IMIPRAMINE HYDROCHLORIDE Reviews (IMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.5 (106 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

IMIPRAMINE HCL  (IMIPRAMINE HYDROCHLORIDE):  This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.   FDA Approval Date: 1990-06-05 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on IMIPRAMINE HYDROCHLORIDE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR IMIPRAMINE HYDRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Insomnia and adhd Difficulty recalling names , places, tremors, pain while ejaculation. Post ejaculation. I think you are better off it then on it. I am going to taper it by 50 mg for 10 days (2 divided doses) 25 mg for 15 days and then off it. M 22 2 months
50
6/9/2020
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 1  Depression Used to take tofrinal- with imipramine it causes insomnia- tofrinal let me great great sleep. Ask pharmacy how much brand tofrinal would be and they told me $500- what a scam. F 60 2 days
10mg
7/8/2017
 1  Pudendal Neuralgia I just reviewed this drug a few months ago, and I decided to try it again. The entire experience was vastly different. Yes, it helped my nerve pain, and it made it so I could barely feel my physical therapist touching a huge trigger point. But I couldn't THINK or FEEL. I felt apathetic yet agitated. And the best part? Gray poop with bright red blood in it. What even. F 23 1 days
25 1X day
6/29/2014
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 1  Overactive bladder constipation, terrible morning depression - I could hardly get out of bed I was taking IMIPRAMINE HCL for overactive bladder issues. Having had depression for a long time I figured it might help since it is also used as an antidepressant. In preparation for some surgery I stopped taking the IMIPRAMINE HCL and within a week of stopping it I noticed that I no longer was waking up really depressed and not wanting to get out of bed. I started just waking up "normally" and didn't fear the morning anymore. M 63 365 days
75 1X day
8/18/2013
 1  urinary incontinence doctor prescribed 50 mg per day, with no gradual introduction of drug; noticed immediately increased agitation; anxiety; dry mouth; bitter taste in mouth; impulsive behavior; suicidal thoughts; memory loss; ended up in emergency room for suicidal rant, worsened by drinking alcohol F 67 3.5 weeks
25 mg 2X day
3/18/2012
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 1  Panic disorder I started Imipramine about 6 weeks ago ans began with 25 mg a day for 7 days then upped it to 50 mg for the rest of the duration per doc's orders. After 4 weeks I was getting excited and not the good kind then 5 weeks I had more panic attacks back to back then I ever had before in my life. Then week 6 I wanted to die, I called my Doc and told them I couldnt leave the house I was so bad I couldnt sleep and I had around a dozen panic attacks per day. Scared me so bad that I really thought I was going to be hospitalized. Luckily I began to taper off 4 days before my emergency visit with the Doc and today Im back in Zoloft, this time I will deal with the sexual side effects b/c being in panic mode 24/7 is not cool and makes you wish you were dead. Now since Ive been weeing off of Imipramine I have had these terrible headaches but eveyone is different and the reason I was prescribed Imipramine is b/c I "failed" about 7 other anti-depressants. But this one is by far the worst I have ever and I mean ever had to deal with. Now with the help of 5mg of Xanax and my zoloft on the rise and EFT techniques and CBT therapy and Faith in God I am just starting to see the light, also I quit drinking and using tobacco 3 years ago all on my own and that was like taking a piss compared to the Imipramine reaction I experienced. But Im not a D-bag and I know everyone reacts differently to each Anti-depressant so that is just my story with this med. Im an OIF Veteran and struggling everyda M 27 6 weeks
50mg
1/7/2012
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 1  sleep I gained 20 lbs, had severe dizziness upon rising, dry mouth F 48 3 years
150MG
12/7/2011
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 1  Trouble swallowing food Can no longer ejoculate I took it for swallowing difficulty. I still cannot swallow food or beverages, but now I cannot ejoculate. I am getting off of this drug now, M 49 30 days
25mg 1X day
10/23/2011
 1  Depression Racing heart, suicidal thoughts, rage, nervous feeling, hyperarousal, adrenaline surges This antidepressant made me SO MUCH MORE DEPRESSED. I guess because I have paradoxical reactions to all psych meds. I had psychotic symptoms as well as manic symptoms. It made me suicidal, very rageful too. I also felt hyperaroused (and was misdiagnosed as having PTSD), extremely anxious, could not sleep well while on it, had adrenaline surges which made me angry for no reason. Withdrawal has been very painful too both physically and psychologically, but I am having windows where I feel like myself again and it gives me hope. F 34 3 months
75 mg 1X day
9/26/2011
 1  Narcolepsy Nightmares and Night Terrors I started taking this drug to augment other medications I take for Narcolepsy - my daytime wakefulness is well controlled but I need a sleep aid. I have never had nightmares; I've had bad dreams but I would never have categorized them as nightmares. In the six weeks I've been taking Imipramine I've woken up almost nightly from the most vivid and tragic dreams drenched in sweat, out of breath, thrashing, and sobbing. This morning I woke at 1am from a horrible dream to find that I was beating myself in the face and head with my fists. The prescribing sleep medicine specialist dismissed my concerns and I will be seeing another doctor today - bruised face and all. Side effects be damned - I will NEVER take another, single Imipramine pill ever again! F 37 6 weeks
100mg 1X day
2/3/2011
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 1  i had the jitters real bad dry mouth,slow pee, when i had sex and climaxed man did it hurt in a weird place under my testis . Gave me the jitters and bad bad anxiety. imipramine did not work for me ..Good luck M 35 2 months
150mg 1X day
4/20/2010
 1  depression, urinary frequency Seemed to make me jittery, which is odd for an antidepresant People react differently to all ADs. My doc hoped this would help me sleep, relieve depression and anxiety, lessen my trips to the bathroom, but "None of the above." I gather it does work for many people. If you want a TCA (tricyclic anti-depressant) be aware that Wal-Mart, Target, etc have several for $4 per month, while imipramine costs a lot more. M 52 1 months
20mg 1X day
3/3/2010
 1  mild depression and restless leg s dry mouth, dizzyness, can hardly urinate, bad taste in mouth, destroys sex life, severe loss of memory lasting about 2 hours resulting in trip to emergency room W/EKG, BRAIN SCAN, BLOOD WORK< all checked out normal.ER Doctor said this is a dangerous drug. Constipation. I also had bad head shocks a couple times a week, usually in the evening. I stoped this medication after taking it for about three months at 50 mg each night. I tappered off by dropping to 25mg for about a week and then to 12mg for a coupled af days stopping about a week ago. I feel much better. Some side effects are still with me but think in a week or so they should be gone. On the plus side it cured, while taking it, my restless leg syndrome and dryed up a post nasel drip that i've had for a long time and all signs of my mild depression. But the side effects we're not worth it. IF nessessery I'll try something else. M 73 90 days
7/11/2009
 1  depression dangerous lowering of blood pressure, fainting I took it about a week and noticed dizziness, but no big deal. Then, for 3 days straight, I fainted every time I stood up or sat up. F 16 10 days
12/2/2007
 1  depression depression Generic did not work. Switched back to Tofranil. Reported to FDA, nothing done. M 35 3 months
5/21/2007
 1  post prostatectomy Had the opposite effect of increasing rather than decreasing incontinence M 62 6 days
8/10/2006
 1  Post Prostactomy incontinence Headaches, stomach cramps, constipation, muscle cramps, insomnia and indigestion. 50mg dose reduced to 25mg some improvement but for what little improvrmrnt in incontinence there was the side effects proved to be more detrimental than its benefits. I've flushed the remainder of my 90 day supply. M 63 6 days
6/18/2006
 1  misdiagnosed bipolarism crying, violent behavior It caused me to suffer incomprehensible bouts of depression. I usually wound up crying for hours in a dark corner. After punching a friend in the face I finally realized the drug was at fault and stopped taking it. The symptoms went away at once. This happened when I was in my teens. M 31 4 weeks
11/22/2005
 1  Anti-depressant Bad sexual side effects, as in the male anatomy, inability to have sex. M 38 2 months
3/7/2002
 2  Depression, anxiety I recently went off prozac because my depression came back stronger after about 3 months on. I went from Cymbalta to several others but after 2 weeks on this I feel like there's just no hope for me at all. I want to feel myself again but all this switching meds and the horrible side effects it's not worth it. Just 2 weeks on this medicine I don't experience and change. With menopause,hypothyroidism, depression,anxiety,and panic attacks. I'm just a guinea pig. Hope this helps someone F 47 2 weeks
50mg
3/12/2017
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IMIPRAMINE HCL  (IMIPRAMINE HYDROCHLORIDE):  This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.   FDA Approval Date: 1990-06-05 (Sources: U.S. Centers for Medicare Services, FDA)

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