all night... please let this end soon. F 81 8 days
200
6/24/2020
Email
 1  Rheumatoid Arthritis The first day I took it, I just didn't feel right. I had abdominal cramps and nausea. On the 4th day, I had had a severe headache for 3 days. That evening, I started wheezing, couldn't catch my breath, felt like a weight on my chest, rash on neck and face. I started taking benadryl and albuteral puffer because I couldn't breathe. I felt like I had a focal seizure. I finally got myself under control late that night. I didn't take it the next day, but I felt like I had the flu. I couldn't get out of bed. My eyes would barely open and felt like they were raw. I'm on my 4th day off of it and I'm just now feeling a little better. Still no energy and I'm having muscle shakes. I'm still having wheezing and hard time breathing. Also, on the few days I was on it, my BP and hear rate were high. I could hear my heart beat loud in my ears. Anyone else experience this? I have tried to get in touch with my Rheumatologist with no luck. I'm scared to try to take it anymore. F 47 4 days
400 mg a d
6/3/2020
Email
 1  RA It’s one thing to be in chronic pain after being on this drug for about five or six weeks now and the only side effect I have is a bad one!!! it hasn’t helped my pain from rheumatoid oh but my hair is falling out ,isn’t that lovely! Besides being in pain I can look at how ugly I am now with all my hair falling it’s just a horrible way to feel,, specially being female to lose your hair and be in pain every day! RA sucks and so does all the medication that they come up with ,,were guinea pigs!! 😢😞 Can someone tell me if their hair loss stops or does it continue until you’re bald??? Also, my eye doctor is aghast that I’m on this medication seeing I’ve had many issues with my eyes!! 62 6 weeks
200
12/11/2019
Email
 1  Autoimmune flare My appendix ruptured. My doctor gave the credit for me surviving to God. PLAQUENIL is a synthetic Quinilone, belongs in the Floro Quinilone family which has a black box warning by the FDA. I did not this at the time i took it. Previously had bad tendon damage with Cipro. F 66 15 days
2- 200mg
8/6/2019
Email
 1  lupus Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me (and 6 in every 1000 patients, new research shows) to have toxic maculopathy it caused. *re: even if you quit taking the drug, it can continue to damage the eye until blindness occurs. If you are taking it, make sure your physician is using the NEW guidelines on treatment ==I think it is no more than 5 milligrams per kilogram (For example just heard an example on this video if under 140 pounds you shouldn’t be on 400 miligrams —https://www.youtube.com/watch?v=D35uZA-vjPY ) Friends: If you have ANY changes in your vision, friends, head to a retinal specialist--1 test I had an angiogram done. My first retina specialist said i could be blind in 20 years without telling me the odds of that happening or giving me hope My 2nd retina specialist doctor thinks that, since I have had very little deterioration since stopping the drug 18 months ago, I may be one of the fortunate ones that only have some damage. All I thought Plaquenil could do to my eyes was to cause them to lose color vision. I never truly understand what the Humphrey Visual Field Test was (and it is very rudimentary, my current retina specialist doctor said. If you have ANY changes on this test, be accessed by to a retinal specialist It did work well to make my Lupus/Scleroderma is more symptomatic Are there any support groups or experimental therapies for toxic maculopathy? *I am looking for experimental treatments or for information sharing on this! +++++++++++++++ I found EyePromise Restore Vitamins that I take for retina health== those particular vitamins seems highly rated on all websites and that my retina specialist recommends —they are backed by 2 studies cited on their website called the Ares studies *Website for vitamins: www.eyepromise.com I take these eye vitamins I take to remediate future damage beyond what Plaquenil has done to my retina/macula (I have toxic maculopathy) I researched them thoroughly and they seem very legitimate. I am not paid and do not have any interest in selling EyePromise fyi! F 51
1X day
1/12/2019
Email
 1  Sarcoidosis I feel fatigue and my heart is racing and feel achy all the time.I am taking 400mg daily.and my blood pressure fluctuates. I have intermediate uveitis and I am worried what it is going to also do to my eyes F 45 5 months
1/23/2018
Email
 1  Seronegative arthritis Extreme anxiety, felt like I was going crazy, depression, low blood sugar, weight loss, panic attack with palpitations, extreme fatigue. Felt absolutely awful. And now I have to wait for it to get out of my system with a ridiculous 1/2 life of 50 days!! F 43 21 days
400m daily
7/27/2017
 1  Possible Connective Tissue Disorder Unbearable rash and hives. I look like I have the worst sunburn ever. Every crease in my body like behind knees and elbows hurt like a sunburn. My skin is peeling with scabs. I started having a rash and hives on my upper body about a week after starting Plaquenil but I thought it had to do also with a prednisone pack I had been on. I then started to get redness all over my body which was hot to touch on Thanksgiving. I went to the emergency room thinking it was something I had eaten. ER Dr. stated it was hives. I was given a shot of steroids, benadryl and I was to take 40mg of Prednisone for the next 4 days without a tamper down. The rash/hives got worse over the last few days. The Monday after Thanksgiving I went to my GP and she sent me to my Dermatologist immediately. I told him i felt like it was from the Plaquenil he agreed. I came off of it that day and my symptoms have gotten worse. I have had biopsies of my skin but still waiting for the results. I was told this is going to take over a month to get out of my system. This is a nightmare. F 54 30 days
200mg 2X day
12/7/2016
Email
 1  Possible Connective Tissue Disorder Unbearable rash and hives. I look like I have the worst sunburn ever. Every crease in my body like behind knees and elbows hurt like a sunburn. My skin is peeling with scabs. I started having a rash and hives on my upper body about a week after starting Plaquenil but I thought it had to do also with a prednisone pack I had been on. I then started to get redness all over my body which was hot to touch on Thanksgiving. I went to the emergency room thinking it was something I had eaten. ER Dr. stated it was hives. I was given a shot of steroids, benadryl and I was to take 40mg of Prednisone for the next 4 days without a tamper down. The rash/hives got worse over the last few days. The Monday after Thanksgiving I went to my GP and she sent me to my Dermatologist immediately. I told him i felt like it was from the Plaquenil he agreed. I came off of it that day and my symptoms have gotten worse. I have had biopsies of my skin but still waiting for the results. I was told this is going to take over a month to get out of my system. This is a nightmare. F 54 30 days
200mg 2X day
12/7/2016
Email
 1  Sjogrens Rheumatologist prescribed Plaquenil for inflamation due to autoimmune disorder. On third day, I developed an itchy bright red rash on neck. Stopped medication and started taking Benadryl for the itch. Two days later the rash spread to my chest, stomach, and back. Went to urgent care where I was told it was most likely a reaction to the Plaquenil. Received a cortisone shot and a prescription for Prednisolone (six day pack), and an antihistamine. When I asked the urgent care doctor how long it would take to clear, he said that it was going to get worse before it got better. Well, true statement on his part! The itchy rash moved all over body except legs and feet. My face has peeled as if I was sunburned (face did not itch but was red and a bit swollen). Two weeks later, and after a follow up with an allergist and primary care physician, I am still itchy and the rash is starting to disappear. My scalp has been very itchy and flaky and lots of hair loss when I brushed after washing my hai F 63 3 days
200 mg 2X day
9/19/2016
Email
 1  Connective tissue It has given me pain in stomach,loose bowels,nausa & vomiting.Cannot eat,thirst,severe headaches, damage to my retina. Also induced cataract.Eye pain blurry vision, dizziness, photosensitivity so bad I wear sunglasses in side. It made me so weak and sweating with crying spells.This is a terrible drug my RA did not warn me permanent damage. My primary pulled me off. Ra doc should try this med him self.It may be good for some but toxic for me.It did nothing for pain.Do not use this drug and if you do be aware. How long will this stay in my system. How much damage has it caused drug induced. Thank God for my primary taking the time to figure this out. 61 6 weeks
200mg
9/10/2016
Email
 1  Sjogren's & RA Terrible drug. Increase in all-over horrible pain, more eye pain, pain in face, increase in weakness, terrible dizziness, emotional, wanted to cry, agitated, , more balance issues. Stopped taking it and can't wait for it to clear system. Will try taking anti-inflamatories although they cause me colon issues, they can't be as bad as this nasty drug. F 68 2 months
200 1X day
7/14/2016
 1  lupus Bad mood swings,anxiety,night sweats,insomnia,headache,bloating,wind,sensitive to sunlight,hair thinning and getting lighter,fast heart rate,difficulty breathing and chest congestion,pain in arms and lower legs. Absolutely horrible drug. F 44 3 years
400mg
6/29/2016
 1  Sjogrens Diarrhea, blinding headaches, eye pain and dimmed vision, insomia,itching everywhere, ears ringing, emotional, muscle weakness, dizziness Yes it helped within a week of taking it for joint pain but the side effects were overwhelming F 40 3 weeks
400mg
6/15/2016
 1  systemic lupus Omgosh....hyper,extreme anxiety,excessive talking and hard to get to sleep Rhem said it would help with pain and lupus hurting my organs. F 47 2 weeks
200mg
5/4/2016
Email
 1  Linear Scleroderma Horrible rash covering face and body that does not respond to Prednisone or antihistamines as well as bloating and pain in ribs. This drug is like poison. I was at the doctor, ER and dermatologist and the rash is getting worse. I can't go out in public. I've been off Plaquenil for 6 days and the rash is getting worse. I was told by the ER that the half life of the drug is 50 days, which means it takes 50 days for 1/2 of the drug to leave your system. Please do your research on this drug before taking it and make sure the benefits are worth the risks. F 51 20 days
300 MG 1X day
4/12/2016
 1  ra Agitation,stomach cramps,brainfog,itchiness,fatigued,overall joint pain worst than I had previously felt. Not myself,in there but no input? I was using generic brand until 3 days ago. Food tastes lousy lost weight.I quit cold turkey is that wise now I feel good.I can think& discern.Please answer the question and what is yhe connection between hydroxychloroquine and summer and winter. Oh!I forgot the sweats. side effects need to be made aware of not trial and error of individuals! F 69 2 months
200mg dail
3/12/2016
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

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